Page last updated: 2024-10-23

azathioprine and Carcinoma

azathioprine has been researched along with Carcinoma in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
" Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation."3.70Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998)
"No significant risk for other intestinal cancers was found, especially for small bowel carcinoma."1.43Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016)
"Azathioprine was administered to 25 patients with severe, progressive polyarthritis in a mean dose of 1."1.26Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients. ( Pinals, RS, 1976)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheddani, H1
Dauchet, L1
Fumery, M1
Charpentier, C1
Marie Bouvier, A1
Dupas, JL1
Pariente, B1
Peyrin-Biroulet, L1
Savoye, G1
Gower-Rousseau, C1
Lakatos, L1
Lakatos, PL1
Paracchini, ML1
Rocchini, GM1
Renoldi, P1
Fiorini, GF1
Gosso, P1
Onida, L1
Geniram, A1
Marini, U1
Gibelli, A1
Campo, MS1
O'Neil, BW1
Barron, RJ1
Jarrett, WF1
Schmidt, S1
Padberg, F1
Rogers, AI1
Mitrou, PS1
Fischer, M1
Mitrou, G1
Röttger, P1
Pinals, RS1
Melosky, B1
Karim, M1
Chui, A1
McBride, M1
Cameron, EC1
Yeung, CK1
Landsberg, D1
Shackleton, C1
Keown, PA1
Zelig, MP1
Choi, PM1
Birkeland, SA1
Kemp, E1
Dargent, M1
Bourgoin, JJ1
Noel, P1
Weissbrod, R1
Patterson, JF1
Norton, RA1
Schwartz, RS1
Gerhartz, H1

Reviews

2 reviews available for azathioprine and Carcinoma

ArticleYear
[Medical therapy of inflammatory bowel diseases: ulcerative colitis].
    Orvosi hetilap, 2007, Jun-24, Volume: 148, Issue:25

    Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies,

2007
Lymphoproliferative disorders after renal transplantation in patients receiving triple or quadruple immunosuppression.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:12 Suppl

    Topics: Actuarial Analysis; Antilymphocyte Serum; Azathioprine; Carcinoma; Cyclosporine; Graft Survival; Her

1992

Other Studies

13 other studies available for azathioprine and Carcinoma

ArticleYear
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:10

    Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi

2016
Acquired factor VIII inhibitor in a non-haemophilic patient: successful treatment with plasma exchange associated with factor VIII concentrate and immunosuppressors.
    Haemostasis, 1984, Volume: 14, Issue:3

    Topics: Autoantibodies; Azathioprine; Carcinoma; Combined Modality Therapy; Common Bile Duct Neoplasms; Fact

1984
Experimental reproduction of the papilloma-carcinoma complex of the alimentary canal in cattle.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: Animals; Azathioprine; Bovine papillomavirus 1; Bovine papillomavirus 4; Carcinoma; Cattle; Cattle D

1994
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
    Journal of the neurological sciences, 1998, May-07, Volume: 157, Issue:2

    Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic

1998
Managing ulcerative colitis.
    Comprehensive therapy, 1976, Volume: 2, Issue:6

    Topics: Azathioprine; Carcinoma; Colitis, Ulcerative; Colonic Neoplasms; Humans; Prednisone; Sulfasalazine

1976
The oncogenic effect of immunosuppressive (cytotoxic) agents in (NZB x NZW) mice. II. Emergence of tumors in young animals treated with azathioprine and ifosfamide, including a histologic assessment of the neoplasms.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:4

    Topics: Animals; Azathioprine; Carcinogens; Carcinoma; Cyclophosphamide; Female; Hyperplasia; Ifosfamide; Ly

1979
Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients.
    The Journal of rheumatology, 1976, Volume: 3, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Carcinoma; Femal

1976
Azathioprine or 6-mercaptopurine therapy and colon carcinoma in Crohn's disease.
    Gastroenterology, 1992, Volume: 102, Issue:4 Pt 1

    Topics: Adult; Azathioprine; Carcinoma; Colonic Neoplasms; Crohn Disease; Humans; Mercaptopurine

1992
Treatment of myasthenia--I.
    British medical journal, 1971, Apr-17, Volume: 2, Issue:5754

    Topics: Adrenocorticotropic Hormone; Azathioprine; Bronchial Neoplasms; Carcinoma; Cholinesterase Inhibitors

1971
Malignant tumours following immunosuppression in renal transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom

1973
The influence of azathioprine on tumorogenesis by 7-12 dimethylbenz (a) anthracene in rats.
    European journal of cancer, 1972, Volume: 8, Issue:6

    Topics: Adenocarcinoma; Adenofibroma; Animals; Azathioprine; Benz(a)Anthracenes; Carcinoma; Female; Fibroma;

1972
Azathioprine treatment of ulcerative colitis, granulomatous colitis and regional enteritis.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Carcinoma; Colectomy; Colitis, Ulcerative; Colonic Neoplasms;

1971
[Fundamentals of clinical chemotherapy].
    Deutsches medizinisches Journal, 1968, Mar-05, Volume: 19, Issue:5

    Topics: Antineoplastic Agents; Azathioprine; Carcinoma; Cyclophosphamide; Humans; Neoplasm Metastasis; Sarco

1968