azathioprine has been researched along with Allergy, Drug in 123 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter." | 9.04 | Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975) |
| "Azathioprine (AZA) drug hypersensitivity reaction (DHR) is an uncommon yet potentially lethal condition that often goes unrecognised in patients with anti-Neutrophil Cytoplasmic Antibody (ANCA) associated vasculitis (AAV)." | 8.31 | Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis. ( Au Peh, C; Carroll, RP; Fleet, AP; Hissaria, P; Salehi, T, 2023) |
| "Erythema nodosum and pustules are rarely reported manifestations of azathioprine hypersensitivity." | 7.74 | Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. ( Aractingi, S; Beaugerie, L; Cosnes, J; de Fonclare, AL; Duriez, P; Khosrotehrani, K, 2007) |
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 7.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "The association of fever, nasal congestion and reversible rise in serum creatinine in a patient receiving azathioprine is reported." | 7.68 | Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy. ( Donckerwolcke, RA; Vande Walle, JG, 1990) |
| "We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency." | 7.68 | Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992) |
| "Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills." | 7.68 | Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990) |
| "A patient with myasthenia gravis is described who exhibited hypersensitivity including an apparent acute exacerbation of the underlying disorder when treated with azathioprine." | 7.67 | Hypersensitivity to azathioprine in myasthenia gravis. ( Corston, R; Watts, GF, 1984) |
| "We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder." | 7.65 | Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975) |
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 5.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| "Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis." | 5.33 | Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 5.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 5.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| "Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter." | 5.04 | Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975) |
| "Azathioprine (AZA) drug hypersensitivity reaction (DHR) is an uncommon yet potentially lethal condition that often goes unrecognised in patients with anti-Neutrophil Cytoplasmic Antibody (ANCA) associated vasculitis (AAV)." | 4.31 | Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis. ( Au Peh, C; Carroll, RP; Fleet, AP; Hissaria, P; Salehi, T, 2023) |
| "Erythema nodosum and pustules are rarely reported manifestations of azathioprine hypersensitivity." | 3.74 | Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. ( Aractingi, S; Beaugerie, L; Cosnes, J; de Fonclare, AL; Duriez, P; Khosrotehrani, K, 2007) |
| " Azathioprine has a significant early adverse reaction (EAR) profile, which includes an acute syndrome of constitutional symptoms, fever, rash, and acute pancreatitis and often requires discontinuation of drug." | 3.73 | Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience. ( Bajaj, JS; Binion, DG; Emmons, J; Franco, J; Knox, JF; Levy, M; Podoll, J; Saeian, K; Varma, RR, 2005) |
| "Approximately 10% of inflammatory bowel disease (IBD) patients receiving 6-mercaptopurine (6-MP) or azathioprine (AZA) develop drug hypersensitivity reactions necessitating early discontinuation of these traditional thiopurines." | 3.72 | Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. ( Abreu, MT; Dubinsky, MC; Feldman, EJ; Targan, SR; Vasiliauskas, EA, 2003) |
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 3.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "We describe a patient with rheumatoid arthritis (RA) who developed hypersensitivity after 3 weeks of therapy with azathioprine with fever, jaundice and renal insufficiency." | 3.68 | Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity. ( Devogelaer, JP; Geubel, A; Meys, E; Nagant de Deuxchaisnes, C; Rahier, J, 1992) |
| "Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills." | 3.68 | Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990) |
| "The association of fever, nasal congestion and reversible rise in serum creatinine in a patient receiving azathioprine is reported." | 3.68 | Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy. ( Donckerwolcke, RA; Vande Walle, JG, 1990) |
| "A patient with myasthenia gravis is described who exhibited hypersensitivity including an apparent acute exacerbation of the underlying disorder when treated with azathioprine." | 3.67 | Hypersensitivity to azathioprine in myasthenia gravis. ( Corston, R; Watts, GF, 1984) |
