azathioprine has been researched along with Cancer of Colon in 23 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Left breast cancer was diagnosed 9 years after the renal transplantation, then colon cancers and meningeal epidermal meningioma were diagnosed, 10 years and 12 years post-transplant, respectively." | 2.42 | Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case. ( Asahara, T; Dohi, K; Fukuda, Y; Hayamizu, K; Ikeda, S; Kataoka, T; Kitayama, T; Marubayashi, S; Ohdan, H; Okajima, M; Okimoto, T; Sugino, K; Tashiro, H, 2004) |
| "Ulcerative colitis (UC) associated with primary sclerosing cholangitis (PSC) is usually clinically mild." | 1.37 | Does the severity of primary sclerosing cholangitis influence the clinical course of associated ulcerative colitis? ( Burroughs, AK; Cholongitas, E; Hamilton, MI; Kalambokis, G; Marelli, L; Xirouchakis, E, 2011) |
| "Different hepatoma and colon carcinoma cell lines (HepG2, HuH7, Chang liver, LoVo, RKO, SW-48, SW-480) were grown in minimal essencial medium supplemented with 10% fetal bovine serum and 1% antibiotic/antimycotic solution and maintained in a humidified 37 °C incubator with 5% CO₂." | 1.37 | Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. ( Cuevas, EP; Díaz-Laviada, I; Fernández-Moreno, MD; Gisbert, JP; Guijarro, LG; Hernández-Breijo, B; Monserrat, J; Ramírez-Rubio, S; Román, ID; Vara, D, 2011) |
| "The development of colorectal cancer in ulcerative colitis is a function of disease duration, with the risk approaching 14% at 25 years." | 1.36 | Azathioprine, mucosal healing in ulcerative colitis, and the chemoprevention of colitic cancer: a clinical-practice-based forecast. ( Actis, GC; David, E; Pellicano, R; Sapino, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 7 (30.43) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Zerboni, G | 1 |
| Capurso, G | 1 |
| Pilozzi, E | 1 |
| Papi, C | 1 |
| Narula, N | 1 |
| Steinhart, AH | 1 |
| Actis, GC | 1 |
| Pellicano, R | 1 |
| David, E | 1 |
| Sapino, A | 1 |
| Da-Silva, N | 1 |
| Arasaradnam, R | 1 |
| Getliffe, K | 1 |
| Sung, E | 1 |
| Oo, Y | 1 |
| Nwokolo, C | 1 |
| Marelli, L | 1 |
| Xirouchakis, E | 1 |
| Kalambokis, G | 1 |
| Cholongitas, E | 1 |
| Hamilton, MI | 1 |
| Burroughs, AK | 1 |
| Hernández-Breijo, B | 1 |
| Monserrat, J | 1 |
| Ramírez-Rubio, S | 1 |
| Cuevas, EP | 1 |
| Vara, D | 1 |
| Díaz-Laviada, I | 1 |
| Fernández-Moreno, MD | 1 |
| Román, ID | 1 |
| Gisbert, JP | 1 |
| Guijarro, LG | 1 |
| Flynn, AD | 1 |
| Azar, JM | 1 |
| Chiorean, MV | 1 |
| Kitayama, T | 1 |
| Marubayashi, S | 1 |
| Hayamizu, K | 1 |
| Tashiro, H | 1 |
| Ohdan, H | 1 |
| Ikeda, S | 1 |
| Okimoto, T | 1 |
| Okajima, M | 1 |
| Kataoka, T | 1 |
| Sugino, K | 1 |
| Asahara, T | 1 |
| Fukuda, Y | 1 |
| Dohi, K | 1 |
| Sasaki, J | 1 |
| Kawamura, YJ | 1 |
| Konishi, F | 1 |
| Tosha, T | 1 |
| Hagenah, GC | 1 |
| Wündisch, T | 1 |
| Eckstein, E | 1 |
| Zimmermann, S | 1 |
| Holst, F | 1 |
| Grimm, W | 1 |
| Neubauer, A | 1 |
| Lohoff, M | 1 |
| Hallak, A | 1 |
| Baratz, M | 1 |
| Santo, M | 1 |
| Halpern, Z | 1 |
| Rabau, M | 1 |
| Werbin, N | 1 |
| Gilat, T | 1 |
| Rogers, AI | 1 |
| Symington, GR | 1 |
| Mackay, IR | 1 |
| Lambert, RP | 1 |
| McGeown, MG | 1 |
| Douglas, JF | 1 |
| Brown, WA | 1 |
| Donaldson, RA | 1 |
| Kennedy, JA | 1 |
| Loughridge, WG | 1 |
| Mehta, S | 1 |
| Hill, CM | 1 |
| Shorter, RG | 1 |
| Shephard, DA | 1 |
| Zelig, MP | 1 |
| Choi, PM | 1 |
| Puy-Montbrun, T | 1 |
| Pigot, F | 1 |
| Vuong, PN | 1 |
| Ganansia, R | 1 |
| Denis, J | 1 |
| Polson, RJ | 1 |
| Neuberger, J | 1 |
| Forman, D | 1 |
| Calne, R | 1 |
| Williams, R | 1 |
| Letsou, G | 1 |
| Ballantyne, GH | 1 |
| Zdon, IM | 1 |
| Cambria, RM | 1 |
| Modlin, IM | 1 |
| Brown, P | 1 |
| Kirsner, JB | 1 |
| Patterson, JF | 1 |
| Norton, RA | 1 |
| Schwartz, RS | 1 |
2 reviews available for azathioprine and Cancer of Colon
| Article | Year |
|---|---|
Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case.
