azathioprine has been researched along with Adenocarcinoma in 34 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Efficacy and safety of azathioprine in 'high' and 'low' dose regimens in rheumatoid arthritis (RA), both in short-term studies and in follow-up over 40 months, have previously been shown." | 7.66 | Long-term effects of azathioprine in rheumatoid arthritis. ( Able, T; Norman, CS; Smythe, HA; Travis, C; Urowitz, MB, 1982) |
| " In two patients the corticosteroid dosage could be tapered." | 5.27 | Cutaneous lesions of dermatomyositis are improved by hydroxychloroquine. ( Bickers, DR; Callen, JP; Hanno, R; Hawkins, C; Voorhees, JJ; Woo, TY, 1984) |
| "Efficacy and safety of azathioprine in 'high' and 'low' dose regimens in rheumatoid arthritis (RA), both in short-term studies and in follow-up over 40 months, have previously been shown." | 3.66 | Long-term effects of azathioprine in rheumatoid arthritis. ( Able, T; Norman, CS; Smythe, HA; Travis, C; Urowitz, MB, 1982) |
| "Strikingly, metastasis was dramatically reduced in Vav1-expressing tumors arising from p48(Cre/+), Kras(G12D/+), p53(F/+) mice." | 1.42 | Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion. ( Almada, LL; Fernandez-Zapico, ME; Hurley, RM; Ji, B; Magnine, C; McNiven, MA; Razidlo, GL; Sletten, AC, 2015) |
| "The risk of colorectal cancer was not increased, either in the total group of patients or in patients with colonic Crohn's disease exclusively (standardized morbidity ratio, 1." | 1.32 | Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark. ( Binder, V; Jess, T; Langholz, E; Munkholm, P; Winther, KV, 2004) |
| "Among patients with extensive chronic ulcerative colitis there was no difference in cancer frequency between 86 who had received azathioprine and 180 matched patients who had never received it." | 1.29 | Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease. ( Balkwill, AM; Connell, WR; Dickson, M; Kamm, MA; Lennard-Jones, JE; Ritchie, JK, 1994) |
| " In two patients the corticosteroid dosage could be tapered." | 1.27 | Cutaneous lesions of dermatomyositis are improved by hydroxychloroquine. ( Bickers, DR; Callen, JP; Hanno, R; Hawkins, C; Voorhees, JJ; Woo, TY, 1984) |
| "Azathioprine was administered to 25 patients with severe, progressive polyarthritis in a mean dose of 1." | 1.26 | Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients. ( Pinals, RS, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (58.82) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Andersson, P | 1 |
| Norblad, R | 1 |
| Söderholm, JD | 1 |
| Myrelid, P | 1 |
| Chapman, CG | 1 |
| Rubin, DT | 1 |
| Canha, C | 1 |
| Ferreira, R | 1 |
| Rovira, J | 1 |
| Moya-Rull, D | 1 |
| Castells, A | 1 |
| Diekmann, F | 1 |
| Oppenheimer, F | 1 |
| Campistol, JM | 1 |
| Revuelta, I | 1 |
| Razidlo, GL | 1 |
| Magnine, C | 1 |
| Sletten, AC | 1 |
| Hurley, RM | 1 |
| Almada, LL | 1 |
| Fernandez-Zapico, ME | 1 |
| Ji, B | 1 |
| McNiven, MA | 1 |
| Damaso, CR | 1 |
| Oliveira, MF | 1 |
| Massarani, SM | 1 |
| Moussatché, N | 1 |
| Miravet Sorribes, L | 1 |
| Vidal Villalón, G | 1 |
| Ortega Roig, M | 1 |
| Ballester Fayos, J | 1 |
| Gainon, J | 1 |
| Bart, PA | 1 |
| Waeber, G | 1 |
| Jess, T | 1 |
| Winther, KV | 1 |
| Munkholm, P | 1 |
| Langholz, E | 1 |
| Binder, V | 1 |
| Sasaki, J | 1 |
| Kawamura, YJ | 1 |
| Konishi, F | 1 |
| Tosha, T | 1 |
| Kronberger, IE | 1 |
| Graziadei, IW | 1 |
| Vogel, W | 1 |
| Urowitz, MB | 1 |
| Smythe, HA | 1 |
| Able, T | 1 |
| Norman, CS | 1 |
| Travis, C | 1 |
| Woo, TY | 1 |
| Callen, JP | 1 |
| Voorhees, JJ | 1 |
| Bickers, DR | 1 |
| Hanno, R | 1 |
| Hawkins, C | 1 |
| Connell, WR | 1 |
| Kamm, MA | 1 |
| Dickson, M | 1 |
| Balkwill, AM | 1 |
| Ritchie, JK | 1 |
| Lennard-Jones, JE | 1 |
