azathioprine has been researched along with Cardiomyopathy, Dilated in 29 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the second postoperative week, while being treated with monoclonal antibodies (OKT3), cyclosporine and azathioprine, he developed a postpericardiotomy syndrome and cardiac tamponade, which necessitated emergency pericardiocentesis." | 3.70 | Postpericardiotomy syndrome during intensive immunosuppression after cardiac transplantation. ( Charitos, CE; Kontoyannis, DA; Nanas, JN, 2000) |
| "The immunosuppressive therapy with azathioprine or cyclosporine plus prednisone leads to decrease of active myocarditis intensity in a higher proportion of cases than the treatment with only prednisone or no immunosuppressive drugs." | 3.68 | [Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy]. ( Aiello, VD; Camargo, PR; Ebaid, M; Fiorelli, A; Higuchi, Mde L; Mazzieri, R; Pileggi, F; Snitcowsky, R, 1990) |
| "Thirty-four patients with history of congestive heart failure, dilated cardiomyopathy, and biopsy-proven lymphocytic myocarditis were treated for six months with immunosuppressive agents (prednisone and azathioprine) in addition to standard therapy for congestive heart failure." | 3.67 | Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents. ( Badhwar, K; Bott-Silverman, C; Hobbs, RE; Pelegrin, D; Ratliff, NB; Rincon, G; Sterba, R, 1989) |
| "Of 202 patients with dilated cardiomyopathy, 84 patients with increased HLA expression were randomized to receive either immunosuppression or placebo for 3 months; they were then followed for 2 years." | 2.70 | Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results. ( Glanowska, G; Niklewski, T; Nowalany-Kozielska, E; Polonski, L; Rozek, MM; Wilczewski, P; Wodniecki, J; Wojciechowska, C; Wojnicz, R; Zembala, M, 2001) |
| "He was diagnosed with dilated cardiomyopathy and MD complicating LSVA in TA based on combined clinical and pathognomonic diagnostic criteria of TA evaluated using vascular Doppler and computed tomography angiography of the aorta." | 1.62 | Myocardial dissection complicating left sinus of Valsalva aneurysm in silent takayasu arteritis. ( Astuti, A; Fahlavi, MD; Hamijoyo, L; Hasan, M; Ilhamy, MA; Kartamihardja, AHA; Kusumawardhani, NY, 2021) |
| "Prednisolone dosage was reduced and cyclosporin (350 mg/d) substituted for azathioprine." | 1.30 | [Late manifestation of a fatal Behçet's disease with cardiac involvement and lethal outcome]. ( Bocker, T; Görnig, M; Kaatz, M; Wollina, U; Zouboulis, CC, 1998) |
| "In 1985, myocarditis was diagnosed by endomyocardial biopsy in a 53-year-old woman who was free of symptoms of heart insufficiency." | 1.29 | Enterovirus-induced myocarditis: hemodynamic deterioration with immunosuppressive therapy and successful application of interferon-alpha. ( Figulla, HR; Heim, A; Kandolf, R; Kreuzer, H; Stille-Siegener, M, 1994) |
| " Moreover, progressive renal insufficiency can develop as a result of the long-term use of this drug." | 1.29 | Immunosuppressive treatment in a heart transplantation candidate with antiphospholipid syndrome. ( Agostini, C; Biasiolo, A; De Silvestro, G; Livi, U; Marson, P; Pengo, V, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 14 (48.28) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Astuti, A | 1 |
