azathioprine has been researched along with Cancer of Skin in 165 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent studies have reported a significant increase of proteinuria in kidney transplant recipients who were switched from a calcineurin inhibitor (CI) to sirolimus." | 9.12 | Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients. ( Hoitsma, AJ; van den Akker, JM; Wetzels, JF, 2006) |
| "Increased rates of NMSC (nonmelanoma skin cancer) have recently been reported in people with MG (myasthenia gravis) receiving azathioprine treatment." | 7.81 | Nonmelanoma skin cancer risk awareness in azathioprine-treated myasthenia gravis patients. ( McGuigan, C; McGurgan, IJ, 2015) |
| "While being treated with azathioprine and dexamethasone, a 21-year old man with myasthenia gravis suddenly developed rapidly progressing brown macules, predominantly on the trunk, palms and soles." | 7.78 | [Eruptive melanocytic nevi during azathioprine therapy in myasthenia gravis]. ( Braun, SA; Frank, J; Hanneken, S; Helbig, D, 2012) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "Recent studies have reported a significant increase of proteinuria in kidney transplant recipients who were switched from a calcineurin inhibitor (CI) to sirolimus." | 5.12 | Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients. ( Hoitsma, AJ; van den Akker, JM; Wetzels, JF, 2006) |
| "We have investigated some possible risk factors for cutaneous warts in a consecutive group of renal transplant recipients treated with three different immunosuppressive regimens: prednisolone + azathioprine (PA), prednisolone + azathioprine + cyclosporin (PAC), prednisolone + cyclosporin (PC)." | 5.08 | Analysis of risk factors for cutaneous warts in renal transplant recipients. ( Barba, A; Chieregato, GC; Talamini, G; Tessari, G, 1997) |
| " Warts (30%) had the larger incidence and were associated with azathioprine (P = 0." | 3.91 | Skin lesions in organ transplant recipients: a study of 177 consecutive Brazilian patients. ( Codarin, FR; Festa Neto, C; Oliveira, WRP; Silva, LLC; Souza, AAV; Tirico, MCCP, 2019) |
| "We assessed two patients with multiple sclerosis who were on treatment with dimethylfumarate (DMF) preceded by long-term azathioprine therapy." | 3.88 | Altered epigenetic pathways and cell cycle dysregulation in healthy appearing skin of patients with koebnerized squamous cell carcinomas following skin surgery. ( Bechara, FG; Gambichler, T; Hessam, S; Rüddel, I; Schmitz, L; Stockfleth, E, 2018) |
| "Increased rates of NMSC (nonmelanoma skin cancer) have recently been reported in people with MG (myasthenia gravis) receiving azathioprine treatment." | 3.81 | Nonmelanoma skin cancer risk awareness in azathioprine-treated myasthenia gravis patients. ( McGuigan, C; McGurgan, IJ, 2015) |
| "While being treated with azathioprine and dexamethasone, a 21-year old man with myasthenia gravis suddenly developed rapidly progressing brown macules, predominantly on the trunk, palms and soles." | 3.78 | [Eruptive melanocytic nevi during azathioprine therapy in myasthenia gravis]. ( Braun, SA; Frank, J; Hanneken, S; Helbig, D, 2012) |
| "Immunodeficiency-related lymphoproliferative disorders (IR-LPD) may occur in the setting of immunosuppressive therapy with methotrexate and TNF-α antagonists." | 3.77 | Transient iatrogenic immunodeficiency-related B-cell lymphoproliferative disorder of the skin in a patient with mycosis fungoides/Sézary syndrome. ( Curry, JL; Diwan, AH; Duvic, M; Jones, DM; Prieto, VG; Vega, F, 2011) |
| "To investigate (i) whether loss of MMR protein expression and microsatellite instability are over-represented in squamous cell carcinomas (SCCs) from OTRs on azathioprine compared with SCCs from immunocompetent patients, and (ii) whether the MSH2 -6 exon 13 polymorphism is over-represented in OTRs with skin cancer on azathioprine." | 3.76 | Expression of DNA mismatch repair proteins and MSH2 polymorphisms in nonmelanoma skin cancers of organ transplant recipients. ( Cerio, R; Harwood, CA; Karran, P; McGregor, JM; Perrett, CM; Warwick, J, 2010) |
| "We report two cases of stage IV malignant melanoma arising in patients treated with azathioprine for myasthenia gravis." | 3.76 | Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review. ( Collichio, F; Dillon, P; Sharpless, N; Thomas, N, 2010) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " We report two cases where multifocal Kaposi's sarcoma developed following iatrogenic immunosuppression with prednisolone and azathioprine for bullous pemphigoid." | 3.69 | Kaposi's sarcoma associated with immunosuppression for bullous pemphigoid. ( Cerio, R; Halpern, SM; Kirby, JT; Parslew, R; Sharpe, GR, 1997) |
| " He had CD4 lymphocytopenia during azathioprine and topical corticosteroid therapy for atopic dermatitits (AD)." | 3.69 | Kaposi's sarcoma during immunosuppressive therapy for atopic dermatitis. ( Janssens, P; Lachapelle, JM; Lambert, M; Tennstedt, D; Vandercam, B, 1997) |
| "A prospective study in the United Kingdom of 1,634 patients without transplants treated with immunosuppressive drugs (68 percent with azathioprine, 28 percent with cyclophosphamide) found an excess of non-Hodgkin's lymphoma and squamous cell skin cancer, suggesting that the excesses (although larger) of the same malignancies found among transplant recipients are not due solely to the foreign antigens of the graft." | 3.67 | Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. ( Kinlen, LJ, 1985) |
| "Heart transplant recipients experience high rates of skin cancer, likely due to greater length or dosage of immunosuppression." | 3.01 | A review of heart transplant immunosuppressants and nonmelanoma skin cancer. ( Camacho, I; Dave, Y; Eckembrecher, DG; Eckembrecher, FJ; Nouri, K; Patel, S; Shah, H, 2023) |
| "However, the risk of acquiring skin cancer increases with the length of immunosuppressive therapy." | 2.67 | No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective. ( Blohmé, I; Larkö, O, 1992) |
