azathioprine has been researched along with Carcinoma in Situ in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Carcinoma in Situ: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the risk of acquiring skin cancer increases with the length of immunosuppressive therapy." | 2.67 | No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective. ( Blohmé, I; Larkö, O, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, AC | 1 |
| Warnakulasuriya, S | 1 |
| Thompson, RP | 1 |
| Amato, MP | 1 |
| Pracucci, G | 1 |
| Ponziani, G | 1 |
| Siracusa, G | 1 |
| Fratiglioni, L | 1 |
| Amaducci, L | 1 |
| Volgger, B | 1 |
| Marth, C | 1 |
| Zeimet, A | 1 |
| Müller-Holzner, E | 1 |
| Ruth, N | 1 |
| Dapunt, O | 1 |
| Leckie, GB | 1 |
| Cotton, RE | 1 |
| Norfleet, RG | 1 |
| Sampson, CE | 1 |
| Blohmé, I | 1 |
| Larkö, O | 1 |
| Reeve, VE | 1 |
| Greenoak, GE | 1 |
| Gallagher, CH | 1 |
| Canfield, PJ | 1 |
| Wilkinson, FJ | 1 |
| Donohue, LR | 1 |
1 review available for azathioprine and Carcinoma in Situ
| Article | Year |
|---|---|
Colposcopic and cytologic evaluation of women undergoing immunosuppressive therapy.
Topics: Antigens, Neoplasm; Azathioprine; Carcinoma in Situ; Carcinoma, Squamous Cell; Colposcopy; Female; G | 1974 |
1 trial available for azathioprine and Carcinoma in Situ
| Article | Year |
|---|---|
No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective.
Topics: Azathioprine; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Foll | 1992 |
6 other studies available for azathioprine and Carcinoma in Situ
| Article | Year |
|---|---|
Neoplasia of the tongue in a patient with Crohn's disease treated with azathioprine: case report.
Topics: Adult; Antimetabolites; Azathioprine; Carcinoma in Situ; Crohn Disease; Humans; Male; Mouth Mucosa; | 2003 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
Fulminant course of a microinvasive vulvar carcinoma in an immunosuppressed woman.
Topics: Adult; Azathioprine; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Condylomata Acuminata | 1997 |
Simultaneous in situ carcinoma of the cervix, vulva and perineum after immunosuppressive therapy for renal transplantation.
Topics: Adult; Azathioprine; Carcinoma in Situ; Female; Humans; Immunosuppression Therapy; Kidney Transplant | 1977 |
Carcinoma of the cervix after treatment with prednisone and azathioprine for chronic active hepatitis.
Topics: Adult; Azathioprine; Carcinoma in Situ; Chronic Disease; Female; Hepatitis; Humans; Immunosuppressio | 1978 |
Effect of immunosuppressive agents and sunscreens on UV carcinogenesis in the hairless mouse.
Topics: 4-Aminobenzoic Acid; Animals; Antibody Formation; Azathioprine; Carcinoma in Situ; Carcinoma, Squamo | 1985 |