azathioprine has been researched along with Brain Neoplasms in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To our knowledge this is the first reported case of LYG related to azathioprine therapy in Crohn disease." | 7.80 | Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. ( Belletrutti, PJ; Connors, W; Griffiths, C; Patel, J, 2014) |
| " To our knowledge this is the first reported case of LYG related to azathioprine therapy in Crohn disease." | 3.80 | Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. ( Belletrutti, PJ; Connors, W; Griffiths, C; Patel, J, 2014) |
| "A woman, aged 58, who had undergone prolonged treatment with corticosteroids for generalized necrotizing vasculitis, and had received azathioprine (Imurel) for 18 months, 4 years after discontinuing the latter treatment, developed peripheral neuropathy and a rapidly progressing cerebral disorder suggesting a basal meningeal process." | 3.66 | Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression. ( Jellinger, K; Kothbauer, P; Sunder-Plassmann, E; Weiss, R, 1979) |
| "Multiple brain tumors were found and diagnosed as having B-cell, diffuse large cell type malignant lymphoma." | 1.30 | [A case of malignant lymphoma after renal transplantation]. ( Ikeda, K; Inoue, S; Matsuura, O; Murakami, S; Oyama, H; Sugiyama, T; Yamao, K, 1997) |
| "Three years later she was found to have reticulum cell sarcoma (RCS) of the left frontoparietal area; it responded well to radiotherapy." | 1.26 | Reticulum cell sarcoma of the uvea. ( Green, WR; Raju, VK, 1982) |
| "Necropsy revealed a reticulum cell sarcoma-microglioma of the brain." | 1.25 | Cerebral reticulum cell sarcoma after multiple renal transplants. ( Barnett, LB; Schwartz, E, 1974) |
| "Two patients developed reticulum cell sarcomata after they had been treated with azathioprine and prednisone in the course of cadaveric renal transplantation." | 1.25 | Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy. ( Doak, PB; Montgomerie, JZ; North, JD; Smith, F, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (70.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connors, W | 1 |
| Griffiths, C | 1 |
| Patel, J | 1 |
| Belletrutti, PJ | 1 |
| Glesner, MK | 1 |
| Ocias, LF | 1 |
| Larsen, TS | 1 |
| Pedersen, C | 1 |
| Loganathan, S | 1 |
| Zaitoun, A | 1 |
| Charlton, CP | 1 |
| Finelli, PF | 1 |
| Kästner, F | 1 |
| Paulus, W | 1 |
| Deckert, M | 1 |
| Schlegel, P | 1 |
| Evers, S | 1 |
| Husstedt, IW | 1 |
| Sato, A | 1 |
| Kobayashi, K | 1 |
| Okabe, H | 1 |
| Fukuda, S | 1 |
| Raju, VK | 1 |
| Green, WR | 1 |
| Oyama, H | 1 |
| Yamao, K | 1 |
| Sugiyama, T | 1 |
| Matsuura, O | 1 |
| Murakami, S | 1 |
| Ikeda, K | 1 |
| Inoue, S | 1 |
| Jellinger, K | 1 |
| Kothbauer, P | 1 |
| Weiss, R | 1 |
| Sunder-Plassmann, E | 1 |
| Schneck, SA | 1 |
| Penn, I | 2 |
| Birkeland, SA | 1 |
| Kemp, E | 1 |
| Ulrich, J | 1 |
| Wüthrich, R | 1 |
| Myers, BD | 1 |
| Kessler, E | 1 |
| Levi, J | 1 |
| Pick, A | 1 |
| Rosenfeld, JB | 1 |
| Tikvah, P | 1 |
| Cho, ES | 1 |
| Connolly, E | 1 |
| Porro, RS | 1 |
| Barnett, LB | 1 |
| Schwartz, E | 1 |
| Guisan, Y | 1 |
| Enderlin, F | 1 |
| Harder, F | 1 |
| Brunner, F | 1 |
| Thiel, G | 1 |
| Bernhardt, JP | 1 |
| Schädeli, J | 1 |
| Mihatsch, M | 1 |
| Moser, KD | 1 |
| Araoz, CA | 1 |
| Smith, PL | 1 |
| Doak, PB | 1 |
| Montgomerie, JZ | 1 |
| North, JD | 1 |
| Smith, F | 1 |
| Hammond, W | 1 |
| Brettschneider, L | 1 |
| Starzl, TE | 1 |
1 review available for azathioprine and Brain Neoplasms
| Article | Year |
|---|---|
[Primary CNS lymphoma in azathioprine therapy for autoimmune diseases: review of the literature and case report].
