azathioprine has been researched along with Carditis in 75 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six patients with myocarditis documented by biopsy, after a baseline right heart catheterization and echocardiogram, underwent treatment with azathioprine and prednisone." | 7.67 | Lack of objective improvement in ventricular systolic function in patients with myocarditis treated with azathioprine and prednisone. ( Hosenpud, JD; McAnulty, JH; Niles, NR, 1985) |
| "FLM 5011 has been shown to be protective against arachidonic acid-induced bronchoconstriction in vitro and in vivo." | 6.66 | Antiinflammatory effect of a lipoxygenase inhibitor (FLM 5011) in severe active myocarditis. ( Förster, A; Geissler, W; Meyer, R; Rapoport, SM; Reisinger, I; Romaniuk, P; Schewe, T; Slapke, J, 1988) |
| "Chronic non-viral myocarditis, also called inflammatory cardiomyopathy, can be treated with immune suppression on tops of optimal medical therapy (OMT) for heart failure, using a combination of prednisolone and azathioprine (IPA)." | 5.05 | Prednisone and azathioprine in patients with inflammatory cardiomyopathy: systematic review and meta-analysis. ( Ali, O; Barradas-Pires, A; Henkens, M; Heymans, S; Negishi, K; Timmermans, P, 2020) |
| "patients were enrolled in this prospective cohort study and were treated with MMF, as the initial treatment in case of concomitant systemic immune diseases (SIDs), or as rescue therapy in isolated myocarditis intolerant/resistant to azathioprine." | 3.96 | Efficacy and safety of mycophenolate mofetil in patients with virus-negative lymphocytic myocarditis: A prospective cohort study. ( Basso, C; Campochiaro, C; Candela, C; Dagna, L; De Luca, G; Della Bella, P; Esposito, A; Palmisano, A; Peretto, G; Rizzo, S; Sala, S; Sartorelli, S; Thiene, G, 2020) |
| "Out of 652 biopsied patients, 112 had a histological diagnosis of active lymphocytic myocarditis; 41 of these 112 patients were characterized by progressive heart failure despite conventional therapy and were treated with prednisone and azathioprine for 6 months." | 3.72 | Immunosuppressive therapy for active lymphocytic myocarditis: virological and immunologic profile of responders versus nonresponders. ( Calabrese, F; Chimenti, C; Frustaci, A; Maseri, A; Pieroni, M; Thiene, G, 2003) |
| "An unusual case of giant cell myocarditis presenting with cardiogenic shock that dramatically responded to conventional dose of steroids and azathioprine is reported." | 3.70 | Giant cell myocarditis responding to immunosuppressive therapy. ( Chimenti, C; Frustaci, A; Gentiloni, N; Pieroni, M, 2000) |
| "Sixteen patients (12 male and 4 female, age 2-46 years) with endomyocardial biopsy-proven myocarditis were prospectively evaluated with immunosuppressive therapy including azathioprine and prednisolone in addition to other standard measures." | 3.68 | Immunosuppressive therapy in inflammatory myocarditis: long-term follow-up. ( Chopra, P; Dev, V; Goswami, KC; Malhotra, A; Shrivastava, S; Talwar, KK, 1992) |
| "To analyse hemodynamic parameters (left ventricles ejection fraction, cardiac index, mean pulmonary wedge pressure and left ventricle diastolic diameter, in a group of children with active myocarditis (diagnosed by endomyocardial biopsy) pre and post treatment with conventional therapy and immunosuppressive drugs (isolated prednisone or prednisone associated with azathioprine or cyclosporine)." | 3.68 | [Immunosuppressive drugs for the treatment of active myocarditis in children. Hemodynamic evaluation]. ( Albuquerque, AM; Camargo, PR; Costa, R; Ebaid, M; Higuchi, ML; Mazzieri, R; Meneghetti, C; Pileggi, F; Ratti, M; Snitcowsky, R, 1990) |
