azathioprine has been researched along with Allergic Alveolitis, Extrinsic in 15 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 5.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| " According to the possibility of either idiopathic pulmonary fibrosis or chronic hypersensitivity pneumonitis, treatment included prednisolone, azathioprine, acetylcysteine and avoidance of contact with the parakeet, but there was an unfavorable response and the patient was subsequently referred for lung transplant." | 3.79 | Clinical case: Differential diagnosis of idiopathic pulmonary fibrosis. ( Alfaro, TM; Cordeiro, CR; Freitas, S, 2013) |
| "We present a case of drug-induced alveolitis following infliximab and azathioprine for the treatment of severe, generalised psoriasis and atopic eczema without pre-existing lung disease." | 3.74 | [Drug-induced alveolitis associated with infliximab/azathioprine therapy]. ( Dercken, HG; El-Hag, K; Hölzle, E; Prenzel, R, 2008) |
| "Chronic hypersensitivity pneumonitis (cHP) represents a severe lung disease often evolving to fibrosis with the subsequent destruction of the lung parenchyma." | 2.94 | An Open-label Study With Pirfenidone on Chronic Hypersensitivity Pneumonitis. ( Buendía-Roldan, I; Castillo-Castillo, K; Castillo-Pedroza, J; Estrada, A; Gaxiola, M; Mateos-Toledo, H; Mejía-Ávila, M; Mejía-Hurtado, JG; Rodríguez-Barreto, Ó; Rojas-Serrano, J; Selman, M, 2020) |
| "BAL lymphocytosis was associated with a favourable response to AZA treatment (OR 1." | 1.62 | Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine. ( Bastos, HN; Beltrão, M; Cruz-Martins, N; Cunha, R; Guimarães, S; Melo, N; Morais, A; Mota, PC; Moura, CS; Pereira, JM; Pimenta, AC; Raimundo, S; Rodrigues, MC; Sokhatska, O, 2021) |
| "Lung biopsies from patients with hypersensitivity pneumonitis (HP) have demonstrated small airway (SA) involvement, but there is no information concerning SA function in HP, and it is unknown whether pharmacological treatment could modify its function." | 1.46 | Small airway dysfunction in chronic hypersensitivity pneumonitis. ( Gochicoa-Rangel, L; Guerrero Zúñiga, S; Mateos Toledo, H; Mejía Ávila, M; Miguel Reyes, JL; Sánchez Hernández, J; Selman, M; Torre-Bouscoulet, L, 2017) |
| "The treatment of chronic hypersensitivity pneumonitis (cHP) often includes systemic oral corticosteroids, but the optimal pharmacologic management remains unclear." | 1.46 | Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis. ( Aravena, C; Collard, HR; Dubé, BP; Elicker, BM; Fell, CD; Johannson, KA; Jones, KD; Ley, B; Manganas, H; Morisset, J; Ryerson, CJ; Vittinghoff, E; Wolters, PJ, 2017) |
| "Azathioprine (AZA) is a purine analog that is commonly used for maintaining GPA remission after induction therapy with cyclophosphamide." | 1.43 | Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis. ( Kang, GW; Kim, KC; Lee, IH, 2016) |
| "A relapse of ulcerative colitis was treated with corticosteroids (CS) and IFX as rescue therapy." | 1.40 | [Severe interstitial lung disease due to treatment with infliximab and azathioprine]. ( Cecere, S; Hansen, LK; Thøgersen, T, 2014) |
| "Hypersensitivity pneumonitis was suspected." | 1.33 | Recurrent episodes of dermatomyositis-associated pneumonitis masquerading as hypersensitivity pneumonitis. ( Marik, PE; Vahid, B, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 6 (40.00) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fiddler, CA | 1 |
| Simler, N | 1 |
| Thillai, M | 1 |
| Parfrey, H | 1 |
| Mateos-Toledo, H | 1 |
| Mejía-Ávila, M | 1 |
| Rodríguez-Barreto, Ó | 1 |
| Mejía-Hurtado, JG | 1 |
| Rojas-Serrano, J | 1 |
| Estrada, A | 1 |
| Castillo-Pedroza, J | 1 |
| Castillo-Castillo, K | 1 |
| Gaxiola, M | 1 |
| Buendía-Roldan, I | 1 |
| Selman, M | 2 |
| Terras Alexandre, A | 1 |
| Martins, N | 1 |
| Raimundo, S | 2 |
| Melo, N | 2 |
| Catetano Mota, P | 1 |
| Novais E Bastos, H | 1 |
| Pereira, JM | 2 |
| Cunha, R | 2 |
| Guimarães, S | 2 |
| Souto Moura, C | 1 |
| Morais, A | 2 |
| Pimenta, AC | 1 |
| Cruz-Martins, N | 1 |
| Rodrigues, MC | 1 |
| Mota, PC | 1 |
| Sokhatska, O | 1 |
| Bastos, HN | 1 |
| Beltrão, M | 1 |
| Moura, CS | 1 |
| Guerrero Zúñiga, S | 1 |
| Sánchez Hernández, J | 1 |
| Mateos Toledo, H | 1 |
| Mejía Ávila, M | 1 |
| Gochicoa-Rangel, L | 1 |
