Page last updated: 2024-10-23

azathioprine and Autoimmune Thrombocytopenia

azathioprine has been researched along with Autoimmune Thrombocytopenia in 43 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"A diagnosis of autoimmune thrombocytopenia was made."6.44[Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation]. ( Fujita, H; Hashimoto, H; Kurata, M; Maeda, A; Mastusita, A; Mori, M; Nagai, K; Nagai, Y; Tabata, S; Takahashi, T; Togami, K, 2007)
"First-line AZA plus prednisone realizes a better hematological response and relapse-free duration with acceptable adverse events compared to prednisone alone in ANA-positive ITP patients."5.91Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023)
"We report on four cases (three women, one man, age at diagnosis 26-61 years) with severe autoimmune thrombocytopenia (AITP) who were refractory to initial steroid therapy (n = 4), to subsequent splenectomy (n = 2), azathioprine (n = 1), and cyclosporine (n = 1)."3.74Late spontaneous remissions in severe adult autoimmune thrombocytopenia. ( Lechner, K; Pabinger, I; Panzer, S; Simanek, R, 2007)
"Only few cases of vaccine-induced immune thrombocytopenia or immune hemolysis have been reported so far."3.01Relapse of Evans syndrome following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine: case report and literature review. ( Cvetković, M; Mitrović, M; Pantić, N; Pravdić, Z; Sabljić, N; Suvajdžić-Vuković, N; Virijević, M, 2023)
"Patients with severe immune thrombocytopenic purpura (ITP) may require an acute increase in the platelet count for surgery or ongoing hemorrhage as well as long-term maintenance treatment."2.73Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP). ( Boruchov, DM; Bussel, JB; Driscoll, MC; Gururangan, S, 2007)
"A diagnosis of autoimmune thrombocytopenia was made."2.44[Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation]. ( Fujita, H; Hashimoto, H; Kurata, M; Maeda, A; Mastusita, A; Mori, M; Nagai, K; Nagai, Y; Tabata, S; Takahashi, T; Togami, K, 2007)
"First-line AZA plus prednisone realizes a better hematological response and relapse-free duration with acceptable adverse events compared to prednisone alone in ANA-positive ITP patients."1.91Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study. ( Chen, X; Dong, Z; Ma, L; Su, J; Wang, Q; Xiao, P; Xu, M, 2023)
"Selection of patients with chronic immune thrombocytopenia from the French national prospective cohort of pediatric autoimmune cytopenia OBS'CEREVANCE and VIGICAIRE study, treated by splenectomy, hydroxychloroquine, azathioprine, or rituximab as a first second-line treatment."1.62Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation. ( Abou Chahla, W; Aladjidi, N; Armari-Alla, C; Barlogis, V; Bayart, S; Bertrand, Y; Cheikh, N; Ducassou, S; Fernandes, H; Guitton, C; Kherfellah, D; Laghouati, S; Leblanc, T; Leverger, G; Pasquet, M; Pellier, I; Savel, H; Thiébaut, R; Thomas, C; Vassal, G, 2021)
"Severe immune thrombocytopenia complicating pregnancy may require treatment beyond first-line medications (intravenous immunoglobulins or corticosteroids), but there is a paucity of literature on the use of such second-line agents in pregnancy."1.56Multidrug Therapy for Refractory Immune Thrombocytopenia in Pregnancy. ( Chan, R; Chon, AH; Kwong, K; Lee, RH; Weitz, IC; Wertheimer, FB, 2020)
