Page last updated: 2024-10-23

azathioprine and Body Weight

azathioprine has been researched along with Body Weight in 71 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"In order to evaluate whether immunosuppressive agents such as mycophenolate mofetil (MMF) and azathioprine would differently influence the outcome of the renal transplants, we prospectively analyzed the incidence of acute rejection episodes, cytomegalovirus infection within the first 6 months following renal transplantation and 5 yr graft survival rate after minimizing influences of donor factors by grafting the same cadaveric donor kidney."7.73The influence of mycophenolate mofetil and azathioprine on the same cadaveric donor renal transplantation. ( Joh, JW; Kim, SJ; Lee, DS; Lee, HH; Lee, KW; Lee, SK, 2005)
" It was evaluated, in comparison with azathioprine (AZA) and methylprednisolone acetate (MPA), for its therapeutic effects on the glomerulonephritis induced in rats by rabbit antiserum against the rat glomerular basement membrane."7.68Therapeutic effects of leflunomide, a new antirheumatic drug, on glomerulonephritis induced by the antibasement membrane antibody in rats. ( Gotoh, K; Hayashi, S; Inazu, M; Inoue, T; Ogawa, T, 1991)
"The present study was made to investigate the antinephritic effect of mizoribine in comparison to that of azathioprine by using the nephrotic type of anti-rat glomerular basement membrane rabbit serum (anti-GBM serum)-induced nephritis in rats."7.66Studies on antinephritic effect of mizoribine (p-INN, Bredinin), a new immunosuppressive agent, and azathioprine (1) effect on the nephrotic type of anti-GBM nephritis in rats. ( Ito, M; Okamoto, K; Suzuki, Y, 1983)
"The incidence of posttransplant diabetes mellitus (PTDM) was compared in three groups of renal transplant recipients: nondiabetic patients who had been randomized between 1980 and 1983 to receive antilymphoblast globulin (ALG), azathioprine (AZA), and prednisone (P) (group 1) or cyclosporine (CsA) plus prednisone (group 2)."5.06The impact of cyclosporine and combination immunosuppression on the incidence of posttransplant diabetes in renal allograft recipients. ( Ascher, N; Boudreaux, JP; Canafax, DM; Fryd, DS; McHugh, L; Najarian, JS; Payne, W; Simmons, RL; Sutherland, DE, 1987)
"In order to evaluate whether immunosuppressive agents such as mycophenolate mofetil (MMF) and azathioprine would differently influence the outcome of the renal transplants, we prospectively analyzed the incidence of acute rejection episodes, cytomegalovirus infection within the first 6 months following renal transplantation and 5 yr graft survival rate after minimizing influences of donor factors by grafting the same cadaveric donor kidney."3.73The influence of mycophenolate mofetil and azathioprine on the same cadaveric donor renal transplantation. ( Joh, JW; Kim, SJ; Lee, DS; Lee, HH; Lee, KW; Lee, SK, 2005)
" It was evaluated, in comparison with azathioprine (AZA) and methylprednisolone acetate (MPA), for its therapeutic effects on the glomerulonephritis induced in rats by rabbit antiserum against the rat glomerular basement membrane."3.68Therapeutic effects of leflunomide, a new antirheumatic drug, on glomerulonephritis induced by the antibasement membrane antibody in rats. ( Gotoh, K; Hayashi, S; Inazu, M; Inoue, T; Ogawa, T, 1991)
" Azathioprine in different doses, and cyclophosamide and methylprednisolone combinations did not result in predictable leukocytopenia without significant mortality."3.67Development of a leukocytopenic baby guinea pig model with azathioprine and cyclophosphamide. ( Cleveland, RP; Kumar, A; Leonard, MC, 1989)
"The present study was made to investigate the antinephritic effect of mizoribine in comparison to that of azathioprine by using the nephrotic type of anti-rat glomerular basement membrane rabbit serum (anti-GBM serum)-induced nephritis in rats."3.66Studies on antinephritic effect of mizoribine (p-INN, Bredinin), a new immunosuppressive agent, and azathioprine (1) effect on the nephrotic type of anti-GBM nephritis in rats. ( Ito, M; Okamoto, K; Suzuki, Y, 1983)