Topics: Azathioprine; Breast Neoplasms; Carcinoma, Ductal, Breast; Colonic Neoplasms; Colonic Polyps; Drug T | 2004 |
Clinical progress in Crohn's disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anemia, Hypochromic; Anti-Bacterial Agents; Az | 1974 |
21 other studies available for azathioprine and Cancer of Colon
| Article | Year |
|---|---|
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Colonic small cell neuroendocrine carcinoma in a patient with long-standing ulcerative colitis treated with azathioprine.
Topics: Azathioprine; Carcinoma, Neuroendocrine; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; DNA-Bi | 2016 |
Preventive care for a 35-year-old woman with inflammatory bowel disease.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Contraindications; Early Detection of C | 2017 |
Azathioprine, mucosal healing in ulcerative colitis, and the chemoprevention of colitic cancer: a clinical-practice-based forecast.
Topics: Adult; Apoptosis; Azathioprine; Cohort Studies; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; | 2010 |
Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease.
Topics: Azathioprine; Biomarkers, Tumor; Chromosomal Instability; Colitis, Ulcerative; Colon; Colonic Neopla | 2010 |
Does the severity of primary sclerosing cholangitis influence the clinical course of associated ulcerative colitis?
Topics: Adult; Aged; Azathioprine; Cholangitis, Sclerosing; Colectomy; Colitis, Ulcerative; Colonic Neoplasm | 2011 |
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azathioprine; Buthionine Sulfoximine; Carcinoma | 2011 |
Spontaneous regression of colonic lymphoma following infliximab and azathioprine withdrawal in patients with Crohn's disease.
Topics: Adult; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Colonic | 2013 |
Colitic cancer developed after introduction of azathioprine.
Topics: Adenocarcinoma; Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; Fatal Outc | 2004 |
[Sepsis-like disease in an immunocompromised patient with a travel history to Mallorca].
Topics: Adult; Animals; Azathioprine; Biopsy; Bone Marrow; Colectomy; Colitis, Ulcerative; Colon; Colonic Ne | 2007 |
Ileitis after colectomy for ulcerative colitis or carcinoma.
Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; | 1994 |
Managing ulcerative colitis.
Topics: Azathioprine; Carcinoma; Colitis, Ulcerative; Colonic Neoplasms; Humans; Prednisone; Sulfasalazine | 1976 |
Cancer and teratogenesis: infrequent occurrence after medical use of immunosuppressive drugs.
Topics: Abnormalities, Drug-Induced; Adult; Aged; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous C | 1977 |
Low dose steroid from the day following renal transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Central Nervous System Diseases; Child; Colonic Neoplasms; Do | 1979 |
Frontiers in inflammatory bowel disease. The proceedings of a conference sponsored by the McReynolds Foundation. Part II.
Topics: Adenocarcinoma; Arthritis; Azathioprine; Child; Chronic Disease; Colitis, Ulcerative; Colonic Neopla | 1975 |
Azathioprine or 6-mercaptopurine therapy and colon carcinoma in Crohn's disease.
Topics: Adult; Azathioprine; Carcinoma; Colonic Neoplasms; Crohn Disease; Humans; Mercaptopurine | 1992 |
Kaposi's sarcoma of the colon in a young HIV-negative woman with Crohn's disease.
Topics: Adult; Azathioprine; Colonic Neoplasms; Crohn Disease; Female; HIV Seropositivity; Humans; Sarcoma, | 1991 |
De novo malignancies after liver transplantation.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Azathioprine; Child; Colonic Neoplasms; Cyclosporins; Dysge | 1988 |
Rectal carcinoma in a renal transplant patient. Long-term complication of immunosuppression?
Topics: Adenocarcinoma; Azathioprine; Barium Sulfate; Colonic Neoplasms; Enema; Humans; Immunosuppressive Ag | 1986 |
The challenges of ulcerative colitis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Azathioprine; Blood Transfusion; | 1971 |
Azathioprine treatment of ulcerative colitis, granulomatous colitis and regional enteritis.
Topics: Adolescent; Adult; Aged; Azathioprine; Carcinoma; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; | 1971 |