azathioprine has been researched along with Arteriosclerosis in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/kg/day+azathioprine 2 mg/kg/day) on rat cytomegalovirus (RCMV)-enhanced allograft arteriosclerosis was investigated applying WF (AG-B2, RT1v) recipients of DA (AG-B4, RT1a) aortic allografts." | 3.69 | Triple drug immunosuppression significantly reduces immune activation and allograft arteriosclerosis in cytomegalovirus-infected rat aortic allografts and induces early latency of viral infection. ( Bruggeman, CA; Bruning, JH; Häyry, PJ; Lautenschlager, IT; Lemström, KB, 1994) |
| "Tacrolimus has improved hyperlipidaemia in our cyclosporin previously treated patients and increased the resistance to oxidation of high and low-density lipoproteins." | 1.31 | [Effect of cyclosporin and tacrolimus on lipoprotein oxidation after renal transplantation]. ( Alsina, J; Fiol, C; Gil-Vernet, S; Gómez-Gerique, N; Grinyó, JM; Hurtado, I; Martínez Castelao, A; Ramos, R; Sabaté, I; Serón, D; Yzaguirre, MT, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 12 (60.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prüfer, J | 1 |
| Schuchardt, M | 1 |
| Tölle, M | 1 |
| Prüfer, N | 1 |
| Höhne, M | 1 |
| Zidek, W | 1 |
| van der Giet, M | 1 |
| Martínez Castelao, A | 1 |
| Ramos, R | 1 |
| Serón, D | 1 |
| Gil-Vernet, S | 1 |
| Fiol, C | 1 |
| Gómez-Gerique, N | 1 |
| Yzaguirre, MT | 1 |
| Hurtado, I | 1 |
| Sabaté, I | 1 |
| Alsina, J | 1 |
| Grinyó, JM | 1 |
| Mitnick, H | 1 |
| Jacobowitz, G | 1 |
| Krinsky, G | 1 |
| Eberle, M | 1 |
| Rosenzweig, B | 1 |
| Willis, D | 1 |
| Rockman, C | 1 |
| Riles, T | 1 |
| Kotyla, PJ | 1 |
| Sliwińska-Kotyla, B | 1 |
| Lewicki, M | 1 |
| Kucharz, EJ | 1 |
| Hilbrands, LB | 1 |
| Demacker, PN | 1 |
| Hoitsma, AJ | 1 |
| Stalenhoef, AF | 1 |
| Koene, RA | 1 |
| Wahlers, T | 1 |
| Mügge, A | 1 |
| Oppelt, P | 1 |
| Heublein, B | 1 |
| Fieguth, HG | 1 |
| Jurmann, M | 1 |
| Haverich, A | 1 |
| Lemström, KB | 2 |
| Bruning, JH | 1 |
| Bruggeman, CA | 1 |
| Lautenschlager, IT | 1 |
| Häyry, PJ | 2 |
| Livi, U | 1 |
| Luciani, GB | 1 |
| Boffa, GM | 1 |
| Faggian, G | 1 |
| Bortolotti, U | 1 |
| Thiene, G | 1 |
| Mazzucco, A | 1 |
| Räisänen-Sokolowski, AK | 1 |
| Koskinen, PK | 1 |
| Jacobs, U | 1 |
| Klein, B | 1 |
| Miersch, WD | 1 |
| Molitor, D | 1 |
| Klehr, HU | 1 |
| Cantarovich, M | 1 |
| Latter, DA | 1 |
| Loertscher, R | 1 |
| Allegra, A | 1 |
| Corica, F | 1 |
| Ientile, R | 1 |
| Corsonello, A | 1 |
| Sparacino, V | 1 |
| Accettola, F | 1 |
| Caputo, F | 1 |
| Macaione, S | 1 |
| Buemi, M | 1 |
| Quaschning, T | 1 |
| Mainka, T | 1 |
| Nauck, M | 1 |
| Rump, LC | 1 |
| Wanner, C | 1 |
| Krämer-Guth, A | 1 |
| Mennander, A | 2 |
| Paavonen, T | 2 |
| Häyry, P | 2 |
| Tiisala, S | 1 |
| Halttunen, J | 1 |
| Gossard, D | 1 |
| Langlais, J | 1 |
| Lower, RR | 1 |
| Graham, AF | 1 |
| Rider, AK | 1 |
| Caves, PK | 1 |
| Stinson, EB | 1 |
| Harrison, DC | 1 |
| Shumway, NE | 1 |
| Schroeder, JS | 1 |
| Hollander, CF | 1 |
| Chatty, ME | 1 |
| Deodhar, SD | 1 |
2 reviews available for azathioprine and Arteriosclerosis
| Article | Year |
|---|---|
[Risk of atherosclerosis development in patients with systemic lupus erythematosus].
