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azathioprine and Central Nervous System Disease

azathioprine has been researched along with Central Nervous System Disease in 28 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Hypoparathyroidism is rare in patients with systemic lupus erythematosus (SLE)."2.46Hypoparathyroidism in a patient with systemic lupus erythematosus coexisted with ankylosing spondylitis: a case report and review of literature. ( Dai, X; Jiang, L; Liu, J; Ma, L; Yu, F, 2010)
"Azathioprine was the treatment prescribed in the four patients with NMOSD."1.51Inflammatory demyelinating diseases of the central nervous system in Niger. ( Adehossi Omar, É; Assadeck, H; Douma Maiga, D; Hassane Djibo, F; Mamadou, Z; Toudou Daouda, M, 2019)
"Infliximab is increasingly used to treat neurosarcoidosis."1.51Infliximab biosimilar for treating neurosarcoidosis: tolerance and efficacy in a retrospective study including switch from the originator and initiation of treatment. ( Amoura, Z; Benameur, N; Cohen Aubart, F; Cotteret, C; Haroche, J; Hie, M; Junot, H; Mathian, A; Miyara, M; Riller, Q; Tilleul, P, 2019)
"Patients who developed renal and CNS disease more than 1 year after diagnosis had higher SLEDAI scores at disease onset."1.35Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study. ( Benseler, SM; Harvey, E; Hebert, D; Hiraki, LT; Silverman, ED; Tyrrell, PN, 2008)
"Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare disorder characterized by a bleeding tendency due to factor II deficiency associated with the presence of lupus anticoagulant (LAC) autoantibodies."1.33Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome. ( Rich, E; Senécal, JL; Vinet, E, 2006)
"Of 66 patients with systemic lupus erythematosus (SLE), 11 (16."1.27Livedoid vasculitis and central nervous system involvement in systemic lupus erythematosus. ( Yasue, T, 1986)
"Forty-nine patients with systemic lupus erythematosus (SLE) during childhood and adolescence presenting over a period of 17 years were followed during treatment with prednisone and azathioprine."1.26Systemic lupus erythematosus within the first two decades of life. ( Blau, EB; Burke, BA; Fish, AJ; Michael, AF; Vernier, RL; Westberg, NG, 1977)
" Functional psychosis was usually preciptated by corticsoteroid therapy and respond to a reduction in steroid dosage and administration of psychotropic drugs."1.25Central nervous system disease in systemic lupus erythematosus. Therapy and prognosis. ( Klempner, MS; Lipsky, BA; Lockshin, MD; Sergent, JS, 1975)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199014 (50.00)18.7374
1990's0 (0.00)18.2507
2000's4 (14.29)29.6817
2010's10 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Menzel, C1
Niederle, P1
Zorger, N1
Assadeck, H1
Toudou Daouda, M1
Adehossi Omar, É1
Mamadou, Z1
Hassane Djibo, F1
Douma Maiga, D1
Riller, Q1
Cotteret, C1
Junot, H1
Benameur, N1
Haroche, J1
Mathian, A1
Hie, M1
Miyara, M1
Tilleul, P1
Amoura, Z1
Cohen Aubart, F1
Hou, X1
Wang, X1
Xie, B1
Lin, W1
Liu, J2
Ma, D1
Zhang, HL1
Inan, AS1
Masatlıoglu, S1
Ozyurek, SC1
Engin, D1
Erdem, I1
Jiang, L1
Dai, X1
Ma, L1
Yu, F1
Hasiloglu, ZI1
Albayram, S1
Tasmali, K1
Erer, B1
Selcuk, H1
Islak, C1
Studer, U1
Ruehe, B1
Waldegg, G1
Vajtai, I1
Escher, R1
Aeberli, D1
Skowasch, D1
Pabst, S1
Wilhelm, K1
Grohé, C1
Le Guenno, G1
Galicier, L1
Uro-Coste, E1
Petitcolin, V1
Rieu, V1
Ruivard, M1
Vinet, E1
Rich, E1
Senécal, JL1
Rózsa, A1
Sztankaninecz, Y1
Gács, G1
Magyar, T1
Hiraki, LT1
Benseler, SM1
Tyrrell, PN1
Hebert, D1
Harvey, E1
Silverman, ED1
Hornstein, OP1
Djawari, D1
Druschky, A1
Heckmann, JG1
Druschky, K1
Huk, WJ1
Erbguth, F1
Neundörfer, B1
Bresnihan, B1
Grigor, RR1
Hughes, GR1
McGeown, MG1
Douglas, JF1
Brown, WA1
Donaldson, RA1
Kennedy, JA1
Loughridge, WG1
Mehta, S1
Hill, CM1
Fish, AJ1
Blau, EB1
Westberg, NG1
Burke, BA1
Vernier, RL1
Michael, AF1
Bennahum, DA1
Messner, RP1
Sergent, JS1
Lockshin, MD2
Klempner, MS1
Lipsky, BA1
Hahn, BH1
Avioli, LV1
Martinez, JM1
Barraquer-Bordas, L1
Ferrer, I1
Escartin, AE1
Rosich, M1
Barraquer-Feu, ML1
Yasue, T1
Cendrowski, W1
Riekkinen, PJ1
Rinne, UK1
Baker, M1
Hadler, NM1
Whitaker, JN1
Dunner, DL1
Gerwin, RD1
Decker, JL1
Kagen, LJ1
Brendel, W1
Seifert, J1
Lob, G1
Peermohamed, AR1
Shafar, J1