| "The overall malignancy risk in patients with AAV has decreased, most likely as a result of recent changes in therapeutic regimen, that is, a decrease in the exposure to cyclophosphamide." | 2.58 | Antineutrophil cytoplasmic antibody-associated vasculitis and malignancy. ( Bajema, IM; van Daalen, EE; Wester Trejo, MAC, 2018) |
| "Three cases of basal cell carcinoma in Crohn's disease patients treated with azathioprine are described." | 2.52 | Crohn's Disease treated with azathioprine and basal cell carcinoma : three cases and literature review. ( Borgies, P; Dubois, A; El Nawar, A; Gallez, JF; Moreels, T; Nakad, A; Patris, A; Rahier, JF; Tennstedt, D; Vandenbulcke, H, 2015) |
| "This cancer excess was largely driven by an increased incidence of NMSC." | 2.47 | Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from European Vasculitis Study Group clinical trials. ( Flossmann, O; Harper, L; Heijl, C; Höglund, P; Mahr, A; Scott, DG; Stücker, I; Watts, RA; Westman, K, 2011) |
| "Skin cancer is the most common form of cancer in the United States; the nonmelanoma skin cancers have an annual incidence of greater than 1,000,000 people in the US." | 2.44 | Risk of nonmelanoma skin cancer with azathioprine use. ( Maddox, JS; Soltani, K, 2008) |
| "The frequency of posttransplantation tumors is 2 to 4-fold compared to the non-transplanted population, and the distribution of tumor types is also different." | 2.44 | [Malignant tumors following renal transplantation]. ( Járay, J; Végso, G, 2007) |
| "In fact, it is expected that cancer will surpass cardiovascular complications as the leading cause of death in transplant patients within the next 2 decades." | 2.43 | Malignancy after transplantation. ( Buell, JF; Gross, TG; Woodle, ES, 2005) |
| "The use of MMF is associated with slight increases in gastrointestinal adverse effects, some hematologic adverse events, and CMV infections compared with Aza." | 2.42 | Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review. ( Li, H; Li, Y; Lu, Y; Wang, K; Wei, Q; Yang, Y; Zhang, H, 2004) |
| "Incident cases of non-melanoma skin cancers and non-Hodgkin lymphoma diagnosed after prescription of thiopurine and/or anti-tumor necrosis factor-α were identified between April 2008 and January 2018." | 1.56 | Lack of Increased Risk of Lymphoma by Thiopurines or Biologics in Japanese Patients with Inflammatory Bowel Disease: A Large-Scale Administrative Database Analysis. ( Hibi, T; Kobayashi, T; Uda, A; Udagawa, E, 2020) |
| "Cases of Merkel cell carcinoma have become increasingly more common in the last two decades, and its incidence has been predicted to climb further." | 1.51 | Inferior outcomes in immunocompromised Merkel cell carcinoma patients: Can they be overcome by the use of PD1/PDL1 inhibitors? ( Codreanu, I; Dasanu, CA; Del Rosario, M; Hyams, DM; Plaxe, SC, 2019) |
| "Lymphomatoid granulomatosis is a rare lymphoproliferative disorder associated with immunosuppressive therapy in inflammatory bowel disease." | 1.51 | A rare lymphoproliferative disorder associated with immunomodulating therapy in Crohn's disease. ( Curieses Luengo, M; López Fernández, E; Varela Trastoy, P, 2019) |
| "Cutaneous squamous cell carcinoma (cSCC) has a high tumour mutational burden (50 mutations per megabase DNA pair)." | 1.48 | The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature. ( Alexandrov, LB; Chelala, C; Harwood, CA; Hogan, S; Inman, GJ; Leigh, IM; Nagano, A; Proby, CM; Purdie, KJ; Sherwood, V; South, AP; Spender, LC; Stratton, M; Taylor, RG; Thomson, J; Wang, J, 2018) |
| "Anorectal malignant melanoma is often misdiagnosed as either hemorrhoids or benign anorectal conditions in inflammatory bowel disease." | 1.46 | Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis. ( Kim, SE; Moon, W; Park, MI; Park, SJ; Seo, KI, 2017) |
| "Eruptive melanocytic nevi (EMN) are rare multiple benign melanocytic nevi that develop within a few months." | 1.46 | Eruptive melanocytic nevi during azathioprine therapy for antisynthetase syndrome. ( Dronavalli, S; Halvorson, CR; Kao, GF; Steinweg, SA, 2017) |
| "Treatment with azathioprine has been proven to increase the risk of non-melanoma skin cancer (NMSC) in transplant patients and possibly in patients with inflammatory bowel disease as well." | 1.40 | Increased incidence of squamous cell carcinoma of the skin after long-term treatment with azathioprine in patients with auto-immune inflammatory rheumatic diseases. ( de Jong, EM; Hendriks, JC; Janssen, M; Schers, HJ; Seyger, MM; van de Kerkhof, PC; van den Reek, JM; van Lümig, PP, 2014) |
| " Conditional logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (CI) for skin cancer associated with a high cumulative dose (≥150 g) or long-term use (≥5 years) of azathioprine, adjusted for confounders." | 1.40 | Risk of non-melanoma skin cancer in myasthenia patients treated with azathioprine. ( Friis, S; Gaist, D; Hallas, J; Hansen, K; Jensen, PE; Pedersen, EG; Pottegård, A, 2014) |
| "The most common skin cancer in the population was squamous cell carcinoma." | 1.39 | Gene expression profiling for cardiac rejection surveillance is not predictive of post-transplantation skin cancer. ( Chen, H; Fang, F; Hanlon, A; Lott, J; O'Neill, M; Stasko, T; Wigger, M, 2013) |
| "A diagnosis of non-melanoma skin cancer was significantly associated with thiopurine exposure (odds ratio 5." | 1.38 | Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study. ( Epstein, D; Hift, R; Myer, L; Setshedi, M; Watermeyer, G; Winter, TA, 2012) |
| "Pathology revealed T1aNxM0 pleomorphic malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma." | 1.38 | Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis. ( Daw, HA; Sood, R, 2012) |
| "This report presents a patient with ulcerative colitis who developed Kaposi's sarcoma following treatment with long-term medium-dose azathioprine and additional corticosteroids." | 1.37 | Kaposi's sarcoma in patients with ulcerative colitis receiving immunosuppressive drugs: report of a case. ( Beneklı, M; Büyükberber, S; Cetın, B; Coşkun, U; Yildiz, R; Yilmaz, IB, 2011) |