| Kartamihardja, AHA | 1 |
| Ilhamy, MA | 1 |
| Fahlavi, MD | 1 |
| Kusumawardhani, NY | 1 |
| Hasan, M | 1 |
| Hamijoyo, L | 1 |
| De Luca, G | 1 |
| Campochiaro, C | 1 |
| Sartorelli, S | 1 |
| Peretto, G | 1 |
| Dagna, L | 1 |
| Mahdavi, M | 1 |
| Hejri, GM | 1 |
| Hia, CP | 1 |
| Yip, WC | 1 |
| Tai, BC | 1 |
| Quek, SC | 1 |
| Dorschner, L | 1 |
| Speich, R | 1 |
| Ruschitzka, F | 1 |
| Seebach, JD | 1 |
| Gallino, A | 1 |
| Schmid, C | 1 |
| Schneider, M | 1 |
| Etz, C | 1 |
| Scheld, HH | 1 |
| Annemans, L | 1 |
| Lemkuhl, H | 1 |
| Tenderich, G | 1 |
| Schulz, U | 1 |
| Yang, XL | 1 |
| Ricci, JF | 1 |
| Hetzer, R | 1 |
| Beitzke, A | 1 |
| Suppan, C | 1 |
| Trittenwein, G | 1 |
| Heim, A | 1 |
| Stille-Siegener, M | 1 |
| Kandolf, R | 1 |
| Kreuzer, H | 1 |
| Figulla, HR | 1 |
| Ahner, R | 1 |
| Kiss, H | 1 |
| Zuckermann, A | 1 |
| Pengo, V | 1 |
| Biasiolo, A | 1 |
| Marson, P | 1 |
| De Silvestro, G | 1 |
| Agostini, C | 1 |
| Livi, U | 1 |
| Olszowska, M | 1 |
| Tracz, W | 1 |
| Kokoszka, M | 1 |
| Pieniazek, P | 1 |
| Przewłocki, T | 1 |
| Hlawaty, M | 1 |
| Podolec, P | 1 |
| Frasik, W | 1 |
| Lazar, A | 1 |
| Dziatkowiak, A | 1 |
| Ishizuka, N | 1 |
| Nakamura, K | 1 |
| Fujita, Y | 1 |
| Tanimoto, K | 1 |
| Niki, K | 1 |
| Hosoda, S | 1 |
| Hachida, M | 1 |
| Koyanagi, H | 1 |
| Chawalit, O | 1 |
| Meunmai, S | 1 |
| Kittichai, L | 1 |
| Suchit, B | 1 |
| Somchai, W | 1 |
| Chompunoot, O | 1 |
| Kurtpoom, M | 1 |
| Karoonpan, S | 1 |
| Pawong, S | 1 |
| Peerapong, S | 1 |
| Kaatz, M | 1 |
| Görnig, M | 1 |
| Bocker, T | 1 |
| Zouboulis, CC | 1 |
| Wollina, U | 1 |
| Morini, A | 1 |
| Spina, V | 1 |
| Aleandri, V | 1 |
| Cantonetti, G | 1 |
| Lambiasi, A | 1 |
| Papalia, U | 1 |
| Ko, WJ | 1 |
| Chou, NK | 1 |
| Chen, YS | 1 |
| Hsu, RB | 1 |
| Wang, SS | 1 |
| Chu, SH | 1 |
| Frustaci, A | 1 |
| Chimenti, C | 1 |
| Maseri, A | 1 |
| Sánchez, V | 1 |
| Delgado, JF | 1 |
| Blasco, T | 1 |
| Dalmau, R | 1 |
| Morales, JM | 1 |
| Escribano, P | 1 |
| Tello, R | 1 |
| Hernández, J | 1 |
| Velázquez, T | 1 |
| Sotelo, T | 1 |
| Gómez-Sánchez, MA | 1 |
| Sáenz de la Calzada, C | 1 |
| Charitos, CE | 1 |
| Kontoyannis, DA | 1 |
| Nanas, JN | 1 |
| Wojnicz, R | 1 |
| Nowalany-Kozielska, E | 1 |
| Wojciechowska, C | 1 |
| Glanowska, G | 1 |
| Wilczewski, P | 1 |
| Niklewski, T | 1 |
| Zembala, M | 1 |
| Polonski, L | 1 |
| Rozek, MM | 1 |
| Wodniecki, J | 1 |
| Desjardins, V | 1 |
| Pelletier, G | 1 |
| Leung, TK | 1 |
| Waters, D | 1 |
| Arteaga-Fernánez, E | 1 |
| Barretto, AC | 1 |
| Mady, C | 1 |
| Higuchi, ML | 1 |
| Fiorelli, AI | 1 |
| Bellotti, G | 1 |
| Jatene, AD | 1 |
| Pileggi, F | 2 |
| Higuchi, Mde L | 1 |
| Camargo, PR | 1 |
| Aiello, VD | 1 |
| Mazzieri, R | 1 |
| Snitcowsky, R | 1 |
| Fiorelli, A | 1 |
| Ebaid, M | 1 |
| Midei, MG | 1 |
| DeMent, SH | 1 |
| Feldman, AM | 1 |
| Hutchins, GM | 1 |
| Baughman, KL | 1 |
| Aravot, DJ | 1 |
| Banner, NR | 1 |
| Khaghani, A | 1 |
| Fitzgerald, M | 1 |
| Radley-Smith, R | 1 |
| Mitchell, AG | 1 |
| Yacoub, MH | 1 |
| Hobbs, RE | 1 |
| Pelegrin, D | 1 |
| Ratliff, NB | 1 |
| Bott-Silverman, C | 1 |
| Rincon, G | 1 |
| Sterba, R | 1 |
| Badhwar, K | 1 |