"Azathioprine (AZA) is a commonly used immunosuppressant in patients with autoimmune diseases."1.56NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series. ( Balasubramanian, P; Devasia, AJ; George, B; Illangeswaran, RSS; Raj, IX, 2020)
"Many patients with immune thrombocytopenia (ITP) may require special attention and long-term treatment."1.48Efficacy and tolerability of old and new drugs used in the treatment of immune thrombocytopenia: Results from a long-term observation in clinical practice. ( Aboud, N; Depré, F; Mayer, B; Salama, A, 2018)
"Interstitial lung disease is a rare but recognised complication of rituximab but has been rarely reported in the setting of ITP."1.38Rituximab-induced interstitial lung disease in a patient with immune thrombocytopenia purpura. ( Berkahn, L; Child, N; O'Carroll, M, 2012)
"Patients with primary immune thrombocytopenia (ITP) may require treatment to reduce the risk of serious bleeding if platelets remain consistently below 30 × 10(9)/L."1.36Should medical treatment options be exhausted before splenectomy is performed in adult ITP patients? A debate. ( Newland, A; Pabinger, I; Stasi, R; Thornton, P, 2010)
"Acute interstitial pneumonitis is the main pulmonary side effect during MTX treatment."1.35[Pneumonitis associated to methotrexate]. ( Marquina Barcos, A; Monón Ballarín, S; Mozota Duarte, J; Ruiz-Ruiz, FJ; Sáenz Abad, D, 2008)
"One patient had immune thrombocytopenia and neutropenia."1.33Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura. ( Andersen, I; Andersen, TM; Birgens, HS; Bjerrum, OW; Braendstrup, P; Clausen, NT; Hansen, PB; Hasselbalch, HC; Jensen, BA; Nielsen, OJ; Pedersen, BB; Peterslund, NA; Plesner, T; Schmidt, K, 2005)
"Sarcoidosis is a chronic granulomatous disorder characterized by multisystem involvement, however, symptomatic thrombocytopenia as a presenting manifestation is rare."1.31Thrombocytopenia as the presenting manifestation of sarcoidosis. ( Agarwal, A; Agarwal, V; Gupta, RK; Mishra, R; Pal, S, 2002)
"Autopsy revealed that the cervical cancer was the primary origin of the liver tumors."1.30[Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura]. ( Kariya, K; Kawamura, S; Munakata, A; Nakahata, R; Takami, H; Tamai, Y; Tsushima, K; Yoshimura, T, 1999)
"A young patient developed chronic idiopathic thrombocytopenic purpura."1.28Defect of platelet aggregation and adhesion induced by autoantibodies against platelet glycoprotein IIIa. ( Balduini, CL; Bellotti, V; Bertolino, G; Mazzini, G; Noris, P; Piovella, F; Samaden, A; Sinigaglia, F; Torti, M, 1992)
"The treatment with azathioprine and prednisolone after IVIG appears to be effective in maintenance of platelet counts."1.28[Effects of maintenance treatment after high-dose intravenous gamma-globulin for idiopathic thrombocytopenic purpura]. ( Fujitake, H; Im, T; Kageyama, T; Kawagoe, H; Kokawa, T; Nomura, S; Ohyabu, H; Park, K; Tatsumi, N; Yasunaga, K, 1991)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.33)18.7374
1990's4 (9.30)18.2507
2000's17 (39.53)29.6817
2010's12 (27.91)24.3611
2020's9 (20.93)2.80

