azathioprine has been researched along with Cancer of the Thymus in 29 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 7.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| "To evaluate the association between the use of azathioprine and risk of cancer in patients with non-thymoma myasthenia gravis (MG) in a nationwide setting." | 3.79 | Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2013) |
| " Under immunosuppressive treatment with azathioprine and steroids, the patient developed cytomegalovirus (CMV) enteritis which was triggered by therapy-induced leukopenia." | 3.75 | [A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection]. ( Baba, HA; Gerken, G; Kahraman, A; Maldonado-Lopez, E; Miller, M; Treichel, U, 2009) |
| " Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation." | 3.70 | Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998) |
| "6 years after resection and postirradiation of an "asymptomatic" thymoma, myasthenia gravis developed in a 46 year old man which improved within 6 months following initiation of immunosuppressive therapy with azathioprine." | 3.65 | [Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)]. ( Fischer, K; Janzen, RW; Lachenmayer, L, 1977) |
| "Myasthenia gravis is caused by antibodies against acetylcholine receptors and is treated with inhibition or elimination of antibody production." | 2.41 | [A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy]. ( Inoue, Y; Matsuda, O; Takahashi, K; Takemura, T; Yoshimura, A, 2000) |
| "Limbic encephalitis is typically characterised by a sub-acute onset of disorientation, amnesia and seizures, but the clinical spectrum is not yet fully defined and the syndrome could be under-diagnosed." | 1.35 | Hypothermia in VGKC antibody-associated limbic encephalitis. ( Clover, L; Grubneac, A; Irani, SR; Jacob, S; Rajabally, YA; Vincent, A; Walters, RJ; Yazaki, M, 2008) |
| "A group of 16 patients with severe generalized myasthenia gravis (MG) (five with thymoma) that was resistant to anticholinesterases, thymectomy, and corticosteroids were treated by plasmapheresis." | 1.26 | Plasmapheresis in refractory generalized myasthenia gravis. ( Ambinder, EP; Bender, AN; Genkins, G; Goldberg, J; Kornfeld, P; Mittag, T; Papatestas, AE, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (51.72) | 18.7374 |
| 1990's | 7 (24.14) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedersen, EG | 1 |
| Pottegård, A | 1 |
| Hallas, J | 1 |
| Friis, S | 1 |
| Hansen, K | 1 |
| Jensen, PE | 1 |
| Gaist, D | 1 |
| Benjamin, B | 1 |
| Zaltzman, R | 1 |
| Shpitz, B | 1 |
| Gordon, CR | 1 |
| Avital, S | 1 |
| Kahraman, A | 1 |
| Miller, M | 1 |
| Maldonado-Lopez, E | 1 |
| Baba, HA | 1 |
| Treichel, U | 1 |
| Gerken, G | 1 |
| Rigamonti, A | 1 |
| Lauria, G | 1 |
| Piamarta, F | 1 |
| Fiumani, A | 1 |
| Agostoni, E | 1 |
| Romi, F | 1 |
| Gilhus, NE | 1 |
| Varhaug, JE | 1 |
| Myking, A | 1 |
| Aarli, JA | 1 |
| Jacob, S | 1 |
| Irani, SR | 1 |
| Rajabally, YA | 1 |
| Grubneac, A | 1 |
| Walters, RJ | 1 |
| Yazaki, M | 1 |
| Clover, L | 1 |
| Vincent, A | 1 |
| Schumm, F | 1 |
| Brinkmann, A | 1 |
| Fateh-Moghadam, A | 1 |
| Cohen, SM | 1 |
| Erturk, E | 1 |
| Skibba, JL | 1 |
| Bryan, GT | 1 |
| Kornfeld, P | 1 |
| Ambinder, EP | 1 |
| Mittag, T | 1 |
| Bender, AN | 1 |
