Compounds > azathioprine
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azathioprine and Arthritis, Juvenile Chronic

azathioprine has been researched along with Arthritis, Juvenile Chronic in 36 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"To investigate the therapeutic value of azathioprine as monotherapy or combined with other immunosuppressive drugs for uveitis in patients with juvenile idiopathic arthritis (JIA)."7.77Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis. ( Ganser, G; Goebel, JC; Heiligenhaus, A; Heinz, C; Michels, H; Roesel, M, 2011)
"To investigate the therapeutic value of azathioprine as monotherapy or combined with other immunosuppressive drugs for uveitis in patients with juvenile idiopathic arthritis (JIA)."3.77Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis. ( Ganser, G; Goebel, JC; Heiligenhaus, A; Heinz, C; Michels, H; Roesel, M, 2011)
"Azathioprine is a useful drug in severe JCA, with a sustained effect and acceptable side effects."2.68Azathioprine in patients with juvenile chronic arthritis: a longterm followup study. ( Aho, K; Isomäki, H; Kautiainen, H; Savolainen, HA; Verronen, P, 1997)
"Thirty-two patients with juvenile rheumatoid arthritis (JRA) entered a comparative, double blind, parallel 16-week clinical trial of azathioprine versus placebo."2.66Azathioprine versus placebo in patients with juvenile rheumatoid arthritis: a single center double blind comparative study. ( Høyeraal, HM; Kvien, TK; Sandstad, B, 1986)
"Following repeated liver biopsy, autoimmune hepatitis was assumed and prednisolone and azathioprine were initiated."1.35[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report]. ( Hartmann, U; Reuss-Borst, M; Schmitt, S, 2008)
"The diagnoses were juvenile oligoarthritis (n = 6, including two with extended disease), systemic arthritis (n = 2), juvenile spondyloarthropathy (n = 1), and juvenile dermatomyositis (n = 1)."1.32Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis. ( Job-Deslandre, C; Kahan, A; Sornay-Soares, C, 2004)
"Sulfasalazine (SSZ) has recently been shown to be effective for the management of juvenile rheumatoid arthritis (JRA)."1.31Sulfasalazine therapy for juvenile rheumatoid arthritis. ( Chen, CC; Chiang, BL; Lin, YT; Yang, YH, 2002)
" MTX dosage ranged from 0."1.30The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis. ( Klama, K; Lacki, JK; Mackiewicz, S; Michels, H; Muller, W; Truckenbrodt, H, 1997)
"Prednisone (PRED) was discontinued in one case with systemic (JCA) and 0."1.27Steroid economising effects of a calf thymus extract in three patients with juvenile chronic arthritis. ( Fabricius, HA; Klingshirn, R; Pernice, W; Stahn, R, 1983)
"Drug therapy of juvenile rheumatoid arthritis is discussed."1.26[Drug therapy of juvenile chronic polyarthritis]. ( Suschke, HJ, 1980)
"A case of juvenile rheumatoid arthritis with vasculitis is presented."1.25Digital artery thrombosis and vasculitis in juvenile rheumatoid arthritis. ( Carson, RA, 1973)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199022 (61.11)18.7374
1990's7 (19.44)18.2507
2000's4 (11.11)29.6817
2010's2 (5.56)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Tanev, D1
Peteva, P1
Fairbanks, L1
Marinaki, A1
Ivanova, M1
Alaikov, T1
Shivarov, V1
Nimmrich, S1
Horneff, G1
Goebel, JC1
Roesel, M1
Heinz, C1
Michels, H2
Ganser, G1
Heiligenhaus, A1
Sornay-Soares, C1
Job-Deslandre, C1
Kahan, A1
Hartmann, U1
Schmitt, S1
Reuss-Borst, M1
Massimo, L1
Cottafava, F1
Mori, PG1
Igari, Y1
Mukai, S1
Saito, N1
Morito, T1
Yoshida, H1
Kasukawa, R1
Pernice, W1
Stahn, R1
Fabricius, HA1
Klingshirn, R1
Suschke, HJ1
Bacon, BR1
Treuhaft, WH1
Goodman, AM1
Dhib, M1
Prieur, AM1
Courville, S1
Niaudet, P1
Francois, A1
Godin, M1
Fillastre, JP1
Haagsma, CJ1
van Riel, PL1
Lacki, JK1
Klama, K1
Truckenbrodt, H1
Mackiewicz, S1
Muller, W1
Savolainen, HA1
Kautiainen, H1
Isomäki, H1
Aho, K1
Verronen, P1
Haas, JP1
Höper, K1
Leipold, G1
Dörr, HG1
Höper, J1
Singer, NG1
McCune, WJ1
Kilmartin, DJ1
Forrester, JV1
Dick, AD1
Lin, YT2
Yang, YH2
Tsai, MJ1
Chiang, BL2
Chen, CC1
Sänger, L1
Hollister, JR1
Chiossi, FM1
Bliddal, H1
Helin, P1
Dugowson, CE1
Gilliland, BC1
Kvien, TK1
Høyeraal, HM1
Sandstad, B1
Deicher, H1
Stoeber, E2
Kölle, G5
Graner, HP1
Denman, EJ1
Denman, AM1
Greenwood, BM1
Gall, D1
Heath, RB1
Schöntag, W1
Dale, I1
Carson, RA1
Blichfeldt, P1
Pincus, T1
Hughes, GR1
Pincus, D1
Tina, LU1
Bellanti, JA1

