azathioprine has been researched along with Agranulocytosis in 24 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is the drug recommended for the continuation of immunosuppressive treatment after renal transplant in women during pregnancy." | 7.88 | Azathioprine-induced Agranulocytosis and Severe Alopecia After Kidney Transplantation Associated With a NUDT15 Polymorphism: A Case Report. ( Andoh, A; Ishikura, K; Kamei, K; Kano, Y; Matsumura, S; Ogura, M; Saida, K; Sato, M, 2018) |
| "We evaluated the clinical and hematologic response to methotrexate (MTX) in 4 women with Felty's syndrome (FS) who had had neutropenia for 1-3 years." | 7.67 | Reversal of neutropenia with methotrexate treatment in patients with Felty's syndrome. Correlation of response with neutrophil-reactive IgG. ( Fiechtner, JJ; Miller, DR; Starkebaum, G, 1989) |
| "Azathioprine (AZA) is the drug recommended for the continuation of immunosuppressive treatment after renal transplant in women during pregnancy." | 3.88 | Azathioprine-induced Agranulocytosis and Severe Alopecia After Kidney Transplantation Associated With a NUDT15 Polymorphism: A Case Report. ( Andoh, A; Ishikura, K; Kamei, K; Kano, Y; Matsumura, S; Ogura, M; Saida, K; Sato, M, 2018) |
| "A living related kidney transplant recipient with normal renal functioning and hypertension secondary to renal artery stenosis was treated with captopril and developed reversible granulocytopenia." | 3.67 | Captopril-associated granulocytopenia in hypertension after renal transplantation. ( Hirose, T; Jodai, A; Kuniyoshi, M; Kusaba, Y; Matsuya, F; Saito, Y; Shimomae, H; Shindo, K; Ura, T, 1984) |
| "We evaluated the clinical and hematologic response to methotrexate (MTX) in 4 women with Felty's syndrome (FS) who had had neutropenia for 1-3 years." | 3.67 | Reversal of neutropenia with methotrexate treatment in patients with Felty's syndrome. Correlation of response with neutrophil-reactive IgG. ( Fiechtner, JJ; Miller, DR; Starkebaum, G, 1989) |
| "Captopril patients had lower s-creatinine values than controls in the immediate phase after rejection." | 1.27 | Angiotensin I-converting enzyme inhibition after renal transplantation. ( Ahonen, J; Fyhrquist, F; Grönhagen-Riska, C; Häyry, P; von Willebrand, E, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saida, K | 1 |
| Kamei, K | 1 |
| Ogura, M | 1 |
| Matsumura, S | 1 |
| Kano, Y | 1 |
| Sato, M | 1 |
| Andoh, A | 1 |
| Ishikura, K | 1 |
| RIFKIND, D | 1 |
| MARCHIORO, TL | 1 |
| WADDELL, WR | 1 |
| STARZL, TE | 1 |
| Tamori, A | 1 |
| Shinzaki, M | 1 |
| Kosaka, S | 1 |
| Hayashi, T | 1 |
| Iwai, S | 1 |
| Enomoto, M | 1 |
| Habu, D | 1 |
| Sakaguchi, H | 1 |
| Kawada, N | 1 |
| Hino, M | 1 |
| Shiomi, S | 1 |
| Nishiguchi, S | 1 |
| Grönhagen-Riska, C | 1 |
| Fyhrquist, F | 1 |
| Ahonen, J | 1 |
| von Willebrand, E | 1 |
| Häyry, P | 1 |
| Shindo, K | 1 |
| Matsuya, F | 1 |
| Ura, T | 1 |
| Jodai, A | 1 |
| Shimomae, H | 1 |
| Kuniyoshi, M | 1 |
| Hirose, T | 1 |
| Kusaba, Y | 1 |
| Saito, Y | 1 |
| Bradley, PP | 1 |
| Warden, GD | 1 |
| Maxwell, JG | 1 |
| Rothstein, G | 1 |
| Inou, T | 1 |
| Kusaba, R | 1 |
| Takahashi, I | 1 |
| Sugimoto, H | 1 |
| Kuzuhara, K | 1 |
| Yamada, Y | 1 |
| Yamauchi, J | 1 |
| Otsubo, O | 1 |
| Cissoko, H | 1 |
| Jonville-Béra, AP | 1 |
| Lenain, H | 1 |
| Rivière, MF | 1 |
| Saugier, J | 1 |
| Casanova, JL | 1 |
| Autret-Leca, E | 1 |
| Sebbag, L | 1 |
| Boucher, P | 1 |
| Davelu, P | 1 |
| Boissonnat, P | 1 |
| Champsaur, G | 1 |
| Ninet, J | 1 |
| Dureau, G | 1 |
| Obadia, JF | 1 |
| Vallon, JJ | 1 |
| Delaye, J | 1 |
| Francis, GE | 1 |
| Kennedy, PG | 1 |
| Hoffbrand, BI | 1 |
| Berney, JJ | 1 |
| Hoffbrand, AV | 1 |
| Bergan, T | 1 |
| Holcombe, RF | 1 |
| Mathieson, PW | 1 |
| O'Neill, JH | 1 |
| Durrant, ST | 1 |
| Henderson, SJ | 1 |
| Green, PJ | 1 |
| Newsom-Davis, J | 1 |
| Fiechtner, JJ | 1 |
| Miller, DR | 1 |
| Starkebaum, G | 1 |
| Kolff, WJ | 1 |
| Mertens, HG | 1 |
| Balzereit, F | 1 |
| Leipert, M | 1 |
| Sánchez-Fayos, J | 2 |
| Outeirino, J | 1 |
| Serrano, J | 1 |
| Calabuig, MT | 1 |
| Paniagua, G | 1 |
| Barratt, M | 1 |
| Wallnöfer, H | 1 |
| Hanusch, M | 1 |
| Boxer, LA | 1 |
| Yokoyama, M | 1 |
| Wiebe, RA | 1 |
| Breidenbach, H | 1 |
| Krosse, C | 1 |
| Schuster, W | 1 |
| Potel, S | 1 |
| Seyfried, H | 1 |
| Górska, B | 1 |
| Maj, S | 1 |
| Sylwestrowicz, T | 1 |
| Giles, CM | 1 |
| Goldsmith, KL | 1 |
| Kölle, G | 1 |
1 review available for azathioprine and Agranulocytosis
| Article | Year |
|---|---|
Cytotoxic agents in childhood glomerulonephritis.