| "We describe an unusual hypersensitivity reaction to azathioprine occurring in a patient with dermatomyositis, in which the acute manifestations suggested an exacerbation of the patient's underlying disorder." | 3.65 | Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis. ( Goldenberg, DL; Stor, RA, 1975) |
| "Autoimmune hepatitis is a rare chronic inflammatory liver disease, affecting all ages, characterised by elevated transaminase and immunoglobulin G levels, positive autoantibodies, interface hepatitis at liver histology and good response to immunosuppressive treatment." | 2.55 | Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments. ( Mieli-Vergani, G; Terziroli Beretta-Piccoli, B; Vergani, D, 2017) |
| "Azathioprine is a drug commonly used for the treatment of inflammatory bowel disease, organ transplantation and various autoimmune diseases." | 2.40 | Cholestatic hepatocellular injury with azathioprine: a case report and review of the mechanisms of hepatotoxicity. ( Jewell, L; Lalor, E; Romagnuolo, J; Sadowski, DC; Thomson, AB, 1998) |
| " Adverse effects occur in about 15% of patients." | 2.40 | Azathioprine in inflammatory bowel disease, a safe alternative? ( Tanis, AA, 1998) |
| "Azathioprine was discontinued and an evaluation for sepsis was undertaken; all cultures were negative and the fever abated." | 2.39 | Azathioprine hypersensitivity-like reactions--a case report and a review of the literature. ( Gupta, AK; Knowles, SR; Sauder, D; Shear, NH, 1995) |
| "Our aim was to assess the cost-effectiveness of phenotyping-based dosing of TPMT activity, genotyping-based screening and no screening (reference) for patients treated with azathioprine." | 1.51 | Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis. ( Chatellier, G; Durand-Zaleski, I; Loriot, MA; Pallet, N; Zarca, K, 2019) |
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 1.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| " This study aims to detect TPMT polymorphisms and TPMT enzyme activity in Chinese SLE patients and to describe the association between TPMT genotypes and adverse effects of AZA." | 1.40 | Association of thiopurine methyltransferase status with azathioprine side effects in Chinese patients with systemic lupus erythematosus. ( Chen, D; Lian, F; Liang, L; Qiu, Q; Wang, Y; Xu, H; Yang, X; Ye, Y; Yuan, S; Zhan, Z, 2014) |
| "We describe a pediatric case of Sweet syndrome presenting 10 days after treatment with azathioprine." | 1.37 | Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis. ( Choe, YH; Jang, KT; Kim, MJ, 2011) |
| "Mercaptopurine was tolerated in 71% (12/17) with hepatotoxicity and in 68% (13/19) with arthralgia/myalgia during azathioprine treatment." | 1.35 | Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease. ( Almer, SH; Eriksson, A; Hindorf, U; Johansson, M; Kvifors, E, 2009) |
| "Sweet syndrome is a reactive, sterile, pustular dermatosis that occurs in association with infection, malignancy, or connective tissue disease or in response to the use of certain medications." | 1.35 | Sweet syndrome as a manifestation of azathioprine hypersensitivity. ( Brunner, KL; El-Azhary, RA; Gibson, LE, 2008) |
| "Twenty nine previously confirmed Crohn's disease (CD) (n = 14) and ulcerative colitis (UC) (n = 15) patients with a known previous (AZA) hypersensitivity reaction were studied prospectively." | 1.35 | Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease. ( Farkas, K; Lonovics, J; Molnar, T; Nagy, F; Nyari, T; Szepes, Z, 2008) |
| "Mercaptopurine was tolerated by 59% (36 of 61) of azathioprine-intolerant patients (median dose 1." | 1.35 | Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease. ( Arnott, ID; Hansoti, B; Lees, CW; Maan, AK; Satsangi, J, 2008) |
| "Two patients developed acute pancreatitis." | 1.34 | Thiopurine metabolite monitoring in paediatric inflammatory bowel disease. ( Bohane, TD; Day, AS; Lee, D; Naidoo, D; Ooi, CY, 2007) |
| " These observations suggest that the development of muscular weakness in patients on azathioprine should be considered as an adverse effect of the drug." | 1.33 | Severe muscular weakness: an unusual adverse effect of azathioprine therapy. ( Arora, M; Dutta, SK; Karhadkar, AS; Schwartz, HJ, 2006) |
| "Her renal biopsy showed acute tubulointerstitial nephritis and no active glomerulonephritis." | 1.33 | Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. ( Bir, K; Carette, S; Herzenberg, AM, 2006) |