| "The immunosuppressive therapy with azathioprine or cyclosporine plus prednisone leads to decrease of active myocarditis intensity in a higher proportion of cases than the treatment with only prednisone or no immunosuppressive drugs." | 3.68 | [Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy]. ( Aiello, VD; Camargo, PR; Ebaid, M; Fiorelli, A; Higuchi, Mde L; Mazzieri, R; Pileggi, F; Snitcowsky, R, 1990) |
| "Twenty patients (13 males and seven females) with a biopsy-proven diagnosis of myocarditis underwent a period of treatment with prednisone and azathioprine." | 3.67 | Immunosuppressive treatment in myocarditis. ( Camerini, F; Di Lenarda, A; Dreas, L; Salvi, A; Silvestri, F, 1989) |
| "Thirty-four patients with history of congestive heart failure, dilated cardiomyopathy, and biopsy-proven lymphocytic myocarditis were treated for six months with immunosuppressive agents (prednisone and azathioprine) in addition to standard therapy for congestive heart failure." | 3.67 | Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents. ( Badhwar, K; Bott-Silverman, C; Hobbs, RE; Pelegrin, D; Ratliff, NB; Rincon, G; Sterba, R, 1989) |
| " Immunosuppressive therapy with prednisolone 2 mg/kg/d and azathioprine 2 mg/kg/d was added on the assumption of chronic myocarditis (n = 4) or endocardial fibrosis (n = 2)." | 3.67 | [Immunosuppressive treatment of chronic myocarditis]. ( Proll, E; Salzer-Muhar, U; Schlemmer, M; Strigl, E; Wimmer, M, 1988) |
| "Of 202 patients with dilated cardiomyopathy, 84 patients with increased HLA expression were randomized to receive either immunosuppression or placebo for 3 months; they were then followed for 2 years." | 2.70 | Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results. ( Glanowska, G; Niklewski, T; Nowalany-Kozielska, E; Polonski, L; Rozek, MM; Wilczewski, P; Wodniecki, J; Wojciechowska, C; Wojnicz, R; Zembala, M, 2001) |
| "Our results do not support routine treatment of myocarditis with immunosuppressive drugs." | 2.68 | A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators. ( Billingham, ME; Herskowitz, A; Mason, JW; McManus, BM; Moon, TE; O'Connell, JB; Rose, NR, 1995) |
| "Prednisone was administered to all patients; one patient also received azathioprine." | 2.67 | Immunosuppressive therapy in the management of acute myocarditis in children: a clinical trial. ( Benson, LN; Chan, KY; Freedom, RM; Iwahara, M; Wilson, GJ, 1991) |
| "FLM 5011 has been shown to be protective against arachidonic acid-induced bronchoconstriction in vitro and in vivo." | 2.66 | Antiinflammatory effect of a lipoxygenase inhibitor (FLM 5011) in severe active myocarditis. ( Förster, A; Geissler, W; Meyer, R; Rapoport, SM; Reisinger, I; Romaniuk, P; Schewe, T; Slapke, J, 1988) |
| "Myocarditis is defined as inflammation of the myocardium accompanied by myocellular necrosis." | 2.49 | Corticosteroids for viral myocarditis. ( Chen, HS; Liu, JP; Wang, W; Wu, SN, 2013) |
| "Myocarditis is the inflammation of the myocardial tissue, primarily caused by viral infection." | 1.43 | [Effect of immune therapy in the prognosis of viral myocarditis in pediatric patients]. ( González-Espinosa, AM; López-Gallegos, D; Márquez-González, H; Yáñez-Gutiérrez, L; Zamudio-López, JO, 2016) |
| "Endomyocarditis with mitral valve regurgitation, multiple hepatic infarction, and pulmonary hemorrhage developed later." | 1.35 | Leukocytoclastic vasculitis with severe cardiac involvement in an infant: a case report. ( Chiang, BL; Hsiao, CH; Hung, JT; Lee, JH; Wang, LC; Yang, YH; Yu, HH, 2008) |
| "Meningococcal meningitis is itself uncommon, with a morbidity of approximately 1." | 1.31 | [Secondary immunologically-caused myocarditis, pericarditis and exudative pleuritis due to meningococcal meningitis]. ( Berwing, K; Damaschke, HJ; Stange, K, 2001) |