"To investigate whether AZA therapy is optimised by individualised dosing based on thiopurine methyltransferase (TPMT) activity and 6TGN concentrations."2.79Randomised clinical trial: individualised vs. weight-based dosing of azathioprine in Crohn's disease. ( Bentsen, JL; Dassopoulos, T; Dubinsky, MC; Galanko, JA; Hanauer, SB; Martin, CF; Sandler, RS; Seidman, EG, 2014)
"Refractory sprue is a rare and severe malabsorptive disorder that mimics celiac disease but is refractory to a gluten-free diet and is without initial evidence of overt lymphoma."2.70Azathioprine in refractory sprue: results from a prospective, open-label study. ( Bai, JC; Cabanne, A; Capucchio, M; Cherñavsky, A; Fiorini, A; Kogan, Z; Mauriño, E; Mazure, R; Niveloni, S; Pedreira, S; Reyes, H; Smecuol, E; Vazquez, H, 2002)
" Additionally, the review addresses the benefits and risks of routine measurement of thiopurine methyltransferase enzyme activity or genotype before starting thiopurine therapy compared with empiric weight-based dosing and explores the performance of different trough drug concentrations for anti-tumor necrosis factor agents and thiopurines to inform clinical decision making when applying TDM in a reactive setting."2.55American Gastroenterological Association Institute Technical Review on the Role of Therapeutic Drug Monitoring in the Management of Inflammatory Bowel Diseases. ( Falck-Ytter, Y; Herfarth, H; Katz, J; Singh, S; Vande Casteele, N, 2017)
"Azathioprine (AZA) is a cytotoxic immunosuppressive drug used in the prevention of rejection in organ transplants and the treatment of auto-immune diseases."1.35The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse. ( Chen, CM; Gibson, FM; Marway, HK; McKeag, S; Mifsud, CV; Molyneux, G; Pilling, AM; Turton, JA; Whayman, MJ, 2008)
"Univariate analysis identified the duration of transplant, papilla bleeding index, creatinine serum concentration, azathioprine and prednisolone dosage as risk factors for overgrowth severity."1.33Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers. ( Ellis, JS; Seymour, RA; Thomason, JM, 2005)
" In this study, we examined the dosing time-dependent alterations in the pharmacokinetics and pharmacodynamics of Miz."1.31Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft. ( Fujimura, A; Higuchi, S; Hishikawa, S; Kobayashi, E; Sudoh, T; Sugimoto, K; Sunaga, K; To, H; Uchida, H; Xiu, DR, 2001)
" Duration of treatment, dosage of drugs per kg body weight and serum cyclosporin levels were recorded."1.30Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy. ( Ashley, FP; Koffman, CG; Morel, A; Ogg, CS; Rigden, SP; Smith, D; Wilson, RF, 1998)
" Differential analysis of white blood cells indicated a decline in lymphocyte number, in particular, with increased dosage of azathioprine."1.30Tilapia (Oreochromis niloticus) dosed with azathioprine display immune effects similar to those seen in mammals, including apoptosis. ( Gogal, RM; Holladay, SD; Robertson, JL; Smith, BJ; Smith, SA, 1999)
"Azathioprine treatment alone did not alter ionized calcium, 1,25(OH)2VitD, or PTH levels."1.29Azathioprine alone is bone sparing and does not alter cyclosporin A-induced osteopenia in the rat. ( Armstrong, EC; Bryer, HP; Buchinsky, FJ; Epstein, S; Isserow, JA; Mann, GN; Romero, DF; Rucinski, B, 1995)
"The diagnostic possibility of Crohn's disease in unusual sites should be considered in any child with unexplained failure to thrive."1.26Isolated gastroduodenal Crohn's disease in a ten-year-old girl. ( Malleson, P, 1980)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199047 (66.20)18.7374
1990's11 (15.49)18.2507
2000's11 (15.49)29.6817
2010's2 (2.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vande Casteele, N1
Herfarth, H1
Katz, J1
Falck-Ytter, Y1
Singh, S1
Dassopoulos, T1
Dubinsky, MC1
