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azathioprine and Chagas Cardiomyopathy

azathioprine has been researched along with Chagas Cardiomyopathy in 3 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.

Research Excerpts

ExcerptRelevanceReference
" After our early experience with group 1, we attempted to use a lower cyclosporine dosage in group 2."1.29Heart transplantation for chronic Chagas' heart disease. ( Amato-Neto, V; Bacal, F; Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, AD; Mocelin, AO; Pileggi, F; Stolf, NA; Uip, D, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bacal, F2
Silva, CP1
Bocchi, EA3
Pires, PV1
Moreira, LF1
Issa, VS1
Moreira, SA1
das Dores Cruz, F1
Strabelli, T1
Stolf, NA2
Ramires, JA1
Bellotti, G2
Uip, D2
Kalil, J1
de Lourdes Higuchi, M1
Fiorelli, A2
Stolf, N1
Jatene, A1
Pilleggi, F1
Mocelin, AO1
Higuchi, ML1
Amato-Neto, V1
Jatene, AD1
Pileggi, F1

Other Studies

3 other studies available for azathioprine and Chagas Cardiomyopathy

ArticleYear
Mychophenolate mofetil increased chagas disease reactivation in heart transplanted patients: comparison between two different protocols.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:8

    Topics: Adolescent; Adult; Aged; Azathioprine; Chagas Cardiomyopathy; Dose-Response Relationship, Drug; Fema

2005
Long-term follow-up after heart transplantation in Chagas' disease.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Actuarial Analysis; Adrenal Cortex Hormones; Adult; Azathioprine; Chagas Cardiomyopathy; Chagas Dise

1993
Heart transplantation for chronic Chagas' heart disease.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:6

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Cause of Death; Chagas Cardiomyopathy; Child; C

1996