| "Overall incidence of neoplasias was 30." | 1.36 | Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal. ( Celik, S; Dengler, TJ; Doesch, AO; Ehlermann, P; Frankenstein, L; Katus, HA; Konstandin, M; Kristen, A; Müller, S; Sack, FU, 2010) |
| "The risk of skin cancer is highly increased in kidney-transplant recipients (KTR), but the risk of subsequent skin cancers is less well studied." | 1.36 | Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors. ( Bavinck, JN; Claas, FH; de Fijter, JW; Edelbroek, JR; Haasnoot, GW; Willemze, R; Wisgerhof, HC, 2010) |
| "The risk of cutaneous squamous cell carcinoma (CSCC) is found to be substantially increased after organ transplantation." | 1.36 | Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma. ( Adami, J; Bellocco, R; Fernberg, P; Höglund, P; Ingvar, A; Lindelöf, B; Smedby, KE; Tufveson, G, 2010) |
| "We evaluated the incidence of cancer in a Cancer Risk In MS Cohort." | 1.35 | Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis. ( Berthier, F; Clavelou, P; Danzon, A; de Seze, J; Debouverie, M; Defer, G; Gout, O; Lebrun, C; Rumbach, L; Vermersch, P; Wiertlevski, S, 2008) |
| "Squamous cell carcinoma was the most common malignant skin lesion and 84% of all lesions occurred in sun-exposed areas." | 1.33 | Skin cancer in renal allograft recipients--experience in different ethnic groups residing in the same geographical region. ( Gralla, J; Moosa, MR, 2005) |
| "Non-melanoma skin cancer is frequent in organ transplant recipients." | 1.31 | Are heart transplant recipients more likely to develop skin cancer than kidney transplant recipients? ( Fauchald, P; Geiran, O; Gjersvik, P; Hansen, S; Leivestad, T; Møller, B; Pfeffer, P; Simonsen, S, 2000) |
| "Azathioprine and cyclosporin have been used as immunosuppressants for many years, but long-term use has also been associated with neoplasia." | 1.30 | Merkel cell carcinoma arising after therapeutic immunosuppression. ( Bunker, CB; Gooptu, C; Morris, PJ; Price, M; Ross, J; Wall, S; Wojnarowska, F; Woollons, A, 1997) |
| "Four epidemiologic types of Kaposi sarcoma (KS) are known: classic KS, endemic African KS, epidemic or acquired immunodeficiency syndrome-related KS, and KS associated with immunosuppressive therapy." | 1.29 | The appearance of Kaposi sarcoma during corticosteroid therapy. ( David, M; Hodak, E; Sandbank, M; Trattner, A, 1993) |
| "In 7 transplant recipients with skin cancer, the mean SCE frequency was 14." | 1.27 | Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer. ( Kelly, GE; Sheil, AG, 1983) |
| "Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc." | 1.25 | [Side effects in immunosuppressive therapy]. ( Thumb, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (30.30) | 18.7374 |
| 1990's | 34 (20.61) | 18.2507 |
| 2000's | 27 (16.36) | 29.6817 |
| 2010's | 49 (29.70) | 24.3611 |
| 2020's | 5 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Ranjan, MK | 1 |
| Kante, B | 1 |
| Vuyyuru, SK | 1 |
| Kumar, P | 1 |
| Mundhra, SK | 1 |
| Golla, R | 1 |
| Sharma, R | 1 |
| Sahni, P | 1 |
| Das, P | 1 |
| Makharia, G | 1 |
| Kedia, S | 1 |
| Ahuja, V | 1 |
| Eckembrecher, DG | 1 |
| Eckembrecher, FJ | 1 |
| Camacho, I | 1 |
| Shah, H | 1 |
| Dave, Y | 1 |
| Patel, S | 1 |
| Nouri, K | 1 |
| Jansen, FM | 1 |
| den Broeder, N | 1 |
| Lubeek, SFK | 1 |
| Savelkoul, EHJ | 1 |
| Marcus, CM | 1 |
| Hoentjen, F | 1 |
| van Dop, WA | 1 |
| Wu, Y | 1 |
| Ghaly, S | 1 |
| Kerr, S | 1 |
| Jackson, B | 1 |
| Hanigan, K | 1 |
| Martins, D | 1 |
| Krishnaprasad, K | 1 |
| Mountifield, RE | 1 |
| Whiteman, DC | 1 |
| Bampton, PA | 1 |
| Gearry, RB | 1 |
| Radford-Smith, GL | 1 |
| Lawrance, IC | 1 |
| Steinweg, SA | 1 |
| Halvorson, CR | 1 |
| Kao, GF | 1 |
| Dronavalli, S | 1 |
| Seo, KI | 1 |
| Moon, W | 1 |
| Kim, SE | 1 |
| Park, MI | 1 |
| Park, SJ | 1 |
| Nishizawa, A | 1 |
| Ishikawa, T | 1 |
| Hirose, M | 1 |
| Satoh, H | 1 |
| Nishii, S | 1 |
| Tomita, K | 1 |
| Hokari, R | 1 |
| Satoh, T | 1 |
| Wester Trejo, MAC | 1 |
| Bajema, IM | 1 |
| van Daalen, EE | 1 |
| Cho, HG | 1 |
| Kuo, KY | 1 |
| Xiao, K | 1 |
| Batra, P | 1 |
| Li, S | 1 |
| Tang, JY | 1 |
| Sarin, KY | 1 |
| Kim, JH | 1 |
| Kim, JW | 1 |
| Gambichler, T | 1 |
| Rüddel, I | 1 |
| Hessam, S | 1 |
| Bechara, FG | 1 |
| Stockfleth, E | 2 |
| Schmitz, L | 1 |
| Vos, M | 1 |
| Plasmeijer, EI | 1 |
| van Bemmel, BC | 1 |
| van der Bij, W | 1 |
| Klaver, NS | 1 |
| Erasmus, ME | 1 |
| de Bock, GH | 1 |
| Verschuuren, EAM | 1 |
| Rácz, E | 1 |
| Dasanu, CA | 1 |
| Del Rosario, M | 1 |
| Codreanu, I | 1 |
| Hyams, DM | 1 |
| Plaxe, SC | 1 |
| Inman, GJ | 2 |
| Wang, J | 1 |
| Nagano, A | 1 |
| Alexandrov, LB | 1 |
| Purdie, KJ | 1 |
| Taylor, RG | 1 |
| Sherwood, V | 1 |
| Thomson, J | 1 |
| Hogan, S | 1 |
| Spender, LC | 1 |
| South, AP | 1 |
| Stratton, M | 1 |
| Chelala, C | 1 |
| Harwood, CA | 6 |
| Proby, CM | 3 |
| Leigh, IM | 3 |
| Huang, SZ | 1 |
| Liu, ZC | 1 |
| Liao, WX | 1 |
| Wei, JX | 1 |
| Huang, XW | 1 |
| Yang, C | 1 |
| Xia, YH | 1 |
| Li, L | 1 |
| Ye, C | 1 |
| Dai, SX | 1 |
| Oliveira, WRP | 1 |
| Tirico, MCCP | 1 |
| Souza, AAV | 1 |
| Codarin, FR | 1 |
| Silva, LLC | 1 |
| Festa Neto, C | 1 |
| Khan, N | 1 |
| Lee, H | 1 |
| Trivedi, C | 1 |
| Kavani, H | 1 |
| Medvedeva, E | 1 |
| Xie, D | 1 |
| Lewis, JD | 1 |
| Yang, YX | 1 |
| López Fernández, E | 1 |
| Curieses Luengo, M | 1 |
| Varela Trastoy, P | 1 |
| Comfere, NI | 1 |
| Ikediobi, ON | 1 |
| Peters, MS | 1 |
| el-Azhary, RA | 1 |
| Gibson, LE | 1 |
| Hanlon, A | 1 |
| O'Neill, M | 1 |
| Fang, F | 1 |
| Chen, H | 1 |
| Lott, J | 1 |
| Wigger, M | 1 |
| Stasko, T | 1 |
| Pedersen, EG | 1 |
| Pottegård, A | 1 |
| Hallas, J | 1 |
| Friis, S | 1 |
| Hansen, K | 1 |
| Jensen, PE | 1 |
| Gaist, D | 1 |
| Imko-Walczuk, B | 2 |
| Kryś, A | 1 |
| Lizakowski, S | 1 |
| Dębska-Ślizień, A | 2 |
| Rutkowski, B | 2 |