Reviews

5 reviews available for azathioprine and Central Nervous System Disease

ArticleYear
Horizontal eyeball akinesia as an initial manifestation of CLIPPERS: Case report and review of literature.
    Medicine, 2016, Volume: 95, Issue:34

    Topics: Anti-Inflammatory Agents; Azathioprine; Central Nervous System Diseases; Diagnosis, Differential; Di

2016
Hypoparathyroidism in a patient with systemic lupus erythematosus coexisted with ankylosing spondylitis: a case report and review of literature.
    Joint bone spine, 2010, Volume: 77, Issue:6

    Topics: Adult; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Glucocorticoids; Humans; Hyp

2010
[Non-infectious oral aphthous disorders. 2. Behçet's syndrome (malignant aphthosis)].
    Fortschritte der Medizin, 1980, Nov-27, Volume: 98, Issue:44

    Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Bone Diseases; Central Nervous System Diseas

1980
Recent observations on central nervous system lupus erythematosus.
    Seminars in arthritis and rheumatism, 1975, Volume: 4, Issue:3

    Topics: Animals; Antibodies, Viral; Autoantibodies; Azathioprine; Central Nervous System Diseases; Child; Co

1975
Immunosuppressive therapy in neurological diseases.
    Annals of clinical research, 1974, Volume: 6, Issue:6

    Topics: Adrenocorticotropic Hormone; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Cytara

1974

Trials

1 trial available for azathioprine and Central Nervous System Disease

ArticleYear
Psychopathology in systemic lupus erythematosus. II. Relation to clinical observations, corticosteroid administration, and cerebrospinal fluid C4.
    Seminars in arthritis and rheumatism, 1973, Volume: 3, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Affective Symptoms; Azathioprine; Brain Diseases; Centra

1973

Other Studies

22 other studies available for azathioprine and Central Nervous System Disease

ArticleYear
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2018, Volume: 190, Issue:6

    Topics: Aged; Azathioprine; Capillary Permeability; Central Nervous System Diseases; Chronic Disease; Diagno

2018
Inflammatory demyelinating diseases of the central nervous system in Niger.
    Revue neurologique, 2019, Volume: 175, Issue:4

    Topics: Adult; Aged; Azathioprine; Central Nervous System Diseases; Demyelinating Diseases; Disability Evalu

2019
Infliximab biosimilar for treating neurosarcoidosis: tolerance and efficacy in a retrospective study including switch from the originator and initiation of treatment.
    Journal of neurology, 2019, Volume: 266, Issue:5

    Topics: Adult; Antirheumatic Agents; Azathioprine; Biosimilar Pharmaceuticals; Central Nervous System Diseas

2019
Unusual central nervous system involvement of rheumatoid arthritis: successful treatment with steroid and azathioprine.
    Rheumatology international, 2011, Volume: 31, Issue:10

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Central Nervous System Diseases; Dr

2011
A case of primary Sjögren's syndrome presenting primarily with central nervous system vasculitic involvement.
    Rheumatology international, 2012, Volume: 32, Issue:3

    Topics: Adult; Angiography, Digital Subtraction; Azathioprine; Brain; Central Nervous System Diseases; Diagn

