Page last updated: 2024-10-23

azathioprine and Cardiovascular Stroke

azathioprine has been researched along with Cardiovascular Stroke in 19 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"To assess the risk of long-term cardiovascular and metabolic outcomes and all-cause mortality in patients with pemphigus managed by rituximab compared with those receiving treatment with first-line corticosteroid-sparing agents (azathioprine and mycophenolate mofetil [MMF])."4.31Association of Rituximab With Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients With Pemphigus. ( Kridin, K; Ludwig, RJ; Mruwat, N, 2023)
" Moreover, progressive renal insufficiency can develop as a result of the long-term use of this drug."1.29Immunosuppressive treatment in a heart transplantation candidate with antiphospholipid syndrome. ( Agostini, C; Biasiolo, A; De Silvestro, G; Livi, U; Marson, P; Pengo, V, 1996)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's2 (10.53)18.2507
2000's1 (5.26)29.6817
2010's1 (5.26)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Kridin, K3
Mruwat, N3
Ludwig, RJ3
Naser, W1
Lishner, M1
Choi, MY1
Li, D1
Feldman, CH1
Yoshida, K1
Guan, H1
Kim, SC1
Everett, BM1
Costenbader, KH1
Riis, JL1
Vestergaard, C1
Hjuler, KF1
Iversen, L1
Jakobsen, L1
Deleuran, MS1
Olsen, M1
Kotyla, PJ1
Sliwińska-Kotyla, B1
Lewicki, M1
Kucharz, EJ1
Fawwaz, RA1
Uberfuhr, P1
Reichart, B1
Welz, A1
Kreuzer, E1
Kemkes, BM1
Klinner, W1
Hammer, C1
Ertel, W1
Reichenspurner, H1
Gokel, M1
Land, W1
Franke, N1
Mathes, P1
Pengo, V1
Biasiolo, A1
Marson, P1
De Silvestro, G1
Agostini, C1
Livi, U1
Honoré, P1
Detry, O1
Meurisse, M1
Jacquet, N1
Moloney, P1
O'Brien, E1
Barnard, CN2
Degeorges, M1
Passa, P1
Varin, G1
Hulme, B1
Kenyon, JR1
Owen, K1
Snell, M1
Mowbray, JF1
Porter, KA1
Starkie, SJ1
Muras, H1
Peart, WS1
McNicol, GP1
Davies, JA1
Yao, JK1
Wilson, JK1
Casella, L1
Garvey, MB1
Douglas, FG1
Finlayson, DC1
Hart, JT1
Selby, DA1
Baker, CB1
Eales, L1
Grosser, Y1
Levey, M1
Dubost, C1
Cachera, JP1
Hewitt, J1
Escande, JP1
Leibowitch, M1
Franceschini, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Trial to Evaluate the Safety and Effectiveness of Normothermic Regional Perfusion (NRP) for Resuscitation of Hearts From Donation After Circulatory Death (DCD)[NCT04626284]10 participants (Actual)Interventional2021-01-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for azathioprine and Cardiovascular Stroke

ArticleYear
[Risk of atherosclerosis development in patients with systemic lupus erythematosus].
    Polskie Archiwum Medycyny Wewnetrznej, 2005, Volume: 114, Issue:5

    Topics: Adrenal Cortex Hormones; Arteriosclerosis; Autoantibodies; Azathioprine; Blood Coagulation Disorders

2005
Clinical utility of labeled cells for detection of allograft rejection and myocardial infarction.
    Seminars in nuclear medicine, 1984, Volume: 14, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Azathioprine; Blood Platelets; Cyclosporins; Graft Rejection; Heart

1984
Advances in medicine.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Anemia, Macrocytic; Anti-Arrhythmia Agents; Anticoagulants; Azathioprine; Chemical and Drug Induced

1972

Other Studies

16 other studies available for azathioprine and Cardiovascular Stroke

ArticleYear
Association of Rituximab With Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients With Pemphigus.
    JAMA dermatology, 2023, 01-01, Volume: 159, Issue:1

    Topics: Azathioprine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunosuppres

2023
Association of Rituximab With Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients With Pemphigus.
    JAMA dermatology, 2023, 01-01, Volume: 159, Issue:1

    Topics: Azathioprine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunosuppres

2023
Association of Rituximab With Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients With Pemphigus.
    JAMA dermatology, 2023, 01-01, Volume: 159, Issue:1

    Topics: Azathioprine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunosuppres

