azathioprine has been researched along with Central Nervous System Diseases in 28 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypoparathyroidism is rare in patients with systemic lupus erythematosus (SLE)." | 2.46 | Hypoparathyroidism in a patient with systemic lupus erythematosus coexisted with ankylosing spondylitis: a case report and review of literature. ( Dai, X; Jiang, L; Liu, J; Ma, L; Yu, F, 2010) |
| "Azathioprine was the treatment prescribed in the four patients with NMOSD." | 1.51 | Inflammatory demyelinating diseases of the central nervous system in Niger. ( Adehossi Omar, É; Assadeck, H; Douma Maiga, D; Hassane Djibo, F; Mamadou, Z; Toudou Daouda, M, 2019) |
| "Infliximab is increasingly used to treat neurosarcoidosis." | 1.51 | Infliximab biosimilar for treating neurosarcoidosis: tolerance and efficacy in a retrospective study including switch from the originator and initiation of treatment. ( Amoura, Z; Benameur, N; Cohen Aubart, F; Cotteret, C; Haroche, J; Hie, M; Junot, H; Mathian, A; Miyara, M; Riller, Q; Tilleul, P, 2019) |
| "Patients who developed renal and CNS disease more than 1 year after diagnosis had higher SLEDAI scores at disease onset." | 1.35 | Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study. ( Benseler, SM; Harvey, E; Hebert, D; Hiraki, LT; Silverman, ED; Tyrrell, PN, 2008) |
| "Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare disorder characterized by a bleeding tendency due to factor II deficiency associated with the presence of lupus anticoagulant (LAC) autoantibodies." | 1.33 | Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome. ( Rich, E; Senécal, JL; Vinet, E, 2006) |
| "Of 66 patients with systemic lupus erythematosus (SLE), 11 (16." | 1.27 | Livedoid vasculitis and central nervous system involvement in systemic lupus erythematosus. ( Yasue, T, 1986) |
| "Forty-nine patients with systemic lupus erythematosus (SLE) during childhood and adolescence presenting over a period of 17 years were followed during treatment with prednisone and azathioprine." | 1.26 | Systemic lupus erythematosus within the first two decades of life. ( Blau, EB; Burke, BA; Fish, AJ; Michael, AF; Vernier, RL; Westberg, NG, 1977) |
| " Functional psychosis was usually preciptated by corticsoteroid therapy and respond to a reduction in steroid dosage and administration of psychotropic drugs." | 1.25 | Central nervous system disease in systemic lupus erythematosus. Therapy and prognosis. ( Klempner, MS; Lipsky, BA; Lockshin, MD; Sergent, JS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menzel, C | 1 |
| Niederle, P | 1 |
| Zorger, N | 1 |
| Assadeck, H | 1 |
| Toudou Daouda, M | 1 |
| Adehossi Omar, É | 1 |
| Mamadou, Z | 1 |
| Hassane Djibo, F | 1 |
| Douma Maiga, D | 1 |
| Riller, Q | 1 |
| Cotteret, C | 1 |
| Junot, H | 1 |
| Benameur, N | 1 |
| Haroche, J | 1 |
| Mathian, A | 1 |
| Hie, M | 1 |
| Miyara, M | 1 |
| Tilleul, P | 1 |
| Amoura, Z | 1 |
| Cohen Aubart, F | 1 |
| Hou, X | 1 |
| Wang, X | 1 |
| Xie, B | 1 |
| Lin, W | 1 |
| Liu, J | 2 |
| Ma, D | 1 |
| Zhang, HL | 1 |
| Inan, AS | 1 |
| Masatlıoglu, S | 1 |
| Ozyurek, SC | 1 |
| Engin, D | 1 |
| Erdem, I | 1 |
| Jiang, L | 1 |
| Dai, X | 1 |
| Ma, L | 1 |
| Yu, F | 1 |
| Hasiloglu, ZI | 1 |
| Albayram, S | 1 |
| Tasmali, K | 1 |
| Erer, B | 1 |
| Selcuk, H | 1 |
| Islak, C | 1 |
| Studer, U | 1 |
| Ruehe, B | 1 |