| Miguel Reyes, JL | 1 |
| Torre-Bouscoulet, L | 1 |
| Cordeiro, CR | 1 |
| Alfaro, TM | 1 |
| Freitas, S | 1 |
| Hansen, LK | 1 |
| Cecere, S | 1 |
| Thøgersen, T | 1 |
| Lee, IH | 1 |
| Kang, GW | 1 |
| Kim, KC | 1 |
| Morisset, J | 1 |
| Johannson, KA | 1 |
| Vittinghoff, E | 1 |
| Aravena, C | 1 |
| Elicker, BM | 1 |
| Jones, KD | 1 |
| Fell, CD | 1 |
| Manganas, H | 1 |
| Dubé, BP | 1 |
| Wolters, PJ | 1 |
| Collard, HR | 1 |
| Ryerson, CJ | 1 |
| Ley, B | 1 |
| Vahid, B | 1 |
| Marik, PE | 1 |
| Churg, A | 1 |
| Müller, NL | 1 |
| Silva, CI | 1 |
| Wright, JL | 1 |
| El-Hag, K | 1 |
| Dercken, HG | 1 |
| Prenzel, R | 1 |
| Hölzle, E | 1 |
| Lanser, K | 1 |
| von Wichert, P | 1 |
| Cegla, UH | 1 |
| Liebetrau, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pirfenidone in the Chronic Hypersensitivity Pneumonitis Treatment[NCT02496182] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2015-07-31 | Recruiting | ||
| Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Randomized Controlled Trial[NCT05674994] | Phase 3 | 110 participants (Anticipated) | Interventional | 2023-10-26 | Recruiting | ||
| Cyclophosphamide Added to Corticosteroid in the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Placebo-controlled Randomized Trial[NCT02460588] | Phase 3 | 120 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Allergic Alveolitis, Extrinsic
| Article | Year |
|---|---|
[Therapeutic possibilities in alveolitis and pulmonary fibrosis].
Topics: Adrenal Cortex Hormones; Alveolitis, Extrinsic Allergic; Azathioprine; Humans; Penicillamine; Pulmon | 1990 |
2 trials available for azathioprine and Allergic Alveolitis, Extrinsic
| Article | Year |
|---|---|
An Open-label Study With Pirfenidone on Chronic Hypersensitivity Pneumonitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Stero | 2020 |
[The effects of two types of treatment on vital capacity, functional residual capacity and blood gases in idiopathic fibrosing alveolitis (author's transl)].
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Blood Gas Analysis; Drug Therapy, Combination; | 1980 |
12 other studies available for azathioprine and Allergic Alveolitis, Extrinsic
| Article | Year |
|---|---|
Use of mycophenolate mofetil and azathioprine for the treatment of chronic hypersensitivity pneumonitis-A single-centre experience.
Topics: Adrenal Cortex Hormones; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chroni | 2019 |
Impact of Azathioprine use in chronic hypersensitivity pneumonitis patients.
Topics: Adult; Aged; Aged, 80 and over; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chron | 2020 |
Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biomarkers, Pharmacological; Bronchoalveo | 2021 |
Small airway dysfunction in chronic hypersensitivity pneumonitis.
Topics: Airway Resistance; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Azathioprine; Biologica | 2017 |
Clinical case: Differential diagnosis of idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Alveolitis, Extrinsic Allergic; Azathioprine; Diagnosis, Differential; Disease Manag | 2013 |
[Severe interstitial lung disease due to treatment with infliximab and azathioprine].
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Colitis, Ulcerative; Gastrointestinal Agents; H | 2014 |
Hypersensitivity pneumonitis associated with azathioprine therapy in a patient with granulomatosis with polyangiitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Bronchoscopy; Drug Hypersensitivity; Gr | 2016 |
Use of Mycophenolate Mofetil or Azathioprine for the Management of Chronic Hypersensitivity Pneumonitis.
Topics: Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Carbon Monoxide; Chronic Disease; Female; Glucoc | 2017 |
Recurrent episodes of dermatomyositis-associated pneumonitis masquerading as hypersensitivity pneumonitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Dermatomyositis; Diagnosis, Differentia | 2006 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
[Drug-induced alveolitis associated with infliximab/azathioprine therapy].
Topics: Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Derm | 2008 |
[What is safe in the therapy of alveolitis and lung fibrosis?].
Topics: Adrenal Cortex Hormones; Alveolitis, Extrinsic Allergic; Azathioprine; Combined Modality Therapy; Cy | 1984 |