azathioprine has been researched along with Breast Cancer in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The risk of breast cancer recurrence in patients who received methotrexate, thiopurine, or anti-TNF therapy was not statistically significantly increased, although we cannot rule out a 2-fold or greater increased risk in those treated with thiopurines." | 3.83 | Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study. ( Boursi, B; Brensinger, CM; Chen, L; Clark, AS; Curtis, JR; Lewis, JD; Mamtani, R; Osterman, MT; Scott, FI; Xie, F; Yun, H, 2016) |
| " But fibroadenomas may be seen as a result of exposure to cyclosporine (CyA)." | 3.72 | Report of a renal transplanted patient with fibroadenoma occurring in a short time. ( Balal, M; Karayaylali, I; Paydas, S; Seyrek, N, 2003) |
| "Left breast cancer was diagnosed 9 years after the renal transplantation, then colon cancers and meningeal epidermal meningioma were diagnosed, 10 years and 12 years post-transplant, respectively." | 2.42 | Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case. ( Asahara, T; Dohi, K; Fukuda, Y; Hayamizu, K; Ikeda, S; Kataoka, T; Kitayama, T; Marubayashi, S; Ohdan, H; Okajima, M; Okimoto, T; Sugino, K; Tashiro, H, 2004) |
| "Azathioprine (AZA) treatment in transplant or autoimmune patients and subsequent appearance squamous cell carcinomas at various sites, particularly skin and cervix, has shown a close relationship." | 1.38 | [A case of squamous cell carcinoma of the breast in a patient with Crohn's disease taking azathioprine]. ( Cho, JY; Heo, SW; Ju, DU; Kim, EJ; Kim, EY; Oh, HK; Park, KC; Ryu, JI, 2012) |
| "The relative increased risk of breast cancer in MS women under IS treatment warrants further attention." | 1.35 | Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis. ( Berthier, F; Clavelou, P; Danzon, A; de Seze, J; Debouverie, M; Defer, G; Gout, O; Lebrun, C; Rumbach, L; Vermersch, P; Wiertlevski, S, 2008) |
| "The frequency of cancer-associated mortality was 11% that was 2% of the total lupus population." | 1.33 | [The occurrence of malignancies in a Hungarian lupus population]. ( Kiss, E; Szegedi, G; Szekanecz, E; Tarr, T; Zeher, M, 2006) |
| "In mice, retrovirus-associated breast cancers are promoted by immune mechanisms, and immunosuppression during the premalignant phase reduces the incidence of breast cancer and prolongs life." | 1.29 | Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation. ( Grayson, H; Henderson, R; Opelz, G; Stewart, T; Tsai, SC, 1995) |
| "The visceral carcinomas (2 breast cancers, 1 carcinoma respectively of the pancreas, the rectum, the liver, the kidneys, the renal pelvis, and the urinary bladder, and one seminoma) were treated by generally accepted surgical principles as far as treatment of the patients was possible." | 1.26 | [Malignant tumors in bearers of kidney grafts in immunosuppressive therapy]. ( Binswanger, U; Briner, J; Largiadèr, F; Uhlschmid, G; Vollenweider, A, 1982) |
| "Azathioprine was administered to 25 patients with severe, progressive polyarthritis in a mean dose of 1." | 1.26 | Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients. ( Pinals, RS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Milosevic, Z | 1 |
| Tanic, N | 1 |
| Bankovic, J | 1 |
| Stankovic, T | 1 |
| Buta, M | 1 |
| Lavrnic, D | 1 |
| Milovanovic, Z | 1 |
| Pupic, G | 1 |
| Stojkovic, S | 1 |
| Milinkovic, V | 1 |
| Ito, Y | 1 |
| Dzodic, R | 1 |
| Satish, R | 1 |
| Rout, P | 1 |
| Alexander, B | 1 |
| Mamtani, R | 1 |
| Clark, AS | 1 |
| Scott, FI | 1 |
| Brensinger, CM | 1 |
| Boursi, B | 1 |
| Chen, L | 1 |
| Xie, F | 1 |
| Yun, H | 1 |
| Osterman, MT | 1 |
| Curtis, JR | 1 |
| Lewis, JD | 1 |
| Vingerhoedt, NM | 1 |
| Janssen, S | 1 |
| Mravunac, M | 1 |
| Wauters, CA | 1 |
| Strobbe, LJ | 1 |
| Park, KC | 1 |
| Ju, DU | 1 |
| Heo, SW | 1 |
| Ryu, JI | 1 |
| Cho, JY | 1 |
| Kim, EJ | 1 |
| Oh, HK | 1 |
| Kim, EY | 1 |
| Balal, M | 1 |
| Seyrek, N | 1 |
| Karayaylali, I | 1 |
| Paydas, S | 1 |
| Kitayama, T | 1 |
| Marubayashi, S | 1 |
| Hayamizu, K | 1 |
| Tashiro, H | 1 |
| Ohdan, H | 1 |
| Ikeda, S | 1 |
| Okimoto, T | 1 |
| Okajima, M | 1 |
| Kataoka, T | 1 |
| Sugino, K | 1 |
| Asahara, T | 1 |
| Fukuda, Y | 1 |
| Dohi, K | 1 |
| Tarr, T | 1 |
| Szekanecz, E | 1 |
| Zeher, M | 1 |
| Szegedi, G | 1 |
| Kiss, E | 1 |
| Lebrun, C | 1 |
| Debouverie, M | 1 |
| Vermersch, P | 1 |
| Clavelou, P | 1 |
| Rumbach, L | 1 |
| de Seze, J | 1 |
| Wiertlevski, S | 1 |
| Defer, G | 1 |
| Gout, O | 1 |
| Berthier, F | 1 |
| Danzon, A | 1 |
| Vollenweider, A | 1 |
| Largiadèr, F | 1 |
| Uhlschmid, G | 1 |
| Binswanger, U | 1 |
| Briner, J | 1 |