| Biernat, W | 1 |
| Wojnarowska, F | 2 |
| Rivinius, R | 1 |
| Helmschrott, M | 1 |
| Ruhparwar, A | 1 |
| Schmack, B | 1 |
| Klein, B | 1 |
| Erbel, C | 1 |
| Gleissner, CA | 1 |
| Akhavanpoor, M | 1 |
| Frankenstein, L | 2 |
| Darche, FF | 1 |
| Thomas, D | 1 |
| Ehlermann, P | 2 |
| Bruckner, T | 1 |
| Katus, HA | 2 |
| Doesch, AO | 2 |
| Clarke, CA | 1 |
| Robbins, HA | 1 |
| Tatalovich, Z | 1 |
| Lynch, CF | 1 |
| Pawlish, KS | 1 |
| Finch, JL | 1 |
| Hernandez, BY | 1 |
| Fraumeni, JF | 1 |
| Madeleine, MM | 1 |
| Engels, EA | 1 |
| Burke, MT | 2 |
| Isbel, N | 1 |
| Barraclough, KA | 1 |
| Jung, JW | 1 |
| Wells, JW | 1 |
| Staatz, CE | 1 |
| Canha, C | 1 |
| Ferreira, R | 1 |
| Rovira, J | 1 |
| Moya-Rull, D | 1 |
| Castells, A | 1 |
| Diekmann, F | 1 |
| Oppenheimer, F | 2 |
| Campistol, JM | 1 |
| Revuelta, I | 1 |
| McGurgan, IJ | 1 |
| McGuigan, C | 1 |
| Vandenbulcke, H | 1 |
| Borgies, P | 1 |
| Dubois, A | 1 |
| Patris, A | 1 |
| Gallez, JF | 1 |
| El Nawar, A | 1 |
| Rahier, JF | 1 |
| Moreels, T | 1 |
| Tennstedt, D | 2 |
| Nakad, A | 1 |
| Jiyad, Z | 1 |
| Olsen, CM | 1 |
| Isbel, NM | 1 |
| Green, AC | 1 |
| Piesiaków, ML | 1 |
| Trzonkowski, P | 1 |
| Pikuła, M | 1 |
| Narula, N | 1 |
| Steinhart, AH | 1 |
| Attard, NR | 2 |
| O'Donovan, P | 2 |
| Chambers, P | 1 |
| Perrett, CM | 4 |
| McGregor, JM | 4 |
| Karran, P | 5 |
| Wisgerhof, HC | 2 |
| Hameetman, L | 1 |
| Tensen, CP | 1 |
| Morreau, H | 1 |
| de Fijter, JW | 2 |
| Bouwes Bavinck, JN | 2 |
| Willemze, R | 3 |
| de Gruijl, FR | 2 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Ingvar, A | 1 |
| Smedby, KE | 1 |
| Lindelöf, B | 1 |
| Fernberg, P | 1 |
| Bellocco, R | 1 |
| Tufveson, G | 1 |
| Höglund, P | 2 |
| Adami, J | 1 |
| Warwick, J | 2 |
| Cerio, R | 2 |
| Curry, JL | 1 |
| Prieto, VG | 1 |
| Jones, DM | 1 |
| Vega, F | 1 |
| Duvic, M | 2 |
| Diwan, AH | 1 |
| Dillon, P | 1 |
| Thomas, N | 1 |
| Sharpless, N | 1 |
| Collichio, F | 1 |
| Fogo, AJ | 1 |
| Hunt, JB | 1 |
| Clement, M | 1 |
| McAleer, MA | 1 |
| D'Arcy, CA | 1 |
| Mulligan, NJ | 1 |
| Sheahan, K | 1 |
| Collins, P | 1 |
| Edelbroek, JR | 1 |
| Haasnoot, GW | 1 |
| Claas, FH | 1 |
| Bavinck, JN | 1 |
| Müller, S | 1 |
| Konstandin, M | 1 |
| Celik, S | 1 |
| Kristen, A | 1 |
| Sack, FU | 1 |
| Dengler, TJ | 1 |
| Heijl, C | 1 |
| Harper, L | 1 |
| Flossmann, O | 1 |
| Stücker, I | 1 |
| Scott, DG | 1 |
| Watts, RA | 1 |
| Westman, K | 1 |
| Mahr, A | 1 |
| Setshedi, M | 1 |
| Epstein, D | 1 |
| Winter, TA | 1 |
| Myer, L | 1 |
| Watermeyer, G | 1 |
| Hift, R | 1 |
| Lamchahab, FE | 1 |
| Tadlaoui, I | 1 |
| Beqqal, K | 1 |
| Bouattar, T | 1 |
| Ouzeddoun, N | 1 |
| Bayahia, R | 1 |
| Ait Ourhroui, M | 1 |
| Senouci, K | 1 |
| Hassam, B | 1 |
| Ismaili, N | 1 |
| Rojas-Feria, M | 1 |
| Eslam, M | 1 |
| Castro-Fernández, M | 1 |
| Guerrero, P | 1 |
| Larraona-Moreno, JL | 1 |
| Romero-Gómez, M | 1 |
| Subramaniam, K | 1 |
| Pavli, P | 1 |
| Cetın, B | 1 |
| Büyükberber, S | 1 |
| Yilmaz, IB | 1 |
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26 reviews available for azathioprine and Cancer of Skin
| Article | Year |
|---|---|
A review of heart transplant immunosuppressants and nonmelanoma skin cancer.
Topics: Azathioprine; Everolimus; Heart Transplantation; Humans; Immunosuppressive Agents; Mycophenolic Acid | 2023 |
Antineutrophil cytoplasmic antibody-associated vasculitis and malignancy.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antirheumatic Agents; Azathioprine; Cycl | 2018 |
[Effect of Immunomodulators and Biologic Agents on Malignancy in Patients with Inflammatory Bowel Disease].
Topics: Adalimumab; Azathioprine; Biological Factors; Female; Humans; Immunosuppressive Agents; Inflammatory | 2017 |
Risk of skin cancers in thiopurines-treated and thiopurines-untreated patients with inflammatory bowel disease: A systematic review and meta-analysis.
Topics: Azathioprine; Databases, Bibliographic; Humans; Inflammatory Bowel Diseases; Melanoma; Mercaptopurin | 2019 |
Pharmacogenetics in dermatology: a patient-centered update.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineo | 2013 |
Genetics and nonmelanoma skin cancer in kidney transplant recipients.
Topics: Azathioprine; Calcineurin Inhibitors; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transpl | 2015 |
Crohn's Disease treated with azathioprine and basal cell carcinoma : three cases and literature review.
Topics: Adult; Azathioprine; Carcinoma, Basal Cell; Crohn Disease; Female; Humans; Immunosuppressive Agents; | 2015 |
Azathioprine and Risk of Skin Cancer in Organ Transplant Recipients: Systematic Review and Meta-Analysis.
Topics: Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Graft Rejection; Humans; Immunosuppre | 2016 |
Carcinogenic mechanisms related to immunosuppressive therapy.
Topics: Azathioprine; Carcinogens; Cyclosporine; Glucocorticoids; Humans; Immunosuppression Therapy; Immunos | 2009 |
Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from European Vasculitis Study Group clinical trials.
Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Azathioprine; Cyclophospham | 2011 |
UVA photosensitization of thiopurines and skin cancer in organ transplant recipients.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Mercaptopurine; Photosensitizing Agents; Skin Neopla | 2012 |
Safety of mycophenolate mofetil versus azathioprine in renal transplantation: a systematic review.
Topics: Azathioprine; Cytomegalovirus Infections; Follow-Up Studies; Humans; Immunosuppressive Agents; Incid | 2004 |
Reduction of immunosuppression for transplant-associated skin cancer: rationale and evidence of efficacy.
Topics: Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Organ Transplantation; P | 2005 |
Malignancy after transplantation.
Topics: Azathioprine; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Hepatitis, Viral, Hum | 2005 |
Induction of eruptive benign melanocytic naevi by immune suppressive agents, including biologicals.
