azathioprine has been researched along with Anus Diseases in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Anus Diseases: Diseases involving the ANUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease." | 9.10 | Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003) |
| "To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease." | 5.10 | Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003) |
| "It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different." | 2.35 | Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975) |
| "There was the assumption that Crohn's disease (CD) patients with perianal lesions might have different clinical courses compared to those without." | 1.48 | Effects of Perianal Involvement on Clinical Outcomes in Crohn's Disease over 10 Years. ( Cheon, JH; Kim, TI; Kim, WH; Park, SJ; Yoon, JY, 2018) |
| "There is a reported association with Crohn's disease." | 1.46 | Ano-genital Granulomatosis and Crohn's Disease: A Case Series of Males Presenting with Genital Lymphoedema. ( Alexakis, C; Chong, H; Gordon, K; Mellor, R; Mortimer, P; Pollok, R, 2017) |
| "Appropriate treatment of perianal fistulas in Crohn's disease (CD) involves accurate anatomic evaluation." | 1.38 | Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy. ( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012) |
| "Age of onset, surgical past history of Crohn's disease, colonic or ileal involvement, or Harvey-Bradshaw score were not different between groups." | 1.30 | Anal lesions: any significant prognosis in Crohn's disease? ( Bretagne, JF; Gosselin, M; Juguet, F; Mary, JY; Mortaji, A; Siproudhis, L, 1997) |
| "The outcome of treatment of perianal Crohn's disease was assessed in 127 patients." | 1.29 | Perianal Crohn's disease--is it all bad news? ( Keenan, RA; McKee, RF, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (30.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Sousa Magalhães, R | 1 |
| Xavier, S | 1 |
| Cúrdia Gonçalves, T | 1 |
| Dias de Castro, F | 1 |
| Rosa, B | 1 |
| Moreira, MJ | 1 |
| Cotter, J | 1 |
| Yoon, JY | 1 |
| Cheon, JH | 1 |
| Park, SJ | 1 |
| Kim, TI | 1 |
| Kim, WH | 1 |
| Matnani, R | 1 |
| Peker, D | 1 |
| Chhaya, V | 1 |
| Saxena, S | 1 |
| Cecil, E | 1 |
| Subramanian, V | 1 |
| Curcin, V | 1 |
| Majeed, A | 1 |
| Pollok, RC | 1 |
| Alexakis, C | 1 |
| Gordon, K | 1 |
| Mellor, R | 1 |
| Chong, H | 1 |
| Mortimer, P | 1 |
| Pollok, R | 1 |
| Fraser, D | 1 |
| Boyle, S | 1 |
| Amft, N | 1 |
| Lakatos, PL | 1 |
| Czegledi, Z | 1 |
| Szamosi, T | 1 |
| Banai, J | 1 |
| David, G | 1 |
| Zsigmond, F | 1 |
| Pandur, T | 1 |
| Erdelyi, Z | 1 |
| Gemela, O | 1 |
| Papp, J | 1 |
| Lakatos, L | 1 |
| Alvarez, JA | 1 |
| Bermejo, F | 1 |
| Algaba, A | 1 |
| Hernandez, MP | 1 |
| Grau, M | 1 |
| Lahat, A | 1 |
| Assulin, Y | 1 |
| Beer-Gabel, M | 1 |
| Chowers, Y | 1 |
| Lecomte, T | 1 |
| Contou, JF | 1 |
| Beaugerie, L | 1 |
| Carbonnel, F | 1 |
| Cattan, S | 1 |
| Gendre, JP | 1 |
| Cosnes, J | 1 |
| Dejaco, C | 1 |
| Harrer, M | 1 |
| Waldhoer, T | 1 |
| Miehsler, W | 1 |
| Vogelsang, H | 1 |
| Reinisch, W | 1 |
| Singleton, JW | 1 |
| McKee, RF | 1 |
| Keenan, RA | 1 |
| Siproudhis, L | 1 |
| Mortaji, A | 1 |
| Mary, JY | 1 |
| Juguet, F | 1 |
| Bretagne, JF | 1 |
| Gosselin, M | 1 |
| Jeshion, WC | 1 |
| Larsen, KL | 1 |
| Jawad, AF | 1 |
| Piccoli, DA | 1 |
| Verma, R | 1 |
| Maller, ES | 1 |
| Baldassano, RN | 1 |
| Ament, ME | 1 |
| Goligher, JC | 1 |
| de Dombal, FT | 1 |
| Burton, I | 1 |
| Javett, SL | 1 |
| Kavin, H | 1 |
| Bremner, CG | 1 |
| Schneider, J | 1 |
| Levine, E | 1 |
| Hinder, RA | 1 |
| Karayannopoulos, S | 1 |
| Chazan, BI | 1 |
| Hancock, DM | 1 |
| Kempsey, EP | 1 |
| Lennard-Jones, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Fistulous Crohn's Disease by Implant of Autologous Mesenchymal Stem Cells Derived From Adipose Tissue[NCT01157650] | Phase 1/Phase 2 | 15 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| Investigation of Sexual Function in Crohn's Disease Patients With Perianal Fistulas[NCT01635543] | 0 participants (Actual) | Observational | 2011-10-31 | Withdrawn (stopped due to This study was terminated due to some challenges in recruitment process) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for azathioprine and Anus Diseases
| Article | Year |
|---|---|
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy; | 1975 |
Crohn's disease, with special reference to surgical management.