Bentsen, JL1
Martin, CF1
Galanko, JA1
Seidman, EG1
Sandler, RS1
Hanauer, SB1
Takae, Y1
Nishikawa, T1
Amagai, M1
Diamanti, A1
Basso, MS1
Gambarara, M1
Papadatou, B1
Bracci, F1
Noto, C1
Castro, M1
Ojogho, ON1
Sahney, S1
Cutler, D1
Baron, PW1
Abdelhalim, FM1
Hasan, SM1
Concepcion, W1
Mauriño, E1
Niveloni, S1
Cherñavsky, A1
Pedreira, S1
Mazure, R1
Vazquez, H1
Reyes, H1
Fiorini, A1
Smecuol, E1
Cabanne, A1
Capucchio, M1
Kogan, Z1
Bai, JC1
To, H1
Xiu, DR1
Hishikawa, S1
Uchida, H2
Sudoh, T1
Sunaga, K1
Sugimoto, K1
Higuchi, S1
Fujimura, A1
Kobayashi, E1
COSIMI, AB1
RECKLER, JM1
WADDELL, WR1
Borrelli, O1
Bascietto, C1
Viola, F1
Bueno de Mesquita, M1
Barbato, M1
Mancini, V1
Bosco, S1
Cucchiara, S1
Grebe, SO1
Mueller, TF1
Troeltsch, M1
Ebel, H1
Lange, H1
Joh, JW1
Lee, HH1
Lee, DS1
Lee, KW1
Lee, SK1
Kim, SJ1
Thomason, JM1
Seymour, RA1
Ellis, JS1
Molyneux, G1
Gibson, FM1
Chen, CM1
Marway, HK1
McKeag, S1
Mifsud, CV1
Pilling, AM1
Whayman, MJ1
Turton, JA1
Dardenne, M1
Savino, W1
Wade, S1
Kaiserlian, D1
Lemonnier, D1
Bach, JF1
Okamoto, K1
Ito, M1
Suzuki, Y1
Malleson, P1
De Waal, EJ1
Timmerman, HH1
Dortant, PM1
Kranjc, MA1
Van Loveren, H1
Bryer, HP1
Isserow, JA1
Armstrong, EC1
Mann, GN1
Rucinski, B1
Buchinsky, FJ1
Romero, DF1
Epstein, S1
Hilbrands, LB1
Hoitsma, AJ1
Koene, RA1
Heaf, JG1
Ladefoged, J1
Wilson, RF1
Morel, A1
Smith, D1
Koffman, CG1
Ogg, CS1
Rigden, SP1
Ashley, FP1
Lulin, M1
Yantang, L1
Gogal, RM1
Smith, BJ1
Robertson, JL1
Smith, SA1
Holladay, SD1
Molinaro, M1
Regazzi, MB1
Pasquino, S1
Rinaldi, M1
Iacona, I1
Campana, C1
Viganò, M1
Beaumont, JE1
Galla, JH1
Luke, RG1
Rees, ED1
Siegel, RR1
McMillen, MA1
Cerra, FB1
Baliah, T1
Anthone, S1
Anthone, R1
Menahan, LA1
Kemp, RG1
Scott, JR2
Ogawa, T1
Inazu, M1
Gotoh, K1
Inoue, T1
Hayashi, S1
Pirsch, JD1
Armbrust, MJ1
Knechtle, SJ1
Reed, A1
D'Alessandro, AM1
Sollinger, HW1
Belzer, FO1
Dammenhayn, L1
Haverich, A1
Demertzis, S1
Reimer, P1
Kemnitz, J1
Klebe, JG1
Marushak, A1
Bock, J1
Ito, A1
Mori, M1
Naito, M1
Kumar, A1
Leonard, MC1
Cleveland, RP1
Kupin, W2
Venkat, KK2
Oh, HK2
Hodson, EM1
Knight, JF1
Sheil, AG1
Roy, LP1
Dienst, S1
Boudreaux, JP1
McHugh, L1
Canafax, DM1
Ascher, N1
Sutherland, DE1
Payne, W1
Simmons, RL1
Najarian, JS2
Fryd, DS1
Smith, KP1
Zardiackas, LD1
Didlake, RH1
Gotjamanos, T1
Babington, RG1
Wedeking, PW1
Vetten, KB1
Mallinson, CN1
Candy, JC1
Cowan, R1
Prior, A1
Atkinson, JP1
Frank, MM1
Casey, TP1
Mathews, JD1
Buckley, JD1
Gledhill, VX1
Jursik, JJ1
De Quesada, AM1
Shires, DL1
Bradley, KP1
Papp, JP1
Watson, DW1
Bull, FE1
Kierfeld, G1
Mellin, P1
Schwalm, E1
Schreiber, M1
Schreiber, B1
Jakóbisiak, M1
Kamiński, M1
Kossakowska, AE1
Rymaszewska-Kossakowska, T1
Toledo-Pereyra, LH1
Idezuki, Y1
Goetz, FC1
Lillehei, RC2
Gault, MH1
Ackman, D1
Morehouse, D1
Dossetor, JB1
Koumans, RK1
Burke, JF1
Turcotte, JG1
Herrmann, TJ1
Haig, O1
O'Dell, C1
Cerny, J1
Greene, JA1
Rao, MM1
Meadows, R1
Rao, MD1
Knight, PR1
Cachera, JP1
Poulain, H1
Crepin, Y1
Fernandez, O1
Hollman, KH1
Halpern, B1
Kalter, SS1
Ratner, IA1
Britton, HA1
Vice, TE1
Eugster, AK1
Rodriguez, AR1
Freudenberg, J1
Ruiz, JO1
Schultz, LS1
Van Vroonhoven, TJ1
Malamud, DM1
Malt, RA1
Sokolowski, J2
Olszewski, W2
Orlowski, T1
Nielubowicz, J1
Gradowska, L1
Rowiński, W1
Klopotowska, E1
Rosenthale, ME1
Datko, LJ1
Kassarich, J1
Schneider, F1
Drucker, WR1
Jeejeebhoy, KN1
Frankel, HH1
Yamamoto, RS1
Weisburger, EK1
Weisburger, JH1
Schmidt, JG1
Lischka, G1
Worthington, M1
Baron, S1
Makulu, DR1
Wright, P1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Relationship Between Baseline Burden of Disease and Anti-TNF Drug Trough Levels in Ulcerative Colitis.[NCT03808506]0 participants (Actual)Observational2019-09-01Withdrawn (stopped due to no recruitment during COVID pandemic)
A Multi-site Trial of Azathioprine Dosing in Crohn's Disease[NCT00113503]Phase 250 participants (Actual)Interventional2005-07-31Terminated (stopped due to Insufficient enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Body Weight

