Page last updated: 2024-10-23

azathioprine and Acute Kidney Injury

azathioprine has been researched along with Acute Kidney Injury in 74 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"With its incidence of about 40%, acute renal failure (ARF) is a major problem after cadaveric renal transplantation."6.66Mannitol as an indispensable constituent of an intraoperative hydration protocol for the prevention of acute renal failure after renal cadaveric transplantation. ( Berden, JH; Hoitsma, AJ; Koene, RA; Tiggeler, RG; van Lier, HJ; van Valenberg, PL, 1987)
"The outcome of patients with acute renal failure following cadaveric renal transplant has been evaluated in a prospective, controlled trial, comparing treatment with cyclosporine (CSA) to prednisone, azathioprine, and antilymphocyte globulin (AZA)."5.05Post-transplant acute renal failure in cadaver renal recipients treated with cyclosporine. ( Duggin, GG; Farnsworth, A; Hall, BM; Horvath, JS; Johnson, JR; May, J; Sheil, AG; Tiller, DJ, 1985)
" The factors associated with a lower probability of recovery included a previous history of LN flares, worse eGFR and higher proteinuria at presentation, immunosuppression with azathioprine, and hospitalizations within 6 months of therapy initiation."4.31Predictors of treatment outcomes in lupus nephritis with severe acute kidney injury and requirement of dialytic support. ( Juárez-Cuevas, B; Márquez-Macedo, SE; Mejía-Vilet, JM; Morales-Buenrostro, LE; Navarro-Gerrard, MA; Pena-Vizcarra, ÓR; Perez-Arias, AA; Zavala-Miranda, MF, 2023)
" The younger patient had the diagnosis confirmed at an early stage by renal biopsy, and under heparin and azathioprine the clinical signs, especially the nephrotic syndrome, regressed over a period of seven months."3.65[Amyloidosis in familial mediterranean fever: clinical and renal-biopsy features (author's transl)]. ( Angelkort, B; Brass, H; Buss, H; Heintz, R; Klein, H; Lapp, H, 1976)
"With its incidence of about 40%, acute renal failure (ARF) is a major problem after cadaveric renal transplantation."2.66Mannitol as an indispensable constituent of an intraoperative hydration protocol for the prevention of acute renal failure after renal cadaveric transplantation. ( Berden, JH; Hoitsma, AJ; Koene, RA; Tiggeler, RG; van Lier, HJ; van Valenberg, PL, 1987)
"Azathioprine has equivalent efficacy as a maintenance agent to cyclophosphamide with fewer episodes of leucopenia."2.52Interventions for renal vasculitis in adults. ( Craig, JC; Walters, G; Willis, NS, 2015)
"A 36-year-old woman with systemic lupus erythematosus was admitted to our hospital with malaise, myalgia, dysphagia, fever, preserved muscle strength, leukocytosis (15,600 cells), and increased creatine kinase of 1,358 IU/L that reached 75,000 IU/L in few days."1.37Fatal rhabdomyolysis in systemic lupus erythematosus. ( Bonfa, E; da Mota, LM; de Carvalho, JF, 2011)
"Treatment with prednisolone alone or with a prednisolone/azathioprine combination resulted in an equal five-year survival (82%) and a similar overall preservation of renal function."1.27Renal involvement in systemic lupus erythematosus. ( Atkins, RC; Boyce, NW; Holdsworth, SR; Thomson, NM, 1984)
"Course and treatment of a case of Wegener's granulomatosis are reported."1.27[Wegener's granulomatosis as a rare cause for kidney failure]. ( Asamer, H; Bolzano, K; Krempler, F; Sandhofer, F, 1983)
" In group II, cyclosporine was started only after the procedure at a lower dosage and was complemented by azathioprine, which was used for the first postoperative week."1.27Cardiac transplantation: improved quality of survival with a modified immunosuppressive protocol. ( Bahnson, HT; Griffith, BP; Hardesty, RL; Kormos, RL; Thompson, ME; Trento, A, 1987)
" Although one patient subsequently required chronic dialysis, reduction of cyclosporine dosage from a mean of 5."1.27Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients. ( Bahnson, HT; Bernstein, RL; Egel, JW; Greenberg, A; Griffith, BP; Hardesty, RL; Hastillo, A; Hess, ML; Puschett, JB; Thompson, ME, 1987)
"Severe acute renal failure developed in a patient with systemic lupus erythematosus which was characterized by typical skin rash, polyserositis, haemolytic anaemia and liver damage."1.25[Haemodialysis for renal failure in a case of systemic lupus erythematosus (author's transl)]. ( Kopsa, H; Schmidt, P; Zazgornik, J, 1975)
"Nephrosclerosis was found in both kidneys."1.25[Peracute primary malignant nephrosclerosis with irreversible kidney failure and malignant hypertension following ovulation inhibitors]. ( Bock, KD; Bohle, A, 1973)
"Acute anuric renal failure complicating systemic lupus erythematosus does not usually respond to treatment with corticosteroids and immunosuppressive agents."1.25Acute renal failure in systemic lupus erythematosus. ( Brancaccio, D; Imbasciati, E; Ponticelli, C; Rivolta, E; Tarantino, A, 1974)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199058 (78.38)18.7374
1990's6 (8.11)18.2507
2000's3 (4.05)29.6817
2010's5 (6.76)24.3611
2020's2 (2.70)2.80