| "Azathioprine was considered responsible for these two adverse reactions (shock) as an allergen." | 1.31 | [Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine]. ( Kawano, F; Kiyokawa, T; Sanada, I; Tsukamoto, A, 2000) |
| "Dapsone was the most commonly used drug (51 patients), followed by methotrexate (24 patients), azathioprine (23 patients), and cyclophosphamide (15 patients); prednisone, always given as adjunctive treatment, was used in 17 patients." | 1.31 | The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid. ( Ahmed, AR; Baltatzis, S; Foster, CS; Miserocchi, E; Roque, MR, 2002) |
| "A 40-year-old white man with ulcerative colitis, treated with chronic mesalamine and occasional steroids, was admitted to the hospital with a 3-day history of fever, nausea, vomiting, and a rash." | 1.30 | Azathioprine hypersensitivity reaction in a patient with ulcerative colitis. ( Garey, KW; Rainish, MC; Streetman, DS, 1998) |
| " Medical files were reviewed for adverse side effects: fever, pancreatitis, infections, gastrointestinal intolerance, aminotransferase level increase, leukopenia, and thrombocytopenia." | 1.30 | Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. ( Kirschner, BS, 1998) |
| "Thus, differential diagnosis of Goodpasture's syndrome (and probably of any "pulmonary renal syndrome") should include azathioprine hypersensitivity." | 1.29 | Azathioprine hypersensitivity mimicking Goodpasture's syndrome. ( Krapf, R; Schmidl, M; Stetter, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (27.64) | 18.7374 |
| 1990's | 28 (22.76) | 18.2507 |
| 2000's | 25 (20.33) | 29.6817 |
| 2010's | 32 (26.02) | 24.3611 |
| 2020's | 4 (3.25) | 2.80 |
| Authors | Studies |
|---|---|
| Salehi, T | 1 |
| Fleet, AP | 1 |
| Hissaria, P | 1 |
| Carroll, RP | 1 |
| Au Peh, C | 1 |
| Marinaki, AM | 1 |
| Arenas-Hernandez, M | 1 |
| Zarca, K | 2 |
| Chansavang, A | 1 |
| Loriot, MA | 2 |
| Durand-Zaleski, I | 2 |
| Pallet, N | 2 |
| McKenzie, T | 1 |
| Dheda, S | 1 |
| Mantha, M | 1 |
| Larsen, C | 1 |
| Jensen, CH | 1 |
| Fanciullo, J | 1 |
| Sousa, M | 1 |
| Proença, L | 1 |
| Carvalho, J | 1 |
| Terziroli Beretta-Piccoli, B | 1 |
| Mieli-Vergani, G | 1 |
| Vergani, D | 1 |
| Hessels, AC | 1 |
| Sanders, JSF | 1 |
| van de Ven, AAJM | 1 |
| Kroesen, BJ | 1 |
| Lambeck, AJA | 1 |
| Rutgers, A | 1 |
| Stegeman, CA | 1 |
| Chatellier, G | 1 |
| James, A | 1 |
| Blagojevic, J | 1 |
| Benham, SW | 1 |
| Cornall, R | 1 |
| Frater, J | 1 |
| Lennard, L | 1 |
| Chen, D | 1 |
| Lian, F | 1 |
| Yuan, S | 1 |
| Wang, Y | 1 |
| Zhan, Z | 1 |
| Ye, Y | 1 |
| Qiu, Q | 1 |
| Xu, H | 1 |
| Liang, L | 1 |
| Yang, X | 1 |
| García-Martín, P | 1 |
| Sánchez-Pérez, J | 1 |
| Fraga, J | 1 |
| García-Diez, A | 1 |
| Yang, S | 1 |
| McHargue, C | 1 |
| Kessler, C | 1 |
| Tschumi, S | 1 |
| Simonetti, GD | 1 |
| Bianchetti, MG | 1 |
| Kim, HY | 1 |
| Kim, JW | 1 |
| Kim, MJ | 2 |
| Lee, YM | 1 |
| Kang, B | 1 |
| Choe, YH | 2 |
| Lee, SY | 1 |
| Schmutz, JL | 1 |
| Roberts, RL | 2 |
| Barclay, ML | 2 |
| Lee, IH | 1 |
| Kang, GW | 1 |
| Kim, KC | 1 |
| Ardalan, ZS | 1 |
| Vasudevan, A | 1 |
| Testro, AG | 1 |
| Cheraghi, N | 1 |
| Yasuda, M | 1 |
| Deng, A | 1 |
| Mailhot, J | 1 |
| Anthony, D | 1 |
| Diethelm, M | 1 |
| Brändle, M | 1 |
| van Moorsel, SA | 1 |
| Bevers, N | 1 |
| Meurs, M | 1 |
| van Rossum, LK | 1 |
| Hooymans, PM | 1 |
| Wong, DR | 1 |
| Nagy, F | 1 |
| Molnar, T | 1 |
| Szepes, Z | 1 |
| Farkas, K | 1 |
| Nyari, T | 1 |
| Lonovics, J | 1 |
| Karaarslan, IK | 1 |
| Turkmen, M | 1 |
| Ozturk, G | 1 |
| Unal, I | 1 |
| Ertam, I | 1 |
| Kazandi, AC | 1 |
| El-Azhary, RA | 1 |
| Brunner, KL | 1 |
| Gibson, LE | 1 |
| Hindorf, U | 1 |
| Johansson, M | 1 |
| Eriksson, A | 1 |
| Kvifors, E | 1 |
| Almer, SH | 1 |
| Pursnani, A | 1 |
| Yee, H | 1 |
| Slater, W | 1 |
| Sarswat, N | 1 |
| Makhzoumi, Z | 1 |
| DeCapite, T | 1 |
| Gaspari, A | 1 |
| Wahed, M | 1 |
| Louis-Auguste, JR | 1 |
| Baxter, LM | 1 |
| Limdi, JK | 1 |
| McCartney, SA | 1 |
| Lindsay, JO | 1 |
| Bloom, SL | 1 |
| Valdivieso, R | 1 |
| Cevallos, F | 1 |
| Caballero, MT | 1 |
| Quirce, S | 1 |
| Andrejic, J | 1 |
| Rojas-Balcazar, J | 1 |
| Dennis, M | 1 |
| Berkelhammer, C | 1 |
| Korelitz, BI | 1 |
| Reddy, B | 1 |
| Bratcher, J | 1 |
| Lehmann, P | 1 |
| Fleck, M | 1 |
| Schoelmerich, J | 1 |
| Haerle, P | 1 |
| Landy, J | 1 |
| Bhuva, N | 1 |
| Marinaki, A | 1 |
| Mawdsley, J | 1 |
| Mayo, MJ | 1 |
| Bidinger, JJ | 1 |
| Sky, K | 1 |
| Battafarano, DF | 1 |
| Henning, JS | 1 |
| Dewit, O | 1 |
| Moreels, T | 1 |
| Baert, F | 1 |
| Peeters, H | 1 |
| Reenaers, C | 1 |
| de Vos, M | 1 |
| Van Hootegem, P | 1 |
| Muls, V | 1 |
| Veereman, G | 1 |
| Mana, F | 1 |
| Van Outryve, M | 1 |
| Holvoet, J | 1 |