ArticleYear
American Gastroenterological Association Institute Technical Review on the Role of Therapeutic Drug Monitoring in the Management of Inflammatory Bowel Diseases.
    Gastroenterology, 2017, Volume: 153, Issue:3

    Topics: Antibodies, Monoclonal; Azathioprine; Body Weight; Drug Monitoring; Humans; Immunosuppressive Agents

2017

Trials

8 trials available for azathioprine and Body Weight

ArticleYear
Randomised clinical trial: individualised vs. weight-based dosing of azathioprine in Crohn's disease.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Body Weight; Child; Crohn Disease; Double-Blind Method; Female; Hum

2014
Azathioprine in refractory sprue: results from a prospective, open-label study.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:10

    Topics: Adult; Aged; alpha 1-Antitrypsin; Autoantibodies; Azathioprine; Biopsy, Needle; Body Weight; Celiac

2002
Infliximab heals intestinal inflammatory lesions and restores growth in children with Crohn's disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:5

    Topics: Adolescent; Antibodies, Monoclonal; Azathioprine; Blood Sedimentation; Body Height; Body Weight; C-R

2004
The effect of immunosuppressive drugs on quality of life after renal transplantation.
    Transplantation, 1995, May-15, Volume: 59, Issue:9

    Topics: Adult; Azathioprine; Body Weight; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection;

1995
Human placental lactogenic hormone as a parameter for placental function in renal transplanted women.
    Acta obstetricia et gynecologica Scandinavica, 1990, Volume: 69, Issue:1

    Topics: Azathioprine; Body Weight; Creatinine; Cyclosporins; Female; Fetus; Humans; Kidney Transplantation;

1990
Cyclosporin A as sole immunosuppressive agent for renal transplantation in children: effect on catch-up growth.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Body Weight; Child; Clinical Trials as Topic; Cyclos

1989
The impact of cyclosporine and combination immunosuppression on the incidence of posttransplant diabetes in renal allograft recipients.
    Transplantation, 1987, Volume: 44, Issue:3