Authors

AuthorsStudies
Márquez-Macedo, SE1
Perez-Arias, AA1
Pena-Vizcarra, ÓR1
Zavala-Miranda, MF1
Juárez-Cuevas, B1
Navarro-Gerrard, MA1
Morales-Buenrostro, LE1
Mejía-Vilet, JM1
Walters, GD1
Willis, NS3
Cooper, TE1
Craig, JC3
Walters, G2
Ayoub, I1
Almaani, S1
Alvarado, A1
Parikh, SV1
Rovin, BH1
Awdishu, L1
Joy, MS1
Benseler, SM1
Bargman, JM1
Feldman, BM1
Tyrrell, PN1
Harvey, E1
Hebert, D1
Silverman, ED1
de Carvalho, JF1
da Mota, LM1
Bonfa, E1
Lien, YH1
Bracamonte, ER1
Ahmed, E1
Akhtar, F1
Hashmi, A1
Imtiaz, S1
Hussain, Z1
Hafeez, S1
Naqvi, A1
Rizvi, A1
QUIJANO, M1
GOMEZMONT, F1
ORTIZQUEZADA, F1
RONCES, R1
HAMBURGER, J1
CROSNIER, J2
DORMONT, J1
Flechner, SM1
Payne, WD1
Van Buren, C1
Kerman, R1
Kahan, BD1
Boyce, NW1
Holdsworth, SR1
Thomson, NM1
Atkins, RC1
Evans, TW1
Nicholls, AJ1
Shortland, JR1
Ward, AM1
Brown, CB1
Krempler, F1
Asamer, H1
Bolzano, K1
Sandhofer, F1
Lundgren, G1
Asaba, H1
Bergström, J1
Groth, CG1
Magnusson, G1
Möller, E1
Strindberg, J1
Wehle, B1
Wańkowicz, Z1
Kałczak, M1
Panasiuk, E1
Ciszkiewicz, Z1
Porayko, MK1
Textor, SC1
Krom, RA1
Hay, JE1
Gores, GJ1
Richards, TM1
Crotty, PH1
Beaver, SJ1
Steers, JL1
Wiesner, RH1
Woodle, ES1
Perdrizet, GA1
So, S1
Jendrisak, MD1
White, HM1
Marsh, JW1
McHenry, PM1
Allan, JG1
Rodger, RS1
Lever, RS1
Fields, CL1
Robinson, JW1
Roy, TM1
Ossorio, MA1
Byrd, RP1
Schmidt, P1
Kopsa, H1
Zazgornik, J1
Lawson, RK2
Talwalkar, YB1
Musgrave, JE1
Campbell, RA2
Hodges, CV2
Bakshandeh, K1
Picache, R1
Bastounis, E1
Haberal, MA1
Husberg, BS1
Kaplan, BS1
Chassot, PG1
Knaack, J1
Morehouse, D1
Beaudoin, JG1
Guttmann, RD1
Delmonico, FL1
Cosimi, AB1
Russell, PS1
Brass, H1
Klein, H1
Buss, H1
Lapp, H1
Heintz, R1
Angelkort, B1
Boratyńska, M1
Szepietowski, T1
Szewczyk, Z1
Szydłowski, Z1
Steinmuller, DR1
Hayes, JM1
Novick, AC1
Streem, SB1
Hodge, E1
Slavis, S1
Martinez, A1
Graneto, D1
Pearce, G1
Vouhé, PR1
Le Bidois, J1
Dartevelle, P1
Touati, G1
Pouard, P1
Mauriat, P1
Jayais, P1
Sidi, D1
Kachaner, J1
Neveux, JY1
Lipkowitz, GS1
Hong, JH1
Galishoff, ML1
McMillen, M1
Sumrani, N1
Hanson, P1
Tejani, A1
Butt, KM1
Ricart, MJ1
Andreu, J1
Oppenheimer, F1
Vilardell, J1
Sans, A1
Orihuela, S1
Fischer, J1
Kirste, G1
Keller, H1
Wilms, H1
van Valenberg, PL1
Hoitsma, AJ1
Tiggeler, RG1
Berden, JH1