| Papatestas, AE | 1 |
| Goldberg, J | 1 |
| Genkins, G | 1 |
| Ito, N | 1 |
| Mukaida, T | 1 |
| Aoe, M | 1 |
| Yamashita, M | 1 |
| Date, H | 1 |
| Ando, A | 1 |
| Shimizu, N | 1 |
| Beekman, R | 1 |
| Kuks, JB | 1 |
| Oosterhuis, HJ | 1 |
| Schmidt, S | 1 |
| Padberg, F | 1 |
| Crawford, WW | 1 |
| Yusin, JS | 1 |
| Klaustermeyer, WB | 1 |
| Takahashi, K | 1 |
| Inoue, Y | 1 |
| Matsuda, O | 1 |
| Takemura, T | 1 |
| Yoshimura, A | 1 |
| Janzen, RW | 1 |
| Lachenmayer, L | 1 |
| Fischer, K | 1 |
| Arimori, S | 1 |
| Nakata, Y | 1 |
| Tada, S | 1 |
| Kobashi, H | 1 |
| Koriyama, K | 1 |
| Ichikawa, Y | 1 |
| Mitsuhashi, A | 1 |
| Iwasaki, I | 1 |
| Hiraki, K | 1 |
| Zimmermann, CW | 1 |
| Lingenfelser, T | 1 |
| Melms, A | 1 |
| Jakober, B | 1 |
| Kumagai, M | 1 |
| Kondou, T | 1 |
| Handa, M | 1 |
| Shiraishi, Y | 1 |
| Fujimura, S | 1 |
| Nakata, T | 1 |
| Mathieson, PW | 1 |
| O'Neill, JH | 1 |
| Durrant, ST | 1 |
| Henderson, SJ | 1 |
| Green, PJ | 1 |
| Newsom-Davis, J | 1 |
| Pan, CH | 1 |
| Chiang, CY | 1 |
| Chen, SS | 1 |
| Herrmann, C | 1 |
| Lindstrom, JM | 1 |
| Keesey, JC | 1 |
| Mulder, DG | 1 |
| Krueger, GR | 2 |
| O'Conor, GT | 1 |
| Sussman, E | 1 |
| Tralka, TS | 1 |
| Casey, TP | 1 |
| Ricken, D | 1 |
| Heine, UI | 1 |
| Marmont, A | 1 |
| Gori, E | 1 |
| Krüger, GR | 1 |
| Böttcher, D | 1 |
| Maas, D | 1 |
| Wendt, F | 1 |
| Schubothe, H | 1 |
3 reviews available for azathioprine and Cancer of the Thymus
| Article | Year |
|---|---|
[A case of myasthenia gravis, who developed minimal change nephrotic syndrome during immunosuppressive therapy after thymectomy].
Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Middle Aged; Myasthenia Gravis; Nephrosis, L | 2000 |
Thymolipoma in patients with myasthenia gravis: report of two cases and review.
Topics: Azathioprine; Female; Humans; Lipoma; Middle Aged; Myasthenia Gravis; Prednisolone; Thymus Neoplasms | 1988 |
Myasthenia gravis--current concepts.
Topics: Acetylcholine; Adrenal Cortex Hormones; Adult; Animals; Autoantibodies; Autoimmune Diseases; Azathio | 1985 |
26 other studies available for azathioprine and Cancer of the Thymus
| Article | Year |
|---|---|
Use of azathioprine for non-thymoma myasthenia and risk of cancer: a nationwide case-control study in Denmark.
Topics: Aged; Aged, 80 and over; Azathioprine; Case-Control Studies; Denmark; Female; Humans; Male; Middle A | 2013 |
Presacral Mass Discovered during Pregnancy followed by Myasthenia Gravis.
Topics: Adult; Azathioprine; Castleman Disease; Cholinesterase Inhibitors; Female; Humans; Immunosuppressive | 2015 |
[A 55-year-old woman with thymoma and hypogammaglobulinemia (Good syndrome), ulcerative colitis, and cytomegalovirus infection].
Topics: Agammaglobulinemia; Antiviral Agents; Azathioprine; Cidofovir; Colitis, Ulcerative; Cytomegalovirus | 2009 |
Thymoma-associated myasthenia gravis without acetylcholine receptor antibodies.
Topics: Action Potentials; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Electric Stimulation; Evo | 2011 |
Disease severity and outcome in thymoma myasthenia gravis: a long-term observation study.
Topics: Adrenal Cortex Hormones; Adult; Age of Onset; Autoantibodies; Azathioprine; Combined Modality Therap | 2003 |
Hypothermia in VGKC antibody-associated limbic encephalitis.