| Naegels, S | 1 |
| Piessevaux, H | 1 |
| Horsmans, Y | 1 |
| Gala, JL | 1 |
| Meggitt, SJ | 1 |
| Anstey, AV | 1 |
| Mohd Mustapa, MF | 1 |
| Reynolds, NJ | 1 |
| Wakelin, S | 1 |
| Jang, KT | 1 |
| Turow, A | 1 |
| Yong, TY | 1 |
| Fok, JS | 1 |
| Li, JY | 1 |
| Hinrichs, R | 1 |
| Schneider, LA | 1 |
| Ozdemir, C | 1 |
| Staib, G | 1 |
| Scharffetter- Kochanek, K | 1 |
| Dubinsky, MC | 1 |
| Feldman, EJ | 1 |
| Abreu, MT | 1 |
| Targan, SR | 1 |
| Vasiliauskas, EA | 1 |
| Mahadevan, U | 1 |
| Mayo, JM | 1 |
| Colmenarejo, MB | 1 |
| Vaquerizo, PJ | 1 |
| Gutierrez, MV | 1 |
| Bajaj, JS | 1 |
| Saeian, K | 1 |
| Varma, RR | 1 |
| Franco, J | 1 |
| Knox, JF | 1 |
| Podoll, J | 1 |
| Emmons, J | 1 |
| Levy, M | 1 |
| Binion, DG | 1 |
| Bir, K | 1 |
| Herzenberg, AM | 1 |
| Carette, S | 1 |
| Karhadkar, AS | 1 |
| Schwartz, HJ | 1 |
| Arora, M | 1 |
| Dutta, SK | 1 |
| Kolho, KL | 1 |
| Ruuska, T | 1 |
| Savilahti, E | 1 |
| Ooi, CY | 1 |
| Bohane, TD | 1 |
| Lee, D | 1 |
| Naidoo, D | 1 |
| Day, AS | 1 |
| de Fonclare, AL | 1 |
| Khosrotehrani, K | 1 |
| Aractingi, S | 1 |
| Duriez, P | 1 |
| Cosnes, J | 1 |
| Beaugerie, L | 1 |
| Lees, CW | 1 |
| Maan, AK | 1 |
| Hansoti, B | 1 |
| Satsangi, J | 1 |
| Arnott, ID | 1 |
| Kirsner, JB | 1 |
| Deutsch, S | 1 |
| Hanauer, SB | 1 |
| Mosbech, H | 1 |
| Andersen, CW | 1 |
| Lawson, DH | 1 |
| Lovatt, GE | 1 |
| Gurton, CS | 1 |
| Hennings, RC | 1 |
| Watts, GF | 1 |
| Corston, R | 1 |
| Riabchinskaia, LA | 1 |
| Lazareva, DN | 1 |
| Wańkowicz, Z | 1 |
| Kałczak, M | 1 |
| Panasiuk, E | 1 |
| Ciszkiewicz, Z | 1 |
| Davis, M | 1 |
| Eddleston, AL | 2 |
| Williams, R | 2 |
| Bommelaer, G | 2 |
| Lapuelle, J | 1 |
| Rumeau, JL | 1 |
| Ribet, A | 1 |
| Pillans, PI | 1 |
| Tooke, AF | 1 |
| Bateman, ED | 1 |
| Ainslie, GM | 1 |
| Stetter, M | 1 |
| Schmidl, M | 1 |
| Krapf, R | 1 |
| Wilson, BE | 1 |
| Parsonnet, J | 1 |
| Paterson, AJ | 1 |
| Lamey, PJ | 1 |
| Lewis, MA | 1 |
| Nolan, A | 1 |
| Rademaker, M | 1 |
| Knowles, SR | 1 |
| Gupta, AK | 1 |
| Shear, NH | 2 |
| Sauder, D | 1 |
| Smak Gregoor, PJ | 1 |
| van Saase, JL | 1 |
| Weimar, W | 1 |
| Kramer, P | 1 |
| Plumb, R | 1 |
| Doolittle, GC | 1 |
| Parnham, AP | 1 |
| Dittmer, I | 1 |
| Mathieson, PW | 1 |
| McIver, A | 1 |
| Dudley, C | 1 |
| Compton, MR | 1 |
| Crosby, DL | 1 |
| Aissaoui, M | 1 |
| Mounedji, N | 1 |
| Mathelier-Fusade, P | 1 |
| Leynadier, F | 1 |
| Dubost, JJ | 1 |
| Abergel, A | 1 |
| Soubrier, M | 1 |
| Sauvezie, B | 1 |
| Tumani, H | 1 |
| George, A | 1 |
| Nau, R | 1 |
| Caramaschi, P | 1 |
| Biasi, D | 1 |
| Carletto, A | 1 |
| Bambara, LM | 1 |
| Knowles, S | 1 |
| Garey, KW | 1 |
| Streetman, DS | 1 |
| Rainish, MC | 1 |
| Fields, CL | 1 |
| Robinson, JW | 1 |
| Roy, TM | 1 |
| Ossorio, MA | 1 |
| Byrd, RP | 1 |
| Marion, JF | 1 |
| Tanis, AA | 1 |
| Kirschner, BS | 1 |
| Romagnuolo, J | 1 |
| Sadowski, DC | 1 |
| Lalor, E | 1 |
| Jewell, L | 1 |
| Thomson, AB | 1 |
| Stratton, JD | 1 |
| Farrington, K | 1 |
| Sanada, I | 1 |
| Kawano, F | 1 |
| Tsukamoto, A | 1 |
| Kiyokawa, T | 1 |
| Lauerma, AI | 1 |
| Koivuluhta, M | 1 |
| Alenius, H | 1 |
| Sofat, N | 1 |
| Houghton, J | 1 |
| McHale, J | 1 |
| Higgens, CS | 1 |
| Craner, MJ | 1 |
| Zajicek, JP | 1 |
| Corbett, M | 1 |
| Schlup, M | 1 |
| Miserocchi, E | 1 |
| Baltatzis, S | 1 |
| Roque, MR | 1 |
| Ahmed, AR | 1 |
| Foster, CS | 1 |
| Haas, J | 1 |
| Patzold, U | 1 |
| Stamm, T | 1 |
| Brandt, LJ | 1 |
| Decker, JL | 1 |
| Klippel, JH | 1 |
| Plotz, PH | 1 |
| Steinberg, AD | 1 |
| Goldenberg, DL | 1 |
| Stor, RA | 1 |
| Doré, P | 1 |
| Meurice, JC | 1 |
| Recart, D | 1 |
| Patte, F | 1 |
| Meys, E | 1 |
| Devogelaer, JP | 1 |
| Geubel, A | 1 |
| Rahier, J | 1 |
| Nagant de Deuxchaisnes, C | 1 |
| Jeurissen, ME | 1 |
| Boerbooms, AM | 1 |
| van de Putte, LB | 1 |
| Kruijsen, MW | 1 |
| Collison, DW | 1 |
| Dahlberg, PJ | 1 |
| Hogan, JD | 1 |
| Vande Walle, JG | 1 |
| Donckerwolcke, RA | 1 |
| Riedel, RR | 1 |
| Schmitt, A | 1 |
| de Jonge, JP | 1 |
| Hartmann, A | 1 |
| Vandepitte, K | 1 |
| Vanrenterghem, Y | 1 |
| Michielsen, P | 1 |
| Saway, PA | 1 |
| Heck, LW | 1 |
| Bonner, JR | 1 |
| Kirklin, JK | 1 |
| Cooper, C | 1 |
| Cotton, DW | 1 |
| Minihane, N | 1 |
| Cawley, MI | 1 |
| Bosch, FH | 1 |
| Meinders, AE | 1 |
| Rhodes, J | 1 |
| Bainton, D | 1 |
| Beck, P | 1 |
| Campbell, H | 1 |
| Wildhirt, E | 1 |
| Burton, JL | 2 |
| Greaves, MW | 2 |
| Marks, J | 1 |
| Dawber, RP | 1 |
| King, JO | 1 |
| Laver, MC | 1 |
| Fairley, KF | 1 |
| Ames, GA | 1 |
| Cooper, MR | 1 |
| Hansen, KS | 1 |
| Maynard, CD | 1 |
| Elrod, IW | 1 |
| Spurr, CL | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| McCullough, DL | 1 |