van Lier, HJ1
Koene, RA1
Ponticelli, C3
Minetti, L1
Di Palo, FQ1
Vegeto, A2
Belli, L1
Corbetta, G1
Tarantino, A3
Civati, G1
Montagnino, G1
Aroldi, A1
Banfi, G1
De Vecchi, A1
Zubani, R1
Berardinelli, L1
Trento, A1
Griffith, BP2
Hardesty, RL2
Kormos, RL1
Thompson, ME2
Bahnson, HT2
Greenberg, A1
Egel, JW1
Bernstein, RL1
Hastillo, A1
Hess, ML1
Puschett, JB1
Myers, BD1
Triolo, G1
Segoloni, GP1
Ferrero, R1
Maritano, M1
Vercellone, A1
Klingmüller, D1
Dieker, P1
Magnussen, H1
Kramer, HJ1
Hall, BM1
Tiller, DJ1
Duggin, GG1
Horvath, JS1
Farnsworth, A1
May, J1
Johnson, JR1
Sheil, AG1
Major, GA1
Moore, PG1
Gardner, SD1
Field, AM1
Coleman, DV1
Hulme, B1
Wagner, A1
Bock, KD1
Bohle, A1
Belzer, FO1
Kountz, SL2
Sraer, JD1
Beaufils, P1
Morel-Maroger, L1
Richet, G1
Kolff, WJ1
Reveillaud, RJ1
Leski, M2
Luke, RG1
Talbert, W1
Siegel, RR1
Holland, N1
Strauch, BS1
Charney, A1
Doctorouff, S1
Kashgarian, M1
Imbasciati, E1
Brancaccio, D1
Rivolta, E1
Lyons, GW1
Lindsay, WG1
McCullough, DL1
Gittes, RF1
Montorsi, W1
Cameron, JS1
Najarian, JS1
Henriksen, AI1
Simmons, RL1
Kjellstrand, CM1
Fuller, T1
Olsen, N1
Block, A1
Cade, J1
Lyons, H1
Pinn, VW1
Cortell, S1
Cohen, JJ1
Harrington, JT1
Striker, GE1
Cutler, RE1
Huang, TW1
Benditt, EP1
Mathew, TH1
Kincaid-Smith, P1
Korz, R1
Volz-Boers, U1
Almgård, LE1
Ljungqvist, A1
Lucas, ZJ1
Palmer, JM1
Payne, R1
Cohn, RB1
Bach, JF2
Dardenne, M1
Vallota, EH1
Forristal, J1
Davis, NC1
West, CD1
Sloth, K1
Thomsen, AC1
Hovland, KR1
Ellis, PP1
Mehls, O1
Schärer, K1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Conversion of Calcineurin-Inhibitors(Tacrolimus to Sirolimus),6-24 Months Post Transplant Prednisone-Free Immunosuppression Regimen: Impact of Incidence of Acute Cellular Rejection,Renal Allograft Function & Lymphocytes Function[NCT00866879]Phase 4275 participants (Actual)Interventional2007-06-30Completed
Genetic Predisposition of Chronic Nephrotoxicity From Calcineurin Inhibitors in Liver Transplant Recipients, Potential Correlation With Urinary Biomarkers[NCT00857844]207 participants (Actual)Observational2007-07-31Completed
BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288]0 participants (Actual)Observational2015-09-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Acute Cellular Rejection