| "In 1985, myocarditis was diagnosed by endomyocardial biopsy in a 53-year-old woman who was free of symptoms of heart insufficiency." | 1.29 | Enterovirus-induced myocarditis: hemodynamic deterioration with immunosuppressive therapy and successful application of interferon-alpha. ( Figulla, HR; Heim, A; Kandolf, R; Kreuzer, H; Stille-Siegener, M, 1994) |
| " After our early experience with group 1, we attempted to use a lower cyclosporine dosage in group 2." | 1.29 | Heart transplantation for chronic Chagas' heart disease. ( Amato-Neto, V; Bacal, F; Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, AD; Mocelin, AO; Pileggi, F; Stolf, NA; Uip, D, 1996) |
| "Biopsies then taken revealed recurrence of myocarditis in the transplanted heart." | 1.28 | Response of recurrent giant cell myocarditis in a transplanted heart to intensive immunosuppression. ( Kong, G; Madden, B; Mitchell, A; Pomerance, A; Spyrou, N; Yacoub, M, 1991) |
| "Myocarditis was strongly suspected clinically in all cases, yet was unconfirmed on initial right ventricular biopsy." | 1.28 | "Borderline" myocarditis: an indication for repeat endomyocardial biopsy. ( Dec, GW; Fallon, JT; Palacios, I; Southern, JF, 1990) |
| " The initial dosage is 1." | 1.27 | Immunosuppressive therapy in the management of biopsy proven acute myocarditis. ( Richardson, PJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (26.67) | 18.7374 |
| 1990's | 24 (32.00) | 18.2507 |
| 2000's | 14 (18.67) | 29.6817 |
| 2010's | 11 (14.67) | 24.3611 |
| 2020's | 6 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chimenti, C | 8 |
| Russo, MA | 3 |
| Frustaci, A | 8 |
| De Luca, G | 2 |
| Campochiaro, C | 2 |
| Sartorelli, S | 2 |
| Peretto, G | 3 |
| Sala, S | 2 |
| Palmisano, A | 2 |
| Esposito, A | 2 |
| Candela, C | 1 |
| Basso, C | 2 |
| Rizzo, S | 2 |
| Thiene, G | 3 |
| Della Bella, P | 2 |
| Dagna, L | 2 |
| Fanouriakis, A | 1 |
| Tziolos, N | 1 |
| Bertsias, G | 1 |
| Boumpas, DT | 1 |
| Timmermans, P | 1 |
| Barradas-Pires, A | 1 |
| Ali, O | 1 |
| Henkens, M | 1 |
| Heymans, S | 1 |
| Negishi, K | 1 |
| Barzaghi, F | 1 |
| Cicalese, MP | 1 |
| Di Resta, C | 1 |
| Slavich, M | 1 |
| Benedetti, S | 1 |
| Giangiobbe, S | 1 |
| De Cobelli, F | 1 |
| Gulletta, S | 1 |
| Casari, G | 1 |
| Aiuti, A | 1 |
| Blagova, OV | 1 |
| Aliyeva, IN | 1 |
| Nedostup, AV | 1 |
| Kogan, EA | 1 |
| Komarov, RN | 1 |
| Chernyavsky, SV | 1 |
| Seslavinskaya, VV | 1 |
| Shelukha, PA | 1 |
| Sedov, VP | 1 |
| Gagarina, NV | 1 |
| Mershina, EA | 1 |
| Sinitsyn, VE | 1 |
| Fomin, VV | 1 |
| Burke, PA | 1 |
| Malebranche, L | 1 |
| Gakhal, M | 1 |
| Rahman, E | 1 |
| Saltzberg, M | 1 |
| Chen, HS | 1 |
| Wang, W | 1 |
| Wu, SN | 1 |
| Liu, JP | 1 |
| Fozing, T | 1 |
| Zouri, N | 1 |
| Tost, A | 1 |
| Breit, R | 1 |
| Seeck, G | 1 |
| Koch, C | 1 |
| Oezbek, C | 1 |
| Mavrogeni, S | 1 |
| Ntoskas, T | 1 |
| Gialafos, E | 1 |
| Karabela, G | 1 |
| Krommida, M | 1 |
| Gatzonis, S | 1 |
| Siatouni, A | 1 |
| Kolovou, G | 1 |
| Zouvelou, V | 1 |
| Stamboulis, E | 1 |
| Ng, F | 1 |
| Chiong, FJ | 1 |
| Buchanan, R | 1 |
| Burrell, LM | 1 |
| Weitsman, T | 1 |
| Weisz, G | 1 |
| Keren, A | 1 |
| Hasin, T | 1 |
| Latushko, A | 1 |
| Ghazi, LJ | 1 |
| Márquez-González, H | 1 |
| López-Gallegos, D | 1 |
| González-Espinosa, AM | 1 |
| Zamudio-López, JO | 1 |
| Yáñez-Gutiérrez, L | 1 |
| Kadota, S | 1 |
| Takeuchi, Y | 1 |
| Izuhara, M | 1 |
| Baba, O | 1 |
| Shioji, K | 1 |
| Uegaito, T | 1 |
| Kadota, E | 1 |
| Matsuda, M | 1 |
| Cooper, LT | 2 |
| Hare, JM | 1 |
| Tazelaar, HD | 2 |
| Edwards, WD | 1 |
| Starling, RC | 1 |
| Deng, MC | 1 |
| Menon, S | 1 |
| Mullen, GM | 1 |