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Body Weight; Cyclosporins; Diabetes Mellitus; Drug Therap

1987
Azathioprine treatment in Crohn's disease.
    The American journal of gastroenterology, 1974, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Body Weight; Clinical Trials as Topic; Crohn Disease; Diarrhea; Fem

1974

Other Studies

62 other studies available for azathioprine and Body Weight

ArticleYear
Pemphigus mouse model as a tool to evaluate various immunosuppressive therapies.
    Experimental dermatology, 2009, Volume: 18, Issue:3

    Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide; Cyclosporine; Desmoglein 3; Dexamethasone; Dis

2009
Positive impact of blocking tumor necrosis factor alpha on the nutritional status in pediatric Crohn's disease patients.
    International journal of colorectal disease, 2009, Volume: 24, Issue:1

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Body Heig

2009
Mycophenolate mofetil without antibody induction in pediatric renal transplantation.
    Transplantation proceedings, 2002, Volume: 34, Issue:5

    Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Body Weight; Cadaver; California; Child; Cyclosporin

2002
Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft.
    Research communications in molecular pathology and pharmacology, 2001, Volume: 110, Issue:5-6

    Topics: Animals; Area Under Curve; Azathioprine; Body Weight; Dose-Response Relationship, Drug; Drug Adminis

2001
METABOLIC STUDIES ON RENAL HOMOGRAFT PATIENTS.
    The Journal of surgical research, 1965, Volume: 5

    Topics: Allografts; Antimetabolites; Azathioprine; Blood Urea Nitrogen; Body Weight; Dactinomycin; Drug Ther

1965
Effect of mycophenolate mofetil on kidney graft function and body weight in patients with chronic allograft nephropathy.
    Transplantation proceedings, 2004, Volume: 36, Issue:10

    Topics: Albuminuria; Azathioprine; Body Weight; Creatinine; Cyclosporine; Drug Therapy, Combination; Graft S

2004
The influence of mycophenolate mofetil and azathioprine on the same cadaveric donor renal transplantation.
    Journal of Korean medical science, 2005, Volume: 20, Issue:1

    Topics: ABO Blood-Group System; Adult; Azathioprine; Body Weight; Cadaver; Cytomegalovirus; Cytomegalovirus

2005
Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers.
    Journal of clinical periodontology, 2005, Volume: 32, Issue:3

    Topics: Anti-Inflammatory Agents; Azathioprine; Body Weight; Creatinine; Cyclosporine; Dental Plaque Index;

2005
The haemotoxicity of azathioprine in repeat dose studies in the female CD-1 mouse.
    International journal of experimental pathology, 2008, Volume: 89, Issue:2

    Topics: Animals; Apoptosis; Azathioprine; Body Weight; Bone Marrow Cells; Colony-Forming Units Assay; Diseas

2008
In vivo and in vitro studies of thymulin in marginally zinc-deficient mice.
    European journal of immunology, 1984, Volume: 14, Issue:5

    Topics: Animals; Azathioprine; Body Weight; Female; Mice; Mice, Inbred C57BL; Organ Size; T-Lymphocytes; Thy

1984
Studies on antinephritic effect of mizoribine (p-INN, Bredinin), a new immunosuppressive agent, and azathioprine (1) effect on the nephrotic type of anti-GBM nephritis in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:3

    Topics: Animals; Azathioprine; Basement Membrane; Body Weight; Immune Sera; Immunosuppressive Agents; Kidney

1983
Isolated gastroduodenal Crohn's disease in a ten-year-old girl.
    Postgraduate medical journal, 1980, Volume: 56, Issue:654

    Topics: Azathioprine; Body Weight; Child; Crohn Disease; Duodenum; Female; Humans; Steroids; Stomach

1980
Investigation of a screening battery for immunotoxicity of pharmaceuticals within a 28-day oral toxicity study using azathioprine and cyclosporin A as model compounds.
    Regulatory toxicology and pharmacology : RTP, 1995, Volume: 21, Issue:3

    Topics: Administration, Oral; Animals; Azathioprine; Blood Cell Count; Body Weight; Bone Marrow; Bone Marrow

1995
Azathioprine alone is bone sparing and does not alter cyclosporin A-induced osteopenia in the rat.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:1

