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azathioprine and Anemia, Macrocytic

azathioprine has been researched along with Anemia, Macrocytic in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Anemia, Macrocytic: Anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (MCV) and increased mean corpuscular hemoglobin (MCH).

Research Excerpts

ExcerptRelevanceReference
"In an open, randomised, controlled follow-up study the effectiveness of continuous azathioprine therapy of multiple sclerosis with a dosage of 2 mg/kg/day was tested against a control group that was not treated with cytostatics."9.05Azathioprine in treatment of multiple sclerosis. Final results of a 41/2-year controlled study of its effectiveness covering 115 patients. ( Hecker, H; Patzold, U; Pocklington, P, 1982)
"In an open, randomised, controlled follow-up study the effectiveness of continuous azathioprine therapy of multiple sclerosis with a dosage of 2 mg/kg/day was tested against a control group that was not treated with cytostatics."5.05Azathioprine in treatment of multiple sclerosis. Final results of a 41/2-year controlled study of its effectiveness covering 115 patients. ( Hecker, H; Patzold, U; Pocklington, P, 1982)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DUNEA, G1
NAKAMOTO, S1
STRAFFON, RA1
FIGUEROA, JE1
VERSACI, AA1
SHIBAGAKI, M1
KOLFF, WJ1
Lennard, L1
Murphy, MF1
Maddocks, JL1
Patzold, U1
Hecker, H1
Pocklington, P1
Reinicke, H1
Weber, FW1
Hausamen, TU1
Taguchi, H1
Yoshimoto, S1
Machida, K1
Yorimitsu, Y1
Niiya, K1
Shiomi, F1
Ueda, N1
Zazgornik, J1
Torres, L1
Trubowitz, S1
Davis, S1
Wilmanns, W1
Raman, SB1
Abraham, JP1
Saeed, SM1
Sawdyk, M1
Klippel, JH1
Decker, JL1
Roman, J1
Wheby, MS1
Atuk, NO1
Westervelt, FB1
McNicol, GP1
Davies, JA1
Platzer, S1
Asamer, H1
Födisch, HJ1
Gabl, F1
Huber, H1
Judmaier, G1
Spath, P1
Dume, T1
Pöttgen, W1
Christoph, R1
Pirnay, D1
Hartl, W1

Reviews

1 review available for azathioprine and Anemia, Macrocytic

ArticleYear
Advances in medicine.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Anemia, Macrocytic; Anti-Arrhythmia Agents; Anticoagulants; Azathioprine; Chemical and Drug Induced

1972

Trials

1 trial available for azathioprine and Anemia, Macrocytic

ArticleYear
Azathioprine in treatment of multiple sclerosis. Final results of a 41/2-year controlled study of its effectiveness covering 115 patients.
    Journal of the neurological sciences, 1982, Volume: 54, Issue:3

    Topics: Adult; Anemia, Macrocytic; Azathioprine; Clinical Trials as Topic; Female; Hepatitis; Humans; Male;

1982

Other Studies

13 other studies available for azathioprine and Anemia, Macrocytic

ArticleYear
RENAL HOMOTRANSPLANTATION IN 24 PATIENTS.
    British medical journal, 1965, Jan-02, Volume: 1, Issue:5426

    Topics: Anemia; Anemia, Macrocytic; Antineoplastic Agents; Azathioprine; Blood Group Incompatibility; Cadave

1965
Severe megaloblastic anaemia associated with abnormal azathioprine metabolism.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:2

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Azathioprine; Guanine Nucleotides; Humans; Male; Middle A

1984
[Myelosuppression with macrocytic anaemia and leucopenia during treatment with azathioprine in myasthenia gravis].
    Deutsche medizinische Wochenschrift (1946), 1982, Oct-22, Volume: 107, Issue:42

    Topics: Allopurinol; Anemia, Macrocytic; Azathioprine; Drug Interactions; Female; Humans; Leukopenia; Middle

1982
[A case of megaloblastic anemia induced by azathioprine (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1980, Volume: 21, Issue:5

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Azathioprine; Female; Humans; Purpura, Thrombocyto

1980
Azathioprine induced macrocytosis and red cell aplasia in renal transplant patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:3

    Topics: Anemia, Macrocytic; Azathioprine; Humans; Immunosuppressive Agents; Kidney Transplantation; Red-Cell

1997
Case report. Azathioprine-induced megaloblastic erythropoiesis.
    The Journal of the Medical Society of New Jersey, 1978, Volume: 75, Issue:4

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Azathioprine; Erythropoiesis; Female; Humans; Male

1978
[Drug induced megaloblastic anemia].
    Haematology and blood transfusion, 1978, Volume: 21

    Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Ma

1978
Azathioprine-induced reversible severe dyserythropoiesis as a cause of anemia.
    Henry Ford Hospital medical journal, 1986, Volume: 34, Issue:3

    Topics: Adult; Anemia, Macrocytic; Azathioprine; Erythropoiesis; Female; Humans

1986
Relative macrocytosis in cyclophosphamide and azathioprine therapy.
    JAMA, 1974, Jul-08, Volume: 229, Issue:2

    Topics: Anemia, Macrocytic; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Examination; Cyclophosphamide;

1974
Anemias with renal transplantation.
    JAMA, 1972, Sep-11, Volume: 221, Issue:11

    Topics: Anemia, Macrocytic; Azathioprine; Humans; Kidney Transplantation; Leucovorin; Mercaptopurine; Transp

1972
[Correlation of clinical and morphological parameters in chronic hepatitis during long-term treatment with azathioprine].
    Wiener klinische Wochenschrift, 1973, Jul-20, Volume: 85, Issue:29

    Topics: Adult; Anemia, Macrocytic; Autoantibodies; Azathioprine; Chronic Disease; Female; Follow-Up Studies;

1973
[Isolated damage of erythropoiesis during immunosuppressive therapy following kidney transplantation].
    Deutsche medizinische Wochenschrift (1946), 1970, Apr-24, Volume: 95, Issue:17

    Topics: Adult; Anemia, Macrocytic; Azathioprine; Erythrocyte Count; Erythropoiesis; Female; Humans; Immunosu

1970
[Megaloblastic anemia following treatment of rheumatoid arthritis with azathioprine].
    Die Medizinische Welt, 1971, Nov-13, Volume: 46

    Topics: Adult; Anemia, Macrocytic; Arthritis, Rheumatoid; Azathioprine; Humans; Male

1971