azathioprine has been researched along with Cancer, Second Primary in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To our knowledge this is the first reported case of LYG related to azathioprine therapy in Crohn disease." | 7.80 | Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. ( Belletrutti, PJ; Connors, W; Griffiths, C; Patel, J, 2014) |
| "The risk of breast cancer recurrence in patients who received methotrexate, thiopurine, or anti-TNF therapy was not statistically significantly increased, although we cannot rule out a 2-fold or greater increased risk in those treated with thiopurines." | 3.83 | Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study. ( Boursi, B; Brensinger, CM; Chen, L; Clark, AS; Curtis, JR; Lewis, JD; Mamtani, R; Osterman, MT; Scott, FI; Xie, F; Yun, H, 2016) |
| " To our knowledge this is the first reported case of LYG related to azathioprine therapy in Crohn disease." | 3.80 | Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. ( Belletrutti, PJ; Connors, W; Griffiths, C; Patel, J, 2014) |
| "Endoscopic examination revealed esophageal cancer." | 1.29 | [Chronic myelomonocytic leukemia and esophageal cancer developed in a renal allograft recipient]. ( Fujita, N; Goto, H; Inaba, T; Itoh, K; Misawa, S; Murakami, S; Nakagawa, M; Oku, N; Shima, T; Shimazaki, C, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connors, W | 1 |
| Griffiths, C | 1 |
| Patel, J | 1 |
| Belletrutti, PJ | 1 |
| Chien, SH | 1 |
| Liu, CJ | 1 |
| Hong, YC | 1 |
| Teng, CJ | 1 |
| Hu, YW | 1 |
| Shen, CC | 1 |
| Ku, FC | 1 |
| Chen, SC | 1 |
| Yeh, CM | 1 |
| Chiou, TJ | 1 |
| Gau, JP | 1 |
| Tzeng, CH | 1 |
| Satish, R | 1 |
| Rout, P | 1 |
| Alexander, B | 1 |
| Canha, C | 1 |
| Ferreira, R | 1 |
| Rovira, J | 1 |
| Moya-Rull, D | 1 |
| Castells, A | 1 |
| Diekmann, F | 1 |
| Oppenheimer, F | 1 |
| Campistol, JM | 1 |
| Revuelta, I | 1 |
| Mamtani, R | 1 |
| Clark, AS | 1 |
| Scott, FI | 1 |
| Brensinger, CM | 1 |
| Boursi, B | 1 |
| Chen, L | 1 |
| Xie, F | 1 |
| Yun, H | 1 |
| Osterman, MT | 1 |
| Curtis, JR | 1 |
| Lewis, JD | 1 |
| Wang, HB | 1 |
| Hsieh, HH | 1 |
| Chen, YT | 1 |
| Chiang, CY | 1 |
| Cheng, YT | 1 |
| Mok, CC | 1 |
| Kwong, YL | 1 |
| Lau, CS | 1 |
| Shima, T | 1 |
| Oku, N | 1 |
| Goto, H | 1 |
| Inaba, T | 1 |
| Murakami, S | 1 |
| Itoh, K | 1 |
| Fujita, N | 1 |
| Shimazaki, C | 1 |
| Misawa, S | 1 |
| Nakagawa, M | 1 |
8 other studies available for azathioprine and Cancer, Second Primary
| Article | Year |
|---|---|
Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease.
Topics: Adult; Azathioprine; Brain Neoplasms; Crohn Disease; Female; Humans; Immunocompromised Host; Immunos | 2014 |
Use of azathioprine for graft-vs-host disease is the major risk for development of secondary malignancies after haematopoietic stem cell transplantation: a nationwide population-based study.
Topics: Adult; Azathioprine; Cohort Studies; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transpla | 2015 |
Double primary carcinoma in a renal allograft recipient.
Topics: Allografts; Azathioprine; Biopsy; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Papillary; | 2014 |
A case of esophageal adenocarcinoma on long-term rapamycin monotherapy.
Topics: Adenocarcinoma; Aged; Azathioprine; Biomarkers; Cyclosporine; Drug Substitution; Esophageal Neoplasm | 2015 |
Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study.
Topics: Adalimumab; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Cohort S | 2016 |
The outcome of post-transplant transitional cell carcinoma in 10 renal transplant recipients.
Topics: Adult; Azathioprine; Carcinoma, Transitional Cell; Cyclosporine; Female; Humans; Immunosuppressive A | 2002 |
Secondary acute myeloid leukaemia with 7q- complicating azathioprine treatment for rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Leukemia, Myeloid, Acute; Neoplasms, Seco | 1995 |
[Chronic myelomonocytic leukemia and esophageal cancer developed in a renal allograft recipient].
Topics: Azathioprine; Carcinoma, Squamous Cell; Esophageal Neoplasms; Humans; Immunosuppression Therapy; Kid | 1993 |