azathioprine has been researched along with Adenomatous Polyposis Coli in 3 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All azathioprine treated mice showed signs of drug-associated toxicity such as weight loss and development of splenic T-cell lymphomas." | 3.80 | Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis. ( D'Haens, GR; Heijmans, J; Jansen, M; Levin, AD; Muncan, V; Rosekrans, SL; Schukking, M; van den Brink, GR; van Lidth de Jeude, JF; Wielenga, MC, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galatola, M | 1 |
| Miele, E | 1 |
| Strisciuglio, C | 1 |
| Paparo, L | 1 |
| Rega, D | 1 |
| Delrio, P | 1 |
| Duraturo, F | 1 |
| Martinelli, M | 1 |
| Rossi, GB | 1 |
| Staiano, A | 1 |
| Izzo, P | 1 |
| De Rosa, M | 1 |
| Wielenga, MC | 1 |
| van Lidth de Jeude, JF | 1 |
| Rosekrans, SL | 1 |
| Levin, AD | 1 |
| Schukking, M | 1 |
| D'Haens, GR | 1 |
| Heijmans, J | 1 |
| Jansen, M | 1 |
| Muncan, V | 1 |
| van den Brink, GR | 1 |
| Kitamura, A | 1 |
| Kanagawa, T | 1 |
| Yamada, S | 1 |
| Kawai, T | 1 |
3 other studies available for azathioprine and Adenomatous Polyposis Coli
| Article | Year |
|---|---|
Synergistic effect of interleukin-10-receptor variants in a case of early-onset ulcerative colitis.
Topics: Adenomatous Polyposis Coli; Age of Onset; Anti-Infective Agents; Azathioprine; beta Catenin; Biomark | 2013 |
Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Azathioprine; Female; Genes, APC; Lymp | 2014 |
Effective chemotherapy for abdominal desmoid tumor in a patient with Gardner's syndrome. Report of a case.
Topics: Abdominal Neoplasms; Adenomatous Polyposis Coli; Adult; Antineoplastic Combined Chemotherapy Protoco | 1991 |