Page last updated: 2024-10-23

azathioprine and Aneuploid

azathioprine has been researched along with Aneuploid in 2 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Micronuclei (MN) obtained from mouse bone marrow cells, in vivo exposed to 3 typical clastogens (procarbazine, azathioprine, ethyl methanesulfonate) and 3 typical aneuploidogens (vinblastine, tubulazole, colchicine), were examined for C-band, area and DNA content."3.68Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow. ( Deleener, A; Kirsch-Volders, M; Van Hummelen, P; Vanparys, P, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Hummelen, P1
Deleener, A1
Vanparys, P2
Kirsch-Volders, M1
Vermeiren, F1
Sysmans, M1
Temmerman, R1

Other Studies

2 other studies available for azathioprine and Aneuploid

ArticleYear
Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow.
    Mutation research, 1992, Volume: 271, Issue:1

    Topics: Aneuploidy; Animals; Azacitidine; Azathioprine; Bone Marrow; Chromosome Banding; Colchicine; Dioxola

1992
The micronucleus assay as a test for the detection of aneugenic activity.
    Mutation research, 1990, Volume: 244, Issue:2

    Topics: Aneuploidy; Animals; Azathioprine; Bone Marrow; Cell Division; Colchicine; Cyclophosphamide; Dioxola

1990