Page last updated: 2024-10-23

azathioprine and Castleman Disease

azathioprine has been researched along with Castleman Disease in 7 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Castleman Disease: Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterized by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and IMMUNOGLOBULIN A.

Research Excerpts

ExcerptRelevanceReference
"A man with multicentric angiofollicular lymph node hyperplasia and a polyclonal gammopathy developed a debilitating sensory-motor peripheral neuropathy that resolved with plasma-pheresis and immunosuppressive therapy."2.38Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review. ( May, E; Scherokman, B; Vukelja, SJ, 1991)
"Mixed Connective Tissue Disorder with Castleman's Disease is a rare association; the patient presenting with varied and interesting manifestations."1.36Mixed connective tissue disorder and Castleman's disease. ( Boorugu, HK; Chrispal, A; Thomas, EM; Vasuki, Z, 2010)
"To report a case of localized orbital Castleman's disease of mixed cell type with a follow-up of 20 years."1.31Castleman's disease in the orbit. A 20-year follow-up. ( Alyahya, GA; Heegaard, S; Prause, JU, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Irrera, M1
Bozzola, E1
Cardoni, A1
DeVito, R1
Diociaiuti, A1
El Hachem, M1
Girardi, K1
Marchesi, A1
Villani, A1
Benjamin, B1
Zaltzman, R1
Shpitz, B1
Gordon, CR1
Avital, S1
Chrispal, A1
Vasuki, Z1
Thomas, EM1
Boorugu, HK1
Műzes, G1
Sipos, F1
Csomor, J1
Sréter, L1
Alyahya, GA1
Prause, JU1
Heegaard, S1
Chan, TM1
Cheng, IK1
Wong, KL1
Chan, KW1
Scherokman, B1
Vukelja, SJ1
May, E1

Reviews

1 review available for azathioprine and Castleman Disease

ArticleYear
Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review.
    Archives of internal medicine, 1991, Volume: 151, Issue:4

    Topics: Aged; Azathioprine; Castleman Disease; Humans; Immunosuppression Therapy; Male; Peripheral Nervous S

1991

Other Studies

6 other studies available for azathioprine and Castleman Disease

ArticleYear
Paraneoplastic pemphigus and Castleman's disease: a case report and a revision of the literature.
    Italian journal of pediatrics, 2023, Mar-20, Volume: 49, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Castleman Disease; Child; Female; Humans; Pemphig

2023
Presacral Mass Discovered during Pregnancy followed by Myasthenia Gravis.
    The Israel Medical Association journal : IMAJ, 2015, Volume: 17, Issue:5

    Topics: Adult; Azathioprine; Castleman Disease; Cholinesterase Inhibitors; Female; Humans; Immunosuppressive

2015
Mixed connective tissue disorder and Castleman's disease.
    The Journal of the Association of Physicians of India, 2010, Volume: 58

    Topics: Adolescent; Azathioprine; Biopsy; Castleman Disease; Female; Glomerulonephritis, Membranoproliferati

2010
Successful tocilizumab treatment in a patient with human herpesvirus 8-positive and human immunodeficiency virus-negative multicentric Castleman's disease of plasma cell type nonresponsive to rituximab-CVP therapy.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2013, Volume: 121, Issue:7

    Topics: Adult; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cast

2013
Castleman's disease in the orbit. A 20-year follow-up.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:5

    Topics: Adult; Azathioprine; Castleman Disease; Combined Modality Therapy; Exophthalmos; Female; Follow-Up S

2002
Resolution of membranoproliferative glomerulonephritis complicating angiofollicular lymph node hyperplasia (Castleman's disease).
    Nephron, 1993, Volume: 65, Issue:4

    Topics: Adult; Azathioprine; Biopsy; Castleman Disease; Complement System Proteins; Cyclophosphamide; Drug T

1993