The primary purpose of this research study is to evaluate whether the use of mycophenolate mofetil/Cellcept ® and either tacrolimus/Prograf ® (Group #1) or mycophenolate mofetil/Cellcept ® and sirolimus/Rapamune® (Group #2) impacts the incidence of acute cellular rejection in post-kidney transplant patients. This study will examine whether switching from tacrolimus to sirolimus will better preserve long-term kidney function. (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

InterventionParticipants (Count of Participants)
Control7
Transition to Sirolimus Group31

Percentage of Regulatory T Cells

"Specifically we reported here the percentage of regulatory T cells that were present in the two groups at 24 months post randomization.~With peripheral leukocytes taken at baseline (first visit) prior to randomization and at 6, 12 and 24 Months post-randomization, researchers will also review possible modifications of lymphocytes function and of the lymphocytes subpopulations that might have occurred as a consequence of the switch from tacrolimus to sirolimus (randomization)." (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

Intervention% of Treg Cells (Mean)
Control75
Transition to Sirolimus Group98

Renal Allograft Function Calculated With e-GFR and Proteinuria

Evaluate whether CI conversion (tacrolimus→sirolimus) contributes positively or negatively on the renal allograft function calculated with e-GFR and proteinuria (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

InterventionmL/min (Mean)
Control57.6
Transition to Sirolimus Group58.4

Evaluate if CI Conversion Impacts on Lipid Profile, Incidence of Hypertension, Malignancies, and Opportunistic Infections and Post-transplant DM

In addition to monitoring renal allograft function, evaluation will be conducted on the incidence of acute rejection, patient and graft survival, the impact of CI conversion on the lipid profile, the incidence of hypertension, malignancies, opportunistic infections and post-transplant DM (de novo diabetes mellitus). (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

,
Interventionnumber of incidents (Number)
InfectionsMalignanciesProteinuraHyperlipidemiaNODATBK viremiaBK nephropathyNeutropenia
Control334129315122
Transition to Sirolimus Group8396119228535

Patient and Graft Survival

This study also reviews the impact of the immunosuppressive medications on patient and graft survival. (NCT00866879)
Timeframe: Assessed at 6 Months, 12 Months, 24 Months, months 24 reported

,
Interventionnumber of incidents (Number)
Kidney transplant lossPatient death
Control43
Transition to Sirolimus Group1210

Reviews

7 reviews available for azathioprine and Acute Kidney Injury

ArticleYear
Interventions for renal vasculitis in adults.
    The Cochrane database of systematic reviews, 2020, 01-13, Volume: 1

    Topics: Acute Kidney Injury; Adult; Azathioprine; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppre

2020
Interventions for renal vasculitis in adults.
    The Cochrane database of systematic reviews, 2015, Sep-24, Issue:9

    Topics: Acute Kidney Injury; Adult; Azathioprine; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppre

2015
Role of Pharmacogenomics in Kidney Disease and Injury.
    Advances in chronic kidney disease, 2016, Volume: 23, Issue:2

    Topics: Acute Kidney Injury; Azathioprine; Calcineurin Inhibitors; Cisplatin; Cyclophosphamide; Cytochrome P