2012
Atypical presentation of Behçet's disease with central nervous system involvement successfully treated with infliximab.
    Rheumatology international, 2012, Volume: 32, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Behcet Syndrome; Biopsy; Central Nervous System Disease

2012
[Diabetes insipidus due to neurosarcoidosis].
    Pneumologie (Stuttgart, Germany), 2011, Volume: 65, Issue:8

    Topics: Adult; Anti-Inflammatory Agents; Antidiuretic Agents; Azathioprine; Biopsy; Central Nervous System D

2011
Successful treatment with azathioprine of relapsing Rosai-Dorfman disease of the central nervous system.
    Journal of neurosurgery, 2012, Volume: 117, Issue:3

    Topics: Azathioprine; Central Nervous System Diseases; Comorbidity; Crohn Disease; Follow-Up Studies; Histio

2012
Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome.
    The Journal of rheumatology, 2006, Volume: 33, Issue:10

    Topics: Adrenal Cortex Hormones; Antiphospholipid Syndrome; Azathioprine; Central Nervous System Diseases; C

2006
[Uncommon manifestation of central nervous system sarcoidosis].
    Ideggyogyaszati szemle, 2007, Jan-20, Volume: 60, Issue:1-2

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Central Nervous System Diseases; Female; Humans; Magne

2007
Clinical and laboratory characteristics and long-term outcome of pediatric systemic lupus erythematosus: a longitudinal study.
    The Journal of pediatrics, 2008, Volume: 152, Issue:4

    Topics: Adolescent; Age of Onset; Antimalarials; Autoantibodies; Azathioprine; Central Nervous System Diseas

2008
Severe neurological complications of ulcerative colitis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2002, Volume: 9, Issue:1

    Topics: Adult; Azathioprine; Central Nervous System Diseases; Colitis, Ulcerative; Cyclosporine; Drug Therap

2002
Lymphocytotoxic antibodies in systemic lupus erythematosus: their clinical significance.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1979, Volume: 13

    Topics: Antilymphocyte Serum; Azathioprine; Binding Sites, Antibody; Central Nervous System Diseases; Comple

1979
Low dose steroid from the day following renal transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16

    Topics: Adolescent; Adult; Aged; Azathioprine; Central Nervous System Diseases; Child; Colonic Neoplasms; Do

1979
Systemic lupus erythematosus within the first two decades of life.
    The American journal of medicine, 1977, Volume: 62, Issue:1

    Topics: Adolescent; Azathioprine; Central Nervous System Diseases; Child; Child, Preschool; Female; Follow-U

1977
Central nervous system disease in systemic lupus erythematosus. Therapy and prognosis.
    The American journal of medicine, 1975, Volume: 58, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Central Nervous System Diseases; Female; Humans; Lupus Erythematosu

1975
Clinical conference: lupus erythematosus.
    Archives of internal medicine, 1975, Volume: 135, Issue:12

    Topics: Adult; Anticonvulsants; Azathioprine; Central Nervous System Diseases; Cyclophosphamide; Female; Hum

1975
[Anatomo-clinical study of Behçet's syndrome with involvement of the central nervous system].
    Revue neurologique, 1988, Volume: 144, Issue:2

    Topics: Azathioprine; Behcet Syndrome; Brain; Central Nervous System Diseases; Humans; Lymphocytes; Magnetic

1988
Livedoid vasculitis and central nervous system involvement in systemic lupus erythematosus.
    Archives of dermatology, 1986, Volume: 122, Issue:1

    Topics: Adult; Azathioprine; Betamethasone; Blood Vessels; Central Nervous System Diseases; Cyclophosphamide

1986
Meningitic reactions after azathioprine.
    The New England journal of medicine, 1972, Jun-15, Volume: 286, Issue:24

    Topics: Adult; Azathioprine; Central Nervous System Diseases; Diagnosis, Differential; Female; Humans; Lupus

1972
Effect of 'maximum immune suppression' with thoracic duct drainage, ALG, azathioprine and cortisone in some neurological disorders.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:6

    Topics: Antilymphocyte Serum; Autoimmune Diseases; Azathioprine; Central Nervous System Diseases; Cortisone;

1972
Sustained azathioprine-induced remission in Wegener's granulomatosis.
    British medical journal, 1969, Dec-06, Volume: 4, Issue:5683

    Topics: Azathioprine; Central Nervous System Diseases; Drug Synergism; Female; Granulomatosis with Polyangii

1969