Topics: Aged; Atrophy; Autoantibodies; Azathioprine; Cyclosporine; Dominance, Cerebral; Epilepsy, Temporal L | 2008 |
[Antibody-controlled cytostatic therapy of malignant thymoma with concomitant myasthenia gravis].
Topics: Acetylcholine; Antibodies; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Cyclophosph | 1984 |
Azathioprine induction of lymphomas and squamous cell carcinomas in rats.
Topics: Animals; Azathioprine; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Lymphoma; Rats; Rats, Inbred | 1983 |
Plasmapheresis in refractory generalized myasthenia gravis.
Topics: Adult; Aged; Antibodies; Azathioprine; Cholinesterases; Female; Humans; Male; Middle Aged; Myastheni | 1981 |
[Treatment of myasthenia gravis--pathophysiological evaluation of various forms of treatment and practical aspects of therapy (author's transl)].
Topics: Azathioprine; Cholinesterase Inhibitors; Evaluation Studies as Topic; Humans; Myasthenia Gravis; Pla | 1980 |
[Four cases of thymoma associated with pure red cell aplasia].
Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 1997 |
Myasthenia gravis: diagnosis and follow-up of 100 consecutive patients.
Topics: Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Cholinesterase Inhibitors; Cohort Studies; Di | 1997 |
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic | 1998 |
Nonsurgical regression of thymoma following corticosteroid/azathioprine therapy.
Topics: Adrenal Cortex Hormones; Agammaglobulinemia; Azathioprine; Common Variable Immunodeficiency; Humans; | 1999 |
[Problems of postthymectomy-syndromes, e.g. myasthenia gravis (author's transl)].
Topics: Adult; Antibodies, Antinuclear; Azathioprine; Humans; Male; Middle Aged; Myasthenia Gravis; Pyridost | 1977 |
[A case of thymoma with myasthenia gravis and pure red cell aplasia treated with thymectomy and azathioprine (author's transl)].
Topics: Aged; Anemia, Aplastic; Azathioprine; Humans; Male; Myasthenia Gravis; Thymectomy; Thymoma; Thymus N | 1978 |
[Abscess of the thyroid gland caused by Salmonella enteritidis in immunosuppressive treatment of generalized myasthenia gravis with thymoma].
Topics: Abscess; Aged; Azathioprine; Humans; Middle Aged; Myasthenia Gravis; Opportunistic Infections; Risk | 1990 |
[Treatment of invasive thymoma with myasthenia gravis: a case report responsive to azathioprine and methylprednisolone].
Topics: Adult; Azathioprine; Drug Therapy, Combination; Humans; Male; Methylprednisolone; Myasthenia Gravis; | 1990 |
Antibody-mediated pure neutrophil aplasia, recurrent myasthenia gravis and previous thymoma: case report and literature review.
Topics: Adult; Agranulocytosis; Antibodies; Azathioprine; Bone Marrow; Female; Humans; Immunosuppression The | 1990 |
Ultrastructural and tissue culture studies of a thymic lymphoma induced by persistent antigenic stimulation and immunosuppression.
Topics: Animals; Antigens, Neoplasm; Azathioprine; Cells, Cultured; Cross Reactions; Immunosuppression Thera | 1973 |
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis; | 1968 |
[Current results of the treatment of pseudoparalytic myasthenia gravis with immunosuppressive agents].
Topics: Adrenocorticotropic Hormone; Adult; Antibodies; Antilymphocyte Serum; Azathioprine; Cholinesterase I | 1972 |
Morphogenesis of two immunologically induced mouse lymphomas.
Topics: Animals; Azathioprine; Cells, Cultured; Female; Hodgkin Disease; Liver; Lung; Lymph Nodes; Mice; Mic | 1972 |
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents; | 1973 |
Host response during the latent period and the growth of an immunologically induced mouse lymphoma.
Topics: Animals; Antibody Formation; Antigens, Neoplasm; Azathioprine; Cross Reactions; Female; Freund's Adj | 1972 |
[Anemia caused by erythroblastopenia in adult age].
Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti | 1970 |