    Topics: Animals; Azathioprine; Body Weight; Bone Diseases, Metabolic; Calcitriol; Calcium; Cyclosporine; Dis

1995
Hyperfiltration, creatinine clearance and chronic graft loss.
    Clinical transplantation, 1998, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Azathioprine; Body Weight; Chi-Square Distribution; Creatin

1998
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy.
    Journal of clinical periodontology, 1998, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Azathioprine; Body We

1998
Comparison of the immunosuppressive and toxic effects of TII and azathioprine.
    Transplantation proceedings, 1998, Volume: 30, Issue:7

    Topics: Animals; Atrophy; Azathioprine; Body Weight; China; Drugs, Chinese Herbal; Female; Graft Survival; H

1998
Tilapia (Oreochromis niloticus) dosed with azathioprine display immune effects similar to those seen in mammals, including apoptosis.
    Veterinary immunology and immunopathology, 1999, Volume: 68, Issue:2-4

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azathioprine; Blood Cell Count; Body Weight; Fl

1999
Pharmacokinetics of tacrolimus during the early phase after heart transplantation.
    Transplantation proceedings, 2001, Volume: 33, Issue:3

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Body Weight; Drug Therapy, Combination; Female; Heart Tra

2001
Normal serum-lipids in renal-transplant patients.
    Lancet (London, England), 1975, Mar-15, Volume: 1, Issue:7907

    Topics: Adolescent; Adult; Age Factors; Antigens; Azathioprine; Body Weight; Cholesterol; Creatine; Fasting;

1975
Swine influenza vaccination in a dialysis and transplant population.
    Journal of dialysis, 1978, Volume: 2, Issue:5-6

    Topics: Adolescent; Adult; Aged; Antibody Formation; Azathioprine; Body Weight; Child; Creatinine; Female; G

1978
The effect of several lymphocytotoxic agents on murine leukemogenesis.
    Life sciences, 1978, Oct-23, Volume: 23, Issue:16

    Topics: Aging; Animals; Azathioprine; Body Weight; Cortisone; Dacarbazine; Leukemia, Experimental; Lymphocyt

1978
The effect of immunosuppressive drugs and immunostimulating agents on reproductive performance.
    Transplantation proceedings, 1977, Volume: 9, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Azathioprine; BCG Vaccine; Body Weight; Cyclophosphamide; Female; F

1977
Fetal growth retardation associated with maternal administration of immunosuppressive drugs.
    American journal of obstetrics and gynecology, 1977, Jul-15, Volume: 128, Issue:6

    Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide; Depression, Chemical; Female; Fetal Diseases;

1977
Therapeutic effects of leflunomide, a new antirheumatic drug, on glomerulonephritis induced by the antibasement membrane antibody in rats.
    Clinical immunology and immunopathology, 1991, Volume: 61, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Anti-Idiotypic; Azathioprine; Basement

1991
Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients.
    Transplantation proceedings, 1991, Volume: 23, Issue:1 Pt 2

    Topics: Azathioprine; Body Weight; Cholesterol; Creatinine; Cyclosporins; Humans; Hypertension; Immunosuppre

1991
Growth of lung allografts after experimental transplantation.
    The Thoracic and cardiovascular surgeon, 1991, Volume: 39, Issue:1

    Topics: Animals; Azathioprine; Body Weight; Cyclosporins; Graft Rejection; Immunosuppression Therapy; Lung;

1991
Induction of uterine hemangioendothelioma and lymphoma in (C57BL/6N x C3H/2N)F1 mice by oral administration of azathioprine.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:5

    Topics: Administration, Oral; Animals; Azathioprine; Body Weight; Female; Hemangioendothelioma; Lymphoma; Ma

1989
Development of a leukocytopenic baby guinea pig model with azathioprine and cyclophosphamide.
    Comparative immunology, microbiology and infectious diseases, 1989, Volume: 12, Issue:4

    Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide; Disease Models, Animal; Guinea Pigs; Leukocyte

1989
Steroid withdrawal in cyclosporine-treated living related donor renal transplant recipients.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Azathioprine; Blood Pressure; Body Weight; Cholesterol; Creatinine; Cyclosporins; Drug Administratio

1989
Complete replacement of methylprednisolone by azathioprine in cyclosporine-treated primary cadaveric renal transplant recipients.
    Transplantation, 1988, Volume: 45, Issue:1

