azathioprine has been researched along with Adult-Onset Still Disease in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is characterized by high interindividual differences in bioavailability and metabolization." | 1.31 | Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. ( Decaux, G; Desager, JP; Horsmans, Y; Prospert, F, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, HM | 1 |
| Liu, MF | 1 |
| Chang, KK | 1 |
| Liu, SM | 1 |
| Chen, CH | 1 |
| Nordström, D | 1 |
| Knight, A | 1 |
| Luukkainen, R | 1 |
| van Vollenhoven, R | 1 |
| Rantalaiho, V | 1 |
| Kajalainen, A | 1 |
| Brun, JG | 1 |
| Proven, A | 1 |
| Ljung, L | 1 |
| Kautiainen, H | 1 |
| Pettersson, T | 1 |
| Krzossok, S | 1 |
| Benck, U | 1 |
| van der Woude, FJ | 1 |
| Braun, C | 1 |
| Cefle, A | 1 |
| Cheema, GS | 1 |
| Quismorio, FP | 1 |
| Decaux, G | 1 |
| Prospert, F | 1 |
| Horsmans, Y | 1 |
| Desager, JP | 1 |
| Crétel, E | 1 |
| Richard, MA | 1 |
| Jean, R | 1 |
| Durand, JM | 1 |
| Hatz, HJ | 1 |
| Löffler, W | 1 |
| Mohr, M | 1 |
| Lindlbauer, R | 1 |
| Helmke, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open, Randomized Study Treating Refractory Adult-onset Still's Disease With Interleukin-1 Receptor Antagonist Anakinra (Kineret), Compared to an Established, Single Anti-rheumatic Drug Treatment[NCT01033656] | Phase 2 | 23 participants (Actual) | Interventional | 2005-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Adult-Onset Still Disease
| Article | Year |
|---|---|
Pulmonary involvement in adult-onset Still's disease.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Chronic Disease; Cyclophosphamide; Humans; Immunoglobu | 1999 |
1 trial available for azathioprine and Adult-Onset Still Disease
| Article | Year |
|---|---|
Beneficial effect of interleukin 1 inhibition with anakinra in adult-onset Still's disease. An open, randomized, multicenter study.
Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Humans; Interleukin 1 Receptor Antagonist Protein | 2012 |
6 other studies available for azathioprine and Adult-Onset Still Disease
| Article | Year |
|---|---|
Adult-onset Still's disease complicated with hemophagocytic syndrome.
Topics: Azathioprine; Bone Marrow; Drug Therapy, Combination; Female; Fever; Glucocorticoids; Humans; Immuno | 2010 |
[Disseminated intravascular coagulation, perimyocarditis and bilateral pleural empyema in adult Still's disease].
Topics: Adult; Azathioprine; Disseminated Intravascular Coagulation; Electrocardiography; Empyema, Pleural; | 2004 |
Leflunomide and azathioprine combination in refractory adult-onset Still's disease.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Still's Dis | 2005 |
Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine.
Topics: Adult; Azathioprine; Biological Availability; Churg-Strauss Syndrome; Erythrocyte Indices; Erythrocy | 2000 |
Still's-like disease, breast prosthesis, and collagen implants.
Topics: Azathioprine; Breast; Breast Implants; Collagen; Female; Ferritins; Glucocorticoids; Glycosylation; | 2001 |
[Therapy strategies for Still's syndrome of adults (AOSD)].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic | 1991 |