azathioprine has been researched along with Chemical and Drug Induced Liver Injury, Chronic in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Chemical and Drug Induced Liver Injury, Chronic: Liver disease lasting six months or more, caused by an adverse effect of a drug or chemical. The adverse effect may be caused by drugs, drug metabolites, chemicals from the environment, or an idiosyncratic response.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Acute cholestasis is one of the most common forms of hepatotoxicity induced by azathioprine." | 4.12 | Severe azathioprine-induced liver injury 22 months after initiation of treatment. ( Battezzati, PM; Cataletti, G; Pastorelli, L; Santagata, F, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meunier, L | 1 |
| Malezieux, E | 1 |
| Bozon, A | 1 |
| Meszaros, M | 1 |
| Larrey, D | 1 |
| Björnsson, HK | 1 |
| Björnsson, ES | 1 |
| Cataletti, G | 1 |
| Santagata, F | 1 |
| Pastorelli, L | 1 |
| Battezzati, PM | 1 |
3 other studies available for azathioprine and Chemical and Drug Induced Liver Injury, Chronic
| Article | Year |
|---|---|
Can azathioprine prevent infliximab-induced liver injury?
Topics: Antibodies, Monoclonal; Azathioprine; Chemical and Drug Induced Liver Injury, Chronic; Humans; Immun | 2022 |
Reply to: "Can azathioprine prevent infliximab-induced liver injury?"
Topics: Azathioprine; Chemical and Drug Induced Liver Injury, Chronic; Gastrointestinal Agents; Humans; Immu | 2022 |
Severe azathioprine-induced liver injury 22 months after initiation of treatment.
Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chroni | 2022 |