    Topics: Antilymphocyte Serum; Azathioprine; Blood Pressure; Body Weight; Cyclosporins; Drug Evaluation; Drug

1988
Cortisone, vitamin A, and wound healing: the importance of measuring wound surface area.
    The Journal of surgical research, 1986, Volume: 40, Issue:2

    Topics: Administration, Topical; Age Factors; Animals; Azathioprine; Body Weight; Cortisone; Female; Immunos

1986
The effect of azathioprine on phagocytic activity and morphology of reticulo-endothelial organs in mice.
    Pathology, 1971, Volume: 3, Issue:3

    Topics: Animals; Azathioprine; Body Weight; Female; Injections, Intraperitoneal; Liver; Lymph Nodes; Mice; M

1971
The influence of cinanserin and selected pharmacologic agents on experimental allergic encephalomyelitis (EAE).
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Anilides; Animals; Azathioprine; Body Weight; Chlorpheniramine; Ci

1971
Immunosuppressive therapy and anaesthesia.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-12, Volume: 47, Issue:18

    Topics: Adult; Animals; Antilymphocyte Serum; Azathioprine; Body Weight; Drug Synergism; Guanethidine; Human

1973
Two first degree relatives with dilatation of the colon due to Crohn's disease.
    Guy's Hospital reports, 1973, Volume: 122, Issue:3-4

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Azathioprine; Body Weight; Colectomy; Colitis, Ulcer

1973
Failure of cytotoxic agents to inhibit the clearance of sensitized erythrocytes.
    Journal of the Reticuloendothelial Society, 1974, Volume: 16, Issue:2

    Topics: Animals; Azathioprine; Body Weight; Cell Survival; Chromium; Cyclophosphamide; Erythrocytes; Guinea

1974
Azathioprine administration to NZB X NZW hybrid mice with lupus nephritis: beneficial effect complicated by development of malignant lymphomas.
    The New Zealand medical journal, 1973, Oct-10, Volume: 79, Issue:500

    Topics: Animals; Autoantibodies; Autoimmune Diseases; Azathioprine; Body Weight; Female; Hodgkin Disease; Ki

1973
Pattern recognition in medicine--a place for the use of principal component analysis and factor analysis.
    Australian and New Zealand journal of medicine, 1974, Volume: 4, Issue:5

    Topics: Azathioprine; Body Height; Body Weight; Child; Computers; Cyclophosphamide; Diagnosis, Differential;

1974
Hypermetabolic state following renal allotransplantation.
    Journal of the American Dietetic Association, 1972, Volume: 61, Issue:5

    Topics: Appetite; Azathioprine; Basal Metabolism; Blood Urea Nitrogen; Body Weight; Creatinine; Diet; Diet T

1972
[Effect of azathioprine and 6-methylprednisolone on growth, weight increase, blood picture and metabolism of juvenile miniature pigs].
    Zeitschrift fur experimentelle Chirurgie, 1972, Volume: 5, Issue:5

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Azathioprine; Bloo

1972
Influence of classical immunosuppressants on spleen colony formation in mice.
    Experientia, 1973, Mar-15, Volume: 29, Issue:3

    Topics: Animals; Azathioprine; Body Weight; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Clone

1973
Preservation of the small intestine for allotransplantation.
    Surgery, gynecology & obstetrics, 1973, Volume: 137, Issue:3

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Body Fluids; Body Weight; Chloramphenicol; Chlorpromazi

1973
Experimental allotransplantation of the preserved pancreas and duodenum.
    Surgery, 1969, Volume: 65, Issue:3

    Topics: Amylases; Animals; Azathioprine; Blood Glucose; Blood Proteins; Body Weight; Dogs; Duodenum; Glucose

1969
Kidney transplants: computer display of clinical and laboratory parameters. The first 100 days.
    Canadian Medical Association journal, 1969, Feb-22, Volume: 100, Issue:8

    Topics: Azathioprine; Blood Pressure; Blood Urea Nitrogen; Body Weight; Cadaver; Computers; Creatinine; Data

1969
Skin allografts and immunosuppression in the treatment of massive thermal injury.
    Surgery, 1969, Volume: 66, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Antilymphocyte Serum; Azathioprine; Body Weight; Burns; Guinea Pigs