Authors

AuthorsStudies
Mahajna, H3
Verstockt, B3
Bergemalm, D3
Castiglione, F3
Rodríguez-Moranta, F3
Savarino, E3
Hoentjen, F3
Bessissow, T3
Pokryszka, J3
Cremer, A3
Eder, P3
Truyens, M3
Yerushalmy-Feler, A3
García, MJ3
Kopylov, U3
Su, J1
Xu, M1
Dong, Z1
Wang, Q1
Ma, L1
Xiao, P1
Chen, X1
Cvetković, M1
Pantić, N1
Virijević, M1
Pravdić, Z1
Sabljić, N1
Mitrović, M1
Suvajdžić-Vuković, N1
Velayos Jiménez, B1
Cuello García, R1
Del Olmo Martínez, L1
Macho Conesa, A1
Fernández Salazar, L1
Bm, S1
Toshniwal, M1
Bhattacharya, M1
Jakkal, D1
Chon, AH1
Chan, R1
Lee, RH1
Kwong, K1
Wertheimer, FB1
Weitz, IC1
Devasia, AJ1
Illangeswaran, RSS1
Raj, IX1
George, B1
Balasubramanian, P1
Fanouriakis, A1
Tziolos, N1
Bertsias, G1
Boumpas, DT1
Ducassou, S1
Fernandes, H1
Savel, H1
Bertrand, Y1
Leblanc, T1
Abou Chahla, W1
Pasquet, M1
Leverger, G1
Barlogis, V1
Thomas, C1
Bayart, S1
Pellier, I1
Armari-Alla, C1
Guitton, C1
Cheikh, N1
Kherfellah, D1
Vassal, G1
Thiébaut, R1
Laghouati, S1
Aladjidi, N1
Brunet, E1
Martínez de Sola, M1
Garcia-Iglesias, P1
Calvet, X1
Depré, F1
Aboud, N1
Mayer, B1
Salama, A1
Mizuno, S1
Naganuma, M1
Kanai, T1
Chang, H1
Tang, TC1
Hung, YS1
Li, PL1
Kuo, MC1
Wu, JH1
Wang, PN1
Lougaris, V1
Baronio, M1
Gazzurelli, L1
Lorenzini, T1
Fuoti, M1
Moratto, D1
Bozzola, A1
Ricci, C1
Bondioni, MP1
Ravelli, A1
Villanacci, V1
Plebani, A1
Kumwenda, JJ1
Hsiao, CH1
Tseng, KC1
Tseng, CW1
Tung, CH1
Fan, Y1
Chang, NB1
Xing, BL1
Li, YM1
Pei, L1
Li, JT1
Sabnani, I1
Tsang, P1
Valdivieso, R1
Cevallos, F1
Caballero, MT1
Quirce, S1
Arnold, DM1
Nazi, I1
Santos, A1
Chan, H1
Heddle, NM1
Warkentin, TE1
Kelton, JG1
McDonald, EJ1
Butler, A1
Stasi, R1
Newland, A1
Thornton, P1
Pabinger, I2
Child, N1
O'Carroll, M1
Berkahn, L1
Uygur-Bayramiçli, O1
Aydin, D1
Ak, O1
Karadayi, N1
RICHMOND, J1
WOODRUFF, MF1
CUMMING, RA1
DONALD, KW1
Imbach, P1
Tsai, CL1
Lu, TC1
Chen, WJ1
Knecht, H1
Baumberger, M1
Tobòn, A1
Steck, A1
Treppendahl, MB1
Nielsen, OJ2
Braendstrup, P1
Bjerrum, OW1
Jensen, BA1
Clausen, NT1
Hansen, PB1
Andersen, I1
Schmidt, K1
Andersen, TM1
Peterslund, NA1
Birgens, HS1
Plesner, T1
Pedersen, BB1
Hasselbalch, HC1
Simanek, R1
Panzer, S1
Lechner, K1
Reale, LD1
Besa, EC1
Boruchov, DM1
Gururangan, S1
Driscoll, MC1
Bussel, JB1
Fujita, H1
Togami, K1
Mori, M1
Hashimoto, H1
Nagai, K1
Nagai, Y1
Tabata, S1
Kurata, M1
Mastusita, A1
Maeda, A1
Takahashi, T1
Sáenz Abad, D1
Ruiz-Ruiz, FJ1
Monón Ballarín, S1
Mozota Duarte, J1
Marquina Barcos, A1
Fukuda, M1
Horibe, K1
Miyajima, Y1
Matsumoto, K1
Kozaki, T1
Komiyama, A1
Yoshimura, T1
Tamai, Y1
Takami, H1
Kariya, K1
Nakahata, R1
Tsushima, K1
Munakata, A1
Kawamura, S1
Ohmine, K1
Izumi, T1
Muroi, K1
Shimizu, R1
Imagawa, S1
Komatsu, N1
Sasaki, R1
Hatake, K1
Miura, Y1
Ozawa, K1
Agarwal, V1
Pal, S1
Agarwal, A1
Gupta, RK1
Mishra, R1
Balduini, CL1
Bertolino, G1
Noris, P1
Piovella, F1
Sinigaglia, F1
Bellotti, V1
Samaden, A1
Torti, M1
Mazzini, G1
Yasunaga, K1
Kokawa, T1
Fujitake, H1
Nomura, S1
Kageyama, T1
Ohyabu, H1
Tatsumi, N1
Im, T1
Park, K1
Kawagoe, H1
Sousa, FC1
Pinto Medeiros, J1
Marques, R1
Marques-Neves, C1
Matsubara, K1
Nigami, H1
Harigaya, H1
Tanaka, T1
Yura, K1
Nozaki, H1
Iwata, A1
Fukaya, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033]120 participants (Anticipated)Interventional2022-08-15Enrolling by invitation
"French National Cohort of Patients With Pediatric-onset of Autoimmune Cytopenia (OBS'CEREVANCE Cohort)"[NCT05937828]3,500 participants (Anticipated)Observational [Patient Registry]2010-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for azathioprine and Autoimmune Thrombocytopenia