Topics: Adult; Autoimmune Diseases; Azathioprine; Brain Neoplasms; Colitis, Ulcerative; Female; Humans; Immu | 2007 |
19 other studies available for azathioprine and Brain Neoplasms
| Article | Year |
|---|---|
Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease.
Topics: Adult; Azathioprine; Brain Neoplasms; Crohn Disease; Female; Humans; Immunocompromised Host; Immunos | 2014 |
Primary CNS lymphoma in a patient treated with azathioprine.
Topics: Adult; Azathioprine; Biopsy; Brain; Brain Neoplasms; Diagnosis, Differential; Humans; Immunosuppress | 2014 |
Lymphoma with central nervous system involvement in a young patient with Crohn disease treated with azathioprine.
Topics: Adolescent; Azathioprine; Brain Neoplasms; Crohn Disease; Female; Humans; Immunosuppressive Agents; | 2010 |
Primary CNS lymphoma in myasthenic on long-term azathioprine.
Topics: Antigens, CD20; Antimetabolites, Antineoplastic; Azathioprine; Brain Neoplasms; Diagnosis, Different | 2005 |
A case of the hypereosinophilic syndrome complicated by malignant lymphoma.
Topics: Adolescent; Adult; Azathioprine; Brain Neoplasms; Eosinophilia; Female; Humans; Lymphoma; Prednisolo | 1983 |
Reticulum cell sarcoma of the uvea.
Topics: Azathioprine; Brain Neoplasms; Eye; Female; Frontal Lobe; Humans; Lymphoma, Non-Hodgkin; Middle Aged | 1982 |
[A case of malignant lymphoma after renal transplantation].
Topics: Adult; Azathioprine; Brain Neoplasms; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Immuno | 1997 |
Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression.
Topics: Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Middle Aged; Necr | 1979 |
De-novo brain tumours in renal-transplant recipients.
Topics: Adolescent; Adult; Azathioprine; Brain; Brain Neoplasms; Cadaver; Follow-Up Studies; Humans; Immunos | 1971 |
Immunosuppression and intracerebral lymphomas.
Topics: Adolescent; Adult; Age Factors; Azathioprine; Brain Neoplasms; Humans; Immune Tolerance; Immunosuppr | 1971 |
Malignant tumours following immunosuppression in renal transplantation.
Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom | 1973 |
Multiple sclerosis: reticulum cell sarcoma of the nervous system in a patient treated with immunosuppressive drugs.
Topics: Adrenocorticotropic Hormone; Adult; Autopsy; Azathioprine; Biopsy, Needle; Brain Neoplasms; Cortison | 1974 |
Kaposi sarcoma in kidney transplant recipients.
Topics: Adult; Antilymphocyte Serum; Autopsy; Azathioprine; Brain Neoplasms; Cadaver; Female; Graft Rejectio | 1974 |
Primary reticulum cell sarcoma of the brain in a renal transplantation recipient.
Topics: Abscess; Adult; Azathioprine; Brain Neoplasms; Chronic Disease; Epididymitis; Frontal Lobe; Glomerul | 1974 |
Cerebral reticulum cell sarcoma after multiple renal transplants.
Topics: Adult; Azathioprine; Brain Neoplasms; Dactinomycin; Glomerulonephritis; Humans; Immunosuppression Th | 1974 |
[Malignant tumors following transplantation. Case reports and review of the literature].
Topics: Adult; Antilymphocyte Serum; Azathioprine; Brain Neoplasms; Female; Graft Rejection; Humans; Kidney | 1973 |
Immunosuppressive therapy and reticulum cell sarcomas of the brain. A report of 2 cases.
Topics: Adult; Azathioprine; Brain Neoplasms; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Male | 1972 |
Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy.
Topics: Adult; Azathioprine; Brain Neoplasms; Female; Herpes Simplex; Humans; Kidney Transplantation; Liver | 1968 |
Malignant lymphomas in transplantation patients.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppre | 1969 |