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azathioprine and Cancer of Kidney

azathioprine has been researched along with Cancer of Kidney in 27 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"The patient was given a diagnosis of refractory anemia with excess of blasts in transformation (RAEB in T), and treated with idarubicin and cytosine arabinoside."2.40[Myelodysplastic syndrome (RAEB in T) developed in a renal allograft recipient]. ( Akiyama, M; Inaba, T; Katori, Y; Maki, K; Nakagawa, M; Sawada, K; Shimazaki, C; Shiraishi, J; Sudo, Y; Takada, O, 1998)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199014 (51.85)18.7374
1990's7 (25.93)18.2507
2000's6 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Deger, SM1
Mutluay, R1
Ebinc, FA1
Arinsoy, T1
Sindel, S1
Damaso, CR1
Oliveira, MF1
Massarani, SM1
Moussatché, N1
Wang, HB1
Hsieh, HH1
Chen, YT1
Chiang, CY1
Cheng, YT1
MARTIN, DC1
RUBINI, M1
ROSEN, VJ1
Nair, B1
Sukumar, S1
Poolari, GK1
Appu, T1
Cooke, MS1
Osborne, JE1
Singh, R1
Mistry, V1
Farmer, PB1
Evans, MD1
Hutchinson, PE1
Neuzillet, Y1
Karam, G1
Lechevallier, E1
Kleinclauss, F1
Dubernard, JM2
Cloix, P1
Tajra, LC1
Alduglihan, W1
Borson, F1
Lefrançois, N2
Martin, X1
Steinhäuslin, F1
Zanker, B1
Schirmacher, P1
Köhler, H1
Penn, I1
Fukuuchi, F1
Chapuis, F1
Gebuhrer, L1
Bosshard, S1
Touraine, JL1
Shiraishi, J1
Sudo, Y1
Katori, Y1
Akiyama, M1
Takada, O1
Maki, K1
Sawada, K1
Inaba, T1
Shimazaki, C1
Nakagawa, M1
Lye, WC1
Vathsala, A1
Lee, WT1
Leong, SO1
Sterioff, S1
Rios, CN1
Zachary, JB1
Williams, GM1
Sieber, SM1
Fishman, NH1
Belzer, FO2
Xerri, L1
Payan, MJ1
Choux, R1
Gros, N1
Hassoun, J1
Chamlian, A1
Blin, D1
Monties, JR1
Suranyi, MG1
Hall, BM1
Duggin, GG1
Horvath, JS1
Johnson, JR1
Sheil, AG1
Tiller, DJ1
Citterio, F1
Lauriola, L1
Nanni, G1
Vecchio, FM1
Magalini, SC1
Castagneto, M1
Murray, JE1
Wilson, RE1
Tilney, NL1
Merrill, JP1
Cooper, WC1
Birtch, AG1
Carpenter, CB1
Hager, EB1
Dammin, GJ1
Harrison, JH1
Lines, DR1
Casey, TP1
Schweizer, RT1
Kountz, SL1
DeLorimier, AA1
Birkeland, SA1
Kemp, E1
Ulrich, J1
Wüthrich, R1
Walker, D1
Gill, TJ1
Corson, JM1

Reviews

3 reviews available for azathioprine and Cancer of Kidney

ArticleYear
[MTOR inhibitors: from transplantation to oncology. AFU 2006 Transplantation Committee Review of the literature].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2007, Volume: 17, Issue:5

    Topics: Azathioprine; Humans; Kidney Neoplasms; Kidney Transplantation; Protein Kinase Inhibitors; Protein K

2007
[Myelodysplastic syndrome (RAEB in T) developed in a renal allograft recipient].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:8

    Topics: Anemia, Refractory, with Excess of Blasts; Azathioprine; Humans; Immunosuppressive Agents; Kidney Ne

1998
The action of antitumor agents: a double-edged sword?
    Medical and pediatric oncology, 1977, Volume: 3, Issue:2

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma;

1977

Trials

2 trials available for azathioprine and Cancer of Kidney

ArticleYear
Low-dose OKT3 is not effective in the treatment of steroid-resistant acute renal allograft rejections.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: Adult; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Rejection; Humans

1998
T cell presensitization in renal transplantation.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 1

    Topics: Azathioprine; Clinical Trials as Topic; Cyclosporins; Cytotoxicity Tests, Immunologic; False Negativ

1987

Other Studies

22 other studies available for azathioprine and Cancer of Kidney

ArticleYear
Renal cell carcinoma associated immunosuppressive therapy: a case report with Wegener's granulomatosis.
    Rheumatology international, 2009, Volume: 30, Issue:1

    Topics: Azathioprine; Carcinoma, Renal Cell; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, C

2009
Azathioprine inhibits vaccinia virus replication in both BSC-40 and RAG cell lines acting on different stages of virus cycle.
    Virology, 2002, Aug-15, Volume: 300, Issue:1

    Topics: Adenocarcinoma; Animals; Azathioprine; Cell Line; Chlorocebus aethiops; DNA Replication; Genes, Vira