| Jaski, B | 1 |
| Bailey, KR | 1 |
| Cunningham, MW | 1 |
| Dec, GW | 3 |
| Pursnani, A | 1 |
| Yee, H | 1 |
| Slater, W | 1 |
| Sarswat, N | 1 |
| Daumas, A | 1 |
| Bernard, F | 1 |
| Jacquier, A | 1 |
| Rossi, P | 1 |
| Francès, Y | 1 |
| Granel, B | 1 |
| Möller, K | 1 |
| Klingel, K | 1 |
| Kaiser, U | 1 |
| Thum, M | 1 |
| Bönig, A | 1 |
| Kandolf, R | 2 |
| Hasenfuss, G | 1 |
| Scholz, KH | 1 |
| Calabrese, F | 2 |
| Pieroni, M | 5 |
| Maseri, A | 4 |
| Kotova, AA | 1 |
| Paleev, PN | 1 |
| Suchkov, SV | 1 |
| Paleev, NR | 1 |
| DEPASQUALE, NP | 1 |
| BURCH, GE | 1 |
| PENA, E | 1 |
| REEMTSMA, K | 1 |
| Hia, CP | 1 |
| Yip, WC | 1 |
| Tai, BC | 1 |
| Quek, SC | 1 |
| Kono, K | 1 |
| Salvatori, L | 1 |
| Morgante, E | 1 |
| Sale, P | 1 |
| Ferretti, E | 1 |
| Petrangeli, E | 1 |
| Gulino, A | 1 |
| Hung, JT | 1 |
| Yang, YH | 1 |
| Hsiao, CH | 1 |
| Yu, HH | 1 |
| Lee, JH | 1 |
| Wang, LC | 1 |
| Chiang, BL | 1 |
| Feneley, MP | 1 |
| Gavaghan, TP | 1 |
| Ralston, M | 1 |
| Hickie, JB | 1 |
| Baron, DW | 1 |
| Vignola, PA | 1 |
| Aonuma, K | 1 |
| Swaye, PS | 1 |
| Rozanski, JJ | 1 |
| Blankstein, RL | 1 |
| Benson, J | 1 |
| Gosselin, AJ | 1 |
| Lister, JW | 1 |
| Daly, K | 1 |
| Richardson, PJ | 2 |
| Olsen, EG | 1 |
| Morgan-Capner, P | 1 |
| McSorley, C | 1 |
| Jackson, G | 1 |
| Jewitt, DE | 1 |
| Mason, JW | 3 |
| Billingham, ME | 2 |
| Ricci, DR | 1 |
| O'Connell, JB | 2 |
| Herskowitz, A | 2 |
| Rose, NR | 1 |
| McManus, BM | 1 |
| Moon, TE | 1 |
| Gehrke, D | 1 |
| Herzum, M | 2 |
| Schönian, U | 2 |
| Klein, HH | 1 |
| Drude, L | 1 |
| Mennel, HD | 1 |
| Maisch, B | 3 |
| Hengstenberg, C | 1 |
| Hufnagel, G | 1 |
| Bethge, C | 1 |
| Bittinger, A | 1 |
| Neumann, K | 1 |
| Heim, A | 1 |
| Stille-Siegener, M | 1 |
| Kreuzer, H | 1 |
| Figulla, HR | 1 |
| Bocchi, EA | 1 |
| Bellotti, G | 2 |
| Mocelin, AO | 1 |
| Uip, D | 1 |
| Bacal, F | 1 |
| Higuchi, ML | 3 |
| Amato-Neto, V | 1 |
| Fiorelli, A | 2 |
| Stolf, NA | 1 |
| Jatene, AD | 2 |
| Pileggi, F | 4 |
| Brown, CA | 1 |
| Olszowska, M | 1 |
| Tracz, W | 1 |
| Kokoszka, M | 1 |
| Pieniazek, P | 1 |
| Przewłocki, T | 1 |
| Hlawaty, M | 1 |
| Podolec, P | 1 |
| Frasik, W | 1 |
| Lazar, A | 1 |
| Dziatkowiak, A | 1 |
| Menghini, VV | 1 |
| Savcenko, V | 1 |
| Olson, LJ | 1 |
| Kao, A | 1 |
| Gentiloni, N | 1 |
| Stange, K | 1 |
| Damaschke, HJ | 1 |
| Berwing, K | 1 |
| Wojnicz, R | 1 |
| Nowalany-Kozielska, E | 1 |
| Wojciechowska, C | 1 |
| Glanowska, G | 1 |
| Wilczewski, P | 1 |
| Niklewski, T | 1 |
| Zembala, M | 1 |
| Polonski, L | 1 |
| Rozek, MM | 1 |
| Wodniecki, J | 1 |
| Schein, PS | 1 |
| Winokur, SH | 1 |
| Dragatakis, LN | 1 |
| Klassen, J | 1 |
| Hüttner, I | 1 |
| Fraser, DG | 1 |
| Poirier, NL | 1 |
| Klassen, GA | 1 |
| Desjardins, V | 1 |
| Pelletier, G | 1 |
| Leung, TK | 1 |
| Waters, D | 1 |
| Talwar, KK | 1 |
| Goswami, KC | 1 |
| Chopra, P | 1 |
| Dev, V | 1 |
| Shrivastava, S | 1 |
| Malhotra, A | 1 |
| Jones, SR | 1 |
| Hutchins, GM | 2 |
| Baughman, KL | 2 |
| Förster, A | 2 |
| Geissler, W | 2 |
| Meyer, R | 2 |
| Romaniuk, P | 2 |
| Reisinger, I | 2 |
| Müller, S | 1 |
| Chan, KY | 1 |
| Iwahara, M | 1 |
| Benson, LN | 1 |
| Wilson, GJ | 1 |
| Freedom, RM | 1 |
| Kong, G | 1 |
| Madden, B | 1 |
| Spyrou, N | 1 |
| Pomerance, A | 1 |
| Mitchell, A | 1 |
| Yacoub, M | 1 |
| Camargo, PR | 2 |
| Mazzieri, R | 2 |
| Snitcowsky, R | 2 |
| Ratti, M | 1 |
| Costa, R | 1 |
| Albuquerque, AM | 1 |
| Meneghetti, C | 1 |
| Ebaid, M | 2 |
| Arteaga-Fernánez, E | 1 |
| Barretto, AC | 1 |
| Mady, C | 1 |
| Fiorelli, AI | 1 |
| Higuchi, Mde L | 1 |
| Aiello, VD | 1 |
| Fallon, JT | 1 |
| Southern, JF | 1 |
| Palacios, I | 1 |
| Midei, MG | 1 |
| DeMent, SH | 1 |
| Feldman, AM | 1 |
