azathioprine has been researched along with Arthritis, Juvenile in 36 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Arthritis, Juvenile: Arthritis in children, with onset before 16 years of age. The terms juvenile rheumatoid arthritis (JRA) and juvenile idiopathic arthritis (JIA) refer to classification systems for chronic arthritis in children. Only one subtype of juvenile arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the therapeutic value of azathioprine as monotherapy or combined with other immunosuppressive drugs for uveitis in patients with juvenile idiopathic arthritis (JIA)." | 7.77 | Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis. ( Ganser, G; Goebel, JC; Heiligenhaus, A; Heinz, C; Michels, H; Roesel, M, 2011) |
| "To investigate the therapeutic value of azathioprine as monotherapy or combined with other immunosuppressive drugs for uveitis in patients with juvenile idiopathic arthritis (JIA)." | 3.77 | Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis. ( Ganser, G; Goebel, JC; Heiligenhaus, A; Heinz, C; Michels, H; Roesel, M, 2011) |
| "Azathioprine is a useful drug in severe JCA, with a sustained effect and acceptable side effects." | 2.68 | Azathioprine in patients with juvenile chronic arthritis: a longterm followup study. ( Aho, K; Isomäki, H; Kautiainen, H; Savolainen, HA; Verronen, P, 1997) |
| "Thirty-two patients with juvenile rheumatoid arthritis (JRA) entered a comparative, double blind, parallel 16-week clinical trial of azathioprine versus placebo." | 2.66 | Azathioprine versus placebo in patients with juvenile rheumatoid arthritis: a single center double blind comparative study. ( Høyeraal, HM; Kvien, TK; Sandstad, B, 1986) |
| "Following repeated liver biopsy, autoimmune hepatitis was assumed and prednisolone and azathioprine were initiated." | 1.35 | [Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report]. ( Hartmann, U; Reuss-Borst, M; Schmitt, S, 2008) |
| "The diagnoses were juvenile oligoarthritis (n = 6, including two with extended disease), systemic arthritis (n = 2), juvenile spondyloarthropathy (n = 1), and juvenile dermatomyositis (n = 1)." | 1.32 | Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis. ( Job-Deslandre, C; Kahan, A; Sornay-Soares, C, 2004) |
| "Sulfasalazine (SSZ) has recently been shown to be effective for the management of juvenile rheumatoid arthritis (JRA)." | 1.31 | Sulfasalazine therapy for juvenile rheumatoid arthritis. ( Chen, CC; Chiang, BL; Lin, YT; Yang, YH, 2002) |
| " MTX dosage ranged from 0." | 1.30 | The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis. ( Klama, K; Lacki, JK; Mackiewicz, S; Michels, H; Muller, W; Truckenbrodt, H, 1997) |
| "Prednisone (PRED) was discontinued in one case with systemic (JCA) and 0." | 1.27 | Steroid economising effects of a calf thymus extract in three patients with juvenile chronic arthritis. ( Fabricius, HA; Klingshirn, R; Pernice, W; Stahn, R, 1983) |
| "Drug therapy of juvenile rheumatoid arthritis is discussed." | 1.26 | [Drug therapy of juvenile chronic polyarthritis]. ( Suschke, HJ, 1980) |
| "A case of juvenile rheumatoid arthritis with vasculitis is presented." | 1.25 | Digital artery thrombosis and vasculitis in juvenile rheumatoid arthritis. ( Carson, RA, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (61.11) | 18.7374 |
| 1990's | 7 (19.44) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Tanev, D | 1 |
| Peteva, P | 1 |
| Fairbanks, L | 1 |
| Marinaki, A | 1 |
| Ivanova, M | 1 |
| Alaikov, T | 1 |
| Shivarov, V | 1 |
| Nimmrich, S | 1 |
| Horneff, G | 1 |
| Goebel, JC | 1 |
| Roesel, M | 1 |
| Heinz, C | 1 |