ArticleYear
Relapse of Evans syndrome following BNT162b2 (Pfizer-BioNTech) COVID-19 vaccine: case report and literature review.
    Journal of infection in developing countries, 2023, 06-30, Volume: 17, Issue:6

    Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Bilirubin; BNT162 Vaccine; Chronic Disease; COVID-19; C

2023
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc

2021
Immune thrombocytopenic purpura associated with Crohn's disease with complete response to infliximab.
    Gastroenterologia y hepatologia, 2019, Volume: 42, Issue:1

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Azathioprine; Benzoates; Crohn Disease; Humans; Hydra

2019
Refractory idiopathic immune thrombocytopenic purpura in children: current and future treatment options.
    Paediatric drugs, 2003, Volume: 5, Issue:12

    Topics: Adult; Antibodies, Monoclonal; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Cycloph

2003
Rituximab in autoimmune pancytopenia: a case report and review of literature.
    Annals of hematology, 2007, Volume: 86, Issue:12

    Topics: Adult; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived

2007
[Successful treatment with azathioprine for autoimmune thrombocytopenia developing after autologous peripheral blood stem cell transplantation].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:8

    Topics: Aged; Azathioprine; Humans; Immunosuppressive Agents; Male; Peripheral Blood Stem Cell Transplantati

2007

Trials

3 trials available for azathioprine and Autoimmune Thrombocytopenia

ArticleYear
Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura.
    Blood, 2010, Jan-07, Volume: 115, Issue:1

    Topics: Azathioprine; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppre

2010
Multiagent induction and maintenance therapy for patients with refractory immune thrombocytopenic purpura (ITP).
    Blood, 2007, Nov-15, Volume: 110, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Child; Child, Pr

2007
[Low-dose prednisolone therapy for idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2000, Volume: 41, Issue:1

    Topics: Anti-Inflammatory Agents; Azathioprine; Combined Modality Therapy; Humans; Immunosuppressive Agents;

2000

Other Studies

34 other studies available for azathioprine and Autoimmune Thrombocytopenia

ArticleYear
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
    Journal of Crohn's & colitis, 2023, May-03, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur

2023
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
    Journal of Crohn's & colitis, 2023, May-03, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur

2023
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
    Journal of Crohn's & colitis, 2023, May-03, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur

2023
Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.
    Journal of Crohn's & colitis, 2023, May-03, Volume: 17, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Inflammatory Bowel Diseases; Male; Pur

2023
Efficacy and safety of azathioprine plus prednisone versus prednisone alone as first-line treatment for antinuclear antibody-positive immune thrombocytopenia: a retrospective cohort study.
    Hematology (Amsterdam, Netherlands), 2023, Volume: 28, Issue:1

    Topics: Antibodies, Antinuclear; Azathioprine; Humans; Immunosuppressive Agents; Prednisone; Purpura, Thromb

