Compounds > azathioprine
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azathioprine and Anemia, Hypoplastic

azathioprine has been researched along with Anemia, Hypoplastic in 34 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)."7.70Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000)
"Azathioprine (AZA) is an immunosuppressant that is widely used to treat many disease states including rheumatoid arthritis."4.12A case of azathioprine-induced aplastic anemia. ( Agarwal, AM; Lim, MY; Montgomery, HD, 2022)
"This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)."3.70Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000)
"Azathioprine-induced aplastic anemia and fatal myelosuppression is a rare occurrence in patients with systemic lupus erythematosus (SLE)."2.49Aplastic anemia secondary to azathioprine in systemic lupus erythematosus: report of a case with normal thiopurine S-methyltransferase enzyme activity and review of the literature. ( Afkhami, M; Brynes, RK; Quismorio, FP; Yeter, KC, 2013)
"From 1967 to 1972, 70 patients with aplastic anemia were observed and followed up to death or at least two years."1.25[Course and prognosis of panmyelopathy and isolated aplastic anemia. Retrospective study in 70 patients]. ( Heimpel, H; Rehbock, C; van Eimeren, W, 1975)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199026 (76.47)18.7374
1990's1 (2.94)18.2507
2000's3 (8.82)29.6817
2010's2 (5.88)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Montgomery, HD1
Agarwal, AM1
Lim, MY1
Madrazo, L1
Jones, E1
Hsia, CC1
Yeter, KC1
Afkhami, M1
Brynes, RK1
Quismorio, FP1
Al Riyami, AZ1
Jacobson, K1
Ford, J1
Dalal, BI1
Sudhir, RR1
Rao, SK1
Shanmugam, MP1
Padmanabhan, P1
Reményi, P1
Masszi, T1
Borbényi, Z1
Soós, J1
Siklós, L1
Engelhardt, JI1
Miescher, PA1
Beris, P1
DeClerck, YA1
Ettenger, RB1
Ortega, JA1
Pennisi, AJ1
Flury, W1
Montandon, A1
Hogge, DE1
Wilson, DR1
Shumak, KH1
Cattran, DC1
De Lord, C1
Marsh, JC1
Smith, JG1
Singer, CR1
Gordon-Smith, EC1
Epstein, JB1
Nantel, S1
Sheoltch, SM1
Storb, R1
Gordon, MY1
Kobashi, H2
Miyoshi, I1
Tsubota, T1
Kitajima, K1
Kimura, I1
Asano, K1
Fox, RM1
Firkin, FC1
Arimori, S1
Nakata, Y1
Tada, S1
Koriyama, K1
Ichikawa, Y1
Mitsuhashi, A1
Iwasaki, I1
Hiraki, K1
Mocelin, AJ1
Hager, ET1
Carpenter, CB1
Merrill, JP1
Glogner, P1
Heni, N1
Bruntsch, U1
Gallmeier, WM1
Burkhardt, R1
Schmidt, CG1
Heimpel, H1
Rehbock, C1
van Eimeren, W1
Zaents, SD1
Krants, SB1
Götze, C1
Schäfer, KH1
Retik, AB1
Dubernard, JM1
Hester, WJ1
Murray, JE1
Böttiger, LE1
Rausing, A1
Szulczyńska, K1
Marmont, A1
Gori, E1
Hoensch, H1
Hartwich, G1
Bach, JF1
Dardenne, M1
Bach, MA1
Böttcher, D1
Maas, D1
Wendt, F1
Schubothe, H1
Safdar, SH1
Krantz, SB1
Brown, EB1
Wranne, L1
Bonnevier, JO1
Killander, A1
Killander, J1
Kardaszewicz, E1
Japa, J1
Jameson, S1

Reviews

3 reviews available for azathioprine and Anemia, Hypoplastic

ArticleYear
Aplastic anemia secondary to azathioprine in systemic lupus erythematosus: report of a case with normal thiopurine S-methyltransferase enzyme activity and review of the literature.
    Lupus, 2013, Volume: 22, Issue:14

    Topics: Anemia, Aplastic; Azathioprine; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Lupus Eryth

2013
Immunosuppressive therapy in the treatment of autoimmune diseases.
    Springer seminars in immunopathology, 1984, Volume: 7, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Alkylating Agents; Anemia; Anemia, Aplastic; Anemia, Hemolytic,

1984
Bone marrow transplantation for the treatment of aplastic anemia and acute leukemia.
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Acute Disease; Anemia, Aplastic; Azathioprine; Blood Platelets; Blood Transfusion; Bone Marrow Trans

