azathioprine has been researched along with Autosomal Chromosome Disorders in 11 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The correlation between these is poor, in many patients, at the dosage used in man." | 1.26 | The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens. ( Hazleman, BL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lobato, L | 1 |
| Ventura, A | 1 |
| Beirão, I | 1 |
| Miranda, HP | 1 |
| Seca, R | 1 |
| Henriques, AC | 1 |
| Teixeira, M | 1 |
| Sarmento, AM | 1 |
| Pereira, MC | 1 |
| Jensen, MK | 2 |
| Hazleman, BL | 1 |
| Paufler, S | 2 |
| Laerum, A | 1 |
| Michelmann, HW | 2 |
| Seidenkranz, HG | 2 |
| Geldermann, H | 1 |
| Perings, E | 2 |
| Smidt, D | 2 |
| Holtz, W | 1 |
| Friedrich, U | 1 |
| Zeuthen, E | 1 |
| Gevers, RH | 1 |
| Hintzen, AH | 1 |
| Kalff, MW | 1 |
| Ruys, JH | 1 |
| Dooren, LJ | 1 |
| Szántó, L | 1 |
| Czeizel, E | 1 |
| Hampel, KE | 1 |
| Lackner, A | 1 |
| Schulz, G | 1 |
| Busse, V | 1 |
| Soborg, M | 1 |
| Kotlyar, DS | 1 |
| Blonski, W | 1 |
| Diamond, RH | 1 |
| Wasik, M | 1 |
| Lichtenstein, GR | 1 |
1 review available for azathioprine and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality.
Topics: Chromosome Disorders; Humans; Inflammatory Bowel Diseases; Lymphoma, T-Cell; Mercaptopurine; Splenic | 2010 |
10 other studies available for azathioprine and Autosomal Chromosome Disorders
| Article | Year |
|---|---|
End-stage renal disease in familial amyloidosis ATTR Val30Met: a definitive indication to combined liver-kidney transplantation.
Topics: Amino Acid Substitution; Amyloid Neuropathies, Familial; Antibiotic Prophylaxis; Antilymphocyte Seru | 2003 |
Chromosome studies in patients treated with azathioprine and amethopterin.
Topics: Adult; Autoimmune Diseases; Azathioprine; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Ch | 1967 |
The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens.
Topics: Adult; Aged; Animals; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Transitional Cell; Chromosome | 1982 |
[Visual and electronic analysis of chromosomes in the Göttingen miniature pig following adminstration of azathioprine].
Topics: Animals; Azathioprine; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Female; Karyotypin | 1977 |
[The effect of azathioprine on the occurrence of chromosome abnormalities in the Göttingen miniature swine].
Topics: Animals; Azathioprine; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Female; Male; Swin | 1975 |
[Chromosome abnormalities and treatment with Imuran (azathioprine) following kidney transplantation].
Topics: Adolescent; Adult; Azathioprine; Child; Chromosome Aberrations; Chromosome Disorders; Female; Glomer | 1970 |
[Two cases of pregnancy following kidney transplantation].
Topics: Adult; Azathioprine; Chromosome Aberrations; Chromosome Disorders; Female; Graft Rejection; Humans; | 1971 |
[Chromosome aberrations related to Imuran therapy].
Topics: Azathioprine; Chromosome Aberrations; Chromosome Disorders; Humans | 1972 |
[Chromosome mutation caused by azathioprine in human leukocytes in vitro].
Topics: Azathioprine; Cells, Cultured; Chromosome Aberrations; Chromosome Disorders; Humans; In Vitro Techni | 1971 |
[A warning: chromosome anomalies after use of azathioprine (imuran)].
Topics: Azathioprine; Chromosome Aberrations; Chromosome Disorders; Humans | 1965 |