azathioprine has been researched along with Bone Fractures in 4 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine was associated with an increase in overall fracture risk, but besides this, none of the drugs was significantly associated with overall fracture risk or risk of hip, spine, or forearm fracture." | 1.33 | Methotrexate, azathioprine, cyclosporine, and risk of fracture. ( Mosekilde, L; Rejnmark, L; Vestergaard, P, 2006) |
| "Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors." | 1.31 | Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prasad, R | 1 |
| De Silva, M | 1 |
| Sprague, SM | 1 |
| Josephson, MA | 1 |
| Vestergaard, P | 1 |
| Rejnmark, L | 1 |
| Mosekilde, L | 1 |
| Patel, S | 1 |
| Kwan, JT | 1 |
| McCloskey, E | 1 |
| McGee, G | 1 |
| Thomas, G | 1 |
| Johnson, D | 1 |
| Wills, R | 1 |
| Ogunremi, L | 1 |
| Barron, J | 1 |
1 review available for azathioprine and Bone Fractures
| Article | Year |
|---|---|
Bone disease after kidney transplantation.
Topics: Azathioprine; Bone Density; Bone Diseases; Calcifediol; Cyclosporine; Fractures, Bone; Graft Rejecti | 2004 |
3 other studies available for azathioprine and Bone Fractures
| Article | Year |
|---|---|
Osteoporosis with underlying connective tissue disease: an unusual case.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant | 2002 |
Methotrexate, azathioprine, cyclosporine, and risk of fracture.
Topics: Adult; Aged; Azathioprine; Case-Control Studies; Cyclosporine; Enzyme Inhibitors; Female; Fractures, | 2006 |
Prevalence and causes of low bone density and fractures in kidney transplant patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Back Pain; Biomarkers; Bone Density; Cyclo | 2001 |