Page last updated: 2024-10-23

azathioprine and Cataract

azathioprine has been researched along with Cataract in 22 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" These studies provide a compelling case for a re-evaluation of the long-term use of glucocorticoids in SLE, focusing on minimizing glucocorticoid exposure as part of the strategy to improve long-term outcomes."2.55It hasn't gone away: the problem of glucocorticoid use in lupus remains. ( Apostolopoulos, D; Morand, EF, 2017)
" The corticosteroid dosage was proportional to each patient's weight."1.26Reversibility of corticosteroid-associated cataracts in children with the nephrotic syndrome. ( Forman, AR; Loreto, JA; Tina, LU, 1977)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199012 (54.55)18.7374
1990's5 (22.73)18.2507
2000's2 (9.09)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Apostolopoulos, D1
Morand, EF1
Ramaiya, KJ1
Rao, PK1
Sreekantam, S1
Denniston, AK1
Murray, PI1
Manrique, J1
Rossich, E1
Hernández Sierra, A1
Adhikary, HP1
Sells, RA1
Basu, PK1
Ponticelli, C1
Civati, G1
Tarantino, A1
Quarto di Palo, F1
Corbetta, G1
Minetti, L1
Vegeto, A1
Belli, L1
Karia, N1
Doran, J1
Watson, SL1
Nischal, K1
Nakamura, T1
Sasaki, H1
Nagai, K1
Fujisawa, K1
Sasaki, K2
Suzuki, K1
Tsugawa, R1
Ticho, U1
Durst, A1
Licht, A1
Berkowitz, S1
Forman, AR1
Loreto, JA1
Tina, LU1
Koch, HR2
Weikenmeier, P1
Siedek, M1
Nishimoto, K1
Yamamura, T1
Ishikawa, I1
Shinoda, A1
Apaydin, C1
Gur, B1
Yakupoglu, G1
Saka, O1
Dróbecka-Brydakowa, E1
Hockwin, O1
Ballinger, WF1
Lacy, PE1
Goldschmidt, E1
Lochte, J1
Astle, JN1
Ellis, PP2
Bell, MJ1
Martin, LW1
Gonzales, LL1
McEnery, PT1
West, CD1
Belzer, FO1
Schweitzer, RT1
Holliday, M1
Kountz, SL1
Fine, RN1
Korsch, BM1
Brennan, LP1
Edelbrock, HH1
Stiles, QR1
Riddell, HI1
Weitzman, JJ1
Mickelson, JC1
Tucker, BL1
Grushkin, CM1
Hovland, KR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression[NCT00006505]Phase 26 participants (Actual)Interventional2000-11-16Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Cataract

ArticleYear
It hasn't gone away: the problem of glucocorticoid use in lupus remains.
    Rheumatology (Oxford, England), 2017, 04-01, Volume: 56, Issue:suppl_1

    Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Cardiovascular Diseases; Cata

2017

Trials

1 trial available for azathioprine and Cataract

ArticleYear
Randomized study with cyclosporine in kidney transplantation: 10-year follow-up.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Creatinine; Cyclosporine; Female; Follow-Up Studie

1996

Other Studies

20 other studies available for azathioprine and Cataract

ArticleYear
Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:1

    Topics: Acyclovir; Antiviral Agents; Azathioprine; Cataract; Drug Implants; Eye Infections, Viral; Herpes Si

2011
Survey of expert practice and perceptions of the supporting clinical evidence for the management of uveitis-related cataract and cystoid macular oedema.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Azathioprine; Cataract; Cataract Extraction;

2011
[Multiple complications after renal transplantation].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Adult; Azathioprine; Cataract; Cholecystitis; Choledocholithiasis; Cyclosporine; Femur Head Necrosis

2004
Ocular complications of systemic steroid after renal transplantation and their association with HLA.
    The British journal of ophthalmology, 1982, Volume: 66, Issue:5

    Topics: Adult; Azathioprine; Cataract; Eye Diseases; Female; HLA Antigens; Humans; Kidney Failure, Chronic;

1982
Surgically induced necrotizing scleritis in a patient with ankylosing spondylitis.
    Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cataract; Cataract Extraction; Diplopia

1999
[Influence of cyclosporin on steroid-induced cataract].
    Nippon Ganka Gakkai zasshi, 2001, Volume: 105, Issue:7

    Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Cyclosporine; Female; Humans; Immunosuppressive Ag

2001
Steroid-induced glaucoma and cataract in renal transplant recipients.
    Israel journal of medical sciences, 1977, Volume: 13, Issue:9

    Topics: Administration, Oral; Adult; Azathioprine; Cataract; Female; Glaucoma; Humans; Immunosuppression The

1977
Reversibility of corticosteroid-associated cataracts in children with the nephrotic syndrome.
    American journal of ophthalmology, 1977, Volume: 84, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Cataract; Child; Child, Preschool; Cycloph

1977
[Corticosteroid cataracts following kidney transplantation. Investigations on the influence of additional factors upon the development of opacities (author's transl)].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1975, Volume: 194, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Azathioprine; Cataract; Female; Graft Rejection; Humans

1975
Cataract in renal transplantation recipients with combination ciclosporin treatment.
    Lens and eye toxicity research, 1992, Volume: 9, Issue:3-4

    Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Cyclosporine; Drug Therapy, Combination; Female; F

1992
Ocular and visual side effects of systemic cyclosporine.
    Annals of ophthalmology, 1992, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Azathioprine; Cataract; Cyclosporine; Female; Follow-Up Studies; Glucocorticoids;

1992
[Effect of immunosuppressive treatment on the crystalline lenses of patients after kidney transplantation].
    Klinika oczna, 1991, Volume: 93, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cataract; Cyclosporine; Dose-Response Relatio

1991
[Iatrogenic cataracts].
    Medizinische Klinik, 1974, Oct-18, Volume: 69, Issue:42

    Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth

1974
Transplantation of intact pancreatic islets in rats.
    Surgery, 1972, Volume: 72, Issue:2

    Topics: Animals; Azathioprine; Blood Glucose; Cataract; Diabetes Complications; Diabetes Mellitus; Glycosuri

1972
Treatment of a case of sympathetic ophthalmia.
    Acta ophthalmologica. Supplementum, 1974, Volume: 123

    Topics: Acetates; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cataract; Child; Chlorambuci

1974
Ocular complications in renal transplant patients.
    Annals of ophthalmology, 1974, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov

1974
Alternate-day single-dose prednisone therapy: a method of reducing steroid toxicity.
    Journal of pediatric surgery, 1972, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Bacterial Infections; Bone Diseases; Cataract; Child; Child, Presch

1972
Renal homotransplantation in children.
    American journal of surgery, 1972, Volume: 124, Issue:2

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Cataract; Child; Child, Preschool; Evaluation Studie

1972
Renal transplantation in young children.
    American journal of surgery, 1973, Volume: 125, Issue:5

    Topics: Age Factors; Azathioprine; Bone Diseases; Cadaver; Cataract; Child; Child, Preschool; Epiphyses, Sli

1973
Ocular changes in renal transplant patients.
    American journal of ophthalmology, 1967, Volume: 63, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Cataract; Child; Epinephrine; Female; Glaucoma

1967