2023
Association of Rituximab With Risk of Long-term Cardiovascular and Metabolic Outcomes in Patients With Pemphigus.
    JAMA dermatology, 2023, 01-01, Volume: 159, Issue:1

    Topics: Azathioprine; Cohort Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunosuppres

2023
Behçet Disease Presenting as Acute Myocardial Infarction.
    The Israel Medical Association journal : IMAJ, 2020, Volume: 22, Issue:7

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Antimetabolites, Antineoplastic; Azathioprine; Behcet

2020
Comparative risks of cardiovascular disease events among SLE patients receiving immunosuppressive medications.
    Rheumatology (Oxford, England), 2021, 08-02, Volume: 60, Issue:8

    Topics: Adult; Azathioprine; Cardiovascular Diseases; Cause of Death; Coronary Artery Bypass; Cyclophosphami

2021
Hospital-diagnosed atopic dermatitis and long-term risk of myocardial infarction: a population-based follow-up study.
    BMJ open, 2016, 11-11, Volume: 6, Issue:11

    Topics: Adult; Aged; Ambulatory Care; Azathioprine; Case-Control Studies; Cyclosporine; Denmark; Dermatitis,

2016
[Report on a successful orthotopic cardiac transplantation in Germany].
    Klinische Wochenschrift, 1982, Dec-01, Volume: 60, Issue:23

    Topics: Adrenal Cortex Hormones; Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Cyclosporins; Dipyri

1982
Immunosuppressive treatment in a heart transplantation candidate with antiphospholipid syndrome.
    Clinical rheumatology, 1996, Volume: 15, Issue:5

    Topics: Adult; Antiphospholipid Syndrome; Azathioprine; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy,

1996
[Liver transplantation: experiences and results of a program at the University of Liege].
    Revue medicale de Liege, 1998, Volume: 53, Issue:12

    Topics: Actuarial Analysis; Acute Disease; Adrenal Cortex Hormones; Adult; Azathioprine; Belgium; Chronic Di

1998
Myocardial infarction and systemic lupus erythematosus: beneficial response to treatment with azathioprine.
    Irish journal of medical science, 1977, Volume: 146, Issue:12

    Topics: Adult; Azathioprine; Female; Humans; Lupus Erythematosus, Systemic; Myocardial Infarction

1977
The operation. A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1967, Dec-30, Volume: 41, Issue:48

    Topics: Azathioprine; Cobalt Isotopes; Dactinomycin; Heart Transplantation; Humans; Hydrocortisone; Male; Me

1967
Human heart transplantation.
    Canadian Medical Association journal, 1969, Jan-18, Volume: 100, Issue:3

    Topics: Antibodies, Anti-Idiotypic; Azathioprine; Cardiac Catheterization; Cardiac Output; Cardiomegaly; Car

1969
[Dressler's syndrome relapsing during corticotherapy but cured with immunosuppressive agents].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1972, Mar-14, Volume: 48, Issue:13

    Topics: Azathioprine; Humans; Indomethacin; Male; Middle Aged; Myocardial Infarction; Pericarditis; Pleurisy

1972
Renal transplantation in children. Analysis of 25 consecutive transplants in 19 recipients.
    Archives of disease in childhood, 1972, Volume: 47, Issue:254

    Topics: Adolescent; Azathioprine; Child; Female; Graft Rejection; Histocompatibility Testing; Humans; Immuno

1972
Human heart transplantation: report of a case.
    Canadian Medical Association journal, 1969, Oct-18, Volume: 101, Issue:8

    Topics: Antilymphocyte Serum; Azathioprine; Electrocardiography; Heart Transplantation; Hemodynamics; Histoc

1969
Coproporphyrinuria and heart transplantation: its significance.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Sep-12, Volume: 44, Issue:36

    Topics: Age Factors; Anemia, Hemolytic; Azathioprine; Chemical and Drug Induced Liver Injury; Electrocardiog

1970
[3 cases of allogenic heart graft in man].
    Archives des maladies du coeur et des vaisseaux, 1969, Volume: 62, Issue:6

    Topics: Adult; Angiocardiography; Azathioprine; Coronary Disease; Electrocardiography; Globulins; Heart Fail

1969
[Trial therapy of psoriasis with azathioprine].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:3

    Topics: Adult; Aged; Anemia; Azathioprine; Female; Humans; Leukopenia; Male; Middle Aged; Myocardial Infarct

1970