Topics: Adult; Azathioprine; Drug Eruptions; Female; Humans; Immunocompromised Host; Immunologic Factors; Im | 2006 |
Azathioprine, UV light, and skin cancer in organ transplant patients--do we have an answer?
Topics: Azathioprine; Carcinoma, Squamous Cell; Humans; Immunosuppressive Agents; Kidney Transplantation; My | 2007 |
[Malignant tumors following renal transplantation].
Topics: Adrenal Cortex Hormones; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Humans; Immunosuppressi | 2007 |
Risk of nonmelanoma skin cancer with azathioprine use.
Topics: Azathioprine; Humans; Immunocompromised Host; Immunosuppressive Agents; Incidence; Inflammatory Bowe | 2008 |
Cutaneous reactions to rheumatological drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy | 1982 |
[Ki-1 lymphoma of the skin in a patient with Crohn's disease undergoing treatment with azathioprine].
Topics: Adult; Autoimmune Diseases; Azathioprine; Candidiasis; Crohn Disease; Humans; Hydronephrosis; Immuno | 2001 |
Cutaneous T-cell lymphoma in a cardiac transplant recipient.
Topics: Aged; Azathioprine; Cyclosporine; Heart Transplantation; Humans; Immunosuppression Therapy; Immunosu | 2001 |
Lymphoproliferative disorders after renal transplantation in patients receiving triple or quadruple immunosuppression.
Topics: Actuarial Analysis; Antilymphocyte Serum; Azathioprine; Carcinoma; Cyclosporine; Graft Survival; Her | 1992 |
Development of multiple carcinomas in a long term survivor of Wegener's granulomatosis treated with immunosuppressive drugs.
Topics: Adult; Azathioprine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Gran | 1989 |
Immunosuppressive and cytotoxic drugs in dermatology.
Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; | 1974 |
Immunosuppression and neoplasia. II. Is deficient immunesurveillance the only mechanism by which immunosuppression promotes neoplasia? A speculative review.
Topics: Animals; Animals, Newborn; Antilymphocyte Serum; Antimetabolites; Azathioprine; Carcinogens; Cell Di | 1973 |
The present status of chemotherapy in dermatology.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Azathioprine; Azauridine; Chemotherapy, Cancer, Region | 1972 |
5 trials available for azathioprine and Cancer of Skin
| Article | Year |
|---|---|
Conversion to sirolimus in kidney transplant recipients with squamous cell cancer and changes in immune phenotype.
Topics: Aged; Aged, 80 and over; Azathioprine; Calcineurin Inhibitors; Carcinoma, Squamous Cell; CD56 Antige | 2013 |
Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients.
Topics: Aged; Azathioprine; Calcineurin Inhibitors; Carcinoma, Squamous Cell; Creatinine; Female; Follow-Up | 2006 |
Incidence and type of cancer following the use of OKT3: a single center experience with 557 organ transplants.
Topics: Adenoma, Bile Duct; Age Factors; Azathioprine; Cyclosporine; Follow-Up Studies; Humans; Immunosuppre | 1993 |
Analysis of risk factors for cutaneous warts in renal transplant recipients.
Topics: Adolescent; Adult; Age Factors; Aged; Azathioprine; Body Mass Index; Cyclosporine; Female; Follow-Up | 1997 |
No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective.
Topics: Azathioprine; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Foll | 1992 |
134 other studies available for azathioprine and Cancer of Skin
| Article | Year |
|---|---|
Minimal risk of lymphoma and non-melanoma skin cancer despite long-term use of thiopurines in patients with inflammatory bowel disease: A longitudinal cohort analysis from northern India.
Topics: Azathioprine; Cohort Studies; Colitis, Ulcerative; Crohn Disease; Humans; India; Inflammatory Bowel | 2022 |
Cumulative thiopurine dosing and keratinocyte skin cancer in inflammatory bowel disease: a case-control study.
Topics: Azathioprine; Case-Control Studies; Humans; Inflammatory Bowel Diseases; Keratinocytes; Skin Neoplas | 2023 |
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients.
Topics: Adult; Age Factors; Australia; Azathioprine; Cohort Studies; Female; Humans; Immunosuppressive Agent | 2020 |
Eruptive melanocytic nevi during azathioprine therapy for antisynthetase syndrome.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Diagnosis, Differential; Female; Foot; Hand; Humans; | 2017 |
Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis.
Topics: Anus Neoplasms; Azathioprine; Colitis, Ulcerative; Colonoscopy; Female; Humans; Immunosuppressive Ag | 2017 |
Mogamulizumab-induced toxicoderma-like eruptions and autoimmune hepatitis successfully treated with azathioprine in adult T-cell leukaemia/lymphoma.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Azathioprine; Drug Eruptions; Female; Hepa | 2017 |
Azathioprine and risk of multiple keratinocyte cancers.
Topics: Aged; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cohort Studies; Female; Humans; | 2018 |
Altered epigenetic pathways and cell cycle dysregulation in healthy appearing skin of patients with koebnerized squamous cell carcinomas following skin surgery.
Topics: 5-Methylcytosine; Azathioprine; Carcinoma, Squamous Cell; Cell Cycle; Cyclin-Dependent Kinase Inhibi | 2018 |
Azathioprine to mycophenolate mofetil transition and risk of squamous cell carcinoma after lung transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Carcinoma, Squamous Cell; Child; Drug Substitution; Female; H | 2018 |
Inferior outcomes in immunocompromised Merkel cell carcinoma patients: Can they be overcome by the use of PD1/PDL1 inhibitors?
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic A | 2019 |
The genomic landscape of cutaneous SCC reveals drivers and a novel azathioprine associated mutational signature.
Topics: 3T3 Cells; Animals; Azathioprine; Biopsy; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line, | 2018 |
Skin lesions in organ transplant recipients: a study of 177 consecutive Brazilian patients.
Topics: Adolescent; Adult; Aged; Azathioprine; Brazil; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Chil | 2019 |
Mortality Associated With Development of Squamous Cell Cancer in Patients With Inflammatory Bowel Diseases Receiving Treatment With Thiopurines.
Topics: Aged; Azathioprine; Biopsy; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Immunosuppr | 2019 |
A rare lymphoproliferative disorder associated with immunomodulating therapy in Crohn's disease.
Topics: Azathioprine; Crohn Disease; Humans; Immunosuppressive Agents; Lymphomatoid Granulomatosis; Male; Mi | 2019 |
Azathioprine: friend or foe?
Topics: Azathioprine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Germ-Line Mutation; Humans; Immunosuppres | 2019 |
Gene expression profiling for cardiac rejection surveillance is not predictive of post-transplantation skin cancer.
Topics: Adult; Aged; Azathioprine; Carcinoma, Squamous Cell; Gene Expression; Gene Expression Profiling; Gra | 2013 |
Risk of non-melanoma skin cancer in myasthenia patients treated with azathioprine.
Topics: Azathioprine; Case-Control Studies; Community Health Planning; Confidence Intervals; Denmark; Female | 2014 |
Sebaceous carcinoma in patients receiving long-term immunosuppresive treatment: case report and literature review.
Topics: Aged, 80 and over; Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Fatal Outcome; Female; Huma | 2014 |
Analysis of malignancies in patients after heart transplantation with subsequent immunosuppressive therapy.