1978

Other Studies

31 other studies available for azathioprine and Anemia, Hypoplastic

ArticleYear
A case of azathioprine-induced aplastic anemia.
    International journal of laboratory hematology, 2022, Volume: 44, Issue:6

    Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Azathioprine; Genetic Testing; Humans; Immunosuppressive Ag

2022
Azathioprine-induced severe anemia potentiated by the concurrent use of allopurinol.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2021, 01-18, Volume: 193, Issue:3

    Topics: Allopurinol; Anemia, Aplastic; Azathioprine; Bile Duct Diseases; Erythrocyte Transfusion; Gout Suppr

2021
Transient appearance of GPI-deficient population in a patient with azathioprine-associated bone marrow aplasia.
    Annals of hematology, 2012, Volume: 91, Issue:10

    Topics: Anemia, Aplastic; Azathioprine; Child; Glycosylphosphatidylinositols; Hemoglobinuria, Paroxysmal; Hu

2012
Bilateral macular hemorrhage caused by azathioprine-induced aplastic anemia in a corneal graft recipient.
    Cornea, 2002, Volume: 21, Issue:7

    Topics: Adult; Anemia, Aplastic; Azathioprine; Corneal Transplantation; Fundus Oculi; Humans; Immunosuppress

2002
CIDP cured by allogeneic hematopoietic stem cell transplantation.
    European journal of neurology, 2007, Volume: 14, Issue:8

    Topics: Adult; Alopecia; Anemia, Aplastic; Azathioprine; Cyclophosphamide; Female; Graft vs Host Disease; He

2007
Macrocytosis and pure RBC anemia caused by azathioprine.
    American journal of diseases of children (1960), 1980, Volume: 134, Issue:4

    Topics: Adolescent; Adult; Anemia, Aplastic; Azathioprine; Child; Female; Humans; Kidney Transplantation; Ma

1980
[Isolated erythroid aplasia during immunosuppressive therapy with azathioprine after kidney transplantation].
    Schweizerische medizinische Wochenschrift, 1980, Nov-01, Volume: 110, Issue:44

    Topics: Adult; Anemia, Aplastic; Azathioprine; Cyclophosphamide; Glomerulonephritis; Hemoglobins; Humans; Im

1980
Reversible azathioprine-induced erythrocyte aplasia in a renal transplant recipient.
    Canadian Medical Association journal, 1982, Mar-01, Volume: 126, Issue:5

    Topics: Adult; Anemia, Aplastic; Azathioprine; Female; Humans; Kidney Transplantation; Leukopenia

1982
Fatal autoimmune pancytopenia following bone marrow transplantation for aplastic anaemia.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Aspergillosis; Autoantibodies; Autoimmune Di

1996
Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease.
    Bone marrow transplantation, 2000, Volume: 25, Issue:6

    Topics: Administration, Topical; Adult; Anemia, Aplastic; Azathioprine; Bone Marrow Transplantation; Candidi

2000
Circulating inhibitors of granulopoiesis in patients with aplastic anaemia.
    British journal of haematology, 1978, Volume: 39, Issue:4

    Topics: Anemia, Aplastic; Antilymphocyte Serum; Azathioprine; Bone Marrow; Bone Marrow Cells; Cells, Culture

1978
[Recovery from atypical hypoplastic anemia after treatment with azathioprine (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:4

    Topics: Adult; Anemia, Aplastic; Azathioprine; Humans; Male

1979
Sequential pure red cell and megakaryocyte aplasia associated with chronic liver disease and ulcerative colitis.
    American journal of hematology, 1978, Volume: 4, Issue:1

    Topics: Adolescent; Anemia, Aplastic; Azathioprine; Chronic Disease; Colitis, Ulcerative; Cyclophosphamide;

1978
[A case of thymoma with myasthenia gravis and pure red cell aplasia treated with thymectomy and azathioprine (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1978, Apr-10, Volume: 67, Issue:4

    Topics: Aged; Anemia, Aplastic; Azathioprine; Humans; Male; Myasthenia Gravis; Thymectomy; Thymoma; Thymus N

1978
[Medullar aplasia due to concomitant use of azathioprine and allopurinol in kidney transplantation. Probable beneficial effects of infusion of leukemic cells].
    AMB : revista da Associacao Medica Brasileira, 1976, Volume: 22, Issue:5

    Topics: Adult; Allopurinol; Anemia, Aplastic; Azathioprine; Blood Transfusion; Drug Interactions; Humans; Ki

