Page last updated: 2024-10-23

azathioprine and Cancer of Cervix

azathioprine has been researched along with Cancer of Cervix in 17 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Efficacy and safety of azathioprine in 'high' and 'low' dose regimens in rheumatoid arthritis (RA), both in short-term studies and in follow-up over 40 months, have previously been shown."7.66Long-term effects of azathioprine in rheumatoid arthritis. ( Able, T; Norman, CS; Smythe, HA; Travis, C; Urowitz, MB, 1982)
"Efficacy and safety of azathioprine in 'high' and 'low' dose regimens in rheumatoid arthritis (RA), both in short-term studies and in follow-up over 40 months, have previously been shown."3.66Long-term effects of azathioprine in rheumatoid arthritis. ( Able, T; Norman, CS; Smythe, HA; Travis, C; Urowitz, MB, 1982)
"One patient developed Kaposi sarcoma of the cervix."2.40[Pregnancy after heart and heart-lung transplantation. Apropos of 10 cases and review of the literature]. ( Fernandez, H; Frydman, R; Troché, V; Ville, Y, 1997)
"The frequency of cancer-associated mortality was 11% that was 2% of the total lupus population."1.33[The occurrence of malignancies in a Hungarian lupus population]. ( Kiss, E; Szegedi, G; Szekanecz, E; Tarr, T; Zeher, M, 2006)
"Autopsy revealed that the cervical cancer was the primary origin of the liver tumors."1.30[Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura]. ( Kariya, K; Kawamura, S; Munakata, A; Nakahata, R; Takami, H; Tamai, Y; Tsushima, K; Yoshimura, T, 1999)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19907 (41.18)18.7374
1990's5 (29.41)18.2507
2000's3 (17.65)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Fanouriakis, A1
Tziolos, N1
Bertsias, G1
Boumpas, DT1
Narula, N1
Steinhart, AH1
Alvarez Delgado, A1
Pérez García, ML1
Fradejas Salazar, PM1
de la Coba Ortíz, C1
Rodríguez Pérez, A1
Ognenovski, VM1
Marder, W1
Somers, EC1
Johnston, CM1
Farrehi, JG1
Selvaggi, SM1
McCune, WJ1
Tarr, T1
Szekanecz, E1
Zeher, M1
Szegedi, G1
Kiss, E1
Urowitz, MB1
Smythe, HA1
Able, T1
Norman, CS1
Travis, C1
Fish, EN1
Tobin, SM1
Cooter, NB1
Papsin, FR1
Nyberg, G1
Eriksson, O1
Westberg, NG1
Theobald, I1
Limberg, B1
Magener, A1
Kauffmann, GW1
Amato, MP1
Pracucci, G1
Ponziani, G1
Siracusa, G1
Fratiglioni, L1
Amaducci, L1
Penn, I1
Troché, V1
Ville, Y1
Frydman, R1
Fernandez, H1
Yoshimura, T1
Tamai, Y1
Takami, H1
Kariya, K1
Nakahata, R1
Tsushima, K1
Munakata, A1
Kawamura, S1
Leckie, GB1
Cotton, RE1
Norfleet, RG1
Sampson, CE1
Donohue, LR1
Neuberg, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033]120 participants (Anticipated)Interventional2022-08-15Enrolling by invitation
Multicenter Clinical Trial Evaluating the Immunological Response of Vaccination Against Infection by Human Papillomavirus (HPV) 6, 11, 16, 18 in Girls Receiving Immunosuppressive Therapy.[NCT01687192]Phase 237 participants (Anticipated)Interventional2012-10-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for azathioprine and Cancer of Cervix

ArticleYear
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc

2021
[Pregnancy after heart and heart-lung transplantation. Apropos of 10 cases and review of the literature].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1997, Volume: 26, Issue:6

    Topics: Adrenal Cortex Hormones; Azathioprine; Birth Weight; Cardiomyopathy, Hypertrophic; Cesarean Section;

1997
Colposcopic and cytologic evaluation of women undergoing immunosuppressive therapy.
    The Journal of reproductive medicine, 1974, Volume: 12, Issue:5

    Topics: Antigens, Neoplasm; Azathioprine; Carcinoma in Situ; Carcinoma, Squamous Cell; Colposcopy; Female; G

1974

Other Studies

14 other studies available for azathioprine and Cancer of Cervix

ArticleYear
Preventive care for a 35-year-old woman with inflammatory bowel disease.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017, Feb-13, Volume: 189, Issue:6

    Topics: Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Contraindications; Early Detection of C

2017
[Invasive cancer of the cervix in a patient undergoing chronic treatment with 6-mercaptopurine for Crohns disease].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Aged; Azathioprine; Carcinoma, Squamous Cell; Crohn Disease; Fatal Outcome; Female; Humans; Immunosu

2003
Increased incidence of cervical intraepithelial neoplasia in women with systemic lupus erythematosus treated with intravenous cyclophosphamide.
    The Journal of rheumatology, 2004, Volume: 31, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Azathioprine; Cyclophosphamide; Female; Follo

2004
[The occurrence of malignancies in a Hungarian lupus population].
    Orvosi hetilap, 2006, Nov-19, Volume: 147, Issue:46

    Topics: Adult; Aged; Azathioprine; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Female; Gastroin

2006
Long-term effects of azathioprine in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Adenocarcinoma; alpha-Fetoproteins; Arthritis, Rheumatoid; Azathioprine; Chromosome Aberrations; Dos

1982
Update on the relation of herpesvirus hominis type II to carcinoma of the cervix.
    Obstetrics and gynecology, 1982, Volume: 59, Issue:2

    Topics: Animals; Azathioprine; Cervix Uteri; Diethylstilbestrol; Female; Herpes Genitalis; Male; Rats; Rats,

1982
Increased incidence of cervical atypia in women with systemic lupus erythematosus treated with chemotherapy.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:5

    Topics: Adult; Aged; Azathioprine; Cervix Uteri; Female; Humans; Lupus Erythematosus, Systemic; Middle Aged;

1981
[Fulminant, fatal respiratory insufficiency in long-term immunosuppression after kidney transplantation].
    Der Radiologe, 1995, Volume: 35, Issue:3

    Topics: Adult; Azathioprine; Fatal Outcome; Female; Humans; Immunologic Deficiency Syndromes; Kidney Transpl

1995
Long-term safety of azathioprine therapy in multiple sclerosis.
    Neurology, 1993, Volume: 43, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci

1993
Cancers in cyclosporine-treated vs azathioprine-treated patients.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adult; Azathioprine; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Neoplasms

1996
[Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1999, Volume: 40, Issue:2

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Disease Progression; Female; Humans; Immunosuppressiv

1999
Simultaneous in situ carcinoma of the cervix, vulva and perineum after immunosuppressive therapy for renal transplantation.
    British journal of obstetrics and gynaecology, 1977, Volume: 84, Issue:2

    Topics: Adult; Azathioprine; Carcinoma in Situ; Female; Humans; Immunosuppression Therapy; Kidney Transplant

1977
Carcinoma of the cervix after treatment with prednisone and azathioprine for chronic active hepatitis.
    The American journal of gastroenterology, 1978, Volume: 70, Issue:4

    Topics: Adult; Azathioprine; Carcinoma in Situ; Chronic Disease; Female; Hepatitis; Humans; Immunosuppressio

1978
Immunosuppression and plasmocytoma of the cervix.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1974, Volume: 81, Issue:2

    Topics: Adult; Azathioprine; Diabetes Complications; Female; Furosemide; Humans; Immunosuppression Therapy;

1974