azathioprine has been researched along with Aplasia Pure Red Cell in 30 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " She went into hematological remission 6 weeks following 40 mg/day treatment with prednisolone, but the anemia relapsed frequently when the dosage was lessened." | 2.38 | [Chronic T-cell lymphoproliferative disorder associated with pure red cell aplasia]. ( Akihama, T; Chubachi, A; Endo, Y; Kuwayama, A; Miura, A; Yoshida, K, 1989) |
| " Although megaloblastic change is frequent, reportedly seen in 16% to 82% of bone marrow aspirates, long-term use of azathioprine rarely causes severe anemia." | 1.32 | Azathioprine-induced pure red cell aplasia: case report and review. ( Agrawal, A; Augustine, T; Parrott, NR; Riad, HN, 2004) |
| "Azathioprine is an immunosuppressor drug widely used in the treatment of autoimmune diseases." | 1.31 | [Aplasia after azathioprine administration: role of the thiopurine methyltransferase genetic polymorphism]. ( Baiget, M; Corominas, H; Díaz, C; Domènech, M; González-Juan, D; González-Suárez, B; Pujol, J; Vázquez, G, 2000) |
| "We describe a patient with mixed connective tissue disease (MCTD), who developed pure red cell aplasia which responded favorably during treatment with corticosteroids." | 1.28 | Pure red cell aplasia in mixed connective tissue disease. ( Jäntti, J; Julkunen, H; Pettersson, T, 1989) |
| "The thymoma was removed: after the operation no improvement of her anaemic condition was observed and colony growth was very poor, although T-depleted narrow preparations showed a modest BFU-E formation in autologous serum." | 1.27 | Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment. ( Dalton, R; Eridani, S; Sawyer, B; Whitehead, S, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (26.67) | 18.7374 |
| 1990's | 12 (40.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Rao, A | 1 |
| Rao, R | 1 |
| Kounatidis, D | 1 |
| Vallianou, N | 1 |
| Daskalaki, V | 1 |
| Masaoutis, C | 1 |
| Margellou, E | 1 |
| Harhalakis, N | 1 |
| Kokkinakis, E | 1 |
| Koduri, PR | 1 |
| Vanajakshi, S | 1 |
| Anuradha, R | 1 |
| Kessler, C | 1 |
| Tschumi, S | 1 |
| Simonetti, GD | 1 |
| Bianchetti, MG | 1 |
| Chihara, D | 1 |
| Takeoka, T | 1 |
| Shirase, T | 1 |
| Kishimoto, W | 1 |
| Arimoto-Miyamoto, K | 1 |
| Tsuji, M | 1 |
| Ohno, T | 1 |
| Gardiner, SJ | 1 |
| Gearry, RB | 1 |
| Burt, MJ | 1 |
| Chalmers-Watson, T | 1 |
| Chapman, BA | 1 |
| Ross, AG | 1 |
| Stedman, CA | 1 |
| Huelsen, A | 1 |
| Barclay, ML | 1 |
| Suto, M | 1 |
| Nagai, Y | 1 |
| Hasegawa, M | 1 |
| Handa, H | 1 |
| Ishikawa, O | 1 |
| Agrawal, A | 1 |
| Parrott, NR | 1 |
| Riad, HN | 1 |
| Augustine, T | 1 |
| Casadevall, N | 1 |
| Lacombe, C | 1 |
| Varet, B | 1 |
| Creemers, GJ | 1 |
| van Boven, WP | 1 |
| Lowenberg, B | 1 |
| van der Heul, C | 1 |
| Agarwal, SK | 1 |
| Mittal, D | 1 |
| Tiwari, SC | 1 |
| Dash, SC | 1 |
| Saxena, S | 1 |
| Saxena, R | 1 |
| Mehta, SN | 1 |
| Pruijt, JF | 1 |
| Haanen, JB | 1 |
| Hollander, AA | 1 |
| den Ottolander, GJ | 1 |
| Mukaida, T | 1 |
| Aoe, M | 1 |
| Yamashita, M | 1 |
| Date, H | 1 |
| Ando, A | 1 |
| Shimizu, N | 1 |
| Zazgornik, J | 1 |
| Agarwal, AK | 1 |
| Yadav, R | 1 |
| Jain, A | 1 |
| Sangla, KS | 1 |
| Arora, V | 1 |
| Walia, M | 1 |
| Higashida, K | 1 |