| Amato, MP | 1 |
| Pracucci, G | 1 |
| Ponziani, G | 1 |
| Siracusa, G | 1 |
| Fratiglioni, L | 1 |
| Amaducci, L | 1 |
| Schaller, M | 1 |
| Korting, HC | 1 |
| Meurer, M | 1 |
| Schirren, CG | 1 |
| Westaby, S | 1 |
| Everett, WG | 1 |
| Dick, AP | 1 |
| Elliott, GB | 1 |
| Silverberg, DS | 1 |
| Dossetor, JB | 1 |
| Muir, CS | 1 |
| Hodgkinson, DJ | 1 |
| Williams, TJ | 2 |
| Pinals, RS | 1 |
| Shorter, RG | 1 |
| Shephard, DA | 1 |
| Sekiya, S | 1 |
| Iwasaki, H | 1 |
| Takeda, B | 1 |
| Takamizawa, H | 1 |
| Polson, RJ | 1 |
| Neuberger, J | 1 |
| Forman, D | 1 |
| Calne, R | 1 |
| Williams, R | 1 |
| Letsou, G | 1 |
| Ballantyne, GH | 1 |
| Zdon, IM | 1 |
| Cambria, RM | 1 |
| Modlin, IM | 1 |
| San José, A | 1 |
| Valdés, M | 1 |
| Oristrell, J | 1 |
| Knobel, H | 1 |
| Bosch, JA | 1 |
| Belzer, FO | 1 |
| Schweizer, RT | 1 |
| Kountz, SL | 1 |
| DeLorimier, AA | 1 |
| Prejean, JD | 1 |
| Griswold, DP | 1 |
| Weisburger, JH | 1 |
| Birtch, AG | 1 |
| Moore, FD | 1 |
| Birkeland, SA | 1 |
| Kemp, E | 1 |
| Kim, HH | 1 |
| Cerilli, J | 1 |
| Hattan, D | 1 |
| Dargent, M | 1 |
| Bourgoin, JJ | 1 |
| Noel, P | 1 |
| Weissbrod, R | 1 |
| Walker, D | 1 |
| Gill, TJ | 1 |
| Corson, JM | 1 |
| Joseph, WL | 1 |
| Melewicz, F | 1 |
| Morton, DL | 1 |
4 reviews available for azathioprine and Adenocarcinoma
| Article | Year |
|---|---|
The potential for medical therapy to reduce the risk of colorectal cancer and optimize surveillance in inflammatory bowel disease.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; | 2014 |
Small bowel adenocarcinoma in Crohn's disease: a case report and review of literature.
Topics: Adenocarcinoma; Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Humans; | 2006 |
Experience in liver transplantation.
Topics: Adenocarcinoma; Adolescent; Adult; Alkalosis; Animals; Antilymphocyte Serum; Azathioprine; Blood Coa | 1969 |
Immunology in neoplasia relating to diagnosis, therapy and transplantation. Immunosuppression and oncogenesis.
Topics: Adenocarcinoma; Animals; Antilymphocyte Serum; Azathioprine; Carcinogens; Cortisone; Humans; Immunos | 1974 |
30 other studies available for azathioprine and Adenocarcinoma
| Article | Year |
|---|---|
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Ileorectal anastomosis in comparison with ileal pouch anal anastomosis in reconstructive surgery for ulcerative colitis--a single institution experience.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adolescent; Adrenal Cortex Hormones; Adult; Anastomosis, Surgic | 2014 |
A case of esophageal adenocarcinoma on long-term rapamycin monotherapy.
Topics: Adenocarcinoma; Aged; Azathioprine; Biomarkers; Cyclosporine; Drug Substitution; Esophageal Neoplasm | 2015 |
Targeting Pancreatic Cancer Metastasis by Inhibition of Vav1, a Driver of Tumor Cell Invasion.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azathioprine; Female; Humans; Mice; Mice, Nude; Mice | 2015 |
Azathioprine inhibits vaccinia virus replication in both BSC-40 and RAG cell lines acting on different stages of virus cycle.
Topics: Adenocarcinoma; Animals; Azathioprine; Cell Line; Chlorocebus aethiops; DNA Replication; Genes, Vira | 2002 |
[Lung adenocarcinoma, inflammatory bowel disease and azathioprine].
Topics: Adenocarcinoma; Autopsy; Azathioprine; Colitis, Ulcerative; Fatal Outcome; Humans; Lung Neoplasms; M | 2003 |
[Can we predict the risk of malignancy associated with dermatomyositis?].
Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprin | 2003 |
Intestinal and extra-intestinal cancer in Crohn's disease: follow-up of a population-based cohort in Copenhagen County, Denmark.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hor | 2004 |
Colitic cancer developed after introduction of azathioprine.