| Gittes, RF | 1 |
| Lechner, K | 1 |
| Lyons, H | 1 |
| Pinn, VW | 1 |
| Cortell, S | 1 |
| Cohen, JJ | 1 |
| Harrington, JT | 1 |
| Cameron, JS | 1 |
| Lie, TS | 1 |
| Smith, MG | 1 |
| Golding, PL | 1 |
| Mitchell, CG | 1 |
| Kemp, A | 1 |
| Richards, AJ | 1 |
| Swinson, DR | 1 |
| Hamilton, EB | 1 |
| Hillman, HS | 1 |
| Sloth, K | 1 |
| Thomsen, AC | 1 |
| Japa, J | 1 |
| Kardaszewicz, E | 1 |
| Makulu, DR | 1 |
| Wright, P | 1 |
| Barth, P | 1 |
| Kommerell, B | 1 |
| Schiemer, HG | 1 |
| Schimpf, K | 1 |
| Schlierf, G | 1 |
| Wegener, K | 1 |
| Asadov, C | 1 |
| Aliyeva, G | 1 |
| Mustafayeva, K | 1 |
| Grassia, R | 1 |
| Paolo Coppeta, G | 1 |
| Staiano, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenomic Analysis of 6-mercaptopurine in Pediatric Acute Lymphoblastic Leukemia[NCT04770922] | 80 participants (Actual) | Observational | 2021-02-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for azathioprine and Allergy, Drug
| Article | Year |
|---|---|
Reducing risk in thiopurine therapy.
Topics: Azathioprine; Drug Hypersensitivity; Erythrocytes; Female; Genotype; Humans; Male; Mercaptopurine; M | 2020 |
Autoimmune hepatitis: Standard treatment and systematic review of alternative treatments.
Topics: Adult; Age Factors; Azathioprine; Child; Complementary Therapies; Drug Hypersensitivity; Glucocortic | 2017 |
Update on thiopurine pharmacogenetics in inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Drug-Related Side Effects a | 2015 |
Management of autoimmune hepatitis.
Topics: Azathioprine; Budesonide; Drug Hypersensitivity; Hepatitis, Autoimmune; Humans; Immunosuppressive Ag | 2011 |
The cutaneous and systemic manifestations of azathioprine hypersensitivity syndrome.
Topics: Adult; Aged; Azathioprine; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Sch | 2011 |
Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease.
Topics: Antibodies, Monoclonal; Azathioprine; Biotransformation; Crohn Disease; Drug Hypersensitivity; Drug | 2012 |
Adverse effects of azathioprine.
Topics: Alopecia; Azathioprine; Bone Marrow Diseases; Carcinogens; Drug Hypersensitivity; Drug Interactions; | 1984 |
Acute polyarthritis associated with azathioprine for interstitial lung disease.
Topics: Acute Disease; Arthritis; Azathioprine; Drug Hypersensitivity; Drug Therapy, Combination; Female; Hu | 1995 |
Azathioprine hypersensitivity-like reactions--a case report and a review of the literature.
Topics: Adolescent; Azathioprine; Critical Care; Drug Hypersensitivity; Female; Humans; Immunosuppressive Ag | 1995 |
Hypersensitivity reaction to azathioprine.
Topics: Acute Kidney Injury; Adult; Anaphylaxis; Arthritis, Psoriatic; Azathioprine; Diagnosis, Differential | 1998 |
Azathioprine in inflammatory bowel disease, a safe alternative?
Topics: Azathioprine; Bone Marrow; Drug Hypersensitivity; Female; Fertility; Humans; Immunosuppressive Agent | 1998 |
Cholestatic hepatocellular injury with azathioprine: a case report and review of the mechanisms of hepatotoxicity.
Topics: Azathioprine; Cholestasis, Intrahepatic; Crohn Disease; Drug Hypersensitivity; Humans; Immunosuppres | 1998 |
Azathioprine hypersensitivity. Case report and review of the literature.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Graft Rejection; Heart Transplantation; Humans; Male | 1988 |
Acquired inhibitors in nonhemophilic patients.
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Pro | 1974 |
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath | 1971 |
Thiopurine S-Methyltransferase as a Pharmacogenetic Biomarker: Significance of Testing and Review of Major Methods.
Topics: Animals; Drug Hypersensitivity; Gene Frequency; Genotyping Techniques; Humans; Mercaptopurine; Methy | 2017 |
3 trials available for azathioprine and Allergy, Drug
| Article | Year |
|---|---|
Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months.
Topics: Adolescent; Adult; Amenorrhea; Azathioprine; Child; Clinical Trials as Topic; Complement C3; Cycloph | 1975 |
Controlled trial of azathioprine in Crohn's disease.
Topics: Adolescent; Adult; Aged; Arthritis; Azathioprine; Clinical Trials as Topic; Crohn Disease; Double-Bl | 1971 |
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
104 other studies available for azathioprine and Allergy, Drug
| Article | Year |
|---|---|
Human leukocyte antigen association with azathioprine-induced drug hypersensitivity reactions in patients with anti-neutrophil cytoplasmic antibody associated vasculitis.
Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic; | 2023 |
Cost-effectiveness analysis of pretreatment screening for NUDT15 defective alleles.