| Kobayashi, K | 1 |
| Sugita, K | 1 |
| Karakida, N | 1 |
| Nakagomi, Y | 1 |
| Sawanobori, E | 1 |
| Sata, Y | 1 |
| Aihara, M | 1 |
| Amemiya, S | 1 |
| Nakazawa, S | 1 |
| Corominas, H | 1 |
| Domènech, M | 1 |
| González-Juan, D | 1 |
| González-Suárez, B | 1 |
| Díaz, C | 1 |
| Pujol, J | 1 |
| Vázquez, G | 1 |
| Baiget, M | 1 |
| Fisch, P | 1 |
| Handgretinger, R | 1 |
| Schaefer, HE | 1 |
| Tohda, S | 1 |
| Nara, N | 1 |
| Tanikawa, S | 1 |
| Imai, Y | 1 |
| Murakami, N | 1 |
| Aoki, N | 1 |
| Vogt, B | 1 |
| Fivush, BA | 1 |
| Schaffner, A | 1 |
| Thomann, B | 1 |
| Zala, GF | 1 |
| Rüegg, R | 1 |
| Keusch, G | 1 |
| Fehr, J | 1 |
| Gmür, J | 1 |
| Takahashi, M | 1 |
| Nikkuni, K | 1 |
| Tanaka, I | 1 |
| Furukawa, T | 1 |
| Moriyama, Y | 1 |
| Shibata, A | 1 |
| Satoh, S | 1 |
| Kuwabara, Y | 1 |
| Maruyama, Y | 1 |
| Matsunaga, Y | 1 |
| Smith, N | 1 |
| Boughton, BJ | 1 |
| Chubachi, A | 1 |
| Yoshida, K | 1 |
| Endo, Y | 1 |
| Miura, A | 1 |
| Akihama, T | 1 |
| Kuwayama, A | 1 |
| Tefferi, A | 1 |
| Windebank, KP | 1 |
| Veeder, MH | 1 |
| Kiely, JM | 1 |
| Julkunen, H | 1 |
| Jäntti, J | 1 |
| Pettersson, T | 1 |
| Eridani, S | 1 |
| Whitehead, S | 1 |
| Sawyer, B | 1 |
| Dalton, R | 1 |
| Rodrigues, JF | 1 |
| Harth, M | 1 |
| Barr, RM | 1 |
| Firkin, FC | 1 |
| Maher, D | 1 |
| Idel'son, LI | 1 |
| Pivnik, AV | 1 |
| Kolesnikova, AS | 1 |
| Grechikhina, EN | 1 |
| Ter-Grigorov, VS | 1 |
4 reviews available for azathioprine and Aplasia Pure Red Cell
| Article | Year |
|---|---|
Azathioprine-associated pure red cell aplasia in renal transplant recipients: a report of two cases.
Topics: Adult; Azathioprine; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantati | 2014 |
Azathioprine-induced pure red-cell aplasia.
Topics: Azathioprine; Diabetic Nephropathies; Female; Humans; Kidney Transplantation; Middle Aged; Red-Cell | 1996 |
Pure red cell aplasia.
Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Azathioprine; Bone Marrow Cells; Fancon | 2000 |
[Chronic T-cell lymphoproliferative disorder associated with pure red cell aplasia].
Topics: Adult; Azathioprine; Combined Modality Therapy; Cyclophosphamide; Female; Humans; Lymphoproliferativ | 1989 |
1 trial available for azathioprine and Aplasia Pure Red Cell
| Article | Year |
|---|---|
Cyclosporine in the treatment of azathioprine-induced red cell aplasia following renal transplantation.
Topics: Adult; Azathioprine; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney | 1992 |
25 other studies available for azathioprine and Aplasia Pure Red Cell
| Article | Year |
|---|---|
Recurrent Pregnancy-Related Pure Red Cell Aplasia Responsive to Combined Corticosteroid and Azathioprine Therapy: A Management Dilemma
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Pregnancy; | 2020 |
Pure Red Cell Aplasia Caused by Azathioprine.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Female; Humans; Male; Red-Cell Aplasia, Pure | 2020 |
New-onset bone marrow aplasia in a 15-year-old adolescent with pauci-immune crescentic glomerulonephritis: Questions.
Topics: Adolescent; Azathioprine; Bone Marrow; Drug Hypersensitivity; Glomerulonephritis; Humans; Immunosupp | 2015 |
Progressive multifocal leukoencephalopathy in myelodysplastic syndrome involving pure red cell aplasia.