1969
Oliguria following transplantation of kidneys donated by blood relatives.
    Surgery, gynecology & obstetrics, 1970, Volume: 130, Issue:1

    Topics: Adult; Age Factors; Anuria; Azathioprine; Blood Pressure; Body Weight; Cephalothin; Female; Histocom

1970
The effect of 9-butyl azathioprine on canine renal homograft survival.
    Transplantation, 1971, Volume: 12, Issue:4

    Topics: Animals; Azathioprine; Body Weight; Bone Marrow Diseases; Dogs; Graft Rejection; Histocompatibility;

1971
Long-term survivals after allogeneic heart grafts in dogs, physiological, morphological and bio-immunological considerations.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1970, Volume: 2, Issue:6

    Topics: Acetylcholine; Animals; Antibodies; Antilymphocyte Serum; Atropine; Azathioprine; Body Weight; Creat

1970
Wasting syndrome in thymectomized immature baboons (papio species) after infection with adenovirus type 12.
    Nature, 1967, Feb-11, Volume: 213, Issue:5076

    Topics: Adenoviridae; Alopecia; Animals; Antibody Formation; Azathioprine; Body Weight; Cobalt Isotopes; Com

1967
[Animal experimental studies on the effect of azathioprine on the formation of circulating antibodies].
    Klinische Wochenschrift, 1969, Apr-01, Volume: 47, Issue:7

    Topics: Animals; Antibodies; Antibody Formation; Antigens; Azathioprine; Body Weight; Female; Immunodiffusio

1969
Problems in absorption and immunosuppression after entire intestinal allotransplantation.
    American journal of surgery, 1972, Volume: 123, Issue:3

    Topics: Animals; Azathioprine; Body Weight; Dogs; Graft Rejection; Hematocrit; Immunosuppression Therapy; In

1972
Reversal of azathioprine-induced inhibition of hyperplasia in regenerating liver.
    Transplantation, 1972, Volume: 14, Issue:5

    Topics: Administration, Oral; Animals; Azathioprine; Body Weight; DNA; Hepatectomy; Hyperplasia; Liver; Live

1972
Biochemical and histological changes following imuran (azathioprine) administration.
    Polish medical journal, 1971, Volume: 10, Issue:3

    Topics: Animals; Azathioprine; Blood Coagulation; Blood Protein Disorders; Body Weight; Bone Marrow; Dogs; K

1971
Function of a transplanted kidney.
    Polish medical journal, 1967, Volume: 6, Issue:2

    Topics: Adult; Azathioprine; Body Weight; Female; Glomerulonephritis; Humans; Immune Tolerance; Kidney; Kidn

1967
Chemotherapy of experimental allergic encephalomyelitis (EAE).
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 179, Issue:2

    Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight;

1969
[Biochemical and histological changes resulting from the administration of an immunosuppressive agent, Imuran azathioprine].
    Polski przeglad chirurgiczny, 1970, Volume: 42, Issue:1

    Topics: Animals; Azathioprine; Body Weight; Dogs; Liver; Lymph Nodes; Lymphopenia; Serum Albumin

1970
Azathioprine: an adjunct to surgical therapy of granulomatous enteritis.
    Annals of surgery, 1970, Volume: 172, Issue:4

    Topics: Adult; Azathioprine; Blood Proteins; Body Weight; Crohn Disease; Diarrhea; Diet Therapy; Feces; Fema

1970
Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor induction by the carcinogen N-hydroxy-N-2-fluorenylacetamide.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:2

    Topics: Amides; Animals; Animals, Laboratory; Azathioprine; Body Weight; Carcinogens; Diet; Female; Liver; L

1970
[Ophthalmological symptomatology, therapy and prognosis of Fuch's and Lyell's syndromes].
    Klinische Monatsblatter fur Augenheilkunde, 1970, Volume: 157, Issue:3

    Topics: Adult; Azathioprine; Body Weight; Corneal Opacity; Cortisone; Diagnosis, Differential; Entropion; Er

1970
Effectiveness of an interferon stimulator in immunosuppressed mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:2

    Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide

1971
Immune response to insulin in guinea pigs.
    Metabolism: clinical and experimental, 1971, Volume: 20, Issue:8

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Azathioprine; Body Weight; Cattle; Chromatograp

1971