| Kumada, T | 1 |
| Kawai, C | 1 |
| Bilińska, ZT | 1 |
| Ruzyłło, W | 1 |
| Lubiszewska, B | 1 |
| Gajewski, W | 1 |
| Salvi, A | 1 |
| Di Lenarda, A | 1 |
| Dreas, L | 1 |
| Silvestri, F | 1 |
| Camerini, F | 1 |
| Hobbs, RE | 1 |
| Pelegrin, D | 1 |
| Ratliff, NB | 1 |
| Bott-Silverman, C | 1 |
| Rincon, G | 1 |
| Sterba, R | 1 |
| Badhwar, K | 1 |
| Leroy, O | 1 |
| Asseman, P | 1 |
| Traisnel, G | 1 |
| Durand, P | 1 |
| Beuscart, R | 1 |
| Dewilde, A | 1 |
| Wattré, P | 1 |
| Théry, C | 1 |
| Schewe, T | 1 |
| Rapoport, SM | 1 |
| Slapke, J | 1 |
| Wimmer, M | 1 |
| Proll, E | 1 |
| Salzer-Muhar, U | 1 |
| Schlemmer, M | 1 |
| Strigl, E | 1 |
| Hosenpud, JD | 1 |
| McAnulty, JH | 1 |
| Niles, NR | 1 |
| Solov'ev, VD | 1 |
| Gutman, NR | 1 |
| Khesin, IaE | 1 |
| Kognovitskaia, AI | 1 |
| Leandri, J | 1 |
| Cachera, JP | 1 |
| Lacombe, M | 1 |
| Vigano, M | 1 |
| Harada, S | 1 |
| Chatty, ME | 1 |
| Deodhar, SD | 1 |
| Mutz, I | 1 |
| Schröfl, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Endomyocardial Biopsy and Aetiology-based Treatment in Patients With Inflammatory Heart Disease in Arrhythmic and Non-arrhythmic Clinical Presentations: an Integrated Approach for the Optimal Diagnostic and Therapeutic Management[NCT04521790] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2018-01-30 | Recruiting | |||
| Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033] | 120 participants (Anticipated) | Interventional | 2022-08-15 | Enrolling by invitation | |||
| Single-blind, Investigator-initiated, Randomized, Controlled Trial to Assess the Safety and Efficacy of Intravenous Corticosteroid Therapy to Treat Patients With Acute Myocarditis With Mildly Reduced Left Ventricular Ejection Fraction[NCT05974462] | Phase 3 | 174 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | ||
| Giant Cell Myocarditis Treatment Trial Pilot Study[NCT00027443] | 40 participants (Anticipated) | Interventional | 2001-08-31 | Completed | |||
| RANDOMIZED, MULTICENTRIC STUDY COMPARING THE EFFECT OF TWO REGIMENS OF COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE TREATMENT OF INFLAMMATORY CARDIOMYOPATHY CZECH-ICIT (CZECH INFLAMMATORY CARDIOMYOPATHY IMMUNOSUPPRESSION TRIAL)[NCT01877746] | Phase 3 | 234 participants (Anticipated) | Interventional | 2013-01-31 | Recruiting | ||
| Cardiac Magnetic Resonance Evaluation of Myocardial Inflammation Persistence After Acute Myocarditis: Prognostic Relevance[NCT03525639] | 80 participants (Anticipated) | Interventional | 2016-12-06 | Recruiting | |||
| [NCT00000524] | Phase 2 | 0 participants | Interventional | 1986-07-31 | Completed | ||
| Single Blind Randomized Controlled Trial to Assess the Safety and Efficacy of High Dose Pulse Intravenous Corticosteroid Therapy to Treat Patients With Complicated/Fulminant Acute Myocarditis[NCT05150704] | Phase 3 | 288 participants (Anticipated) | Interventional | 2021-10-07 | Recruiting | ||
| Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry[NCT05158751] | 100 participants (Anticipated) | Observational | 2023-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for azathioprine and Carditis
| Article | Year |
|---|---|
Therapeutic strategies for virus-negative myocarditis: a comprehensive review.
Topics: Azathioprine; Cardiomyopathy, Dilated; Humans; Immunosuppressive Agents; Myocarditis; Myocardium | 2020 |
Update οn the diagnosis and management of systemic lupus erythematosus.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc | 2021 |
Prednisone and azathioprine in patients with inflammatory cardiomyopathy: systematic review and meta-analysis.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Myocarditis; Prednisone | 2020 |
Corticosteroids for viral myocarditis.