| Michels, H | 2 |
| Ganser, G | 1 |
| Heiligenhaus, A | 1 |
| Sornay-Soares, C | 1 |
| Job-Deslandre, C | 1 |
| Kahan, A | 1 |
| Hartmann, U | 1 |
| Schmitt, S | 1 |
| Reuss-Borst, M | 1 |
| Massimo, L | 1 |
| Cottafava, F | 1 |
| Mori, PG | 1 |
| Igari, Y | 1 |
| Mukai, S | 1 |
| Saito, N | 1 |
| Morito, T | 1 |
| Yoshida, H | 1 |
| Kasukawa, R | 1 |
| Pernice, W | 1 |
| Stahn, R | 1 |
| Fabricius, HA | 1 |
| Klingshirn, R | 1 |
| Suschke, HJ | 1 |
| Bacon, BR | 1 |
| Treuhaft, WH | 1 |
| Goodman, AM | 1 |
| Dhib, M | 1 |
| Prieur, AM | 1 |
| Courville, S | 1 |
| Niaudet, P | 1 |
| Francois, A | 1 |
| Godin, M | 1 |
| Fillastre, JP | 1 |
| Haagsma, CJ | 1 |
| van Riel, PL | 1 |
| Lacki, JK | 1 |
| Klama, K | 1 |
| Truckenbrodt, H | 1 |
| Mackiewicz, S | 1 |
| Muller, W | 1 |
| Savolainen, HA | 1 |
| Kautiainen, H | 1 |
| Isomäki, H | 1 |
| Aho, K | 1 |
| Verronen, P | 1 |
| Haas, JP | 1 |
| Höper, K | 1 |
| Leipold, G | 1 |
| Dörr, HG | 1 |
| Höper, J | 1 |
| Singer, NG | 1 |
| McCune, WJ | 1 |
| Kilmartin, DJ | 1 |
| Forrester, JV | 1 |
| Dick, AD | 1 |
| Lin, YT | 2 |
| Yang, YH | 2 |
| Tsai, MJ | 1 |
| Chiang, BL | 2 |
| Chen, CC | 1 |
| Sänger, L | 1 |
| Hollister, JR | 1 |
| Chiossi, FM | 1 |
| Bliddal, H | 1 |
| Helin, P | 1 |
| Dugowson, CE | 1 |
| Gilliland, BC | 1 |
| Kvien, TK | 1 |
| Høyeraal, HM | 1 |
| Sandstad, B | 1 |
| Deicher, H | 1 |
| Stoeber, E | 2 |
| Kölle, G | 5 |
| Graner, HP | 1 |
| Denman, EJ | 1 |
| Denman, AM | 1 |
| Greenwood, BM | 1 |
| Gall, D | 1 |
| Heath, RB | 1 |
| Schöntag, W | 1 |
| Dale, I | 1 |
| Carson, RA | 1 |
| Blichfeldt, P | 1 |
| Pincus, T | 1 |
| Hughes, GR | 1 |
| Pincus, D | 1 |
| Tina, LU | 1 |
| Bellanti, JA | 1 |
4 reviews available for azathioprine and Arthritis, Juvenile
| Article | Year |
|---|---|
Combination of second-line antirheumatic drugs.
Topics: Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cyclosporine; Drug Therapy, Combinat | 1997 |
Update on immunosuppressive therapy.
Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cycl | 1998 |
Immunosuppressant therapy of juvenile rheumatoid arthritis.
Topics: Alkylating Agents; Arthritis, Juvenile; Azathioprine; Cyclophosphamide; Humans; Immunization; Immuno | 1977 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
2 trials available for azathioprine and Arthritis, Juvenile
| Article | Year |
|---|---|
Azathioprine in patients with juvenile chronic arthritis: a longterm followup study.
Topics: Adolescent; Amyloidosis; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Chronic Dis | 1997 |
Azathioprine versus placebo in patients with juvenile rheumatoid arthritis: a single center double blind comparative study.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Clinical Trials as Topic; Do | 1986 |
30 other studies available for azathioprine and Arthritis, Juvenile
| Article | Year |
|---|---|
Beware of the Uric Acid: Severe Azathioprine Myelosuppression in a Patient With Juvenile Idiopathic Arthritis and Hereditary Xanthinuria.
Topics: Aldehyde Oxidase; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Bone Marrow Failure Disor | 2020 |
Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.
Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Ag | 2015 |
Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppre | 2011 |
Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Azathioprine; Child | 2004 |
[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].
Topics: Adalimumab; Adolescent; Alanine Transaminase; Antibodies, Monoclonal; Antibodies, Monoclonal, Humani | 2008 |
[Therapeutic trial of azothioprine (Imuran) in some immunological diseases in children].
Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Arthritis, Juvenile; Azathioprine; Child; Child, Preschoo | 1966 |
[A case of adult onset juvenile rheumatoid arthritis].
Topics: Adult; Age Factors; Arthritis, Juvenile; Azathioprine; Diagnosis, Differential; Humans; Male | 1984 |
Steroid economising effects of a calf thymus extract in three patients with juvenile chronic arthritis.
Topics: Animals; Arthritis, Juvenile; Aspirin; Azathioprine; Cattle; Child; Child, Preschool; Chloroquine; D | 1983 |
[Drug therapy of juvenile chronic polyarthritis].
Topics: Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Glucocorticoids; Gold; Humans; Penicillamine; | 1980 |
Azathioprine-induced pancytopenia. Occurrence in two patients with connective-tissue diseases.
Topics: Adult; Arthritis, Juvenile; Azathioprine; Blood Cell Count; Bone Marrow; Connective Tissue Diseases; | 1981 |
Crescentic glomerulonephritis in juvenile chronic arthritis.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antibody Specificity; Arthritis, Juvenile; Azathioprine; Chi | 1996 |
The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis.
Topics: Adolescent; alpha 1-Antitrypsin; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Chi | 1997 |
Oxygen saturation of intracapillary haemoglobin in patients with systemic JCA (Still's disease).
Topics: Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Capillaries; Child; C | 1997 |
Cyclosporin A therapy in refractory non-infectious childhood uveitis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Chronic Disease; Cyclosporin | 1998 |
Long-term effects of azathioprine therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppre | 2000 |
Sulfasalazine therapy for juvenile rheumatoid arthritis.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Azat | 2002 |
[Therapy of juvenile chronic polyarthritis].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chlo | 1975 |
[Therapy of juvenile rheumatoid arthritis. Personal experience].
Topics: Adrenal Cortex Hormones; Age Factors; Arthritis, Juvenile; Aspirin; Azathioprine; Child; Child, Pres | 1978 |
Leucopenia in adult Still's disease during treatment with azathioprine and sulphasalazine.
Topics: Adult; Arthritis, Juvenile; Aspirin; Azathioprine; Drug Therapy, Combination; Humans; Leukopenia; Ma | 1987 |
[Recommendations for immunosuppressive therapy in systemic lupus erythematosus].
Topics: Adrenocorticotropic Hormone; Antibodies, Antinuclear; Arthritis, Juvenile; Azathioprine; Bone Marrow | 1972 |
[Immunosuppressive therapy in children. 1st experience with azthioprine (Imuran) in Still's syndrome and rheumatoid arthritis].
Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi | 1967 |
Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Antibody Formation; Antigens; Antineoplastic Agents; Arthritis, Juvenile; A | 1970 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chlo | 1970 |
[Immunosuppressive agents in the basic therapy of visceral forms of rheumatoid arthritis in children].
Topics: Adolescent; Adrenal Cortex Hormones; Amyloidosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi | 1972 |
The treatment of rheumatoid arthritis with azathioprine.
Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Male; Nausea | 1972 |
Digital artery thrombosis and vasculitis in juvenile rheumatoid arthritis.
Topics: Arteries; Arteritis; Arthritis, Juvenile; Azathioprine; Blood Vessels; Child, Preschool; Female; Gan | 1973 |
[Drug therapy in juvenile rheumatoid arthritis. Experiences with azathioprine].
Topics: Arthritis, Juvenile; Azathioprine; Bone Marrow Diseases; Child; Child, Preschool; Female; Fever; Hum | 1974 |
[Clinical aspects of immunosuppressive therapy in childhood rheumatoid arthritis].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Arthritis, Juvenile; Azathioprine; Child; Humans; Immuni | 1972 |
[Bone marrow damage following immunosuppressive therapy with azathioprine of juvenile rheumatoid arthritis and the Still syndrome].
Topics: Adolescent; Agranulocytosis; Arthritis, Juvenile; Azathioprine; Bone Marrow Diseases; Bone Marrow Ex | 1969 |
Antibodies to DNA in childhood systemic lupus erythematosus.
Topics: Adolescent; Antibodies; Arthritis, Juvenile; Azathioprine; Carbon Isotopes; Child; Child, Preschool; | 1971 |