Topics: Adult; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Heart Transplantation; Humans; Immunos | 2015 |
Risk of merkel cell carcinoma after solid organ transplantation.
Topics: Adult; Aged; Azathioprine; Carcinoma, Merkel Cell; Cyclosporine; Female; Humans; Immunocompromised H | 2015 |
A case of esophageal adenocarcinoma on long-term rapamycin monotherapy.
Topics: Adenocarcinoma; Aged; Azathioprine; Biomarkers; Cyclosporine; Drug Substitution; Esophageal Neoplasm | 2015 |
Nonmelanoma skin cancer risk awareness in azathioprine-treated myasthenia gravis patients.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Counseling; Female; Humans; Immunosuppressive Agents; | 2015 |
Associations of Selected Cytokines Levels in Organ Transplant Recipients Without and With Malignant Skin Neoplasms.
Topics: Adult; Azathioprine; Case-Control Studies; Cyclosporine; Cytokines; Female; Glucocorticoids; Humans; | 2016 |
Preventive care for a 35-year-old woman with inflammatory bowel disease.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Contraindications; Early Detection of C | 2017 |
PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients.
Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Carcinoma, Basal Cell; Female; Graft Rejection; Humans | 2008 |
Azathioprine-induced microsatellite instability is not observed in skin carcinomas of organ transplant recipients.
Topics: Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; DNA, Neoplasm; Graft Rejection; Human | 2009 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma.
Topics: Adolescent; Adult; Aged; Azathioprine; Carcinoma, Squamous Cell; Case-Control Studies; Child; Cohort | 2010 |
Expression of DNA mismatch repair proteins and MSH2 polymorphisms in nonmelanoma skin cancers of organ transplant recipients.
Topics: Adaptor Proteins, Signal Transducing; Azathioprine; Base Pair Mismatch; Biomarkers, Tumor; Carcinoma | 2010 |
Transient iatrogenic immunodeficiency-related B-cell lymphoproliferative disorder of the skin in a patient with mycosis fungoides/Sézary syndrome.
Topics: Aged; Azathioprine; B-Lymphocytes; Epstein-Barr Virus Infections; Humans; Immunocompromised Host; Im | 2011 |
Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review.
Topics: Aged; Azathioprine; Head and Neck Neoplasms; Humans; Immunosuppression Therapy; Immunosuppressive Ag | 2010 |
Multiple cutaneous malignancies arising in a patient with Crohn disease treated with concomitant azathioprine and antitumour necrosis factor-alpha.
Topics: Adult; Azathioprine; Crohn Disease; Drug Therapy, Combination; Female; Humans; Immunosuppressive Age | 2010 |
Primary cutaneous lymphoma associated with Epstein-Barr virus and azathioprine therapy.
Topics: Aged; Azathioprine; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Lymphoma, Large B-Cell, | 2010 |
Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors.
Topics: Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Immunosuppressive Age | 2010 |
Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal.
Topics: Adolescent; Adult; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Drug Therapy, Combination; Ev | 2010 |
Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Female; Gastrointestinal Agents; Humans; Incidence; I | 2012 |
[Iatrogenic Kaposi's disease in Morocco in a non-transplant context].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antibodies, Viral; Azathioprine; Cyclophosphamide; Drug Therap | 2011 |
Cutaneous lymphoma in a patient with ulcerative colitis after immunosuppressive therapy.
Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Hodgkin D | 2011 |
Risk of non-melanoma skin cancer with thiopurine use in inflammatory bowel disease.
Topics: Anti-Inflammatory Agents; Azathioprine; Female; Gastrointestinal Agents; Humans; Inflammatory Bowel | 2012 |
Kaposi's sarcoma in patients with ulcerative colitis receiving immunosuppressive drugs: report of a case.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Colitis, Ulcerative; Female; Humans; Immunosuppressive | 2011 |
Spot diagnosis: eruptive melanocytic naevi during azathioprine therapy in Crohn's disease.
Topics: Azathioprine; Colonoscopy; Crohn Disease; Diagnosis, Differential; Dose-Response Relationship, Drug; | 2012 |
Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis.
Topics: Aged; Azathioprine; Colitis, Ulcerative; Female; Histiocytoma, Malignant Fibrous; Humans; Immunosupp | 2012 |
[Eruptive melanocytic nevi during azathioprine therapy in myasthenia gravis].
Topics: Azathioprine; Drug Eruptions; Humans; Immunosuppressive Agents; Male; Myasthenia Gravis; Nevus, Pigm | 2012 |
Cancer after heart transplant: implications for practice.
Topics: Azathioprine; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fatal Outcome; Glucocorticoids; H | 2012 |
Increased incidence of squamous cell carcinoma of the skin after long-term treatment with azathioprine in patients with auto-immune inflammatory rheumatic diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Squamous | 2014 |
Posttransplant primary cutaneous Ki-1 (CD30)+/CD56+ anaplastic large cell lymphoma.
Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; CD4-Positive T-Lym | 2004 |
Dermoscopic features of eruptive melanocytic naevi in an adult patient receiving immunosuppressive therapy for Crohn's disease.
Topics: Adult; Azathioprine; Crohn Disease; Dermoscopy; Female; Humans; Immunosuppression Therapy; Immunosup | 2005 |
Skin cancer in renal allograft recipients--experience in different ethnic groups residing in the same geographical region.
Topics: Adult; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Female; Humans; | 2005 |
Immunosuppression, skin cancer, and ultraviolet A radiation.
Topics: Azathioprine; Carcinoma, Squamous Cell; DNA Damage; Humans; Immunosuppression Therapy; Immunosuppres | 2005 |
The frequency and significance of thiopurine S-methyltransferase gene polymorphisms in azathioprine-treated renal transplant recipients.
Topics: Adolescent; Adult; Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Kidney Transplantat | 2006 |
Partial regression of Merkel cell carcinoma in response to withdrawal of azathioprine in an immunosuppression-induced case of metastatic Merkel cell carcinoma.
Topics: Azathioprine; Carcinoma, Merkel Cell; Fatal Outcome; Head and Neck Neoplasms; Humans; Immunocompromi | 2007 |
More epidermal p53 patches adjacent to skin carcinomas in renal transplant recipients than in immunocompetent patients: the role of azathioprine.
Topics: Adult; Aged; Animals; Azathioprine; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Clone | 2008 |
Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis.
Topics: Adult; Azathioprine; Breast Neoplasms; Central Nervous System Neoplasms; Cyclophosphamide; Digestive | 2008 |
Azathioprine treatment photosensitizes human skin to ultraviolet A radiation.
Topics: Adult; Azathioprine; Case-Control Studies; DNA Damage; Dose-Response Relationship, Radiation; Epider | 2008 |
Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer.
Topics: Azathioprine; Crossing Over, Genetic; Humans; Immunosuppression Therapy; Kidney Transplantation; Lym | 1983 |
Kidney failure or cancer. Should immunosuppression be continued in a transplant patient with malignant melanoma?
Topics: Adult; Azathioprine; Disease Susceptibility; Female; Glomerulonephritis; Graft Rejection; Humans; Im | 1984 |
Natural cell-mediated cytotoxicity and skin cancer in long-term renal allograft recipients.