2016
Interventions for renal vasculitis in adults.
    The Cochrane database of systematic reviews, 2008, Jul-16, Issue:3

    Topics: Acute Kidney Injury; Adult; Azathioprine; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppre

2008
Hypersensitivity reaction to azathioprine.
    Southern medical journal, 1998, Volume: 91, Issue:5

    Topics: Acute Kidney Injury; Adult; Anaphylaxis; Arthritis, Psoriatic; Azathioprine; Diagnosis, Differential

1998
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Cyclosporine nephrotoxicity.
    Kidney international, 1986, Volume: 30, Issue:6

    Topics: Acute Kidney Injury; Adult; Azathioprine; Creatine; Cyclosporins; Glomerular Filtration Rate; Glomer

1986
Kidney transplantation for patients with diabetes mellitus.
    Transplantation proceedings, 1974, Volume: 6, Issue:4 Suppl 1

    Topics: Acute Kidney Injury; Adult; Antilymphocyte Serum; Azathioprine; Creatinine; Diabetes Complications;

1974

Trials

7 trials available for azathioprine and Acute Kidney Injury

ArticleYear
Nephrotoxic effects of primary immunosuppression with FK-506 and cyclosporine regimens after liver transplantation.
    Mayo Clinic proceedings, 1994, Volume: 69, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Azathioprine; Creatinine; Cyclosporine; Drug Therapy, Combination;

1994
Comparison of OKT3 with ALG for prophylaxis for patients with acute renal failure after cadaveric renal transplantation.
    Transplantation, 1991, Volume: 52, Issue:1

    Topics: Acute Kidney Injury; Adult; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antilym

1991
Immediate post-transplant renal failure: evidence for an immunologic pathogenesis.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Acute Kidney Injury; Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Dru

1989
Mannitol as an indispensable constituent of an intraoperative hydration protocol for the prevention of acute renal failure after renal cadaveric transplantation.
    Transplantation, 1987, Volume: 44, Issue:6

    Topics: Acute Kidney Injury; Azathioprine; Cadaver; Cyclosporins; Glucose; Humans; Intraoperative Care; Kidn

1987
The Milan clinical trial with cyclosporine in cadaveric renal transplantation. A three-year follow-up.
    Transplantation, 1988, Volume: 45, Issue:5

    Topics: Acute Kidney Injury; Adult; Azathioprine; Cyclosporins; Follow-Up Studies; Graft Rejection; Graft Su

1988
A randomized trial comparing triple-drug and double-drug therapy in renal transplantation.
    Transplantation, 1988, Volume: 45, Issue:5

    Topics: Acute Kidney Injury; Azathioprine; Cyclosporins; Dose-Response Relationship, Drug; Drug Therapy, Com

1988
Post-transplant acute renal failure in cadaver renal recipients treated with cyclosporine.
    Kidney international, 1985, Volume: 28, Issue:2

    Topics: Acute Kidney Injury; Antilymphocyte Serum; Azathioprine; Cadaver; Clinical Trials as Topic; Cyclospo

1985

Other Studies

60 other studies available for azathioprine and Acute Kidney Injury

ArticleYear
Predictors of treatment outcomes in lupus nephritis with severe acute kidney injury and requirement of dialytic support.
    Clinical rheumatology, 2023, Volume: 42, Issue:8

    Topics: Acute Kidney Injury; Azathioprine; Humans; Kidney; Lupus Nephritis; Proteinuria; Renal Dialysis; Ret

2023
Quiz Page February 2016: Acute Kidney Injury in a Patient With Granulomatosis With Polyangiitis Receiving Maintenance Immunosuppressive Therapy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2016, Volume: 67, Issue:2

    Topics: Acute Kidney Injury; Azathioprine; Granulomatosis with Polyangiitis; Humans; Immunosuppressive Agent