Topics: Asian People; Azathioprine; Bone Marrow Diseases; Cost-Benefit Analysis; Decision Trees; Drug Hypers | 2020 |
Azathioprine hypersensitivity syndrome: report of two cases.
Topics: Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Drug Hypersensitivity S | 2021 |
Point-Counterpoint: TPMT Genotyping for Azathioprine in Adult Medicine.
Topics: Azathioprine; Drug Hypersensitivity; Genotype; Humans; Immunosuppressive Agents; Methyltransferases; | 2017 |
Hypersensitivity to azathioprine in a patient with Crohn's disease: a case report.
Topics: Azathioprine; Crohn Disease; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Middle | 2017 |
Azathioprine Hypersensitivity Syndrome in a Cohort of Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Patients.
Topics: Adult; Aged; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antirheumatic Agents; Azath | 2019 |
Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis.
Topics: Antimetabolites; Azathioprine; Cost-Benefit Analysis; Drug Hypersensitivity; Genetic Testing; Geneti | 2019 |
Azathioprine hypersensitivity presenting as septic shock with encephalopathy.
Topics: Aged; Azathioprine; Brain Diseases; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; S | 2013 |
Implementation of TPMT testing.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Cost-Benefit Analysis; Drug Hypersensitivity; Drug La | 2014 |
Association of thiopurine methyltransferase status with azathioprine side effects in Chinese patients with systemic lupus erythematosus.
Topics: Adult; Alleles; Alopecia; Asian People; Azathioprine; Chemical and Drug Induced Liver Injury; Cohort | 2014 |
Neutrophilic eccrine hidradenitis in a patient with Crohn's disease and azathioprine hypersensitivity syndrome.
Topics: Aged; Azathioprine; Crohn Disease; Drug Hypersensitivity; Hidradenitis; Humans; Immunosuppressive Ag | 2014 |
An asymptomatic papulopustular eruption in an immunosuppressed patient.
Topics: Azathioprine; Drug Eruptions; Drug Hypersensitivity; Female; Hepatitis, Autoimmune; Humans; Immunoco | 2014 |
New-onset bone marrow aplasia in a 15-year-old adolescent with pauci-immune crescentic glomerulonephritis: Questions.
Topics: Adolescent; Azathioprine; Bone Marrow; Drug Hypersensitivity; Glomerulonephritis; Humans; Immunosupp | 2015 |
Safe azathioprine treatment in a pediatric ulcerative colitis patient with TPMT*16 by thiopurine metabolite monitoring.
Topics: Adolescent; Azathioprine; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Methyltransferas | 2014 |
[Neutrophilic eccrine hidradenitis and azathioprine hypersensitivity syndrome].
Topics: Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Hypersensitivity; Hidradenitis; Humans; I | 2014 |
Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Bronchoscopy; Drug Hypersensitivity; Gr | 2016 |
Arthralgia and Fevers in a Patient With Autoimmune Hepatitis.
Topics: Aged; Arthralgia; Azathioprine; Drug Hypersensitivity; Erythema Nodosum; Exanthema; Fever; Hepatitis | 2016 |
Azathioprine hypersensitivity presenting as neutrophilic dermatosis and erythema nodosum.
Topics: Azathioprine; Crohn Disease; Drug Hypersensitivity; Erythema Nodosum; Humans; Immunosuppressive Agen | 2016 |
[Not Available].
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Drug Ther | 2016 |
Azathioprine Therapy in a Pediatric TPMT-Deficient Patient-Still an Option.
Topics: Adolescent; Azathioprine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Monitoring; | 2017 |
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hyperse | 2008 |
A case of drug hypersensitivity due to azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male | 2009 |
Sweet syndrome as a manifestation of azathioprine hypersensitivity.
Topics: Adult; Aged; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immuno | 2008 |
Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease.
Topics: Adult; Azathioprine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Immuno | 2009 |
Hypersensitivity myocarditis associated with azithromycin exposure.
Topics: Anti-Bacterial Agents; Azathioprine; Azithromycin; Drug Hypersensitivity; Drug Therapy, Combination; | 2009 |
Development of Beau's lines in two patients receiving azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Male; Middle Ag | 2009 |
Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Drug Hypersensitivity; Drug Resistance; Fe | 2009 |
Chronic urticaria caused by folic acid.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Drug Hypersensitivity; Female; Folic Acid; Humans | 2009 |
Azathioprine-induced hypersensitivity hepatitis: tolerance to 6-mercaptopurine.
Topics: Acute Disease; Azathioprine; Chemical and Drug Induced Liver Injury; Colitis, Ulcerative; Drug Hyper | 2010 |
Desensitization of patients with allergic reactions to immunosuppressives in the treatment of inflammatory bowel disease.
Topics: Azathioprine; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Immunosuppressive Agents; | 2010 |
Azathioprine-associated hypersensitivity reaction in a patient with Churg Strauss vasculitis.
Topics: Azathioprine; Churg-Strauss Syndrome; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; | 2010 |
Novel thiopurine methyltransferase variant TPMT*28 results in a misdiagnosis of TPMT deficiency.
Topics: Amino Acid Substitution; Azathioprine; Colitis, Ulcerative; Diagnostic Errors; Drug Hypersensitivity | 2011 |
Limitations of extensive TPMT genotyping in the management of azathioprine-induced myelosuppression in IBD patients.
Topics: Adolescent; Adult; Aged; Azathioprine; DNA Mutational Analysis; Drug Hypersensitivity; Female; Genot | 2011 |
British Association of Dermatologists' guidelines for the safe and effective prescribing of azathioprine 2011.
Topics: Abnormalities, Drug-Induced; Adult; Aged; Azathioprine; Bone Marrow Diseases; Chemical and Drug Indu | 2011 |
Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis.