Topics: Adolescent; Adult; Azathioprine; Child; Female; Humans; Immune Tolerance; Immunologic Surveillance; | 1984 |
[Cutaneous nodular Kaposi sarcoma following kidney transplantation and immunosuppression].
Topics: Adult; Azathioprine; Female; Humans; Immunosuppression Therapy; Kidney Failure, Chronic; Leukocyte C | 1984 |
Multicentric reticulohistiocytosis.
Topics: Arthritis; Azathioprine; Humans; Lymphatic Diseases; Male; Middle Aged; Myositis; Skin Neoplasms | 1984 |
Necrotizing vasculitis (angiitis) with granulomatosis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr | 1984 |
Kaposi's sarcoma in a renal allograft recipient under longterm immunosuppressive therapy.
Topics: Adult; Azathioprine; Humans; Immunosuppression Therapy; Kidney Transplantation; Male; Palatal Neopla | 1980 |
Verrucous carcinoma in a reanl transplant patient after long-term immunosuppression.
Topics: Adult; Azathioprine; Carcinoma, Papillary; Female; Graft Rejection; Humans; Immunosuppression Therap | 1980 |
Aggressive squamous cell carcinomas in organ transplant recipients.
Topics: Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Heart Transplantation; Humans; Immunosuppressi | 1995 |
Kaposi's sarcoma in renal transplant recipients: a case report.
Topics: Azathioprine; Cyclosporine; Female; Humans; Kidney Transplantation; Middle Aged; Palatal Neoplasms; | 1994 |
Transmission of Kaposi's sarcoma by solid organ donation.
Topics: Adult; Azathioprine; Cyclosporine; Disease Transmission, Infectious; Fatal Outcome; Female; Follow-U | 1994 |
Langerhans cells, immunomodulation and skin lesions. A quantitative, morphological and clinical study.
Topics: Adenosine Triphosphatases; Adjuvants, Immunologic; Adult; Aged; Aged, 80 and over; Animals; Antigens | 1993 |
Skin disease in immunosuppressed patients in relation to epidermal Langerhans' cells.
Topics: Azathioprine; Cyclosporine; Female; Humans; Immunosuppression Therapy; Kidney Transplantation; Lange | 1993 |
Clinical features and course of Kaposi's sarcoma in kidney transplant patients: report of 13 cases.
Topics: Adolescent; Adult; Azathioprine; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; | 1994 |
Squamous cell carcinoma in localized scleroderma following immunosuppressive therapy with azathioprine.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Humans; Male; Risk Factors; Scleroderma, Localized; S | 1993 |
The appearance of Kaposi sarcoma during corticosteroid therapy.
Topics: Adult; Aged; Autoimmune Diseases; Azathioprine; Betamethasone; Female; Humans; Lymphoproliferative D | 1993 |
Kaposi's sarcoma in kidney transplant recipients.
Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Humans; Incidence; Italy; | 1993 |
De novo malignancy emerges as a major cause of morbidity and late failure in renal transplantation.
Topics: Australia; Azathioprine; Cadaver; Cyclosporine; Female; Humans; Kidney Transplantation; Morbidity; N | 1993 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
Cancers in cyclosporine-treated vs azathioprine-treated patients.
Topics: Adult; Azathioprine; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Neoplasms | 1996 |
Kaposi sarcoma in a paediatric renal transplant recipient.
Topics: Adolescent; Azathioprine; Cyclosporine; Female; Humans; Immunosuppression Therapy; Kidney Transplant | 1996 |
Excess benign melanocytic naevi in renal transplant recipients.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Back; Buttocks; Case-Control Studies; Cyclosporine; F | 1997 |
Immunosuppression and risk of non-melanoma skin cancer in renal transplant recipients.
Topics: Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; | 1997 |
Kaposi's sarcoma during immunosuppressive therapy for atopic dermatitis.
Topics: Administration, Topical; Aged; Anti-Inflammatory Agents; Azathioprine; Betamethasone Valerate; CD4-P | 1997 |
Kaposi's sarcoma in renal-transplant recipients: experience at the Catholic University in Rome, 1988-1996.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Cyclosporine; Female; Follow-Up Studies; HIV Seronega | 1997 |
Vinorelbine therapy for Kaposi's sarcoma in a kidney transplant patient.
Topics: Antineoplastic Agents, Phytogenic; Azathioprine; Cyclosporine; Disease Progression; Follow-Up Studie | 1997 |
Kaposi's sarcoma as manifestation of immunosuppression in organ transplant recipients.
Topics: Anti-Inflammatory Agents; Azathioprine; Combined Modality Therapy; Cyclosporine; Graft Rejection; He | 1997 |
Kaposi's sarcoma associated with immunosuppression for bullous pemphigoid.
Topics: Aged; Aged, 80 and over; Azathioprine; Humans; Immunosuppressive Agents; Leg; Male; Pemphigoid, Bull | 1997 |
Study of malignancy among Egyptian kidney transplant recipients.
Topics: Azathioprine; Cyclosporine; Egypt; Female; Graft Survival; Humans; Immunosuppressive Agents; Inciden | 1997 |
Merkel cell carcinoma arising after therapeutic immunosuppression.
Topics: Aged; Azathioprine; Carcinoma, Merkel Cell; Cyclosporine; Female; Humans; Immunocompromised Host; Im | 1997 |
Recurrent Kaposi's sarcoma in a renal transplant recipient maintained on minimum doses of immunosuppression.
Topics: Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle A | 1998 |
Cardiac transplant-related cutaneous malignancies in an Australian recipient: immunosuppression, friend or foe?
Topics: Adult; Australia; Azathioprine; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cy | 1998 |
Iatrogenic Kaposi's sarcoma: HHV8 positivity persists but the tumors regress almost completely without immunosuppressive therapy.
Topics: Azathioprine; Cyclosporine; Herpesvirus 8, Human; Humans; Iatrogenic Disease; Immunosuppression Ther | 2000 |
Skin cancer in heart transplant recipients: risk factor analysis and relevance of immunosuppressive therapy.
Topics: Age Distribution; Azathioprine; Carcinoma, Squamous Cell; Comorbidity; Cyclosporine; Drug Therapy, C | 2000 |
Are heart transplant recipients more likely to develop skin cancer than kidney transplant recipients?
Topics: Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Drug Therapy, Combination; Heart Transplantati | 2000 |
Inflammatory bowel disease, azathioprine and skin cancer: case report and literature review.
Topics: Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Skin Neo | 2001 |
De novo Kaposi's sarcoma in renal transplantation. Case report and brief review.
Topics: Antibody Formation; Azathioprine; Bleomycin; Humans; Immunity, Cellular; Immunosuppression Therapy; | 1976 |
Neoplasia in kidney transplant recipients.
Topics: Adult; Azathioprine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Huma | 1975 |
Cancer and teratogenesis: infrequent occurrence after medical use of immunosuppressive drugs.
Topics: Abnormalities, Drug-Induced; Adult; Aged; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous C | 1977 |
Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs.
Topics: Adolescent; Adult; Aged; Australia; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Follow-Up | 1979 |
Accelerated induction of skin cancers by ultraviolet radiation in hairless mice treated with immunosuppressive agents.
