azathioprine has been researched along with Cancer of Spleen in 16 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "We report the first 2 cases of hepatosplenic T-cell lymphoma in adolescents diagnosed with autoimmune hepatitis under long-term treatment with azathioprine." | 3.83 | Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis. ( Arrenberg, P; Brinkert, F; Grabhorn, E; Krech, T; Lohse, A; Schramm, C, 2016) |
| "All azathioprine treated mice showed signs of drug-associated toxicity such as weight loss and development of splenic T-cell lymphomas." | 3.80 | Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis. ( D'Haens, GR; Heijmans, J; Jansen, M; Levin, AD; Muncan, V; Rosekrans, SL; Schukking, M; van den Brink, GR; van Lidth de Jeude, JF; Wielenga, MC, 2014) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "A further case of subsepsis allergica Wissler in a 35-year-old woman is reported." | 1.25 | [A further case of Wissler's allergic subsepticemia in an adult]. ( Finke, EJ; Kraatz, G; Ratzmann, KP; Schlenzka, K; Zimmermann, E, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mavilia, M | 1 |
| McAuliffe, A | 1 |
| Hafeez, S | 1 |
| Vaziri, H | 1 |
| Wielenga, MC | 1 |
| van Lidth de Jeude, JF | 1 |
| Rosekrans, SL | 1 |
| Levin, AD | 1 |
| Schukking, M | 1 |
| D'Haens, GR | 1 |
| Heijmans, J | 1 |
| Jansen, M | 1 |
| Muncan, V | 1 |
| van den Brink, GR | 1 |
| Brinkert, F | 1 |
| Arrenberg, P | 1 |
| Krech, T | 1 |
| Grabhorn, E | 1 |
| Lohse, A | 1 |
| Schramm, C | 1 |
| van de Meeberg, MM | 1 |
| Derikx, LA | 1 |
| Sinnige, HA | 1 |
| Nooijen, P | 1 |
| Schipper, DL | 1 |
| Nissen, LH | 1 |
| Moran, G | 1 |
| Dillon, J | 1 |
| Green, J | 1 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Ochenrider, MG | 1 |
| Patterson, DJ | 1 |
| Aboulafia, DM | 1 |
| Thai, A | 1 |
| Prindiville, T | 1 |
| Cappello, M | 1 |
| Bravatà, I | 1 |
| Cocorullo, G | 1 |
| Cacciatore, M | 1 |
| Florena, AM | 1 |
| Rashidi, A | 1 |
| Lee, ME | 1 |
| Fisher, SI | 1 |
| Bašić Kinda, S | 1 |
| Duraković, N | 1 |
| Dotlić, S | 1 |
| Serventi Seiwerth, R | 1 |
| Davidović Mrsić, S | 1 |
| Dubravčić, K | 1 |
| Aurer, I | 1 |
| Navarro, JT | 1 |
| Ribera, JM | 1 |
| Mate, JL | 1 |
| Granada, I | 1 |
| Juncà, J | 1 |
| Batlle, M | 1 |
| Millá, F | 1 |
| Feliu, E | 1 |
| Berliner, S | 1 |
| Shoenfeld, Y | 1 |
| Sidi, Y | 1 |
| Santo, M | 1 |
| Weinberger, A | 1 |
| Luria, D | 1 |
| Hazaz, B | 1 |
| Pecht, M | 1 |
| Zaizov, R | 1 |
| Pinkhas, J | 1 |
| Ratzmann, KP | 1 |
| Finke, EJ | 1 |
| Kraatz, G | 1 |
| Schlenzka, K | 1 |
| Zimmermann, E | 1 |
| Casey, TP | 1 |
| Kotlyar, DS | 1 |
| Blonski, W | 1 |
| Diamond, RH | 1 |
| Wasik, M | 1 |
| Lichtenstein, GR | 1 |
3 reviews available for azathioprine and Cancer of Spleen
| Article | Year |
|---|---|
Hepatosplenic T-cell lymphoma in a young man with Crohn's disease: case report and literature review.
Topics: Adalimumab; Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Ag | 2010 |
Hepatosplenic T-cell lymphoma and inflammatory bowel disease.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Humans; Immunophenotyping; Immunosup | 2010 |
Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality.
Topics: Chromosome Disorders; Humans; Inflammatory Bowel Diseases; Lymphoma, T-Cell; Mercaptopurine; Splenic | 2010 |
13 other studies available for azathioprine and Cancer of Spleen
| Article | Year |
|---|---|
Hepatosplenic T cell lymphoma: a unifying entity in a patient with hemolytic anemia, massive splenomegaly, and liver dysfunction.
Topics: Adult; Anemia, Hemolytic; Azathioprine; Biopsy; Chronic Disease; Colitis, Ulcerative; Fatal Outcome; | 2018 |
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Azathioprine; Female; Genes, APC; Lymp | 2014 |
Two Cases of Hepatosplenic T-Cell Lymphoma in Adolescents Treated for Autoimmune Hepatitis.
Topics: Adolescent; Azathioprine; Female; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Neo | 2016 |
Hepatosplenic T-cell lymphoma in a 47-year-old Crohn's disease patient on thiopurine monotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biopsy; Crohn Disease; Drug Administra | 2016 |
Crohn's disease, hepatosplenic T-cell lymphoma and no biological therapy: are we barking up the wrong tree?
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Therapy, Combination; Glucocorticoids; Humans | 2009 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Splenic littoral cell hemangioendothelioma in a patient with Crohn's disease previously treated with immunomodulators and anti-TNF agents: a rare tumor linked to deep immunosuppression.
Topics: Azathioprine; Colonic Diseases; Crohn Disease; Gastrointestinal Agents; Hemangioendothelioma; Hemang | 2011 |
Hepatosplenic αβ T-cell lymphoma associated with azathioprine therapy.
Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Liver Neoplasms; Lupus Erythematosus, System | 2012 |
Hepatosplenic αβ T-cell lymphoma arising after long-term azathioprine therapy successfully treated with allogeneic bone marrow transplant.
Topics: Azathioprine; Bone Marrow Transplantation; Crohn Disease; Humans; Immunosuppressive Agents; Liver Ne | 2013 |
Hepatosplenic T-gammadelta lymphoma in a patient with Crohn's disease treated with azathioprine.
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; | 2003 |
Systemic lupus erythematosus and lymphoma. A family study.
Topics: Adult; Autoimmune Diseases; Azathioprine; Child; Drug Therapy, Combination; Female; Humans; Killer C | 1983 |
[A further case of Wissler's allergic subsepticemia in an adult].
Topics: Adult; Azathioprine; Diagnosis, Differential; Female; Humans; Prednisolone; Splenic Neoplasms; Wissl | 1975 |
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis; | 1968 |