Topics: Adenocarcinoma; Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; Fatal Outc | 2004 |
Long-term effects of azathioprine in rheumatoid arthritis.
Topics: Adenocarcinoma; alpha-Fetoproteins; Arthritis, Rheumatoid; Azathioprine; Chromosome Aberrations; Dos | 1982 |
Cutaneous lesions of dermatomyositis are improved by hydroxychloroquine.
Topics: Adenocarcinoma; Adolescent; Adult; Azathioprine; Dermatomyositis; Drug Therapy, Combination; Female; | 1984 |
Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Azathioprine; Colitis, Ulcerative; Crohn Disease; Fe | 1994 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
[Generalized Mycobacterium avium-intracellulare infection due to immunosuppressive therapy of paraneoplastic dermatomyositis].
Topics: Adenocarcinoma; Azathioprine; Biopsy; Breast Neoplasms; Dermatomyositis; Female; Fluocortolone; Huma | 1997 |
Adenocarcinoma of the small bowel complicating Crohn's disease in a patient treated with azathioprine.
Topics: Adenocarcinoma; Azathioprine; Crohn Disease; Female; Humans; Intestinal Neoplasms; Intestine, Small; | 1977 |
Latent carcinoma of the prostate in a 24-year-old man receiving cyclophosphamide and azathioprine.
Topics: Adenocarcinoma; Adult; Azathioprine; Cyclophosphamide; Glomerulonephritis; Humans; Male; Prednisone; | 1977 |
Endometrial carcinoma associated with azathioprine and cortisone therapy. A case report.
Topics: Adenocarcinoma; Adult; Amenorrhea; Azathioprine; Female; Genital Neoplasms, Female; Humans; Immunity | 1977 |
Azathioprine in the treatment of chronic polyarthritis: longterm results and adverse effects in 25 patients.
Topics: Adenocarcinoma; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Carcinoma; Femal | 1976 |
Frontiers in inflammatory bowel disease. The proceedings of a conference sponsored by the McReynolds Foundation. Part II.
Topics: Adenocarcinoma; Arthritis; Azathioprine; Child; Chronic Disease; Colitis, Ulcerative; Colonic Neopla | 1975 |
Endometrial carcinoma following chronic anovulation in a premenopausal woman with systemic lupus erythematosus.
Topics: Adenocarcinoma; Adult; Anovulation; Azathioprine; Endometrium; Female; Humans; Hyperplasia; Lupus Er | 1988 |
De novo malignancies after liver transplantation.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Azathioprine; Child; Colonic Neoplasms; Cyclosporins; Dysge | 1988 |
Rectal carcinoma in a renal transplant patient. Long-term complication of immunosuppression?
Topics: Adenocarcinoma; Azathioprine; Barium Sulfate; Colonic Neoplasms; Enema; Humans; Immunosuppressive Ag | 1986 |
[Polymyositis, immunosuppressive treatment and cardia neoplasms: casual or causal relation].
Topics: Adenocarcinoma; Azathioprine; Cardia; Humans; Male; Middle Aged; Myositis; Stomach Neoplasms | 1985 |
Malignancy and immunosuppression. Renal homotransplantation in patients with primary renal neoplasms.
Topics: Adenocarcinoma; Adult; Azathioprine; Child, Preschool; Female; Humans; Immunosuppression Therapy; In | 1972 |
Transplantation of allogeneic tumors in rats and mice treated with azathioprine, prednisone and antilymphocyte serum.
Topics: Adenocarcinoma; Animals; Antilymphocyte Serum; Azathioprine; Carcinoma, Hepatocellular; Immunosuppre | 1972 |
Malignant tumours following immunosuppression in renal transplantation.
Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom | 1973 |
Endometrioid carcinoma of the uterus and ovaries associated with immunosuppressive therapy and anticoagulation: report of a case.
Topics: Adenocarcinoma; Adult; Amenorrhea; Anticoagulants; Azathioprine; Endometriosis; Female; Humans; Immu | 1972 |
The influence of azathioprine on tumorogenesis by 7-12 dimethylbenz (a) anthracene in rats.
Topics: Adenocarcinoma; Adenofibroma; Animals; Azathioprine; Benz(a)Anthracenes; Carcinoma; Female; Fibroma; | 1972 |
Leiomyosarcoma in a renal allograft recipient treated with immunosuppressive drugs.
Topics: Adenocarcinoma; Adult; Age Factors; Autopsy; Azathioprine; Histocompatibility; Humans; Immunosuppres | 1971 |
Spontaneous development of mammary adenocarcinoma following prolonged immunosuppression in the dog.
Topics: Adenocarcinoma; Animals; Azathioprine; Chlorine; Dogs; Female; Hypersensitivity, Delayed; Mammary Ne | 1970 |