Topics: Animals; Azathioprine; Carcinoma, Squamous Cell; Female; Mice; Mice, Nude; Prednisone; Skin Neoplasm | 1975 |
[Side effects in immunosuppressive therapy].
Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu | 1975 |
Human papillomavirus type 11 in multiple squamous cell carcinomas in a patient with subacute cutaneous lupus erythematosus.
Topics: Acute Disease; Azathioprine; Carcinoma, Squamous Cell; Cocarcinogenesis; Humans; Lupus Erythematosus | 1992 |
Skin cancer after renal transplantation: the causal role of azathioprine.
Topics: Adolescent; Adult; Aged; Azathioprine; Cocarcinogenesis; Female; Humans; Immunosuppression Therapy; | 1992 |
Angiomatosis with luminal cryoprotein deposition.
Topics: Aged; Angiomatosis; Azathioprine; Cryoglobulins; Humans; Immunoenzyme Techniques; Male; Middle Aged; | 1992 |
Living on borrowed time.
Topics: Attitude to Health; Azathioprine; Carcinoma, Squamous Cell; Heart Transplantation; Humans; Male; Nur | 1992 |
Cancer after transplantation in Catalonia.
Topics: Adult; Azathioprine; Cadaver; Cyclosporine; Female; Humans; Immunosuppression Therapy; Kidney Transp | 1992 |
The prevalence of skin disorders in renal allograft recipients receiving cyclosporin A compared with those receiving azathioprine.
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporins; Female; Humans; Kidney Transplantation; Male; M | 1990 |
Epidermal dysplasia and cyclosporine therapy in renal transplant patients: a comparison with azathioprine.
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclosporins; Drug Eruptions; Humans; Kidney Transplantation; | 1989 |
An exceptional 18-year follow-up after cardiac transplantation. How can malignancies occur during immunosuppressive therapy?
Topics: Adenocarcinoma, Papillary; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up | 1989 |
Enhancement of UV-induced skin carcinogenesis by azathioprine: role of photochemical sensitisation.
Topics: Animals; Azathioprine; Female; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Radiation-Sensiti | 1989 |
[Development of multiple precancerous conditions and malignant skin tumors in immunosuppressive therapy].
Topics: Azathioprine; Fluocortolone; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Trans | 1988 |
Resistant discoid lupus erythematosus of palms and soles: successful treatment with azathioprine.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Drug Resistance; Female; Foot Dermatoses; Hand Dermat | 1988 |
Kaposi's sarcoma after renal transplantation.
Topics: Adult; Azathioprine; Cyclosporins; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppres | 1987 |
Increased ultraviolet radiation-induced skin cancers in cyclosporine-treated mice.
Topics: Animals; Azathioprine; Cyclosporins; Female; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Ski | 1987 |
Effect of immunosuppressive agents and sunscreens on UV carcinogenesis in the hairless mouse.
Topics: 4-Aminobenzoic Acid; Animals; Antibody Formation; Azathioprine; Carcinoma in Situ; Carcinoma, Squamo | 1985 |
Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Drug Administration Schedule; Erythrocytes; Female; G | 1985 |
Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squa | 1985 |
Florid keratoacanthomas in a kidney transplant recipient. Case report.
Topics: Azathioprine; Carcinoma, Squamous Cell; Dactinomycin; Graft Rejection; Humans; Immunosuppression The | 1974 |
Skin cancer and immunosuppression.
Topics: Adult; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Immunosuppress | 1971 |
Cutaneous complications in immunosuppressed renal homograft recipients.
Topics: Acne Vulgaris; Adolescent; Adult; Alopecia; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous | 1974 |
Malignant tumours following immunosuppression in renal transplantation.
Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom | 1973 |
Kaposi Sarcoma complicating systemic lupus erythematosus treated with immunosuppression.
Topics: Adult; Azathioprine; Biopsy; Female; Fingers; Humans; Immunosuppressive Agents; Lupus Erythematosus, | 1974 |
Eight- to ten-year follow-up in early cases of renal homotransplantation.
Topics: Adolescent; Adult; Azathioprine; Blood Group Incompatibility; Carcinoma, Basal Cell; Carcinoma, Baso | 1973 |
Multiple cutaneous squamous cell carcinomas during immunosuppressive therapy.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Fluorouracil; Humans; Hyperplasia; Immunosuppressive | 1973 |
[Visceral Kaposi's sarcoma in a kidney recipient].
Topics: Abdominal Neoplasms; Azathioprine; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; P | 1973 |
Kaposi sarcoma in kidney transplant recipients.
Topics: Adult; Antilymphocyte Serum; Autopsy; Azathioprine; Brain Neoplasms; Cadaver; Female; Graft Rejectio | 1974 |
Premalignant and malignant skin tumours in immunosuppressed patients.
Topics: Adolescent; Adult; Aged; Azathioprine; Cadaver; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyc | 1974 |
Letter: Skin tumors with immunosuppressive therapy.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Kidney Transplantation; Prednisolone; Skin Neoplasms | 1974 |
Editorial: Focus on cutaneous host-defense failure in transplant recipients.
Topics: Azathioprine; Graft Rejection; Herpes Simplex; Herpes Zoster; Humans; Immunity, Cellular; Immunosupp | 1974 |
Skin tumours in immunosuppressed patients.
Topics: Adolescent; Adult; Allopurinol; Antineoplastic Agents; Azathioprine; Carcinoma, Basal Cell; Carcinom | 1973 |
Multiple dermatofibromas in patients with systemic lupus erythematosus on immunosuppressive therapy.
Topics: Adult; Azathioprine; Female; Fibroma; Humans; Lupus Erythematosus, Systemic; Neoplasms, Multiple Pri | 1973 |
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents; | 1973 |
Antimitotic drugs and aggressive squamous cell tumors.
Topics: Aged; Antineoplastic Agents; Azathioprine; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Kerat | 1972 |
Progressive development of chemical carcinogen-induced skin tumor and of transplantable carcinoma with an immunosuppressor.
Topics: Animals; Azathioprine; Carcinoma, Ehrlich Tumor; Gold; Gold Isotopes; Methylcholanthrene; Mice; Mono | 1971 |
[Practical use of immunosuppressive and cytostatic drugs in dermatological diseases].
Topics: Antineoplastic Agents; Azathioprine; Condylomata Acuminata; Fluorouracil; Humans; Immunosuppressive | 1970 |
Idiopathic thrombocytopenic purpura and Kaposi's sarcoma.
Topics: Aged; Azathioprine; Blood Cell Count; Blood Platelets; Female; Humans; Prednisolone; Purpura, Thromb | 1970 |
[Treatment of dermatologic lesions using immunosuppressive agents and cytostatics].
Topics: Antineoplastic Agents; Azathioprine; Dermatomyositis; Fluorouracil; Humans; Immunosuppressive Agents | 1970 |
[Exogenous and endogenous (hyperparathyroidism, Wegener's granulomatosis) poisonings].
Topics: Adenoma; Adult; Aged; Arsenic Poisoning; Autoimmune Diseases; Azathioprine; Child, Preschool; Diagno | 1967 |
Lack of Increased Risk of Lymphoma by Thiopurines or Biologics in Japanese Patients with Inflammatory Bowel Disease: A Large-Scale Administrative Database Analysis.
Topics: Adalimumab; Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colitis, Ulcerative; Crohn | 2020 |