Reviews

4 reviews available for azathioprine and Arthritis, Juvenile Chronic

ArticleYear
Combination of second-line antirheumatic drugs.
    Annals of medicine, 1997, Volume: 29, Issue:2

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Cyclosporine; Drug Therapy, Combinat

1997
Update on immunosuppressive therapy.
    Current opinion in rheumatology, 1998, Volume: 10, Issue:3

    Topics: Adult; Arthritis, Juvenile; Azathioprine; Behcet Syndrome; Child; Cladribine; Cyclophosphamide; Cycl

1998
Immunosuppressant therapy of juvenile rheumatoid arthritis.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:2 Suppl

    Topics: Alkylating Agents; Arthritis, Juvenile; Azathioprine; Cyclophosphamide; Humans; Immunization; Immuno

1977
Management of rheumatoid arthritis.
    Disease-a-month : DM, 1986, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc

1986

Trials

2 trials available for azathioprine and Arthritis, Juvenile Chronic

ArticleYear
Azathioprine in patients with juvenile chronic arthritis: a longterm followup study.
    The Journal of rheumatology, 1997, Volume: 24, Issue:12

    Topics: Adolescent; Amyloidosis; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Chronic Dis

1997
Azathioprine versus placebo in patients with juvenile rheumatoid arthritis: a single center double blind comparative study.
    The Journal of rheumatology, 1986, Volume: 13, Issue:1

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Clinical Trials as Topic; Do

1986

Other Studies

30 other studies available for azathioprine and Arthritis, Juvenile Chronic

ArticleYear
Beware of the Uric Acid: Severe Azathioprine Myelosuppression in a Patient With Juvenile Idiopathic Arthritis and Hereditary Xanthinuria.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2020, Volume: 26, Issue:2

    Topics: Aldehyde Oxidase; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Bone Marrow Failure Disor

2020
Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.
    Rheumatology international, 2015, Volume: 35, Issue:3

    Topics: Adalimumab; Adolescent; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antirheumatic Ag

2015
Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:2

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppre

2011
Joint lavage for treating recurrent knee involvement in patients with juvenile idiopathic arthritis.
    Joint bone spine, 2004, Volume: 71, Issue:4

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Azathioprine; Child

2004
[Elevated liver enzymes in rheumatoid arthritis : differential diagnostic considerations based on a case report].
    Zeitschrift fur Rheumatologie, 2008, Volume: 67, Issue:5

    Topics: Adalimumab; Adolescent; Alanine Transaminase; Antibodies, Monoclonal; Antibodies, Monoclonal, Humani

2008
[Therapeutic trial of azothioprine (Imuran) in some immunological diseases in children].
    Minerva pediatrica, 1966, Nov-10, Volume: 18, Issue:34

    Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Arthritis, Juvenile; Azathioprine; Child; Child, Preschoo

1966
[A case of adult onset juvenile rheumatoid arthritis].
    Ryumachi. [Rheumatism], 1984, Volume: 24, Issue:5

    Topics: Adult; Age Factors; Arthritis, Juvenile; Azathioprine; Diagnosis, Differential; Humans; Male

1984
Steroid economising effects of a calf thymus extract in three patients with juvenile chronic arthritis.
    Klinische Wochenschrift, 1983, Apr-15, Volume: 61, Issue:8

    Topics: Animals; Arthritis, Juvenile; Aspirin; Azathioprine; Cattle; Child; Child, Preschool; Chloroquine; D

1983
[Drug therapy of juvenile chronic polyarthritis].
    Fortschritte der Medizin, 1980, May-29, Volume: 98, Issue:20

    Topics: Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Glucocorticoids; Gold; Humans; Penicillamine;

1980
Azathioprine-induced pancytopenia. Occurrence in two patients with connective-tissue diseases.
    Archives of internal medicine, 1981, Volume: 141, Issue:2

    Topics: Adult; Arthritis, Juvenile; Azathioprine; Blood Cell Count; Bone Marrow; Connective Tissue Diseases;

1981
Crescentic glomerulonephritis in juvenile chronic arthritis.
    The Journal of rheumatology, 1996, Volume: 23, Issue:9

