azathioprine has been researched along with Aging in 16 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine was also introduced earlier (20." | 1.30 | [Diffuse jejuno-ileitis of Crohn's disease: a separate form of the disease?]. ( Colombel, JF; Cortot, A; Gower-Rousseau, C; Grandbastien, B; Paris, JC; Quandalle, P; Touze, I, 1999) |
| "Thymoma was more common in the older population; these patients did no worse than the population as a whole." | 1.28 | The relationship of age to outcome in myasthenia gravis. ( Ansher, M; Donaldson, DH; Horan, S; Ringel, SP; Rutherford, RB, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willington, AJ | 1 |
| Gearry, RB | 1 |
| Broekman, MMTJ | 1 |
| Wanten, GJ | 1 |
| de Jong, DJ | 1 |
| Loit, E | 1 |
| Tricco, AC | 1 |
| Tsouros, S | 1 |
| Sears, M | 1 |
| Ansari, MT | 1 |
| Booth, RA | 1 |
| Walford, RL | 1 |
| Peters, TG | 1 |
| Charlton, RK | 1 |
| Jones, KW | 1 |
| Goodrich, JP | 1 |
| Sill, TM | 1 |
| King, TB | 1 |
| Touze, I | 1 |
| Gower-Rousseau, C | 1 |
| Grandbastien, B | 1 |
| Paris, JC | 1 |
| Quandalle, P | 1 |
| Cortot, A | 1 |
| Colombel, JF | 1 |
| Menahan, LA | 1 |
| Kemp, RG | 1 |
| Bach, JF | 1 |
| Dardenne, M | 1 |
| Pleau, JM | 1 |
| Bach, MA | 1 |
| Gershwin, ME | 1 |
| Steinberg, AD | 1 |
| Woody, JN | 1 |
| Ahmed, A | 1 |
| Donaldson, DH | 1 |
| Ansher, M | 1 |
| Horan, S | 1 |
| Rutherford, RB | 1 |
| Ringel, SP | 1 |
| Leunissen, KM | 1 |
| Bosman, FT | 1 |
| Kootstra, G | 1 |
| van Hooff, JP | 1 |
| Hayes, JM | 1 |
| Novick, AC | 1 |
| Steinmuller, DR | 1 |
| Streem, SB | 1 |
| Hodge, EE | 1 |
| Bretan, PN | 1 |
| Cunningham, R | 1 |
| Graneto, D | 1 |
| Trivedi, P | 1 |
| Cheeseman, P | 1 |
| Portmann, B | 1 |
| Hegarty, J | 1 |
| Mowat, AP | 1 |
| Bailey, GL | 1 |
| Mocelin, AJ | 1 |
| Griffiths, HJ | 1 |
| Zschaeck, D | 1 |
| Ghantous, WN | 1 |
| Hampers, CL | 1 |
| Merrill, JP | 1 |
| Wilson, RE | 1 |
| Hurley, RM | 1 |
| Drummond, KN | 1 |
| Bender, AD | 1 |
| Kormendy, CG | 1 |
| Powell, R | 1 |
2 reviews available for azathioprine and Aging
| Article | Year |
|---|---|
Pre-analytic and analytic sources of variations in thiopurine methyltransferase activity measurement in patients prescribed thiopurine-based drugs: A systematic review.
Topics: Aging; Azathioprine; Enzyme Stability; Health Care Surveys; Hematocrit; Humans; Mercaptopurine; Meth | 2011 |
Pharmacological control of aging.
Topics: Aging; Allergy and Immunology; Animals; Antioxidants; Azathioprine; Cell Biology; Central Nervous Sy | 1970 |
14 other studies available for azathioprine and Aging
| Article | Year |
|---|---|
Editorial: thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype-the perils of ageing.
Topics: Aging; Azathioprine; Genotype; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercap | 2018 |
Editorial: thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype-the perils of ageing. Authors' reply.
Topics: Aging; Azathioprine; Genotype; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercap | 2018 |
The role of autoimmune phenomena in the ageing process.
Topics: Aging; Amyloidosis; Animals; Appendix; Autoantibodies; Azathioprine; Cricetinae; Fishes; Hemolysin P | 1967 |
Kidney transplantation in the older patient.
Topics: Aged; Aging; Azathioprine; Cause of Death; Cyclosporine; Female; Florida; Follow-Up Studies; Graft R | 1994 |
[Diffuse jejuno-ileitis of Crohn's disease: a separate form of the disease?].
Topics: Adolescent; Adult; Aging; Azathioprine; Crohn Disease; Enteritis; Female; Humans; Ileal Diseases; Je | 1999 |
The effect of several lymphocytotoxic agents on murine leukemogenesis.
Topics: Aging; Animals; Azathioprine; Body Weight; Cortisone; Dacarbazine; Leukemia, Experimental; Lymphocyt | 1978 |
Isolation, biochemical characteristics, and biological activity of a circulating thymic hormone in the mouse and in the human.
Topics: Aging; Animals; Antilymphocyte Serum; Arthritis, Rheumatoid; Autoantibodies; Azathioprine; Cell-Free | 1975 |
Studies of thymic factors. I. Evaluation of the mouse rosette assay for thymic hormone.
Topics: Aging; Animals; Antilymphocyte Serum; Azathioprine; DNA, Single-Stranded; Female; Immune Adherence R | 1975 |
The relationship of age to outcome in myasthenia gravis.
Topics: Adrenal Cortex Hormones; Aged; Aging; Antibodies; Autoimmune Diseases; Azathioprine; Combined Modali | 1990 |
The effect of cyclosporine A on renal graft function is dependent on donor age.
Topics: Aging; Azathioprine; Cyclosporins; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Predniso | 1988 |
Improved results using pediatric cadaver donor kidneys with cyclosporine immunosuppression.
Topics: Aging; Antilymphocyte Serum; Azathioprine; Child, Preschool; Cyclosporins; Drug Administration Sched | 1988 |
Variation in serum type III procollagen peptide with age in healthy subjects and its comparative value in the assessment of disease activity in children and adults with chronic active hepatitis.
Topics: Adolescent; Adult; Aged; Aging; Azathioprine; Child; Child, Preschool; Hepatitis, Chronic; Humans; I | 1985 |
Hemodialysis and renal transplantation in patients of the 50-80 age group.
Topics: Aged; Aging; Azathioprine; Blood Glucose; Cysts; Diabetes Mellitus; Female; Glomerulonephritis; Gluc | 1972 |
Glomerular enlargement in primary renal disease: a quantitative study.
Topics: Adolescent; Adult; Age Factors; Aging; Autopsy; Azathioprine; Biopsy; Child; Child, Preschool; Cyclo | 1974 |