azathioprine has been researched along with Allergic Encephalomyelitis in 10 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The author presents evidence from published papers of research done by numerous investigators that Multiple Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid." | 7.67 | Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988) |
| "The author presents evidence from published papers of research done by numerous investigators that Multiple Sclerosis (MS) is an autoimmune disease, that the target tissue is the myelin sheath which covers the nerve fibers in the brain and spinal cord, that Myelin Basic Protein (MBP) is the antigen or one of the antigens involved, that the autoimmune reaction is effected by sensitized lymphocytes together with a specific antibody, that Experimental Allergic Encephalomyelitis (EAE) produced in animals can be used as a model for MS, and that the autoimmune reaction in MS can possibly be suppressed by the use of MBP given by an intravenous procedure together with an immunosuppressive drug and a corticosteroid." | 3.67 | Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid. ( Eidinoff, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Field, EJ | 1 |
| Mertin, J | 1 |
| Cazzullo, CL | 1 |
| Blaszczyk, B | 1 |
| Karakoz, I | 1 |
| Gieldanowski, J | 1 |
| Eidinoff, H | 1 |
| Babington, RG | 1 |
| Wedeking, PW | 1 |
| Aarli, JA | 1 |
| Rosenthale, ME | 2 |
| Datko, LJ | 1 |
| Kassarich, J | 1 |
| Schneider, F | 1 |
| Vogel, CL | 1 |
| De Vita, VT | 1 |
| Lisak, RP | 1 |
| Kies, MW | 1 |
| Gluckman, MI | 1 |
2 reviews available for azathioprine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
[Immunosuppressive treatment im multiple sclerosis].
Topics: Adrenocorticotropic Hormone; Antilymphocyte Serum; Azathioprine; Cyclophosphamide; Encephalomyelitis | 1980 |
[Immunosuppressive treatment in neurological disorders].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Antilymphocyte Serum; Azathioprine; C | 1973 |
8 other studies available for azathioprine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Effect of imuran (azathioprine) on susceptibility of guinea pigs to allergic encephalomyelitis.
Topics: Animals; Azathioprine; Cyclophosphamide; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea | 1967 |
From etiology and pathogenesis to therapy of multiple sclerosis.
Topics: Animals; Azathioprine; Cortisone; Dexamethasone; Encephalomyelitis, Autoimmune, Experimental; Immuno | 1978 |
Effect of various immunosuppressive drugs on experimental allergic encephalomyelitis in chickens.
Topics: Animals; Antineoplastic Agents; Azathioprine; Chickens; Cyclophosphamide; Dactinomycin; Demecolcine; | 1977 |
Suppression of the immune reaction in multiple sclerosis might be achieved by intravenous injections of myelin basic protein, concomitant with the administration of an immunosuppressant and a corticosteroid.
Topics: Animals; Autoimmune Diseases; Azathioprine; Disease Models, Animal; Drug Therapy, Combination; Encep | 1988 |
The influence of cinanserin and selected pharmacologic agents on experimental allergic encephalomyelitis (EAE).
Topics: 5-Hydroxytryptophan; Amphetamine; Anilides; Animals; Azathioprine; Body Weight; Chlorpheniramine; Ci | 1971 |
Chemotherapy of experimental allergic encephalomyelitis (EAE).
Topics: Allopurinol; Aminocaproates; Analgesics; Animals; Antineoplastic Agents; Azathioprine; Body Weight; | 1969 |
Suppression of experimental allergic encephalomyelitis by NSC 82196, a new imidazole carboxamide derivative.
Topics: Amides; Animals; Azathioprine; Cyclophosphamide; Disease Models, Animal; Encephalomyelitis, Autoimmu | 1969 |
Immunopharmacologic activity of 1-aminocyclopentane-1-carboxylic acid.
Topics: Anaphylaxis; Animals; Azathioprine; Cortisone; Cyclopentanes; Cyclophosphamide; Encephalomyelitis, A | 1968 |