Topics: Abdomen; Anus Diseases; Azathioprine; Barium Sulfate; Colitis, Ulcerative; Crohn Disease; Diagnosis, | 1972 |
1 trial available for azathioprine and Anus Diseases
| Article | Year |
|---|---|
Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anus Diseases; Azathioprine; | 2003 |
17 other studies available for azathioprine and Anus Diseases
| Article | Year |
|---|---|
Does Perianal Disease Influence the Efficacy of Combination Therapy in Crohn's Disease?
Topics: Adult; Anal Canal; Anus Diseases; Azathioprine; Crohn Disease; Drug Therapy, Combination; Endoscopy, | 2021 |
Effects of Perianal Involvement on Clinical Outcomes in Crohn's Disease over 10 Years.
Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Anus Diseases; Azathioprine; Crohn Disease; Disease Prog | 2018 |
Azathioprine induced Epstein Barr virus-positive mucocutaneous ulcer arising in perianal fistula and abscess associated with Crohn's disease.
Topics: Abscess; Anus Diseases; Azathioprine; Crohn Disease; Herpesvirus 4, Human; Humans; Immunosuppressive | 2014 |
Impact of timing and duration of thiopurine treatment on first perianal surgery in Crohn's disease: UK population-based study (1995-2009).
Topics: Adolescent; Adult; Anus Diseases; Azathioprine; Crohn Disease; Digestive System Surgical Procedures; | 2015 |
Ano-genital Granulomatosis and Crohn's Disease: A Case Series of Males Presenting with Genital Lymphoedema.
Topics: Adolescent; Adult; Aged; Anus Diseases; Azathioprine; Child; Crohn Disease; Genital Diseases, Male; | 2017 |
Perianal Crohn Disease after Treatment with Rituximab for Active Granulomatosis with Polyangiitis.
Topics: Antibodies, Monoclonal, Murine-Derived; Anus Diseases; Azathioprine; Biopsy, Needle; Crohn Disease; | 2016 |
Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease.
Topics: Adult; Anus Diseases; Azathioprine; Biomarkers; Crohn Disease; Disease Progression; Female; Humans; | 2009 |
Surgical repair and biological therapy for fecal incontinence in Crohn's disease involving both sphincter defects and complex fistulas.
Topics: Abscess; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Anus Diseases; Azathioprine; Crohn | 2011 |
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy.
Topics: Abscess; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory | 2012 |
Predictive factors of response of perianal Crohn's disease to azathioprine or 6-mercaptopurine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anus Diseases; Azathioprine; Confidence Intervals; Crohn | 2003 |
Medical therapy of inflammatory bowel disease.
Topics: Acute Disease; Adjuvants, Immunologic; Anus Diseases; Azathioprine; Colitis, Ulcerative; Crohn Disea | 1980 |
Perianal Crohn's disease--is it all bad news?
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Antimetabolites; Antitrichomona | 1996 |
Anal lesions: any significant prognosis in Crohn's disease?
Topics: Adolescent; Adult; Aged; Anus Diseases; Azathioprine; Crohn Disease; Female; Fissure in Ano; Humans; | 1997 |
Azathioprine and 6-mercaptopurine for the treatment of perianal Crohn's disease in children.
Topics: Adolescent; Anus Diseases; Azathioprine; Chi-Square Distribution; Child; Child, Preschool; Crohn Dis | 2000 |
Some aspects of Crohn's disease.
Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise | 1973 |
Anorectal Crohn's disease.
Topics: Adult; Aged; Anus Diseases; Azathioprine; Biopsy; Crohn Disease; Female; Humans; Male; Middle Aged; | 1972 |
Azathioprine in the treatment of Crohn's disease.
Topics: Adolescent; Adult; Aged; Anus Diseases; Azathioprine; Barium Sulfate; Colon; Crohn Disease; Female; | 1972 |