Topics: Adrenal Cortex Hormones; Arteriosclerosis; Autoantibodies; Azathioprine; Blood Coagulation Disorders | 2005 |
Current status of clinical cardiac transplantation.
Topics: Adult; Arteriosclerosis; Azathioprine; B-Lymphocytes; Brain Death; Cardiac Catheterization; Cardiomy | 1974 |
3 trials available for azathioprine and Arteriosclerosis
| Article | Year |
|---|---|
The effects of cyclosporine and prednisone on serum lipid and (apo)lipoprotein levels in renal transplant recipients.
Topics: Adult; Apolipoproteins; Arteriosclerosis; Azathioprine; Cholesterol, HDL; Cyclosporine; Female; Graf | 1995 |
Coronary vasculopathy following cardiac transplantation and cyclosporine immunosuppression: preventive treatment with angiopeptin, a somatostatin analog.
Topics: Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Coronary Disease; Cyclosporine; Female; Heart | 1994 |
Immunosuppression enhances atherogenicity of lipid profile after transplantation.
Topics: Apolipoproteins B; Arteriosclerosis; Azathioprine; Cholesterol, VLDL; Cyclosporine; Drug Therapy, Co | 1999 |
15 other studies available for azathioprine and Arteriosclerosis
| Article | Year |
|---|---|
Harmful effects of the azathioprine metabolite 6-mercaptopurine in vascular cells: induction of mineralization.
Topics: Animals; Aorta; Arteriosclerosis; Azathioprine; Calcium; Disease Progression; Mercaptopurine; Minera | 2014 |
[Effect of cyclosporin and tacrolimus on lipoprotein oxidation after renal transplantation].
Topics: Adult; Antihypertensive Agents; Apolipoproteins B; Arteriosclerosis; Azathioprine; Cholesterol; Cycl | 2002 |
Periaortitis: gadolinium-enhanced magnetic resonance imaging and response to therapy in four patients.
Topics: Aged; Anti-Inflammatory Agents; Arteriosclerosis; Azathioprine; Contrast Media; Female; Gadolinium D | 2004 |
Triple drug immunosuppression significantly reduces immune activation and allograft arteriosclerosis in cytomegalovirus-infected rat aortic allografts and induces early latency of viral infection.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Azathioprine; Cell Division; Cyclosporine; Cytomegalovir | 1994 |
Clinical results of steroid-free induction immunosuppression after heart transplantation.
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Bacterial Infections; | 1993 |
Triple drug immunosuppression significantly reduces aortic allograft arteriosclerosis in the rat.
Topics: Animals; Aorta; Aortic Diseases; Arteriosclerosis; Azathioprine; Cell Division; Cyclosporine; Down-R | 1996 |
Dilemma: maintenance therapy enhances sclerogenic risk profile.
Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Arteriosclerosis; Azathioprine; Cholesterol; Cort | 1996 |
Treatment of steroid-resistant and recurrent acute cardiac transplant rejection with a short course of antibody therapy.
Topics: Acute Disease; Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Bacterial Infections; Biopsy; C | 1997 |
Plasma (total and ionized), erythrocyte and platelet magnesium levels in renal transplant recipients during cyclosporine and/or azathioprine treatment.
Topics: Arteriosclerosis; Azathioprine; Blood Platelets; Cyclosporine; Erythrocytes; Female; Humans; Immunos | 1998 |
Cyclosporine-induced endothelialitis and accelerated arteriosclerosis in chronic allograft rejection.
Topics: Animals; Aorta; Arteriosclerosis; Azathioprine; Cyclosporine; Endothelium, Vascular; Graft Rejection | 1992 |
Chronic rejection of rat aortic allograft. II. Administration of cyclosporin induces accelerated allograft arteriosclerosis.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Azathioprine; Cyclosporine; Disease Models, Animal; Drug | 1991 |
Transplantation and lipids.
Topics: Arteriosclerosis; Azathioprine; Cyclosporins; Humans; Hypercholesterolemia; Lipid Metabolism; Postop | 1991 |
Acute rejection in the long-term cardiac transplant survivor. Clinical diagnosis, treatment and significance.
Topics: Arteriosclerosis; Azathioprine; Biopsy; Coronary Disease; Cyclophosphamide; Electrocardiography; End | 1974 |
Cardiac allograft pathology in Rhesus monkeys.
Topics: Animals; Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Coronary Disease; Coronary Vessels; G | 1973 |
Myocardial changes and kidney transplantation. Lesions in patients receiving immunosuppressive therapy.
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Arteriosclerosis; Autopsy; Azathioprine; Candida; Car | 1969 |