2016
Acute renal failure in paediatric systemic lupus erythematosus: treatment and outcome.
    Rheumatology (Oxford, England), 2009, Volume: 48, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Area Under Curve; Azathioprine; Child; Child, Preschool; Cyc

2009
Fatal rhabdomyolysis in systemic lupus erythematosus.
    Rheumatology international, 2011, Volume: 31, Issue:9

    Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Antibodies, Antinuclear; Arthritis; Azathioprine;

2011
Quiz page February 2011: acute kidney injury, graft pain, and subtherapeutic levels of tacrolimus.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011, Volume: 57, Issue:2

    Topics: Acute Kidney Injury; Azathioprine; Biopsy; Female; Humans; Immunosuppressive Agents; Kidney; Kidney

2011
Acute graft dysfunction due to pyelonephritis: value and safety of graft biopsy.
    Renal failure, 2003, Volume: 25, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Biopsy; Cyclosporine; Female; Fever; Graft Rej

2003
[FIRST EXPERIENCES IN RENAL TRANSPLANTATION IN HUMANS].
    Gaceta medica de Mexico, 1964, Volume: 94

    Topics: Acute Kidney Injury; Allergy and Immunology; Antineoplastic Agents; Azathioprine; Dactinomycin; Glom

1964
EXPERIENCE WITH 45 RENAL HOMOTRANSPLANTATIONS IN MAN.
    Lancet (London, England), 1965, May-08, Volume: 1, Issue:7393

    Topics: Acute Kidney Injury; Azathioprine; Cobalt Isotopes; Drug Therapy; Immune Tolerance; Immunosuppressiv

1965
The effect of cyclosporine on early graft function in human renal transplantation.
    Transplantation, 1983, Volume: 36, Issue:3

    Topics: Acute Kidney Injury; Azathioprine; Cyclosporins; Graft Survival; Humans; Kidney; Kidney Transplantat

1983
Renal involvement in systemic lupus erythematosus.
    The Medical journal of Australia, 1984, Jun-23, Volume: 140, Issue:13

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Azathioprine; Drug Therapy, Combination; Female; Glome

1984
Acute renal failure in essential mixed cryoglobulinemia: precipitation and reversal by plasma exchange.
    Clinical nephrology, 1984, Volume: 21, Issue:5

    Topics: Acute Kidney Injury; Adult; Azathioprine; Biopsy; Cryoglobulinemia; Humans; Kidney; Male; Paraprotei

1984
[Wegener's granulomatosis as a rare cause for kidney failure].
    Acta medica Austriaca, 1983, Volume: 10, Issue:1

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Azathioprine; Cyclophosphamide; Granulomatosis

1983
Fulminating anti-A autoimmune hemolysis with anuria in a renal transplant recipient: a therapeutic role of plasma exchange.
    Clinical nephrology, 1981, Volume: 16, Issue:4

    Topics: Acute Kidney Injury; Adult; Antilymphocyte Serum; Anuria; Autoimmune Diseases; Azathioprine; Female;

1981
[Acute drug-induced renal failure with severe clinical course].
    Polskie Archiwum Medycyny Wewnetrznej, 1982, Volume: 68, Issue:4

    Topics: Acute Kidney Injury; Adolescent; Anti-Infective Agents; Anticoagulants; Azathioprine; Diuretics; Dru

1982
FK 506 rescue therapy: the rapidity of rejection reversal is related to the subsequent development of CMV disease.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Alanine Transaminase; Azathioprine; Bilirubin; Cyclosp

1993
Nephrotoxicity due to azathioprine.
    The British journal of dermatology, 1993, Volume: 128, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Azathioprine; Humans; Kidney; Male; Nephritis, Interstitial

1993
[Haemodialysis for renal failure in a case of systemic lupus erythematosus (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Jun-13, Volume: 100, Issue:24

    Topics: Acute Kidney Injury; Adult; Antibodies, Antinuclear; Anuria; Azathioprine; Blood Urea Nitrogen; Comp

1975
Renal transplantation in pediatric patients.
    The Journal of urology, 1975, Volume: 113, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Antilymphocyte Serum; Azathioprine; Cadaver; Child; Child, Preschoo