Topics: Azathioprine; Child; Colitis, Ulcerative; Drug Hypersensitivity; Female; Humans; Immunosuppressive A | 2011 |
Azathioprine hypersensitivity presenting as cardiogenic shock and Sweet's syndrome in a patient with microscopic polyangiitis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Female; Humans; I | 2012 |
Azathioprine hypersensitivity in a patient with peripheral demyelinating polyneuropathy.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Methyltransfera | 2003 |
Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Inflammatory B | 2003 |
6TG: when less is more than you bargained for.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; | 2003 |
Hypersensitivity reaction to azathioprine in a patient with ulcerative colitis. Infrequent manifestations.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Diagnosis, Differential; Drug Hypersensitivity; Fever; Hum | 2004 |
Increased rates of early adverse reaction to azathioprine in patients with Crohn's disease compared to autoimmune hepatitis: a tertiary referral center experience.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Arthralgia; Azathioprine; Crohn Disease; Disease Sus | 2005 |
Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis.
Topics: Acute Disease; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Female; Granulomatosis | 2006 |
Severe muscular weakness: an unusual adverse effect of azathioprine therapy.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immunosuppre | 2006 |
Severe adverse reactions to Infliximab therapy are common in young children with inflammatory bowel disease.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Child; Ch | 2007 |
Thiopurine metabolite monitoring in paediatric inflammatory bowel disease.
Topics: Adolescent; Azathioprine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Hype | 2007 |
Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Erythema Nodo | 2007 |
Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease.
Topics: Adult; Age Distribution; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Administration Sched | 2008 |
Selected individual therapeutic problems in inflammatory bowel disease.
Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ | 1984 |
[Azathioprine induced hypersensitivity].
Topics: Adult; Aged; Azathioprine; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Male | 1982 |
Hypersensitivity to azathioprine in myasthenia gravis.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Mercaptopurine; Middle Aged; Myasthenia Gravis | 1984 |
[Effect of prodigiozan, levamisole and methyluracil on delayed hypersensitivity against a background of immunosuppressor use].
Topics: Animals; Azathioprine; Cyclophosphamide; Drug Hypersensitivity; Drug Interactions; Female; Hypersens | 1983 |
[Acute drug-induced renal failure with severe clinical course].
Topics: Acute Kidney Injury; Adolescent; Anti-Infective Agents; Anticoagulants; Azathioprine; Diuretics; Dru | 1982 |
Hypersensitivity and jaundice due to azathioprine.
Topics: Azathioprine; Cholestasis; Drug Hypersensitivity; Female; Hepatitis; Humans; Middle Aged | 1980 |
[Hypersensitivity reactions and cholestasis. Possible effect of azathioprine].
Topics: Azathioprine; Cholestasis; Drug Hypersensitivity; Female; Humans; Middle Aged | 1980 |
Azathioprine hypersensitivity mimicking Goodpasture's syndrome.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Diagnosis, Differential; Drug Hypers | 1994 |
Azathioprine hypersensitivity mimicking sepsis in a patient with Crohn's disease.
Topics: Aged; Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Hypersensitivity; Fever; Humans; In | 1993 |
Pemphigus vulgaris precipitated by glibenclamide therapy.
Topics: Aged; Azathioprine; Candidiasis, Oral; Diabetes Mellitus, Type 2; Drug Hypersensitivity; Fluconazole | 1993 |
Fever and rigors as sole symptoms of azathioprine hypersensitivity.
Topics: Azathioprine; Drug Hypersensitivity; Fever; Humans; Immunosuppressive Agents; Kidney Transplantation | 1995 |
Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Thera | 1996 |
Acute allergic reactions associated with azathioprine.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Nephritis, Interstitia | 1996 |
Rhabdomyolysis associated with azathioprine hypersensitivity syndrome.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Male; Rhabdomyolysis | 1996 |
[Pancreatitis caused by azathioprine: immuno-allergy?].
Topics: Acute Disease; Adult; Azathioprine; Crohn Disease; Drug Hypersensitivity; Humans; Male; Pancreatitis | 1996 |
[Acute cytolytic hepatitis in azathioprine hypersensitivity].
Topics: Acute Disease; Adult; Antirheumatic Agents; Azathioprine; Behcet Syndrome; Chemical and Drug Induced | 1996 |
[Myasthenic crisis caused by azathioprine-induced fever].
Topics: Aged; Azathioprine; Critical Care; Drug Hypersensitivity; Drug Therapy, Combination; Fever; Humans; | 1997 |
Azathioprine hypersensitivity in a patient affected by systemic lupus erythematosus.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Lupus Erythema | 1997 |
Azathioprine hypersensitivity reactions: caution upon rechallenge.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Retreatment | 1997 |
Azathioprine hypersensitivity reaction in a patient with ulcerative colitis.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Immunosuppressive Agents; M | 1998 |
Toxicity of 6-mercaptopurine/azathioprine in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow; Child; Colorectal Neoplasms; Drug Hypersensitivity; Fe | 1998 |
Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Databases as Topic; Drug Hypersensitivity; | 1998 |
Relapse of vasculitis, sepsis, or azathioprine allergy?
Topics: Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agents; Male; Re | 1998 |
[Autoimmune hepatitis complicated by intolerable pain of lower extremities and shock due to azathioprine].
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Hepatitis, Autoimmune; Humans; Immunosuppressive | 2000 |
Recalcitrant allergic contact dermatitis from azathioprine tablets.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Dermatitis, Allergic Contact; Drug Hypersensitivity; | 2001 |
Azathioprine hypersensitivity.
Topics: Adult; Antirheumatic Agents; Azathioprine; Drug Hypersensitivity; Drug Therapy, Combination; Female; | 2001 |
Immunosuppressive treatments in MS--side effects from azathioprine.
Topics: Azathioprine; Drug Hypersensitivity; Humans; Immunosuppressive Agents; Multiple Sclerosis; Nausea; P | 2001 |
Azathioprine hypersensitivity mimicking underlying inflammatory bowel disease.