| Waldegg, G | 1 |
| Vajtai, I | 1 |
| Escher, R | 1 |
| Aeberli, D | 1 |
| Skowasch, D | 1 |
| Pabst, S | 1 |
| Wilhelm, K | 1 |
| Grohé, C | 1 |
| Le Guenno, G | 1 |
| Galicier, L | 1 |
| Uro-Coste, E | 1 |
| Petitcolin, V | 1 |
| Rieu, V | 1 |
| Ruivard, M | 1 |
| Vinet, E | 1 |
| Rich, E | 1 |
| Senécal, JL | 1 |
| Rózsa, A | 1 |
| Sztankaninecz, Y | 1 |
| Gács, G | 1 |
| Magyar, T | 1 |
| Hiraki, LT | 1 |
| Benseler, SM | 1 |
| Tyrrell, PN | 1 |
| Hebert, D | 1 |
| Harvey, E | 1 |
| Silverman, ED | 1 |
| Hornstein, OP | 1 |
| Djawari, D | 1 |
| Druschky, A | 1 |
| Heckmann, JG | 1 |
| Druschky, K | 1 |
| Huk, WJ | 1 |
| Erbguth, F | 1 |
| Neundörfer, B | 1 |
| Bresnihan, B | 1 |
| Grigor, RR | 1 |
| Hughes, GR | 1 |
| McGeown, MG | 1 |
| Douglas, JF | 1 |
| Brown, WA | 1 |
| Donaldson, RA | 1 |
| Kennedy, JA | 1 |
| Loughridge, WG | 1 |
| Mehta, S | 1 |
| Hill, CM | 1 |
| Fish, AJ | 1 |
| Blau, EB | 1 |
| Westberg, NG | 1 |
| Burke, BA | 1 |
| Vernier, RL | 1 |
| Michael, AF | 1 |
| Bennahum, DA | 1 |
| Messner, RP | 1 |
| Sergent, JS | 1 |
| Lockshin, MD | 2 |
| Klempner, MS | 1 |
| Lipsky, BA | 1 |
| Hahn, BH | 1 |
| Avioli, LV | 1 |
| Martinez, JM | 1 |
| Barraquer-Bordas, L | 1 |
| Ferrer, I | 1 |
| Escartin, AE | 1 |
| Rosich, M | 1 |
| Barraquer-Feu, ML | 1 |
| Yasue, T | 1 |
| Cendrowski, W | 1 |
| Riekkinen, PJ | 1 |
| Rinne, UK | 1 |
| Baker, M | 1 |
| Hadler, NM | 1 |
| Whitaker, JN | 1 |
| Dunner, DL | 1 |
| Gerwin, RD | 1 |
| Decker, JL | 1 |
| Kagen, LJ | 1 |
| Brendel, W | 1 |
| Seifert, J | 1 |
| Lob, G | 1 |
| Peermohamed, AR | 1 |
| Shafar, J | 1 |
5 reviews available for azathioprine and Central Nervous System Diseases
| Article | Year |
|---|---|
Horizontal eyeball akinesia as an initial manifestation of CLIPPERS: Case report and review of literature.
Topics: Anti-Inflammatory Agents; Azathioprine; Central Nervous System Diseases; Diagnosis, Differential; Di | 2016 |
Hypoparathyroidism in a patient with systemic lupus erythematosus coexisted with ankylosing spondylitis: a case report and review of literature.
Topics: Adult; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Glucocorticoids; Humans; Hyp | 2010 |
[Non-infectious oral aphthous disorders. 2. Behçet's syndrome (malignant aphthosis)].
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Bone Diseases; Central Nervous System Diseas | 1980 |
Recent observations on central nervous system lupus erythematosus.
Topics: Animals; Antibodies, Viral; Autoantibodies; Azathioprine; Central Nervous System Diseases; Child; Co | 1975 |
Immunosuppressive therapy in neurological diseases.
Topics: Adrenocorticotropic Hormone; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Cytara | 1974 |
1 trial available for azathioprine and Central Nervous System Diseases
| Article | Year |
|---|---|
Psychopathology in systemic lupus erythematosus. II. Relation to clinical observations, corticosteroid administration, and cerebrospinal fluid C4.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Affective Symptoms; Azathioprine; Brain Diseases; Centra | 1973 |
22 other studies available for azathioprine and Central Nervous System Diseases
| Article | Year |
|---|---|
Topics: Aged; Azathioprine; Capillary Permeability; Central Nervous System Diseases; Chronic Disease; Diagno | 2018 |
Inflammatory demyelinating diseases of the central nervous system in Niger.