2023
Immune thrombocytopenic purpura associated with inactive ulcerative colitis in chronic treatment with adalimumab.
    Gastroenterologia y hepatologia, 2020, Volume: 43, Issue:1

    Topics: Adalimumab; Anti-Inflammatory Agents; Azathioprine; Blood Transfusion; Colitis, Ulcerative; Female;

2020
Combination Therapy of Azathioprine+ Dapsone as Effective Second Line Agents for the Treatment of Chronic Immune Thrombocytopenic Purpura.
    The Journal of the Association of Physicians of India, 2020, Volume: 68, Issue:1

    Topics: Anti-Infective Agents; Azathioprine; Combined Modality Therapy; Dapsone; Humans; Immunosuppressive A

2020
Multidrug Therapy for Refractory Immune Thrombocytopenia in Pregnancy.
    Obstetrics and gynecology, 2020, Volume: 135, Issue:3

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Pregnancy;

2020
NUDT15 polymorphism explains serious toxicity to azathioprine in Indian patients with chronic immune thrombocytopenia and autoimmune hemolytic anemia: a case series.
    Drug metabolism and personalized therapy, 2020, 08-24, Volume: 35, Issue:4

    Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Genotype; Humans; Leukopenia; Methyltransferases; Purpu

2020
Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation.
    The Journal of pediatrics, 2021, Volume: 231

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chronic Disease; Female; Humans; Hydroxychloroqui

2021
Efficacy and tolerability of old and new drugs used in the treatment of immune thrombocytopenia: Results from a long-term observation in clinical practice.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Benzoates; Child; Child, Preschool; Combin

2018
Idiopathic Thrombocytopenic Purpura Responsive to Surgery for Crohn's Disease.
    Inflammatory bowel diseases, 2019, 02-21, Volume: 25, Issue:3

    Topics: Adult; Azathioprine; Crohn Disease; Humans; Immunosuppressive Agents; Male; Prognosis; Purpura, Thro

2019
Immune thrombocytopenia: Effectiveness of frontline steroids and comparison of azathioprine, splenectomy, and rituximab as second-line treatment.
    European journal of haematology, 2018, Volume: 101, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Biomarkers; Combined Modality Therapy; Female; Humans;

2018
A de novo monoallelic CTLA-4 deletion causing pediatric onset CVID with recurrent autoimmune cytopenias and severe enteropathy.
    Clinical immunology (Orlando, Fla.), 2018, Volume: 197

    Topics: Adalimumab; Adolescent; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Autoimmune Diseases

2018
A woman with recurrent anaemia and the Malawian health system.
    Malawi medical journal : the journal of Medical Association of Malawi, 2013, Volume: 25, Issue:1

    Topics: Anemia, Hemolytic; Antibodies, Antinuclear; Azathioprine; Clinical Laboratory Services; Coombs Test;

2013
Late-Onset Immune Thrombocytopenic Purpura After Withdrawal of Interferon Treatment for Chronic Hepatitis C Infection: A Case Report.
    Medicine, 2015, Volume: 94, Issue:34

    Topics: Age of Onset; Antiviral Agents; Azathioprine; Glucocorticoids; Hepatitis C, Chronic; Humans; Immunos

2015
[A clinical study of 103 idiopathic thrombocytopenic purpura].
    Zhonghua nei ke za zhi, 2008, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Aged; Aged, 80 and over; Azathioprine; China; Cyclophosphamide; Cyc

2008
Therapeutic implications of T-cell clonopathy of unknown significance in chronic immune thrombocytopenic purpura.
    Platelets, 2009, Volume: 20, Issue:2

    Topics: Adult; Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Purpura, Thr

2009
Chronic urticaria caused by folic acid.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 103, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Drug Hypersensitivity; Female; Folic Acid; Humans

2009
Immune thrombocytopaenia in adults: a single-centre retrospective review of patients presenting over 7 years.
    The New Zealand medical journal, 2010, Apr-09, Volume: 123, Issue:1312

    Topics: Adult; Antibodies, Antinuclear; Antineoplastic Agents, Phytogenic; Azathioprine; Biopsy, Fine-Needle

