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azathioprine and Bullous Dermatoses

azathioprine has been researched along with Bullous Dermatoses in 32 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Acute generalized exanthematous pustulosis (AGEP) is identified by several characteristic features."5.34Acute generalized exanthematous pustulosis associated with azathioprine hypersensitivity. ( Elston, GE; Harman, KE; Johnston, GA; Mortimer, NJ, 2007)
"Severe cases of pemphigus vulgaris should be treated with prednisone in high dosage (180-360 mg daily)."3.67[Therapy of pemphigus and pemphigoid]. ( Schaumburg-Lever, G, 1986)
"Most reports on APF suggest systemic lupus erythematosus (SLE) as the major immunological associated disorder but the association with autoimmune hepatitis (AH) has not been previously documented."2.49Amicrobial pustulosis of the folds associated with autoimmune disorders: systemic lupus erythematosus case series and first report on the association with autoimmune hepatitis. ( Charli-Joseph, Y; Fernández Sánchez, M; Méndez-Flores, S; Orozco-Topete, R; Saeb-Lima, M, 2013)
"Acute generalized exanthematous pustulosis (AGEP) is identified by several characteristic features."1.34Acute generalized exanthematous pustulosis associated with azathioprine hypersensitivity. ( Elston, GE; Harman, KE; Johnston, GA; Mortimer, NJ, 2007)
"Bullous systemic lupus erythematosus is a rare disease associated with subepidermal blistering and, in most cases, severe systemic manifestations."1.32[Bullous systemic lupus erythematosus]. ( Bacman, D; Kuhn, A; Megahed, M; Ostendorf, B; Ruzicka, T; Schneider, M, 2004)
"We found that untreated ocular cicatricial pemphigoid has a variable course and does not necessarily progress."1.27Immunosuppressive therapy in ocular cicatricial pemphigoid. ( Brown, SI; Mondino, BJ, 1983)
"Bullous pemphigoid is an autoimmune bullous dermatosis that can be preceded by a prodromal phase, usually lasting weeks to months, during which the cutaneous changes are dermatitic rather than bullous."1.27The prodrome of bullous pemphigoid. ( Amato, DA; Silverstein, J; Zitelli, J, 1988)
"1."1.26[Disseminated cicatricial pemphigoid]. ( Braun-Falco, O; Ponce, E; Wolff, HH, 1981)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's5 (15.63)18.2507
2000's6 (18.75)29.6817
2010's3 (9.38)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Kaae, J1
Bech, R1
Taudorf, EH1
Beck, S1
Vestergaard, C1
Ring, HC1
Jemec, GB1
Méndez-Flores, S1
Charli-Joseph, Y1
Saeb-Lima, M1
Orozco-Topete, R1
Fernández Sánchez, M1
Comfere, NI1
Ikediobi, ON1
Peters, MS1
el-Azhary, RA1
Gibson, LE1
Wolverton, SE1
Lateef, A1
Tan, KB1
Lau, TC1
Irioka, T1
Mizusawa, H1
Bacman, D1
Ostendorf, B1
Megahed, M1
Ruzicka, T1
Schneider, M1
Kuhn, A1
Reynaert, S1
Black, MM2
Elston, GE1
Johnston, GA1
Mortimer, NJ1
Harman, KE1
Lewis, MA1
Yaqoob, NA1
Emanuel, C1
Potts, AJ1
Mondino, BJ1
Brown, SI1
Levene, GM1
Braun-Falco, O1
Wolff, HH1
Ponce, E1
Olmos, L1
de Diego, V1
Ahmed, AR3
Moy, R1
Foster, CS1
Wilson, LA1
Ekins, MB1
Anstey, A2
Whittaker, SJ1
Bhogal, BS1
Hermanns-Lê, T1
Piérard, GE1
Maize, JC1
Provost, TT1
Burton, JL2
Harman, RM1
Peachey, RD2
Warin, RP2
Harman, RR1
Thomson, J1
Lang, W1
Craig, JA1
Collison, DW1
Dahlberg, PJ1
Hogan, JD1
Bandemir, W1
Krëger, E1
Prasad, KK1
Chen, L1
Jeffes, EW1
Amato, DA1
Silverstein, J1
Zitelli, J1
Prystowsky, JH1
Finkel, L1
Tar, L1
Jegasothy, B1
Schaumburg-Lever, G1
Pawlofsky, C1
Simon, M1
Fartasch, M1
Keller, J1

