azathioprine has been researched along with Carcinoma, Thymic in 36 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 7.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 3.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| " Under immunosuppressive treatment with azathioprine and steroids, the patient developed cytomegalovirus (CMV) enteritis which was triggered by therapy-induced leukopenia." | 3.75 | [A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection]. ( Baba, HA; Gerken, G; Kahraman, A; Maldonado-Lopez, E; Miller, M; Treichel, U, 2009) |
| " Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation." | 3.70 | Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998) |
| "6 years after resection and postirradiation of an "asymptomatic" thymoma, myasthenia gravis developed in a 46 year old man which improved within 6 months following initiation of immunosuppressive therapy with azathioprine." | 3.65 | [Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)]. ( Fischer, K; Janzen, RW; Lachenmayer, L, 1977) |
| "Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production." | 2.41 | [A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy]. ( Inoue, Y; Matsuda, O; Takahashi, K; Takemura, T; Yoshimura, A, 2000) |
| "Limbic encephalitis is typically characterised by a sub-acute onset of disorientation, amnesia and seizures, but the clinical spectrum is not yet fully defined and the syndrome could be under-diagnosed." | 1.35 | Hypothermia in VGKC antibody-associated limbic encephalitis. ( Clover, L; Grubneac, A; Irani, SR; Jacob, S; Rajabally, YA; Vincent, A; Walters, RJ; Yazaki, M, 2008) |
| "Only four patients with extrathymic tumors had an associated thymoma." | 1.33 | Extrathymic malignancies in patients with myasthenia gravis. ( Abramsky, O; Argov, Z; Ben Hur, T; Karussis, D; Levin, N; Lossos, A; Siegal, T, 2005) |
| " Remission, pharmacological remission, and marked improvement with reduction in drug dosage were considered good results." | 1.31 | Clinical characteristics and prognosis of myasthenia gravis in older people. ( Batocchi, AP; Di Schino, C; Evoli, A; Minisci, C; Tonali, P, 2000) |
| "Thymoma was more common in the older population; these patients did no worse than the population as a whole." | 1.28 | The relationship of age to outcome in myasthenia gravis. ( Ansher, M; Donaldson, DH; Horan, S; Ringel, SP; Rutherford, RB, 1990) |
| "The thymoma was removed: after the operation no improvement of her anaemic condition was observed and colony growth was very poor, although T-depleted narrow preparations showed a modest BFU-E formation in autologous serum." | 1.27 | Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment. ( Dalton, R; Eridani, S; Sawyer, B; Whitehead, S, 1986) |
| "A group of 16 patients with severe generalized myasthenia gravis (MG) (five with thymoma) that was resistant to anticholinesterases, thymectomy, and corticosteroids were treated by plasmapheresis." | 1.26 | Plasmapheresis in refractory generalized myasthenia gravis. ( Ambinder, EP; Bender, AN; Genkins, G; Goldberg, J; Kornfeld, P; Mittag, T; Papatestas, AE, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (44.44) | 18.7374 |
| 1990's | 8 (22.22) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 4 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, EG | 1 |
| Pottegård, A | 1 |
| Hallas, J | 1 |
| Friis, S | 1 |
| Hansen, K | 1 |
| Jensen, PE | 1 |
| Gaist, D | 1 |
| Benjamin, B | 1 |
| Zaltzman, R | 1 |
| Shpitz, B | 1 |
| Gordon, CR | 1 |
| Avital, S | 1 |
| Modrego, PJ | 1 |
| Arribas, J | 1 |
| Kahraman, A | 1 |
| Miller, M | 1 |
| Maldonado-Lopez, E | 1 |
| Baba, HA | 1 |
| Treichel, U | 1 |
| Gerken, G | 1 |
| Rigamonti, A | 1 |
| Lauria, G | 1 |
| Piamarta, F | 1 |
| Fiumani, A | 1 |
| Agostoni, E | 1 |
| Gogovska, L | 1 |
| Ljapcev, R | 1 |
| Polenakovic, M | 1 |
| Stojkovski, L | 1 |
| Popovska, M | 1 |