| Leroy, O | 1 |
| Asseman, P | 1 |
| Traisnel, G | 1 |
| Durand, P | 1 |
| Beuscart, R | 1 |
| Dewilde, A | 1 |
| Wattré, P | 1 |
| Théry, C | 1 |
| Amuchástegui, M | 1 |
| Madoery, R | 1 |
| Noguera, E | 1 |
| Mothe, G | 1 |
| Amuchástegui, LM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| RANDOMIZED, MULTICENTRIC STUDY COMPARING THE EFFECT OF TWO REGIMENS OF COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE TREATMENT OF INFLAMMATORY CARDIOMYOPATHY CZECH-ICIT (CZECH INFLAMMATORY CARDIOMYOPATHY IMMUNOSUPPRESSION TRIAL)[NCT01877746] | Phase 3 | 234 participants (Anticipated) | Interventional | 2013-01-31 | Recruiting | ||
| Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry[NCT05158751] | 100 participants (Anticipated) | Observational | 2023-01-31 | Not yet recruiting | |||
| Prospective, Observational Trial of Biological or Prosthetic Mesh for Open Ventral Hernia Repair[NCT03317665] | 28 participants (Actual) | Observational | 2019-02-11 | Terminated (stopped due to Premature termination due to cease of funding) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Therapeutic strategies for virus-negative myocarditis: a comprehensive review.
Topics: Azathioprine; Cardiomyopathy, Dilated; Humans; Immunosuppressive Agents; Myocarditis; Myocardium | 2020 |
Immunosuppressive therapy in acute myocarditis: an 18 year systematic review.
Topics: Acute Disease; Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Female; H | 2004 |
Pregnancy after heart transplant: update and case report.
Topics: Adult; Azathioprine; Blood Pressure; Cardiomyopathy, Dilated; Cesarean Section; Cyclosporine; Female | 1998 |
3 trials available for azathioprine and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation.
Topics: Acute Disease; Adult; Azathioprine; Belgium; Cardiomyopathy, Dilated; Coronary Disease; Cost of Illn | 2007 |
Clinical trial of FK506 in heart transplant patients in Taiwan: report of 7 cases with immunosuppression switch from cyclosporine to FK506.
Topics: Adult; Aged; Azathioprine; Cardiomyopathy, Dilated; Child; Cyclosporine; Drug Therapy, Combination; | 1998 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
Randomized, placebo-controlled study for immunosuppressive treatment of inflammatory dilated cardiomyopathy: two-year follow-up results.
Topics: Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Chronic Disease; Drug Therapy, Combination; En | 2001 |
23 other studies available for azathioprine and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Myocardial dissection complicating left sinus of Valsalva aneurysm in silent takayasu arteritis.
Topics: Adult; Aortic Aneurysm; Aortic Dissection; Azathioprine; Cardiomyopathy, Dilated; Humans; Immunosupp | 2021 |
Oral Ulcerations Induced by Mycophenolate Mofetil Following Cardiac Transplant.
Topics: Azathioprine; Cardiomyopathy, Dilated; Drug Substitution; Graft Rejection; Graft Survival; Heart Tra | 2016 |
Everolimus-induced drug fever after heart transplantation.
Topics: Aged; Azathioprine; Cardiomyopathy, Dilated; Drug Therapy, Combination; Everolimus; Fever; Heart Tra | 2004 |
Heart transplantation in a patient with a left ventricular assist device and methicillin-resistant Staphylococcus aureus infection.