Topics: Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multi | 2010 |
Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio.
Topics: Adult; Allopurinol; Anti-Inflammatory Agents; Azathioprine; Biotransformation; Drug Therapy, Combina | 2011 |
Azathioprine-induced pure red cell aplasia in a systemic sclerosis patient with interstitial pneumonia.
Topics: Adult; Azathioprine; Female; Humans; Immunosuppressive Agents; Lung Diseases, Interstitial; Red-Cell | 2011 |
Azathioprine-induced pure red cell aplasia: case report and review.
Topics: Azathioprine; Creatinine; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transpla | 2004 |
[Erythroblastopenia: chronic idiopathic or associated with chronic lymphoid leukemia. Value of cultures of erythroblastic progenitors and therapeutic strategy].
Topics: Adrenal Cortex Hormones; Adult; Antilymphocyte Serum; Azathioprine; Cells, Cultured; Chronic Disease | 1993 |
Azathioprine-associated pure red cell aplasia.
Topics: Adult; Azathioprine; Female; Humans; Kidney Transplantation; Red-Cell Aplasia, Pure | 1993 |
Azathioprine-induced pure red blood cell aplasia in a renal transplant recipient.
Topics: Adult; Azathioprine; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Red-Cell Aplasia | 1993 |
[Four cases of thymoma associated with pure red cell aplasia].
Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 1997 |
Azathioprine induced macrocytosis and red cell aplasia in renal transplant patients.
Topics: Anemia, Macrocytic; Azathioprine; Humans; Immunosuppressive Agents; Kidney Transplantation; Red-Cell | 1997 |
Primary pure red cell aplasia.
Topics: Adolescent; Azathioprine; Biopsy; Bone Marrow; Dose-Response Relationship, Drug; Drug Administration | 1997 |
Pure red blood cell aplasia during azathioprine therapy associated with parvovirus B19 infection.
Topics: Azathioprine; Child; Female; Humans; Immunosuppressive Agents; Parvoviridae Infections; Parvovirus B | 1997 |
[Aplasia after azathioprine administration: role of the thiopurine methyltransferase genetic polymorphism].
Topics: Adult; Azathioprine; Crohn Disease; Humans; Immunosuppressive Agents; Male; Methyltransferases; Poly | 2000 |
Pure red cell aplasia following autoimmune haemolytic anaemia. Cell-mediated suppression of erythropoiesis as a possible pathogenesis of pure red cell aplasia.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Azathioprine; Bone Marrow; Colony-Forming Units Assay; Cytotox | 1992 |
Transient pure red cell aplasia caused by antilymphoblast globulin after cadaveric renal transplantation.
Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Blood Cell Count; Cadaver; Erythropoies | 1991 |
Serum erythropoietic inhibitors in patients with pure red cell aplasia.
Topics: Adult; Aged; Antigens, Viral; Azathioprine; Blood Proteins; Child; Colony-Forming Units Assay; Compl | 1991 |
Azathioprine as possible explanation of etiology of pure red cell aplasia in myasthenics.
Topics: Adult; Azathioprine; Female; Humans; Myasthenia Gravis; Red-Cell Aplasia, Pure; Thymoma | 1989 |
Steroid-responsive pure red cell aplasia associated with natural killer cell lymphocytosis.
Topics: Azathioprine; Blood Transfusion; Erythrocyte Transfusion; Female; Humans; Killer Cells, Natural; Lym | 1989 |
Pure red cell aplasia in mixed connective tissue disease.
Topics: Adult; Azathioprine; Female; Humans; Methylprednisolone; Mixed Connective Tissue Disease; Red-Cell A | 1989 |
Pure red cell aplasia and thymoma: demonstration of persisting inhibition of erythropoiesis after thymectomy and resolution after immune suppressive treatment.
Topics: Antibody Formation; Azathioprine; Bone Marrow Cells; Colony-Forming Units Assay; Erythropoiesis; Fem | 1986 |
Pure red cell aplasia in rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Drug Therapy, | 1988 |
Cytotoxic immunosuppressive drug treatment strategy in pure red cell aplasia.
Topics: Aged; Azathioprine; Combined Modality Therapy; Cyclophosphamide; Female; Hemoglobins; Humans; Male; | 1988 |
[Remission in partial red cell aplasia achieved using a treatment with cyclosporin A].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Therapy; Cycl | 1988 |