| Grcevska, L | 1 |
| Romi, F | 1 |
| Gilhus, NE | 1 |
| Varhaug, JE | 1 |
| Myking, A | 1 |
| Aarli, JA | 1 |
| Levin, N | 1 |
| Abramsky, O | 1 |
| Lossos, A | 1 |
| Karussis, D | 1 |
| Siegal, T | 1 |
| Argov, Z | 1 |
| Ben Hur, T | 1 |
| Ashraf, VV | 1 |
| Taly, AB | 1 |
| Veerendrakumar, M | 1 |
| Rao, S | 1 |
| Jacob, S | 1 |
| Irani, SR | 1 |
| Rajabally, YA | 1 |
| Grubneac, A | 1 |
| Walters, RJ | 1 |
| Yazaki, M | 1 |
| Clover, L | 1 |
| Vincent, A | 1 |
| Schumm, F | 1 |
| Brinkmann, A | 1 |
| Fateh-Moghadam, A | 1 |
| Dau, PC | 1 |
| Kornfeld, P | 1 |
| Ambinder, EP | 1 |
| Mittag, T | 1 |
| Bender, AN | 1 |
| Papatestas, AE | 1 |
| Goldberg, J | 1 |
| Genkins, G | 1 |
| Mukaida, T | 1 |
| Aoe, M | 1 |
| Yamashita, M | 1 |
| Date, H | 1 |
| Ando, A | 1 |
| Shimizu, N | 1 |
| Beekman, R | 1 |
| Kuks, JB | 1 |
| Oosterhuis, HJ | 1 |
| Schmidt, S | 1 |
| Padberg, F | 1 |
| Crawford, WW | 1 |
| Yusin, JS | 1 |
| Klaustermeyer, WB | 1 |
| Takahashi, K | 1 |
| Inoue, Y | 1 |
| Matsuda, O | 1 |
| Takemura, T | 1 |
| Yoshimura, A | 1 |
| Evoli, A | 1 |
| Batocchi, AP | 1 |
| Minisci, C | 1 |
| Di Schino, C | 1 |
| Tonali, P | 1 |
| Janzen, RW | 1 |
| Lachenmayer, L | 1 |
| Fischer, K | 1 |
| Arimori, S | 1 |
| Nakata, Y | 1 |
| Tada, S | 1 |
| Kobashi, H | 1 |
| Koriyama, K | 1 |
| Ichikawa, Y | 1 |
| Mitsuhashi, A | 1 |
| Iwasaki, I | 1 |
| Hiraki, K | 1 |
| Zimmermann, CW | 1 |
| Lingenfelser, T | 1 |
| Melms, A | 1 |
| Jakober, B | 1 |
| Kumagai, M | 1 |
| Kondou, T | 1 |
| Handa, M | 1 |
| Shiraishi, Y | 1 |
| Fujimura, S | 1 |
| Nakata, T | 1 |
| Mathieson, PW | 1 |
| O'Neill, JH | 1 |
| Durrant, ST | 1 |
| Henderson, SJ | 1 |
| Green, PJ | 1 |
| Newsom-Davis, J | 1 |
| Donaldson, DH | 1 |
| Ansher, M | 1 |
| Horan, S | 1 |
| Rutherford, RB | 1 |
| Ringel, SP | 1 |
| Smith, N | 1 |
| Boughton, BJ | 1 |
| Eridani, S | 1 |
| Whitehead, S | 1 |
| Sawyer, B | 1 |
| Dalton, R | 1 |
| Herrmann, C | 1 |
| Lindstrom, JM | 1 |
| Keesey, JC | 1 |
| Mulder, DG | 1 |
| Meier, H | 1 |
| Fox, RR | 1 |
| Casey, TP | 2 |
| Ricken, D | 1 |
| Marmont, A | 1 |
| Gori, E | 1 |
| Doll, R | 1 |
| Kinlen, L | 1 |
| Böttcher, D | 1 |
| Maas, D | 1 |
| Wendt, F | 1 |
| Schubothe, H | 1 |
| Safdar, SH | 1 |
| Krantz, SB | 1 |
| Brown, EB | 1 |
2 reviews available for azathioprine and Carcinoma, Thymic
| Article | Year |
|---|---|
[A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy].
Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Middle Aged; Myasthenia Gravis; Nephrosis, L | 2000 |
Myasthenia gravis--current concepts.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Autoimmune Diseases; Azathio | 1985 |
34 other studies available for azathioprine and Carcinoma, Thymic
| Article | Year |
|---|---|
Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark.
Topics: Aged; Aged, 80 and over; Azathioprine; Case-Control Studies; Denmark; Female; Humans; Male; Middle A | 2013 |
Presacral Mass Discovered during Pregnancy followed by Myasthenia Gravis.
Topics: Adult; Azathioprine; Castleman Disease; Cholinesterase Inhibitors; Female; Humans; Immunosuppressive | 2015 |
Spontaneous resolution of a mediastinal mass in a woman with myasthenia gravis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azathioprine; Cholinesterase Inhib | 2018 |
[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection].
Topics: Agammaglobulinemia; Antiviral Agents; Azathioprine; Cidofovir; Colitis, Ulcerative; Cytomegalovirus | 2009 |
Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.
Topics: Action Potentials; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Electric Stimulation; Evo | 2011 |
Plasmaexchange in the treatment of myasthenia gravis associated with thymoma.
Topics: Adult; Azathioprine; Cholinesterase Inhibitors; Cyclosporine; Female; Glucocorticoids; Humans; Immun | 2003 |
Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study.
Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Autoantibodies; Azathioprine; Combined Modality Therap | 2003 |
Extrathymic malignancies in patients with myasthenia gravis.
Topics: Adult; Age Factors; Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Disease Progression; Fema | 2005 |
Myasthenia gravis in children: a longitudinal study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Distribution; Age of Onset; Azathioprine; Child; Chi | 2006 |
Hypothermia in VGKC antibody-associated limbic encephalitis.
Topics: Aged; Atrophy; Autoantibodies; Azathioprine; Cyclosporine; Dominance, Cerebral; Epilepsy, Temporal L | 2008 |
[Antibody-controlled cytostatic therapy of malignant thymoma with concomitant myasthenia gravis].
Topics: Acetylcholine; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Cyclophosph | 1984 |
The role of plasma exchange in treatment of myasthenia gravis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Autoantibodies; Azathioprine; Female; Humans; Immunoglobulin G | 1982 |
Plasmapheresis in refractory generalized myasthenia gravis.
Topics: Adult; Aged; Antibodies; Azathioprine; Cholinesterases; Female; Humans; Male; Middle Aged; Myastheni | 1981 |
[Four cases of thymoma associated with pure red cell aplasia].
Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 1997 |
Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients.
Topics: Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Cholinesterase Inhibitors; Cohort Studies; Di | 1997 |
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic | 1998 |
Nonsurgical regression of thymoma following corticosteroid/azathioprine therapy.
Topics: Adrenal Cortex Hormones; Agammaglobulinemia; Azathioprine; Common Variable Immunodeficiency; Humans; | 1999 |
Clinical characteristics and prognosis of myasthenia gravis in older people.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Cholinesterase Inhibitors; Drug The | 2000 |
[Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)].
Topics: Adult; Antibodies, Antinuclear; Azathioprine; Humans; Male; Middle Aged; Myasthenia Gravis; Pyridost | 1977 |
[A case of thymoma with myasthenia gravis and pure red cell aplasia treated with thymectomy and azathioprine (author's transl)].
Topics: Aged; Anemia, Aplastic; Azathioprine; Humans; Male; Myasthenia Gravis; Thymectomy; Thymoma; Thymus N | 1978 |
[Abscess of the thyroid gland caused by Salmonella enteritidis in immunosuppressive treatment of generalized myasthenia gravis with thymoma].
Topics: Abscess; Aged; Azathioprine; Humans; Middle Aged; Myasthenia Gravis; Opportunistic Infections; Risk | 1990 |
[Treatment of invasive thymoma with myasthenia gravis: a case report responsive to azathioprine and methylprednisolone].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Myasthenia Gravis; | 1990 |
Antibody-mediated pure neutrophil aplasia, recurrent myasthenia gravis and previous thymoma: case report and literature review.
Topics: Adult; Agranulocytosis; Antibodies; Azathioprine; Bone Marrow; Female; Humans; Immunosuppression The | 1990 |
The relationship of age to outcome in myasthenia gravis.
Topics: Adrenal Cortex Hormones; Aged; Aging; Antibodies; Autoimmune Diseases; Azathioprine; Combined Modali | 1990 |
Azathioprine as possible explanation of etiology of pure red cell aplasia in myasthenics.
Topics: Adult; Azathioprine; Female; Humans; Myasthenia Gravis; Red-Cell Aplasia, Pure; Thymoma | 1989 |
Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment.
Topics: Antibody Formation; Azathioprine; Bone Marrow Cells; Colony-Forming Units Assay; Erythropoiesis; Fem | 1986 |
Hereditary lymphosarcoma in WH rabbits and hereditary hemolytic anemia associated with thymoma in strain X rabbits.
Topics: Anemia, Hemolytic; Animals; Antigens, Viral; Azathioprine; Complement Fixation Tests; Culture Techni | 1973 |
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis; | 1968 |
[Current results of the treatment of pseudoparalytic myasthenia gravis with immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Antilymphocyte Serum; Azathioprine; Cholinesterase I | 1972 |
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents; | 1973 |
Immunosurveillance and cancer: epidemiological evidence.
Topics: Adolescent; Adult; Age Factors; Aged; Azathioprine; Chediak-Higashi Syndrome; Child; Child, Preschoo | 1970 |
[Anemia caused by erythroblastopenia in adult age].
Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti | 1970 |
Successful immunosuppressive treatment of erythroid aplasia appearing after thymectomy.
Topics: Anemia, Aplastic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Cyclophosphamide; Erythropoies | 1970 |
The development of lymphomas in mice with autoimmune disorders treated with azathioprine.
Topics: Animals; Autoimmune Diseases; Azathioprine; Female; Injections, Intramuscular; Lupus Erythematosus, | 1968 |