azathioprine has been researched along with Cataract in 22 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " These studies provide a compelling case for a re-evaluation of the long-term use of glucocorticoids in SLE, focusing on minimizing glucocorticoid exposure as part of the strategy to improve long-term outcomes." | 2.55 | It hasn't gone away: the problem of glucocorticoid use in lupus remains. ( Apostolopoulos, D; Morand, EF, 2017) |
| " The corticosteroid dosage was proportional to each patient's weight." | 1.26 | Reversibility of corticosteroid-associated cataracts in children with the nephrotic syndrome. ( Forman, AR; Loreto, JA; Tina, LU, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (54.55) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apostolopoulos, D | 1 |
| Morand, EF | 1 |
| Ramaiya, KJ | 1 |
| Rao, PK | 1 |
| Sreekantam, S | 1 |
| Denniston, AK | 1 |
| Murray, PI | 1 |
| Manrique, J | 1 |
| Rossich, E | 1 |
| Hernández Sierra, A | 1 |
| Adhikary, HP | 1 |
| Sells, RA | 1 |
| Basu, PK | 1 |
| Ponticelli, C | 1 |
| Civati, G | 1 |
| Tarantino, A | 1 |
| Quarto di Palo, F | 1 |
| Corbetta, G | 1 |
| Minetti, L | 1 |
| Vegeto, A | 1 |
| Belli, L | 1 |
| Karia, N | 1 |
| Doran, J | 1 |
| Watson, SL | 1 |
| Nischal, K | 1 |
| Nakamura, T | 1 |
| Sasaki, H | 1 |
| Nagai, K | 1 |
| Fujisawa, K | 1 |
| Sasaki, K | 2 |
| Suzuki, K | 1 |
| Tsugawa, R | 1 |
| Ticho, U | 1 |
| Durst, A | 1 |
| Licht, A | 1 |
| Berkowitz, S | 1 |
| Forman, AR | 1 |
| Loreto, JA | 1 |
| Tina, LU | 1 |
| Koch, HR | 2 |
| Weikenmeier, P | 1 |
| Siedek, M | 1 |
| Nishimoto, K | 1 |
| Yamamura, T | 1 |
| Ishikawa, I | 1 |
| Shinoda, A | 1 |
| Apaydin, C | 1 |
| Gur, B | 1 |
| Yakupoglu, G | 1 |
| Saka, O | 1 |
| Dróbecka-Brydakowa, E | 1 |
| Hockwin, O | 1 |
| Ballinger, WF | 1 |
| Lacy, PE | 1 |
| Goldschmidt, E | 1 |
| Lochte, J | 1 |
| Astle, JN | 1 |
| Ellis, PP | 2 |
| Bell, MJ | 1 |
| Martin, LW | 1 |
| Gonzales, LL | 1 |
| McEnery, PT | 1 |
| West, CD | 1 |
| Belzer, FO | 1 |
| Schweitzer, RT | 1 |
| Holliday, M | 1 |
| Kountz, SL | 1 |
| Fine, RN | 1 |
| Korsch, BM | 1 |
| Brennan, LP | 1 |
| Edelbrock, HH | 1 |
| Stiles, QR | 1 |
| Riddell, HI | 1 |
| Weitzman, JJ | 1 |
| Mickelson, JC | 1 |
| Tucker, BL | 1 |
| Grushkin, CM | 1 |
| Hovland, KR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression[NCT00006505] | Phase 2 | 6 participants (Actual) | Interventional | 2000-11-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Cataract
| Article | Year |
|---|---|
It hasn't gone away: the problem of glucocorticoid use in lupus remains.
Topics: Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Azathioprine; Cardiovascular Diseases; Cata | 2017 |
1 trial available for azathioprine and Cataract
| Article | Year |
|---|---|
Randomized study with cyclosporine in kidney transplantation: 10-year follow-up.
Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Creatinine; Cyclosporine; Female; Follow-Up Studie | 1996 |
20 other studies available for azathioprine and Cataract
| Article | Year |
|---|---|
Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant.
Topics: Acyclovir; Antiviral Agents; Azathioprine; Cataract; Drug Implants; Eye Infections, Viral; Herpes Si | 2011 |
Survey of expert practice and perceptions of the supporting clinical evidence for the management of uveitis-related cataract and cystoid macular oedema.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Azathioprine; Cataract; Cataract Extraction; | 2011 |
[Multiple complications after renal transplantation].
Topics: Adult; Azathioprine; Cataract; Cholecystitis; Choledocholithiasis; Cyclosporine; Femur Head Necrosis | 2004 |
Ocular complications of systemic steroid after renal transplantation and their association with HLA.
Topics: Adult; Azathioprine; Cataract; Eye Diseases; Female; HLA Antigens; Humans; Kidney Failure, Chronic; | 1982 |
Surgically induced necrotizing scleritis in a patient with ankylosing spondylitis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cataract; Cataract Extraction; Diplopia | 1999 |
[Influence of cyclosporin on steroid-induced cataract].
Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Cyclosporine; Female; Humans; Immunosuppressive Ag | 2001 |
Steroid-induced glaucoma and cataract in renal transplant recipients.
Topics: Administration, Oral; Adult; Azathioprine; Cataract; Female; Glaucoma; Humans; Immunosuppression The | 1977 |
Reversibility of corticosteroid-associated cataracts in children with the nephrotic syndrome.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Cataract; Child; Child, Preschool; Cycloph | 1977 |
[Corticosteroid cataracts following kidney transplantation. Investigations on the influence of additional factors upon the development of opacities (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Azathioprine; Cataract; Female; Graft Rejection; Humans | 1975 |
Cataract in renal transplantation recipients with combination ciclosporin treatment.
Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Cyclosporine; Drug Therapy, Combination; Female; F | 1992 |
Ocular and visual side effects of systemic cyclosporine.
Topics: Adolescent; Adult; Azathioprine; Cataract; Cyclosporine; Female; Follow-Up Studies; Glucocorticoids; | 1992 |
[Effect of immunosuppressive treatment on the crystalline lenses of patients after kidney transplantation].
Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cataract; Cyclosporine; Dose-Response Relatio | 1991 |
[Iatrogenic cataracts].
Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth | 1974 |
Transplantation of intact pancreatic islets in rats.
Topics: Animals; Azathioprine; Blood Glucose; Cataract; Diabetes Complications; Diabetes Mellitus; Glycosuri | 1972 |
Treatment of a case of sympathetic ophthalmia.
Topics: Acetates; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cataract; Child; Chlorambuci | 1974 |
Ocular complications in renal transplant patients.
Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov | 1974 |
Alternate-day single-dose prednisone therapy: a method of reducing steroid toxicity.
Topics: Adolescent; Adult; Azathioprine; Bacterial Infections; Bone Diseases; Cataract; Child; Child, Presch | 1972 |
Renal homotransplantation in children.
Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Cataract; Child; Child, Preschool; Evaluation Studie | 1972 |
Renal transplantation in young children.
Topics: Age Factors; Azathioprine; Bone Diseases; Cadaver; Cataract; Child; Child, Preschool; Epiphyses, Sli | 1973 |
Ocular changes in renal transplant patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Cataract; Child; Epinephrine; Female; Glaucoma | 1967 |