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antibody Specificity; Arthritis, Juvenile; Azathioprine; Chi

1996
The effect of methotrexate and azathioprine on the serum levels of IgA-alpha 1-antitrypsin complex in juvenile chronic arthritis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1997, Volume: 30, Issue:6

    Topics: Adolescent; alpha 1-Antitrypsin; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Child; Chi

1997
Oxygen saturation of intracapillary haemoglobin in patients with systemic JCA (Still's disease).
    Advances in experimental medicine and biology, 1997, Volume: 428

    Topics: Analysis of Variance; Antirheumatic Agents; Arthritis, Juvenile; Azathioprine; Capillaries; Child; C

1997
Cyclosporin A therapy in refractory non-infectious childhood uveitis.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:7

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Chronic Disease; Cyclosporin

1998
Long-term effects of azathioprine therapy for juvenile rheumatoid arthritis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2000, Volume: 99, Issue:4

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppre

2000
Sulfasalazine therapy for juvenile rheumatoid arthritis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2002, Volume: 101, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Azat

2002
[Therapy of juvenile chronic polyarthritis].
    Deutsche medizinische Wochenschrift (1946), 1975, Oct-03, Volume: 100, Issue:40

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chlo

1975
[Therapy of juvenile rheumatoid arthritis. Personal experience].
    Minerva pediatrica, 1978, Nov-30, Volume: 30, Issue:22

    Topics: Adrenal Cortex Hormones; Age Factors; Arthritis, Juvenile; Aspirin; Azathioprine; Child; Child, Pres

1978
Leucopenia in adult Still's disease during treatment with azathioprine and sulphasalazine.
    Clinical rheumatology, 1987, Volume: 6, Issue:2

    Topics: Adult; Arthritis, Juvenile; Aspirin; Azathioprine; Drug Therapy, Combination; Humans; Leukopenia; Ma

1987
[Recommendations for immunosuppressive therapy in systemic lupus erythematosus].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Adrenocorticotropic Hormone; Antibodies, Antinuclear; Arthritis, Juvenile; Azathioprine; Bone Marrow

1972
[Immunosuppressive therapy in children. 1st experience with azthioprine (Imuran) in Still's syndrome and rheumatoid arthritis].
    Munchener medizinische Wochenschrift (1950), 1967, Sep-15, Volume: 109, Issue:37

    Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi

1967
Failure of cytotoxic drugs to suppress immune responses of patients with rheumatoid arthritis.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Aged; Antibody Formation; Antigens; Antineoplastic Agents; Arthritis, Juvenile; A

1970
[Long term therapy of rheumatoid arthritis in children].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chlo

1970
[Immunosuppressive agents in the basic therapy of visceral forms of rheumatoid arthritis in children].
    Medizinische Klinik, 1972, Apr-28, Volume: 67, Issue:17

    Topics: Adolescent; Adrenal Cortex Hormones; Amyloidosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathi

1972
The treatment of rheumatoid arthritis with azathioprine.
    Scandinavian journal of rheumatology, 1972, Volume: 1, Issue:3

    Topics: Adolescent; Arthritis, Juvenile; Azathioprine; Child; Child, Preschool; Female; Humans; Male; Nausea

1972
Digital artery thrombosis and vasculitis in juvenile rheumatoid arthritis.
    Canadian Medical Association journal, 1973, Sep-01, Volume: 109, Issue:5

    Topics: Arteries; Arteritis; Arthritis, Juvenile; Azathioprine; Blood Vessels; Child, Preschool; Female; Gan

1973
[Drug therapy in juvenile rheumatoid arthritis. Experiences with azathioprine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1974, Jun-30, Volume: 94, Issue:18

    Topics: Arthritis, Juvenile; Azathioprine; Bone Marrow Diseases; Child; Child, Preschool; Female; Fever; Hum

1974
[Clinical aspects of immunosuppressive therapy in childhood rheumatoid arthritis].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Arthritis, Juvenile; Azathioprine; Child; Humans; Immuni

1972
[Bone marrow damage following immunosuppressive therapy with azathioprine of juvenile rheumatoid arthritis and the Still syndrome].
    Deutsche medizinische Wochenschrift (1946), 1969, Oct-31, Volume: 94, Issue:44

    Topics: Adolescent; Agranulocytosis; Arthritis, Juvenile; Azathioprine; Bone Marrow Diseases; Bone Marrow Ex

1969
Antibodies to DNA in childhood systemic lupus erythematosus.
    The Journal of pediatrics, 1971, Volume: 78, Issue:6

    Topics: Adolescent; Antibodies; Arthritis, Juvenile; Azathioprine; Carbon Isotopes; Child; Child, Preschool;

1971