Topics: Adult; Agranulocytosis; Animals; Azathioprine; Child; Cyclophosphamide; Fertility; Glomerulonephriti | 1972 |
2 trials available for azathioprine and Agranulocytosis
| Article | Year |
|---|---|
Clinical trial of Bredinin in renal transplantation.
Topics: Adolescent; Adult; Agranulocytosis; Azathioprine; Child; Clinical Trials as Topic; Female; Hepatitis | 1980 |
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem | 1973 |
21 other studies available for azathioprine and Agranulocytosis
| Article | Year |
|---|---|
Azathioprine-induced Agranulocytosis and Severe Alopecia After Kidney Transplantation Associated With a NUDT15 Polymorphism: A Case Report.
Topics: Adult; Agranulocytosis; Alopecia; Azathioprine; Female; Graft Rejection; Homozygote; Humans; Immunos | 2018 |
INFECTIOUS DISEASES ASSOCIATED WITH RENAL HOMOTRANSPLANTATION.
Topics: Adolescent; Agammaglobulinemia; Agranulocytosis; Azathioprine; Bacteriophage Typing; Child; Diagnosi | 1964 |
Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases.
Topics: Adult; Aged; Agranulocytosis; Asian People; Azathioprine; Bone Marrow; Female; Gastrointestinal Dise | 2007 |
Angiotensin I-converting enzyme inhibition after renal transplantation.
Topics: Adult; Agranulocytosis; Angiotensin-Converting Enzyme Inhibitors; Azathioprine; Blood Pressure; Capt | 1984 |
Captopril-associated granulocytopenia in hypertension after renal transplantation.
Topics: Adult; Agranulocytosis; Azathioprine; Captopril; Humans; Hypertension, Renovascular; Kidney Transpla | 1984 |
Neutropenia and thrombocytopenia in renal allograft recipients treated with trimethoprim-sulfamethoxazole.
Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Drug Combinations; Drug Synergism; Humans; Kidney | 1980 |
[Agranulocytosis and transitory immune deficiency after fetal exposure to azathioprine and mesalazine].
Topics: Adult; Agammaglobulinemia; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; C | 1999 |
Thiopurine S-methyltransferase gene polymorphism is predictive of azathioprine-induced myelosuppression in heart transplant recipients.
Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Female; Forecasting; Genetic Predisposition to Di | 2000 |
Response of neutropenia and anaemia to immunosuppressive therapy: report and bone marrow culture studies.
Topics: Agranulocytosis; Anemia; Azathioprine; Bone Marrow; Colony-Forming Units Assay; Colony-Stimulating F | 1979 |
Neutropenia associated with metronidazole.
Topics: Agranulocytosis; Azathioprine; Drug Therapy, Combination; Humans; Metronidazole; Neutropenia | 1979 |
Drug-induced granulocytopenia with natural killer lymphocytosis after renal transplantation.
Topics: Adult; Agranulocytosis; Azathioprine; Cimetidine; Cytomegalovirus Infections; Drug Therapy, Combinat | 1990 |
Antibody-mediated pure neutrophil aplasia, recurrent myasthenia gravis and previous thymoma: case report and literature review.
Topics: Adult; Agranulocytosis; Antibodies; Azathioprine; Bone Marrow; Female; Humans; Immunosuppression The | 1990 |
Reversal of neutropenia with methotrexate treatment in patients with Felty's syndrome. Correlation of response with neutrophil-reactive IgG.
Topics: Aged; Agranulocytosis; Azathioprine; Enzyme-Linked Immunosorbent Assay; Felty Syndrome; Female; Huma | 1989 |
[Hemodialysis and kidney transplantation].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Agranulocytosis; Azathioprine; Dactinomycin; Humans; H | 1965 |
The treatment of severe myasthenia gravis with immunosuppressive agents.
Topics: Adolescent; Adult; Age Factors; Agranulocytosis; Aminopterin; Azathioprine; Chemical and Drug Induce | 1969 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Anemia, Hemolytic, Autoimmune | 1970 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Agranulocytosis; Anemia, He | 1970 |
Autoimmune neutropenia associated with chronic active hepatitis.
Topics: Agranulocytosis; Autoantibodies; Autoimmune Diseases; Azathioprine; Child; Chromatography, DEAE-Cell | 1972 |
[Therapy of autoimmune thrombocytopenia in childhood].
Topics: Agranulocytosis; Autoimmune Diseases; Azathioprine; Child; Cushing Syndrome; Humans; Prednisone; Spl | 1972 |
Apparent depression of antigens of the Kell blood group system associated with autoimmune acquired haemolytic anaemia.
Topics: Adolescent; Agranulocytosis; Anemia, Hemolytic, Autoimmune; Azathioprine; Blood Group Antigens; Bloo | 1972 |
[Bone marrow damage following immunosuppressive therapy with azathioprine of juvenile rheumatoid arthritis and the Still syndrome].
Topics: Adolescent; Agranulocytosis; Arthritis, Juvenile; Azathioprine; Bone Marrow Diseases; Bone Marrow Ex | 1969 |