Topics: Adult; Aged; Azathioprine; Central Nervous System Diseases; Demyelinating Diseases; Disability Evalu | 2019 |
Infliximab biosimilar for treating neurosarcoidosis: tolerance and efficacy in a retrospective study including switch from the originator and initiation of treatment.
Topics: Adult; Antirheumatic Agents; Azathioprine; Biosimilar Pharmaceuticals; Central Nervous System Diseas | 2019 |
Unusual central nervous system involvement of rheumatoid arthritis: successful treatment with steroid and azathioprine.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Central Nervous System Diseases; Dr | 2011 |
A case of primary Sjögren's syndrome presenting primarily with central nervous system vasculitic involvement.
Topics: Adult; Angiography, Digital Subtraction; Azathioprine; Brain; Central Nervous System Diseases; Diagn | 2012 |
Atypical presentation of Behçet's disease with central nervous system involvement successfully treated with infliximab.
Topics: Adult; Antibodies, Monoclonal; Azathioprine; Behcet Syndrome; Biopsy; Central Nervous System Disease | 2012 |
[Diabetes insipidus due to neurosarcoidosis].
Topics: Adult; Anti-Inflammatory Agents; Antidiuretic Agents; Azathioprine; Biopsy; Central Nervous System D | 2011 |
Successful treatment with azathioprine of relapsing Rosai-Dorfman disease of the central nervous system.
Topics: Azathioprine; Central Nervous System Diseases; Comorbidity; Crohn Disease; Follow-Up Studies; Histio | 2012 |
Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome.
Topics: Adrenal Cortex Hormones; Antiphospholipid Syndrome; Azathioprine; Central Nervous System Diseases; C | 2006 |
[Uncommon manifestation of central nervous system sarcoidosis].
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Central Nervous System Diseases; Female; Humans; Magne | 2007 |
Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study.
Topics: Adolescent; Age of Onset; Antimalarials; Autoantibodies; Azathioprine; Central Nervous System Diseas | 2008 |
Severe neurological complications of ulcerative colitis.
Topics: Adult; Azathioprine; Central Nervous System Diseases; Colitis, Ulcerative; Cyclosporine; Drug Therap | 2002 |
Lymphocytotoxic antibodies in systemic lupus erythematosus: their clinical significance.
Topics: Antilymphocyte Serum; Azathioprine; Binding Sites, Antibody; Central Nervous System Diseases; Comple | 1979 |
Low dose steroid from the day following renal transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Central Nervous System Diseases; Child; Colonic Neoplasms; Do | 1979 |
Systemic lupus erythematosus within the first two decades of life.
Topics: Adolescent; Azathioprine; Central Nervous System Diseases; Child; Child, Preschool; Female; Follow-U | 1977 |
Central nervous system disease in systemic lupus erythematosus. Therapy and prognosis.
Topics: Adolescent; Adult; Azathioprine; Central Nervous System Diseases; Female; Humans; Lupus Erythematosu | 1975 |
Clinical conference: lupus erythematosus.
Topics: Adult; Anticonvulsants; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Female; Hum | 1975 |
[Anatomo-clinical study of Behçet's syndrome with involvement of the central nervous system].
Topics: Azathioprine; Behcet Syndrome; Brain; Central Nervous System Diseases; Humans; Lymphocytes; Magnetic | 1988 |
Livedoid vasculitis and central nervous system involvement in systemic lupus erythematosus.
Topics: Adult; Azathioprine; Betamethasone; Blood Vessels; Central Nervous System Diseases; Cyclophosphamide | 1986 |
Meningitic reactions after azathioprine.
Topics: Adult; Azathioprine; Central Nervous System Diseases; Diagnosis, Differential; Female; Humans; Lupus | 1972 |
Effect of 'maximum immune suppression' with thoracic duct drainage, ALG, azathioprine and cortisone in some neurological disorders.
Topics: Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Central Nervous System Diseases; Cortisone; | 1972 |
Sustained azathioprine-induced remission in Wegener's granulomatosis.
Topics: Azathioprine; Central Nervous System Diseases; Drug Synergism; Female; Granulomatosis with Polyangii | 1969 |