1975
Renal transplantation. Complications in patients with juvenile diabetes.
    Urology, 1975, Volume: 5, Issue:1

    Topics: Acute Kidney Injury; Adult; Azathioprine; Diabetes Mellitus, Type 1; Femoral Vein; Gastrointestinal

1975
Extensive intraglomerular fibrin deposition after renal transplantation: recovery without anticoagulation.
    Canadian Medical Association journal, 1975, Apr-05, Volume: 112, Issue:7

    Topics: Acute Kidney Injury; Azathioprine; Biopsy, Needle; Cadaver; Cyclophosphamide; Fibrin; Graft Rejectio

1975
Renal transplantation in the older age group.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:9

    Topics: Acute Kidney Injury; Age Factors; Aged; Azathioprine; Cadaver; Coronary Disease; Diabetes Complicati

1975
[Amyloidosis in familial mediterranean fever: clinical and renal-biopsy features (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Feb-06, Volume: 101, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adult; Amyloidosis; Azathioprine; Biopsy; Familial Mediterranean Fe

1976
Antilymphocyte globulin with a small dose of cyclosporine A and prednisone as the induction of immunosuppression in renal allograft recipients.
    Archivum immunologiae et therapiae experimentalis, 1992, Volume: 40, Issue:2

    Topics: Acute Disease; Acute Kidney Injury; Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Th

1992
Heart- and heart-lung transplantation in children.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1989, Volume: 3, Issue:3

    Topics: Acute Kidney Injury; Azathioprine; Child; Child, Preschool; Cyclosporins; Drug Therapy, Combination;

1989
Acute renal failure after renal transplantation under various immunosuppressive regimens.
    Transplantation proceedings, 1988, Volume: 20, Issue:5 Suppl 6

    Topics: Acute Kidney Injury; Administration, Oral; Adolescent; Adult; Azathioprine; Cyclosporins; Graft Reje

1988
Does ATN influence renal transplant function negatively?
    Transplantation proceedings, 1988, Volume: 20, Issue:5

    Topics: Acute Kidney Injury; Azathioprine; Cyclosporins; Graft Survival; Humans; Ischemia; Kidney; Kidney Fu

1988
Cardiac transplantation: improved quality of survival with a modified immunosuppressive protocol.
    Circulation, 1987, Volume: 76, Issue:5 Pt 2

    Topics: Actuarial Analysis; Acute Kidney Injury; Antilymphocyte Serum; Azathioprine; Creatine; Drug Administ

1987
Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1987, Volume: 9, Issue:1

    Topics: Acute Kidney Injury; Adult; Azathioprine; beta 2-Microglobulin; Cardiopulmonary Bypass; Cyclosporins

1987
Reduction of the risk of acute tubular necrosis in ciclosporin-treated patients.
    Contributions to nephrology, 1986, Volume: 51

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Creatinine; Cyclosporins; Female; Graft Reject

1986
[Reversible acute kidney failure in Wegener's granulomatosis].
    Der Internist, 1985, Volume: 26, Issue:6

    Topics: Acute Kidney Injury; Azathioprine; Combined Modality Therapy; Cyclophosphamide; Drug Therapy, Combin

1985
Profound circulatory collapse due to azathioprine.
    Journal of the Royal Society of Medicine, 1985, Volume: 78, Issue:12

    Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Jaundice; Middle Aged; Pan

1985
New human papovavirus (B.K.) isolated from urine after renal transplantation.
    Lancet (London, England), 1971, Jun-19, Volume: 1, Issue:7712

    Topics: Acute Kidney Injury; Adult; Antibodies; Azathioprine; Chronic Disease; Complement Fixation Tests; He

1971
Azathioprine treatment in primary sclerosing cholangitis.
    Lancet (London, England), 1971, Sep-18, Volume: 2, Issue:7725

    Topics: Acute Kidney Injury; Autopsy; Azathioprine; Bilirubin; Cholangitis; Humans; Liver Abscess; Male; Mid