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chronic Disease; Cyclosporine; H | 2013 |
Management of a patient with eosinophilic myocarditis and normal peripheral eosinophil count: case report and literature review.
Topics: Azathioprine; Biopsy; Drug Therapy, Combination; Eosinophilia; Eosinophils; Female; Glucocorticoids; | 2014 |
Modern methods of treatment of autoimmune myocarditis.
Topics: Autoimmune Diseases; Autoimmunity; Azathioprine; Humans; Myocarditis | 2003 |
Immunosuppressive therapy in acute myocarditis: an 18 year systematic review.
Topics: Acute Disease; Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Female; H | 2004 |
[Autoimmune myocarditis].
Topics: Animals; Antigen-Presenting Cells; Autoantigens; Autoimmune Diseases; Azathioprine; CD4-Positive T-L | 2005 |
Implications of the Myocarditis Treatment Trial for clinical practice.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Cyclosporine; Female; Follow-Up Studies; Huma | 1996 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical a | 1975 |
10 trials available for azathioprine and Carditis
| Article | Year |
|---|---|
Immunosuppressive therapy in virus-negative inflammatory cardiomyopathy: 20-year follow-up of the TIMIC trial.
Topics: Azathioprine; Follow-Up Studies; Humans; Immunosuppression Therapy; Myocarditis; Prednisone; Stroke | 2022 |
Usefulness of immunosuppression for giant cell myocarditis.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Cyclosporine; Female; Giant Cells; Humans; Immunosuppr | 2008 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
Randomized study on the efficacy of immunosuppressive therapy in patients with virus-negative inflammatory cardiomyopathy: the TIMIC study.
Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Double-Blind Method; Heart Failure; Humans; | 2009 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
A clinical trial of immunosuppressive therapy for myocarditis. The Myocarditis Treatment Trial Investigators.
Topics: Adult; Autoantibodies; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Heart Failure; | 1995 |
Immunosuppressive treatment in autoreactive myocarditis--results from a controlled trial.
Topics: Acute Disease; Adult; Azathioprine; Drug Therapy, Combination; Female; Follow-Up Studies; Heart; Hum | 1994 |
Implications of the Myocarditis Treatment Trial for clinical practice.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Cyclosporine; Female; Follow-Up Studies; Huma | 1996 |
Immunopathogenesis and treatment of myocarditis: the United States Myocarditis Treatment Trial.
Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agen | 1996 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Immunosuppressive therapy in the management of acute myocarditis in children: a clinical trial.
Topics: Azathioprine; Biopsy; Child; Child, Preschool; Endocardium; Female; Humans; Immunosuppression Therap | 1991 |
Antiinflammatory effect of a lipoxygenase inhibitor (FLM 5011) in severe active myocarditis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Clinical Trials as Topic; Diclofenac; | 1988 |
56 other studies available for azathioprine and Carditis
| Article | Year |
|---|---|
Efficacy and safety of mycophenolate mofetil in patients with virus-negative lymphocytic myocarditis: A prospective cohort study.
Topics: Adult; Azathioprine; Cohort Studies; Female; Humans; Lymphocytes; Male; Middle Aged; Mycophenolic Ac | 2020 |
Immunosuppressive therapy in childhood-onset arrhythmogenic inflammatory cardiomyopathy.
Topics: Arrhythmogenic Right Ventricular Dysplasia; Azathioprine; Biomarkers; Child; Echocardiography; Elect | 2021 |
Morphologically proved ANCA positive Loeffler's pancarditis: medical and surgical treatment.
Topics: Adult; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Echocardiography; Electrocardiography; | 2019 |
Sustained improvement of cardiac function with immunosuppressive therapy in a case of acute lymphocytic myocarditis secondary to allopurinol induced Stevens-Johnson syndrome.
Topics: Adrenal Cortex Hormones; Aged; Allopurinol; Antimetabolites; Azathioprine; Drug Therapy, Combination | 2012 |
Silent myocarditis in myasthenia gravis. Role of cardiovascular magnetic resonance imaging.
Topics: Adult; Azathioprine; Cardiac Imaging Techniques; Echocardiography; Female; Humans; Immunosuppressive | 2016 |
A rare case of Behçet disease with generalised myositis, cardiomyositis and necrotising fasciitis.
Topics: Adult; Azathioprine; Behcet Syndrome; Fasciitis, Necrotizing; Female; Glucocorticoids; Humans; Immun | 2016 |
Prompt benefit of early immunosuppressive therapy in acute lymphocytic myocarditis with persistent heart failure.
Topics: Adult; Azathioprine; Biopsy; Drug Therapy, Combination; Female; Heart Failure; Humans; Immunosuppres | 2016 |
A Case of Thiopurine-Induced Acute Myocarditis in a Patient with Ulcerative Colitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atrial Fibrillation; Azathioprine; Cardiac Imaging Techniqu | 2016 |
[Effect of immune therapy in the prognosis of viral myocarditis in pediatric patients].
