azathioprine has been researched along with Chagas Disease in 7 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The main obstacle is Chagas' disease reactivation (CDR), usually associated to high doses of immunosuppressants." | 1.91 | Survival of Heart Transplant Patients with Chagas' Disease Under Different Antiproliferative Immunosuppressive Regimens. ( Avila, MS; Bacal, F; Barone, F; Campos, IW; Fukushima, J; Furquim, SR; Gaiotto, FA; Galante, MC; Galbiati, LC; Mangini, S; Marcondes-Braga, FG; Ohe, LA; Paulo, ARDSA; Seguro, LFBDC; Strabelli, TMV, 2023) |
| "Chagas disease is a zoonosis caused by the protozoan Trypanosoma cruzi." | 1.38 | Reactivation of Chagas disease by immunosuppressive therapy in a patient with systemic lupus erythematosus: report of an exceptional case. ( Burgos, LG; Canese, A; Melo, M; Ojeda, A; Ortiz, BD, 2012) |
| "Latent Trypanosoma cruzi infection may be reactivated in immunosuppressed individuals, with unusual clinical patterns, such as meningoencephalitis, pseudo neoplastic lesions in the central nervous system, and myocarditis with numerous parasites in the heart muscle." | 1.30 | Influence of treatment with immunosuppressive drugs in mice chronically infected with Trypanosoma cruzi. ( Andrade, SG; Andrade, ZA; Carneiro Filho, A; de Lima, ES; de Souza, AJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Furquim, SR | 1 |
| Galbiati, LC | 1 |
| Avila, MS | 1 |
| Marcondes-Braga, FG | 1 |
| Fukushima, J | 1 |
| Mangini, S | 1 |
| Seguro, LFBDC | 1 |
| Campos, IW | 1 |
| Strabelli, TMV | 1 |
| Barone, F | 1 |
| Paulo, ARDSA | 1 |
| Ohe, LA | 1 |
| Galante, MC | 1 |
| Gaiotto, FA | 1 |
| Bacal, F | 1 |
| Canese, A | 2 |
| Di Martino Ortiz, B | 1 |
| González Burgos, L | 1 |
| Centurión, MÉ | 1 |
| Burgos, LG | 1 |
| Ortiz, BD | 1 |
| Ojeda, A | 1 |
| Melo, M | 1 |
| Bocchi, EA | 1 |
| Bellotti, G | 1 |
| Uip, D | 1 |
| Kalil, J | 1 |
| de Lourdes Higuchi, M | 1 |
| Fiorelli, A | 1 |
| Stolf, N | 1 |
| Jatene, A | 1 |
| Pilleggi, F | 1 |
| Vazquez, MC | 1 |
| Sabbatiello, R | 1 |
| Schiavelli, R | 1 |
| Maiolo, E | 1 |
| Jacob, N | 1 |
| Pattin, M | 1 |
| Rearte, A | 1 |
| Andrade, SG | 1 |
| Carneiro Filho, A | 1 |
| de Souza, AJ | 1 |
| de Lima, ES | 1 |
| Andrade, ZA | 1 |
| Brener, Z | 1 |
| Chiari, E | 1 |
7 other studies available for azathioprine and Chagas Disease
| Article | Year |
|---|---|
Survival of Heart Transplant Patients with Chagas' Disease Under Different Antiproliferative Immunosuppressive Regimens.
Topics: Azathioprine; Chagas Disease; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppress | 2023 |
[Cutaneous involvement in systemic Chagas disease in immunocompromised patient].
Topics: Adult; Azathioprine; Chagas Disease; Female; Humans; Immunocompromised Host; Immunosuppressive Agent | 2012 |
Reactivation of Chagas disease by immunosuppressive therapy in a patient with systemic lupus erythematosus: report of an exceptional case.
Topics: Adult; Azathioprine; Biopsy; Chagas Disease; Female; Humans; Immunosuppressive Agents; Lupus Erythem | 2012 |
Long-term follow-up after heart transplantation in Chagas' disease.
Topics: Actuarial Analysis; Adrenal Cortex Hormones; Adult; Azathioprine; Chagas Cardiomyopathy; Chagas Dise | 1993 |
Chagas disease and transplantation.
Topics: Adult; Antilymphocyte Serum; Argentina; Azathioprine; Cadaver; Chagas Disease; Child; Cyclosporine; | 1996 |
Influence of treatment with immunosuppressive drugs in mice chronically infected with Trypanosoma cruzi.
Topics: Animals; Antibodies, Helminth; Azathioprine; Betamethasone; Brain; Chagas Disease; Chronic Disease; | 1997 |
The effects of some immunosuppressive agents in experimental chronic Chagas's disease.
Topics: Acute Disease; Animals; Azathioprine; Chagas Disease; Cyclophosphamide; Immunity; Immunosuppression | 1971 |