2010
Should medical treatment options be exhausted before splenectomy is performed in adult ITP patients? A debate.
    Annals of hematology, 2010, Volume: 89, Issue:12

    Topics: Adrenal Cortex Hormones; Azathioprine; Danazol; Humans; Purpura, Thrombocytopenic, Idiopathic; Recep

2010
Rituximab-induced interstitial lung disease in a patient with immune thrombocytopenia purpura.
    Internal medicine journal, 2012, Volume: 42, Issue:3

    Topics: Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Combined Modality Therapy;

2012
Hyperprolactinemia caused by azathioprine.
    Journal of clinical gastroenterology, 2003, Volume: 36, Issue:1

    Topics: Adult; Azathioprine; Female; Hepatitis, Autoimmune; Humans; Hyperprolactinemia; Immunosuppressive Ag

2003
A case of idiopathic thrombocytopenia and autoimmune hemolytic anemia treated with thymic irradiation and by administration of imuran and actinomycin-C.
    Lancet (London, England), 1963, Jul-20, Volume: 2, Issue:7299

    Topics: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Dactinomycin; H

1963
Spontaneous retroperitoneal bleeding in a patient with Evans syndrome.
    Annals of hematology, 2004, Volume: 83, Issue:12

    Topics: Adult; Anemia, Hemolytic; Angiography; Anti-Inflammatory Agents; Antimetabolites; Azathioprine; Fema

2004
Sustained remission of CIDP associated with Evans syndrome.
    Neurology, 2004, Aug-24, Volume: 63, Issue:4

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclon

2004
[Idiopathic thrombocytopenic purpura. A retrospective evaluation of 68 patients].
    Ugeskrift for laeger, 2004, Sep-20, Volume: 166, Issue:39

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Azathioprine; Cyclophospha

2004
Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura.
    American journal of hematology, 2005, Volume: 78, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-D

2005
Late spontaneous remissions in severe adult autoimmune thrombocytopenia.
    Annals of hematology, 2007, Volume: 86, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cohort Studies; Cyclosporine; Female; Humans; Im

2007
[Pneumonitis associated to methotrexate].
    Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Diagnosis, Differential; Female; Humans; Immunosuppressive Ag

2008
[Chronic myelomonocytic leukemia developed 9 years after the diagnosis of idiopathic thrombocytopenic purpura in a child].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1994, Volume: 35, Issue:6

    Topics: Adolescent; Azathioprine; Combined Modality Therapy; Female; Humans; Leukemia, Myelomonocytic, Chron

1994
[Rapidly progressive irradiated cervical cancer that metastasized to the liver during therapy for idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1999, Volume: 40, Issue:2

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Disease Progression; Female; Humans; Immunosuppressiv

1999
Thrombocytopenia as the presenting manifestation of sarcoidosis.
    The Journal of the Association of Physicians of India, 2002, Volume: 50

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Purpura, Thr

2002
Defect of platelet aggregation and adhesion induced by autoantibodies against platelet glycoprotein IIIa.
    Thrombosis and haemostasis, 1992, Aug-03, Volume: 68, Issue:2

    Topics: Adult; Autoantibodies; Azathioprine; Blood Platelet Disorders; Female; Humans; Platelet Adhesiveness

1992
[Effects of maintenance treatment after high-dose intravenous gamma-globulin for idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1991, Volume: 32, Issue:9

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Combined Modality Therapy; Female; gamma-Globulins; Hu

1991
Spontaneous retrobulbar haemorrhage in idiopathic thrombocytopenic purpura.
    BMJ case reports, 2017, Dec-13, Volume: 2017

    Topics: Adrenal Cortex Hormones; Aged, 80 and over; Humans; Intraocular Pressure; Male; Mercaptopurine; Purp

2017
[Combination therapy with low-dose cyclosporin A, azathiopurine, and prednisolone for a child with refractory chronic idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:3

    Topics: Child, Preschool; Chronic Disease; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combina

2007