| Schlag, P | 1 |
| Veser, J | 1 |
| Geier, G | 1 |
| Breitig, D | 1 |
| Herfarth, C | 1 |
| Stewart, T | 1 |
| Tsai, SC | 1 |
| Grayson, H | 1 |
| Henderson, R | 1 |
| Opelz, G | 1 |
| Amato, MP | 1 |
| Pracucci, G | 1 |
| Ponziani, G | 1 |
| Siracusa, G | 1 |
| Fratiglioni, L | 1 |
| Amaducci, L | 1 |
| Schaller, M | 1 |
| Korting, HC | 1 |
| Meurer, M | 1 |
| Schirren, CG | 1 |
| Campbell, A | 1 |
| Moazami, N | 1 |
| Ditkoff, BA | 1 |
| Kurtz, E | 1 |
| Estabrook, A | 1 |
| Schnabel, F | 1 |
| Hall, RL | 1 |
| Leahy, MF | 1 |
| Krutchik, AN | 1 |
| Buzdar, AU | 1 |
| Tashima, CK | 1 |
| Pinals, RS | 1 |
| Gleason, TH | 1 |
| Hamlin, WB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma[NCT00307606] | Phase 4 | 40 participants (Anticipated) | Interventional | 2005-12-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Breast Cancer
| Article | Year |
|---|---|
Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case.
Topics: Azathioprine; Breast Neoplasms; Carcinoma, Ductal, Breast; Colonic Neoplasms; Colonic Polyps; Drug T | 2004 |
19 other studies available for azathioprine and Breast Cancer
| Article | Year |
|---|---|
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Genetic alterations in quadruple malignancies of a patient with multiple sclerosis: their role in malignancy development and response to therapy.
Topics: Adult; Azathioprine; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Medulla | 2014 |
Double primary carcinoma in a renal allograft recipient.
Topics: Allografts; Azathioprine; Biopsy; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Papillary; | 2014 |
Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study.
Topics: Adalimumab; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Cohort S | 2016 |
[Granulomatous lobular mastitis: a benign abnormality that mimics malignancy].
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Cytodiagnosis; Diagnosis, Different | 2008 |
[A case of squamous cell carcinoma of the breast in a patient with Crohn's disease taking azathioprine].
Topics: Adult; Azathioprine; Breast Neoplasms; Carcinoma, Squamous Cell; Colonoscopy; Combined Modality Ther | 2012 |
Report of a renal transplanted patient with fibroadenoma occurring in a short time.
Topics: Adult; Azathioprine; Breast Neoplasms; Creatinine; Cyclosporine; Female; Fibroadenoma; Humans; Immun | 2003 |
[The occurrence of malignancies in a Hungarian lupus population].
Topics: Adult; Aged; Azathioprine; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Female; Gastroin | 2006 |
Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis.
Topics: Adult; Azathioprine; Breast Neoplasms; Central Nervous System Neoplasms; Cyclophosphamide; Digestive | 2008 |
[Malignant tumors in bearers of kidney grafts in immunosuppressive therapy].
Topics: Adult; Antilymphocyte Serum; Azathioprine; Breast Neoplasms; Dysgerminoma; Female; Humans; Immunosup | 1982 |
[Cytostatic effects on nucleic acid synthesis in primary tumors and lymph node metastases of human breast cancer (author's transl)].
Topics: Azathioprine; Breast Neoplasms; Cyclophosphamide; Female; Humans; Lymphatic Metastasis; Nucleic Acid | 1980 |
Incidence of de-novo breast cancer in women chronically immunosuppressed after organ transplantation.
Topics: Adult; Azathioprine; Breast Neoplasms; Cohort Studies; Cyclosporine; Europe; Female; Follow-Up Studi | 1995 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
[Generalized Mycobacterium avium-intracellulare infection due to immunosuppressive therapy of paraneoplastic dermatomyositis].
Topics: Adenocarcinoma; Azathioprine; Biopsy; Breast Neoplasms; Dermatomyositis; Female; Fluocortolone; Huma | 1997 |
Short-term outcome of chronic immunosuppression on the development of breast lesions in premenopausal heart and lung transplant patients.
Topics: Adolescent; Adult; Azathioprine; Biopsy, Needle; Breast Neoplasms; Child; Chronic Disease; Cyclospor | 1998 |
Acquired Factor VIII autoantibody: four cases demonstrating the heterogenous nature of this condition and problems involved in diagnosis and treatment.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Azathiop | 2001 |
Azathioprine and breast carcinoma.
Topics: Adult; Azathioprine; Breast Neoplasms; Female; Humans; Immunosuppression Therapy; Middle Aged | 1978 |
Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients.
Topics: Adenocarcinoma; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Carcinoma; Femal | 1976 |
Disseminated toxoplasmosis in the compromised host. A report of five cases.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Autopsy; Azathioprine; Brain; Breast Neoplasms; Female; | 1974 |