Topics: Adolescent; Azathioprine; Cardiomyopathy, Dilated; Cyclosporine; Equipment Contamination; Heart Tran | 2004 |
[Immunosuppressive therapy in congestive cardiomyopathy in childhood].
Topics: Adolescent; Autoantibodies; Autoimmune Diseases; Azathioprine; Cardiomyopathy, Dilated; Child; Elect | 1984 |
Enterovirus-induced myocarditis: hemodynamic deterioration with immunosuppressive therapy and successful application of interferon-alpha.
Topics: Azathioprine; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovirus B, Human; Female; Hemo | 1994 |
[Pregnancy and spontaneous delivery 13 months after heart transplantation].
Topics: Azathioprine; Cardiomyopathy, Dilated; Cyclosporine; Dose-Response Relationship, Drug; Echocardiogra | 1993 |
Immunosuppressive treatment in a heart transplantation candidate with antiphospholipid syndrome.
Topics: Adult; Antiphospholipid Syndrome; Azathioprine; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy, | 1996 |
[Long-term observation of patients with biopsy proven myocarditis or dilated cardiomyopathy].
Topics: Adolescent; Adult; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Drug Therapy, Combination; Echocar | 1996 |
[Transesophageal echocardiographic findings in patients after heart transplantation].
Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Cyclosporine; Echocardiography, Doppler, Color; Echoca | 1997 |
The first successful heart transplantation in South East Asia.
Topics: Adult; Azathioprine; Brain Death; Cardiomyopathy, Dilated; Cyclosporine; Female; Follow-Up Studies; | 1988 |
[Late manifestation of a fatal Behçet's disease with cardiac involvement and lethal outcome].
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Behcet Syndrome; Cardiomyopathy, Dilated; Cyclosporine | 1998 |
Global biventricular dysfunction in patients with asymptomatic coronary artery disease may be caused by myocarditis.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Autoimmune Diseases; Azathioprine; Biopsy; Cardiomy | 1999 |
Benefits of mycophenolate mofetil in cardiac transplant recipients with cyclosporine-induced nephropathy.
Topics: Azathioprine; Cardiomyopathy, Dilated; Coronary Disease; Cyclosporine; Female; Graft Rejection; Hear | 1999 |
Postpericardiotomy syndrome during intensive immunosuppression after cardiac transplantation.
Topics: Adolescent; Azathioprine; Cardiac Tamponade; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy, Co | 2000 |
Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis.
Topics: Autoimmune Diseases; Azathioprine; Biopsy; Cardiomyopathy, Dilated; Cyclosporine; Drug Therapy, Comb | 1992 |
[Lymphocytic myocarditis. Response to treatment with immunosuppressive drugs].
Topics: Adolescent; Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Follow-Up Studies; Humans; Lymphoc | 1990 |
[Histologic response of the myocardium to various immunosuppressor schedules in patients with dilated cardiomyopathy and diagnosis of myocarditis at endomyocardial biopsy].
Topics: Adolescent; Azathioprine; Cardiomyopathy, Dilated; Child; Child, Preschool; Cyclosporins; Drug Thera | 1990 |
Peripartum myocarditis and cardiomyopathy.
Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Immunosuppression Therapy; Myocarditis | 1990 |
Cardiac transplantation in the seventh decade of life.
Topics: Actuarial Analysis; Aged; Azathioprine; Cardiomyopathy, Dilated; Coronary Disease; Cyclosporins; Fem | 1989 |
Lymphocytic myocarditis and dilated cardiomyopathy: treatment with immunosuppressive agents.
Topics: Adult; Aged; Azathioprine; Cardiomyopathy, Dilated; Female; Humans; Male; Middle Aged; Myocarditis; | 1989 |
[Anti-Coxsackie antibodies and congestive cardiomyopathies].
Topics: Adult; Antibodies, Viral; Azathioprine; Cardiomyopathy, Dilated; Coxsackievirus Infections; Enterovi | 1986 |
[Cardiac scintigraphy with gallium 67: an alternative in the treatment of dilated cardiomyopathy].
Topics: Adult; Azathioprine; Cardiomyopathy, Dilated; Echocardiography; Gallium Radioisotopes; Humans; Male; | 1987 |