Topics: Adolescent; Antiviral Agents; Azathioprine; Child; Child, Preschool; Drug Therapy, Combination; Fema | 2016 |
The importance of serial cardiac troponin measurement for evaluating the response to immunosuppressive therapy for myocarditis.
Topics: Acute Disease; Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Myocarditis; Prednisolo | 2008 |
Hypersensitivity myocarditis associated with azithromycin exposure.
Topics: Anti-Bacterial Agents; Azathioprine; Azithromycin; Drug Hypersensitivity; Drug Therapy, Combination; | 2009 |
[Eosinophilic myopericarditis revealing a Churg-Strauss syndrome].
Topics: Azathioprine; Churg-Strauss Syndrome; Cyclophosphamide; Diagnosis, Differential; Drug Therapy, Combi | 2011 |
[Immunsuppressive therapy in virus-negative eosinophilic inflammatory cardiomyopathy].
Topics: Azathioprine; Biopsy; Cardiac Output, Low; Defibrillators, Implantable; Electrocardiography; Eosinop | 2011 |
Lone hepatitis C virus myocarditis responsive to immunosuppressive therapy.
Topics: Adult; Angiography; Azathioprine; Biopsy, Needle; Cohort Studies; Drug Administration Schedule; Elec | 2002 |
Immunosuppressive therapy for active lymphocytic myocarditis: virological and immunologic profile of responders versus nonresponders.
Topics: Adolescent; Adult; Autoantibodies; Azathioprine; Biopsy; Cardiotonic Agents; Chronic Disease; Echoca | 2003 |
ELECTROCARDIOGRAPHIC STUDIES IN HOMOLOGOUS CANINE HEART TRANSPLANTATIONS.
Topics: Animals; Azathioprine; Dogs; Electrocardiography; Heart; Heart Transplantation; Hydrocortisone; Kidn | 1965 |
Cell death, proliferation and repair in human myocarditis responding to immunosuppressive therapy.
Topics: Adolescent; Adult; Azathioprine; Cell Cycle Proteins; Cell Death; Cell Proliferation; DNA Repair; DN | 2006 |
Leukocytoclastic vasculitis with severe cardiac involvement in an infant: a case report.
Topics: Adrenal Cortex Hormones; Azathioprine; Catheterization; Extracorporeal Membrane Oxygenation; High-Fr | 2008 |
Diagnosis and management of acute myocarditis aided by serial myocardial biopsy.
Topics: Adult; Azathioprine; Biopsy; Drug Therapy, Combination; Echocardiography; Fluorescent Antibody Techn | 1984 |
Lymphocytic myocarditis presenting as unexplained ventricular arrhythmias: diagnosis with endomyocardial biopsy and response to immunosuppression.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Azathioprine; Biopsy; Cardiac Catheterization; Electr | 1984 |
Acute myocarditis. Role of histological and virological examination in the diagnosis and assessment of immunosuppressive treatment.
Topics: Acute Disease; Adolescent; Adult; Angiocardiography; Azathioprine; Drug Therapy, Combination; Female | 1984 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-1982. A 42-year-old woman with ulcerative colitis, dyspnea, and edema.
Topics: Adult; Azathioprine; Biopsy; Colitis, Ulcerative; Diagnosis, Differential; Female; Humans; Myocardit | 1982 |
Treatment of acute inflammatory myocarditis assisted by endomyocardial biopsy.
Topics: Acute Disease; Adolescent; Adult; Azathioprine; Biopsy; Humans; Inflammation; Male; Methylprednisolo | 1980 |
[Eosinophilic endomyocarditis post partum or pregnancy-related cardiomyopathy].
Topics: Adult; Azathioprine; Biopsy; Combined Modality Therapy; Cytomegalovirus Infections; Diagnosis, Diffe | 1994 |
Enterovirus-induced myocarditis: hemodynamic deterioration with immunosuppressive therapy and successful application of interferon-alpha.
Topics: Azathioprine; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Female; Hemo | 1994 |
[Comments on the contribution by M. Stille-Siegener et al. Myocarditis].
Topics: Azathioprine; Biopsy; Combined Modality Therapy; Drug Therapy, Combination; Endocardium; Humans; Myo | 1994 |
Heart transplantation for chronic Chagas' heart disease.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Cause of Death; Chagas Cardiomyopathy; Child; C | 1996 |
[Long-term observation of patients with biopsy proven myocarditis or dilated cardiomyopathy].
Topics: Adolescent; Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Drug Therapy, Combination; Echocar | 1996 |
Global biventricular dysfunction in patients with asymptomatic coronary artery disease may be caused by myocarditis.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Autoimmune Diseases; Azathioprine; Biopsy; Cardiomy | 1999 |
Histologically proven myocarditis in patients with biventricular dysfunction and severe asymptomatic coronary artery disease.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Biopsy; Coronary Angiography; Coronary Disease; Echoc | 1999 |
Combined immunosuppression for the treatment of idiopathic giant cell myocarditis.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Gian | 1999 |
Giant cell myocarditis responding to immunosuppressive therapy.