Reviews

7 reviews available for azathioprine and Bullous Dermatoses

ArticleYear
[Bullous skin diseases].
    Ugeskrift for laeger, 2022, 10-10, Volume: 184, Issue:41

    Topics: Autoimmune Diseases; Azathioprine; Glucocorticoids; Humans; Methotrexate; Pemphigus; Rituximab; Skin

2022
Amicrobial pustulosis of the folds associated with autoimmune disorders: systemic lupus erythematosus case series and first report on the association with autoimmune hepatitis.
    Dermatology (Basel, Switzerland), 2013, Volume: 226, Issue:1

    Topics: Adult; Antirheumatic Agents; Azathioprine; Chloroquine; Dapsone; Diagnosis, Differential; Drug Thera

2013
Pharmacogenetics in dermatology: a patient-centered update.
    International journal of dermatology, 2013, Volume: 52, Issue:8

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineo

2013
Treating immunobullous diseases: an update.
    Dermatology nursing, 2004, Volume: 16, Issue:1

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Autoimmune

2004
The treatment of pemphigus and pemphigoid.
    Clinical and experimental dermatology, 1982, Volume: 7, Issue:6

    Topics: Aged; Azathioprine; Cosyntropin; Drug Therapy, Combination; Humans; Methylprednisolone; Pemphigoid,

1982
Azathioprine.
    International journal of dermatology, 1981, Volume: 20, Issue:7

    Topics: Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Colitis, Ulcerative; Crohn Diseas

1981
Azathioprine in dermatology: a review in the light of advances in understanding methylation pharmacogenetics.
    Journal of the Royal Society of Medicine, 1995, Volume: 88, Issue:3

    Topics: Azathioprine; Counseling; Humans; Mercaptopurine; Methylation; Methyltransferases; Skin Diseases; Sk

1995

Trials

2 trials available for azathioprine and Bullous Dermatoses

ArticleYear
A controlled trial of azathioprine in the treatment of pemphigoid [proceedings].
    The British journal of dermatology, 1978, Volume: 99, Issue:Suppl 16

    Topics: Aged; Azathioprine; Clinical Trials as Topic; Female; Humans; Male; Prednisone; Skin Diseases, Vesic

1978
Azathioprine plus prednisone in treatment of pemphigoid.
    British medical journal, 1978, Oct-28, Volume: 2, Issue:6146

    Topics: Aged; Azathioprine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Follow-Up Studies;

1978

Other Studies

23 other studies available for azathioprine and Bullous Dermatoses

ArticleYear
Optimizing clinical use of azathioprine with newer pharmacogenetic data.
    Archives of dermatology, 2009, Volume: 145, Issue:6

    Topics: Azathioprine; Dermatitis, Atopic; Dose-Response Relationship, Drug; Drug Administration Schedule; Fe

2009
Acute generalized exanthematous pustulosis and toxic epidermal necrolysis induced by hydroxychloroquine.
    Clinical rheumatology, 2009, Volume: 28, Issue:12

    Topics: Aged; Antirheumatic Agents; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Thera

2009
Hemorrhagic bulla in Churg-Strauss syndrome.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:19

    Topics: Adrenal Cortex Hormones; Azathioprine; Churg-Strauss Syndrome; Hemorrhage; Humans; Leg; Male; Middle

2011
[Bullous systemic lupus erythematosus].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Dermatologic Agents; Fluorescent Antibody Technique,

2004
Acute generalized exanthematous pustulosis associated with azathioprine hypersensitivity.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:1

    Topics: Azathioprine; Drug Eruptions; Exanthema; Female; Humans; Immunosuppressive Agents; Middle Aged; Skin

2007
Successful treatment of oral linear IgA disease using mycophenolate.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007, Volume: 103, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Female; Fluorescent Antibody

2007
Immunosuppressive therapy in ocular cicatricial pemphigoid.
    American journal of ophthalmology, 1983, Volume: 96, Issue:4

    Topics: Aged; Azathioprine; Cyclophosphamide; Eye Diseases; Female; Humans; Immunosuppressive Agents; Male;