2002
The outcome of post-transplant transitional cell carcinoma in 10 renal transplant recipients.
    Clinical transplantation, 2002, Volume: 16, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Transitional Cell; Cyclosporine; Female; Humans; Immunosuppressive A

2002
CADAVERIC RENAL HOMOTRANSPLANTATION WITH INADVERTENT TRANSPLANTATION OF CARCINOMA.
    JAMA, 1965, May-31, Volume: 192

    Topics: Antineoplastic Agents; Azathioprine; Carcinoma, Bronchogenic; Drug Therapy; Humans; Immunosuppressiv

1965
Azathioprine-induced squamous cell carcinoma of the kidney.
    Scandinavian journal of urology and nephrology, 2007, Volume: 41, Issue:2

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Humans; Immunosuppressive Agents; Kidney Neoplasms; M

2007
Evidence that oxidative stress is a risk factor for the development of squamous cell carcinoma in renal transplant patients.
    Free radical biology & medicine, 2007, Nov-01, Volume: 43, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Azathioprine; Carcinoma, Squamous Cell; Case-Control Studies; Deoxyguan

2007
Simultaneous adrenal gland and kidney allotransplantation after synchronous bilateral renal cell carcinoma: a case report.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Antilymphocyte Serum; Auto

1995
[After care following kidney transplantation].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1994, May-31, Volume: 83, Issue:22

    Topics: Adrenal Cortex Hormones; Azathioprine; Cardiovascular Diseases; Cyclosporine; Drug Therapy, Combinat

1994
[Bilateral kidney enlargement with kidney failure. Manifestation of primary extranodal B-cell lymphoma after long-term immunosuppression].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Feb-15, Volume: 89, Issue:2

    Topics: Azathioprine; Female; Humans; Hypertrophy; Kidney; Kidney Failure, Chronic; Kidney Neoplasms; Lupus

1994
Cancers in cyclosporine-treated vs azathioprine-treated patients.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adult; Azathioprine; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Neoplasms

1996
Comparative efficacy of prophylactic monoclonal (OKT3) and polyclonal antibodies (ATG) in immunologic high-risk renal transplant recipients.
    Transplantation proceedings, 1996, Volume: 28, Issue:5

    Topics: Antilymphocyte Serum; Azathioprine; Chi-Square Distribution; Cyclosporine; Cytomegalovirus Infection

1996
Neoplasia in kidney transplant recipients.
    American journal of surgery, 1975, Volume: 130, Issue:5

    Topics: Adult; Azathioprine; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Huma

1975
Resection of de novo lung cancer after renal transplantation.
    Transplantation, 1975, Volume: 20, Issue:3

    Topics: Azathioprine; Carcinoma, Bronchogenic; Humans; Immunosuppression Therapy; Kidney Neoplasms; Kidney T

1975
An exceptional 18-year follow-up after cardiac transplantation. How can malignancies occur during immunosuppressive therapy?
    Cancer, 1989, May-01, Volume: 63, Issue:9

    Topics: Adenocarcinoma, Papillary; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Follow-Up

1989
Polyclonal lymphoma confined to renal allograft: case report.
    Transplantation proceedings, 1987, Volume: 19, Issue:5

    Topics: Adult; Azathioprine; Cyclosporins; Humans; Immunosuppression Therapy; Kidney Neoplasms; Kidney Trans

1987
Five years' experience in renal transplantation with immunosuppressive drugs: survival, function, complications, and the role of lymphocyte depletion by thoracic duct fistula.
    Annals of surgery, 1968, Volume: 168, Issue:3

    Topics: Azaserine; Azathioprine; Cadaver; Carcinoma, Squamous Cell; Dactinomycin; Female; Fistula; Humans; H

1968
Nephrotic syndrome and nephroblastoma. Report of a case.
    The Journal of pediatrics, 1968, Volume: 72, Issue:2

    Topics: Azathioprine; Child, Preschool; Edema; Humans; Kidney Neoplasms; Male; Nephrosis; Prednisolone; Urog

1968
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
    Clinical and experimental immunology, 1968, Volume: 3, Issue:4

    Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis;

1968
Malignancy and immunosuppression. Renal homotransplantation in patients with primary renal neoplasms.
    Transplantation, 1972, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Adult; Azathioprine; Child, Preschool; Female; Humans; Immunosuppression Therapy; In

1972
Malignant tumours following immunosuppression in renal transplantation.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom

1973
Multiple sclerosis: reticulum cell sarcoma of the nervous system in a patient treated with immunosuppressive drugs.
    European neurology, 1974, Volume: 12, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Autopsy; Azathioprine; Biopsy, Needle; Brain Neoplasms; Cortison

1974
Leiomyosarcoma in a renal allograft recipient treated with immunosuppressive drugs.
    JAMA, 1971, Mar-29, Volume: 215, Issue:13

    Topics: Adenocarcinoma; Adult; Age Factors; Autopsy; Azathioprine; Histocompatibility; Humans; Immunosuppres

1971