Topics: Adult; Azathioprine; Colitis, Ulcerative; Crohn Disease; Diagnosis, Differential; Drug Hypersensitiv | 2001 |
The effect of treatment and its related side effects in patients with severe ocular cicatricial pemphigoid.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Azathi | 2002 |
[Intrahepatic cholestasis, an allergic reaction in azathioprine therapy?].
Topics: Adult; Azathioprine; Cholestasis; Drug Hypersensitivity; Humans; Male; Multiple Sclerosis | 1978 |
Formication and azathioprine therapy.
Topics: Ants; Azathioprine; Drug Hypersensitivity; Female; Humans; Middle Aged; Nervous System Diseases; Sen | 1977 |
Azathioprine hypersensitivity mimicking an acute exacerbation of dermatomyositis.
Topics: Acute Disease; Azathioprine; Dermatomyositis; Diagnosis, Differential; Drug Hypersensitivity; Female | 1975 |
[Reaction of hypersensitivity to azathioprine].
Topics: Azathioprine; Drug Hypersensitivity; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1992 |
Fever, hepatitis and acute interstitial nephritis in a patient with rheumatoid arthritis. Concurrent manifestations of azathioprine hypersensitivity.
Topics: Acute Disease; Arthritis, Rheumatoid; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; | 1992 |
Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Eruptions; D | 1990 |
Azathioprine hypersensitivity in bullous pemphigoid.
Topics: Aged; Azathioprine; Drug Hypersensitivity; Female; Fever; Headache; Humans; Pemphigoid, Bullous; Ski | 1990 |
Association of fever, nasal congestion and rise in serum creatinine with azathioprine therapy.
Topics: Azathioprine; Child; Creatinine; Drug Hypersensitivity; Female; Fever; Humans; Kidney Transplantatio | 1990 |
Gastrointestinal type 1 hypersensitivity to azathioprine.
Topics: Azathioprine; Drug Hypersensitivity; Edema; Eosinophilia; Gastroenteritis; Humans; Intestinal Mucosa | 1990 |
Azathioprine hypersensitivity in a renal transplant recipient.
Topics: Adult; Azathioprine; Drug Hypersensitivity; Fever; Humans; Kidney Transplantation; Male | 1990 |
Azathioprine hypersensitivity manifesting as acute focal hepatocellular necrosis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; | 1986 |
[General malaise, high fever and arthralgia as a rare side effect of azathioprine].
Topics: Azathioprine; Drug Hypersensitivity; Fever; Glomerulonephritis; Humans; Joint Diseases; Male; Middle | 1985 |
[Penicillamine therapy of chronic liver diseases].
Topics: Azathioprine; Chronic Disease; Drug Hypersensitivity; Female; Glucocorticoids; Hepatitis; Humans; Li | 1974 |
Azathioprine in pemphigus vulgaris.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Male; | 1970 |
Sensitivity to azathioprine.
Topics: Azathioprine; Diagnosis, Differential; Drug Hypersensitivity; Female; Glomerulonephritis; Graft Reje | 1972 |
Platelet survival and sequestration patterns in thrombocytopenic disorders.
Topics: Adult; Aged; Azathioprine; Blood Platelets; Cell Survival; Chloramphenicol; Chromium Isotopes; Dexam | 1972 |
Successful renal transplantation after forty-five hours of extracorporeal perfusion.
Topics: Acute Kidney Injury; Azathioprine; Biopsy; Cadaver; Cold Temperature; Drug Hypersensitivity; Graft R | 1973 |
Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.
Topics: Acute Kidney Injury; Adult; Azathioprine; Chlorothiazide; Drug Hypersensitivity; Eosinophils; Female | 1973 |
Azathioprine for pemphigus and pemphigoid--a 4 year follow-up.
Topics: Adult; Aged; Anemia; Azathioprine; Bone Neoplasms; Drug Evaluation; Drug Hypersensitivity; Female; F | 1974 |
[Immunosuppressive therapy in experimental and clinical liver transplantation].
Topics: Anaphylaxis; Animals; Anti-Bacterial Agents; Antilymphocyte Serum; Azathioprine; Depression, Chemica | 1970 |
Cell-mediated immune responses in chronic liver diseases.
Topics: Acidosis, Renal Tubular; Antigens; Autoimmune Diseases; Azathioprine; Cell Migration Inhibition; Chr | 1972 |
Azathioprine in connective tissue disorders.
Topics: Anemia; Arthritis, Rheumatoid; Azathioprine; Drug Hypersensitivity; Gold; Humans; Male; Middle Aged | 1972 |
Intestinal malabsorption with subtotal villous atrophy unresponsive to a gluten-free diet but responding to immunosuppressive therapy.
Topics: Adult; Atrophy; Azathioprine; Biopsy; Diet Therapy; Drug Hypersensitivity; Glutens; Humans; Intestin | 1972 |
Acute renal insufficiency during treatment with azathioprine.
Topics: Acute Kidney Injury; Administration, Oral; Azathioprine; Biopsy; Drug Hypersensitivity; Glomerular F | 1971 |
[Results of immunosuppressive treatment of visceral lupus erythematosus].
Topics: Adolescent; Adult; Aged; Azathioprine; Drug Hypersensitivity; Female; Humans; Immunosuppressive Agen | 1969 |
Immune response to insulin in guinea pigs.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Azathioprine; Body Weight; Cattle; Chromatograp | 1971 |
[Purpura fulminans in the pathological anatomical picture of a case of thrombophlebitis migrans et saltans].
Topics: Adult; Azathioprine; Drug Hypersensitivity; Female; Heparin; Humans; Prednisone; Purpura; Thrombophl | 1968 |
Severe muscular weakness as an isolated symptom of azathioprine hypersensitivity.
Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Drug Hypersensitivity; Humans; Male; Mercaptopurine; | 2011 |