1983
[Disseminated cicatricial pemphigoid].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1981, Volume: 32, Issue:5

    Topics: Aged; Azathioprine; Basement Membrane; Complement C3; Humans; Immunoglobulin M; Male; Pemphigoid, Be

1981
[Psoriasis and pemphigoid (author's transl)].
    Dermatologica, 1981, Volume: 163, Issue:1

    Topics: Adult; Aged; Azathioprine; Female; Humans; Male; Methylprednisolone; Middle Aged; Pemphigoid, Bullou

1981
Immunosuppressive therapy for progressive ocular cicatricial pemphigoid.
    Ophthalmology, 1982, Volume: 89, Issue:4

    Topics: Adult; Aged; Azathioprine; Cicatrix; Conjunctival Diseases; Corneal Diseases; Cyclophosphamide; Drug

1982
Acquired immunobullous disease: a cutaneous manifestation of IgM macroglobulinaemia.
    The British journal of dermatology, 1996, Volume: 135, Issue:2

    Topics: Azathioprine; Humans; Immunoglobulin M; Immunohistochemistry; Male; Middle Aged; Prednisolone; Skin;

1996
Management of immunobullous disorders: the clinical significance of interindividual variation in azathioprine metabolism.
    Clinical and experimental dermatology, 1996, Volume: 21, Issue:3

    Topics: Autoimmune Diseases; Azathioprine; Humans; Immunosuppressive Agents; Methyltransferases; Skin Diseas

1996
Azathioprine-induced skin peeling syndrome.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:2

    Topics: Azathioprine; Cytoplasm; Desmosomes; Drug Eruptions; Female; Follow-Up Studies; Humans; Immunosuppre

1997
Bullous pemphigoid. Clinical and immunologic follow-up after successful therapy.
    Archives of dermatology, 1977, Volume: 113, Issue:8

    Topics: Adult; Aged; Azathioprine; Basement Membrane; Complement C3; Drug Therapy, Combination; Female; Fluo

1977
Deafness complicating mucous membrane pemphigoid: a case report.
    The British journal of dermatology, 1975, Volume: 93, Issue:3

    Topics: Azathioprine; Deafness; Ear, Middle; Humans; Male; Middle Aged; Mucous Membrane; Prednisolone; Skin

1975
Azathioprine hypersensitivity in bullous pemphigoid.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:1

    Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Fever; Headache; Humans; Pemphigoid, Bullous; Ski

1990
[Therapeutic use of plasmapheresis in a patient with bullous pemphigoid].
    Vestnik dermatologii i venerologii, 1989, Issue:2

    Topics: Aged; Aged, 80 and over; Azathioprine; Humans; Male; Pemphigoid, Bullous; Plasmapheresis; Skin Disea

1989
Anesthetic management of a patient with bullous pemphigoid.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:4

    Topics: Anesthesia, Spinal; Azathioprine; Female; Humans; Injections, Spinal; Middle Aged; Pemphigoid, Bullo

1989
Adjuvant therapy of bullous pemphigoid with dapsone.
    Clinical and experimental dermatology, 1989, Volume: 14, Issue:2

    Topics: Adult; Aged; Azathioprine; Dapsone; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Pe

1989
The prodrome of bullous pemphigoid.
    International journal of dermatology, 1988, Volume: 27, Issue:8

    Topics: Aged; Azathioprine; Biopsy; Dermatitis; Female; Fluorescent Antibody Technique; Humans; Middle Aged;

1988
Bullous eruption in a woman with lupus erythematosus. Bullous systemic lupus erythematosus (SLE)
    Archives of dermatology, 1988, Volume: 124, Issue:4

    Topics: Adult; Azathioprine; Dapsone; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Hum

1988
[Therapy of pemphigus and pemphigoid].
    Zeitschrift fur Hautkrankheiten, 1986, Jun-01, Volume: 61, Issue:11

    Topics: Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Humans; Methotrexate; Pemphigoid, Bullous

1986
Disseminated cicatricial pemphigoid.
    Dermatologica, 1985, Volume: 171, Issue:4

    Topics: Azathioprine; Drug Therapy, Combination; Humans; Male; Middle Aged; Pemphigoid, Benign Mucous Membra

1985