Topics: Adult; Azathioprine; Biopsy; Drug Administration Schedule; Drug Therapy, Combination; Endocardium; F | 2000 |
[Secondary immunologically-caused myocarditis, pericarditis and exudative pleuritis due to meningococcal meningitis].
Topics: Adolescent; Anti-Inflammatory Agents; Anticoagulants; Azathioprine; Diuretics, Osmotic; Echocardiogr | 2001 |
Autoimmune myocarditis: a clinical entity.
Topics: Adult; Autoimmune Diseases; Autopsy; Azathioprine; Biopsy; Complement C3; Dexamethasone; Humans; Imm | 1979 |
Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis.
Topics: Autoimmune Diseases; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy, Comb | 1992 |
Immunosuppressive therapy in inflammatory myocarditis: long-term follow-up.
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Endocardium; Female; Follow-Up Studies; He | 1992 |
Effects of immunosuppressive therapy in biopsy-proved myocarditis and borderline myocarditis on left ventricular function.
Topics: Adolescent; Adult; Aged; Azathioprine; Echocardiography; Female; Heart Failure; Hemodynamics; Humans | 1991 |
[Therapy and rehabilitation of patients with myocarditis].
Topics: Adult; Azathioprine; Biopsy; Cardiac Output; Dose-Response Relationship, Drug; Drug Administration S | 1991 |
Response of recurrent giant cell myocarditis in a transplanted heart to intensive immunosuppression.
Topics: Adult; Azathioprine; Biopsy; Cyclosporins; Granuloma, Giant Cell; Heart Failure; Heart Transplantati | 1991 |
[Immunosuppressive drugs for the treatment of active myocarditis in children. Hemodynamic evaluation].
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Cyclosporins; Drug Therapy, Combination; Female; | 1990 |
[Lymphocytic myocarditis. Response to treatment with immunosuppressive drugs].
Topics: Adolescent; Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Humans; Lymphoc | 1990 |
[Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy].
Topics: Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Cyclosporins; Drug Thera | 1990 |
"Borderline" myocarditis: an indication for repeat endomyocardial biopsy.
Topics: Azathioprine; Biopsy; Endocardium; Humans; Immunosuppressive Agents; Myocarditis; Myocardium; Predni | 1990 |
Peripartum myocarditis and cardiomyopathy.
Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Immunosuppression Therapy; Myocarditis | 1990 |
[Diagnosis and therapy of acute myocarditis].
Topics: Acute Disease; Adult; Azathioprine; Coronary Angiography; Echocardiography; Electrocardiography; Hum | 1990 |
[Late results of immunosuppressive therapy in patients with heart failure and biopsy proven myocarditis].
Topics: Adult; Azathioprine; Female; Follow-Up Studies; Heart Failure; Humans; Immunosuppressive Agents; Mal | 1989 |
Immunosuppressive treatment in myocarditis.
Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Female; Humans; Immunosuppressive Agents; Male; Middl | 1989 |
Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents.
Topics: Adult; Aged; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Male; Middle Aged; Myocarditis; | 1989 |
[Anti-Coxsackie antibodies and congestive cardiomyopathies].
Topics: Adult; Antibodies, Viral; Azathioprine; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovi | 1986 |
[Immunosuppressive treatment of chronic myocarditis].
Topics: Adolescent; Autoimmune Diseases; Azathioprine; Child; Child, Preschool; Chronic Disease; Drug Therap | 1988 |
Immunosuppressive therapy in the management of biopsy proven acute myocarditis.
Topics: Autoimmune Diseases; Azathioprine; Biopsy; Diagnosis, Differential; Drug Therapy, Combination; Hemod | 1985 |
Lack of objective improvement in ventricular systolic function in patients with myocarditis treated with azathioprine and prednisone.
Topics: Adult; Azathioprine; Female; Heart Ventricles; Humans; Immunosuppressive Agents; Male; Middle Aged; | 1985 |
[Experimental myocarditis in albino mice caused by influenza virus].
Topics: Animals; Azathioprine; Mice; Myocarditis; Myocardium; Orthomyxoviridae Infections | 1973 |
[Histologic study of orthotopic cardiac transplants in dogs].
Topics: Animals; Azathioprine; Dogs; Heart Transplantation; Myocarditis; Transplantation, Autologous; Transp | 1967 |
Myocardial changes and kidney transplantation. Lesions in patients receiving immunosuppressive therapy.
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Arteriosclerosis; Autopsy; Azathioprine; Candida; Car | 1969 |
[Therapy of idiopathic pulmonary hemosiderosis].
Topics: Adolescent; Azathioprine; Female; Hemosiderosis; Humans; Iron; Lung Diseases; Male; Myocarditis; Pre | 1971 |