1976
[Pancytopenia following combination treatment with allopurinol and azathioprine].
    Die Medizinische Welt, 1976, Aug-13, Volume: 27, Issue:33

    Topics: Allopurinol; Anemia, Aplastic; Azathioprine; Drug Interactions; Drug Therapy, Combination; Gout; Hum

1976
[Immunosuppressive therapy in pure red cell aplasia].
    Deutsche medizinische Wochenschrift (1946), 1975, Jan-17, Volume: 100, Issue:3

    Topics: Adult; Anabolic Agents; Anemia, Aplastic; Antibody Formation; Antilymphocyte Serum; Azathioprine; Cy

1975
[Course and prognosis of panmyelopathy and isolated aplastic anemia. Retrospective study in 70 patients].
    Blut, 1975, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Anabolic Agents; Anemia, Aplastic; Azathioprine; Bone Marrow E

1975
[Erythroblastophthisis].
    Problemy gematologii i perelivaniia krovi, 1975, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Aged; Androgens; Anemia, Aplastic; Azathioprine; Chronic Disease; Cyclophosphamid

1975
[Successful immunosuppressive treatment of a pancytopathy with positive LE phenomenon induced by ethosuccinimide].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:8

    Topics: Anemia, Aplastic; Antibodies, Antinuclear; Antigens; Antimetabolites; Autoantibodies; Azathioprine;

1970
A study of the effects of intra-arterial immunosuppressive drug therapy on canine renal allografts.
    Surgery, 1966, Volume: 60, Issue:6

    Topics: Anemia, Aplastic; Animals; Azaserine; Azathioprine; Dactinomycin; Dogs; Drug Synergism; Injections,

1966
Pure red cell anemia: immunosuppressive treatment.
    Annals of internal medicine, 1972, Volume: 76, Issue:4

    Topics: Adult; Anemia, Aplastic; Azathioprine; Blood Cell Count; Bone Marrow Examination; Erythrocytes; Eryt

1972
[Use of immunosuppressive drugs in bronchial asthma (author's transl)].
    Przeglad lekarski, 1973, Volume: 30, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Asthma; Azathioprine; Female; Humans; Male; Middle

1973
[Pure erythroblastic aplasia associated with thymoma in an adult. Complete remission after immunodepressive therapy].
    Minerva medica, 1973, Sep-05, Volume: 64, Issue:61

    Topics: Anemia, Aplastic; Azathioprine; Cyclophosphamide; Hemangiosarcoma; Humans; Immunosuppressive Agents;

1973
[Pancytopenia and bone-marrow changes in chronic active hepatitis].
    Deutsche medizinische Wochenschrift (1946), 1972, Oct-06, Volume: 97, Issue:40

    Topics: Adult; Aged; Anemia, Aplastic; Azathioprine; Bone Marrow Examination; Chronic Disease; Female; Hepat

1972
[Determination of active metabolites of immunosuppressive agents in the serum. Application to azathioprine].
    La Nouvelle presse medicale, 1972, Oct-07, Volume: 1, Issue:35

    Topics: Anemia, Aplastic; Azathioprine; Gout; Hepatitis; Histocompatibility Testing; Humans; Immune Adherenc

1972
[Anemia caused by erythroblastopenia in adult age].
    Klinische Wochenschrift, 1970, Jan-15, Volume: 48, Issue:2

    Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti

1970
Successful immunosuppressive treatment of erythroid aplasia appearing after thymectomy.
    British journal of haematology, 1970, Volume: 19, Issue:4

    Topics: Anemia, Aplastic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Cyclophosphamide; Erythropoies

1970
Pure red-cell anaemia with pro-erythroblast maturation arrest.
    Scandinavian journal of haematology, 1970, Volume: 7, Issue:2

    Topics: Anemia, Aplastic; Azathioprine; Blood Cell Count; Child, Preschool; Erythropoiesis; Hemoglobins; Hum

1970
[Effect of long-term immunosuppressive treatment on the hematopoietic system].
    Polskie Archiwum Medycyny Wewnetrznej, 1970, Volume: 45, Issue:5

    Topics: Anemia, Aplastic; Azathioprine; Hematopoiesis; Hematopoietic System; Humans; Immunosuppressive Agent

1970
[Immunosuppressive treatment of aplastic anemia--a case report].
    Nordisk medicin, 1970, Dec-03, Volume: 84, Issue:49

    Topics: Anemia, Aplastic; Anti-Bacterial Agents; Azathioprine; Blood Transfusion; Bone Marrow Cells; Cycloph

1970