1971
[Peracute primary malignant nephrosclerosis with irreversible kidney failure and malignant hypertension following ovulation inhibitors].
    Deutsche medizinische Wochenschrift (1946), 1973, Apr-13, Volume: 98, Issue:15

    Topics: Acute Kidney Injury; Adult; Azathioprine; Biopsy; Chlormadinone Acetate; Contraceptives, Oral; Drug

1973
The role of clinical transplantation in patients with end-stage renal disease.
    Transplantation proceedings, 1973, Volume: 5, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Child; Child, Preschool;

1973
Vascular nephropathies with acute renal failure.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Acute Kidney Injury; Antihypertensive Agents; Azathioprine; Biopsy; Capillaries; Heparin; Humans; Hy

1973
[Hemodialysis and kidney transplantation].
    Munchener medizinische Wochenschrift (1950), 1965, Sep-03, Volume: 107, Issue:36

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Agranulocytosis; Azathioprine; Dactinomycin; Humans; H

1965
[Indications and results of renal transplantation].
    La Presse medicale, 1970, Apr-04, Volume: 78, Issue:17

    Topics: Acute Kidney Injury; Adult; Antibodies; Azathioprine; Blood Group Antigens; Cadaver; Child; Culture

1970
Heparin treatment for post-partum renal failure with microangiopathic haemolytic anaemia.
    Lancet (London, England), 1970, Oct-10, Volume: 2, Issue:7676

    Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Azathioprine; Beta-Globulins; Biopsy; Female; Fibrin;

1970
Clinicopathologic conference. Renal insufficiency following renal transplant. Résumé of case.
    Mayo Clinic proceedings, 1969, Volume: 44, Issue:1

    Topics: Acute Kidney Injury; Adult; Azathioprine; Cytomegalovirus Infections; Diagnosis, Differential; Gastr

1969
Goodpasture syndrome with recovery after renal failure.
    JAMA, 1974, Jul-22, Volume: 229, Issue:4

    Topics: Acute Kidney Injury; Anti-Glomerular Basement Membrane Disease; Azathioprine; Biopsy; Humans; Kidney

1974
Acute renal failure in systemic lupus erythematosus.
    British medical journal, 1974, Sep-21, Volume: 3, Issue:5933

    Topics: Acute Kidney Injury; Adult; Azathioprine; Biopsy; Creatinine; Cyclophosphamide; Female; Furosemide;

1974
Renal transplantation in a patient with Wegener's granulomatosis.
    American journal of surgery, 1972, Volume: 124, Issue:1

    Topics: Acute Kidney Injury; Adult; Animals; Azathioprine; Biopsy; Globulins; Granulomatosis with Polyangiit

1972
Successful renal transplantation after forty-five hours of extracorporeal perfusion.
    Urology, 1973, Volume: 2, Issue:6

    Topics: Acute Kidney Injury; Azathioprine; Biopsy; Cadaver; Cold Temperature; Drug Hypersensitivity; Graft R

1973
[The kidney transplant].
    Minerva medica, 1974, Jan-31, Volume: 65, Issue:7

    Topics: Acute Kidney Injury; Animals; Antilymphocyte Serum; Azathioprine; Graft Rejection; Humans; Kidney Di

1974
Are anticoagulants beneficial in the treatment of rapidly progressive glomerulonephritis?
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Acute Kidney Injury; Adult; Anticoagulants; Azathioprine; Biopsy; Cyclophosphamide; Dipyridamole; Fe

1973
Wegener's granulomatosis. Treatment with heparin in addition to azathioprine and corticosteroids.
    Nephron, 1972, Volume: 9, Issue:4

    Topics: Acute Kidney Injury; Azathioprine; Biopsy; Granulomatosis with Polyangiitis; Heparin; Humans; Kidney

1972
Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.
    The New England journal of medicine, 1973, Jan-18, Volume: 288, Issue:3

    Topics: Acute Kidney Injury; Adult; Azathioprine; Chlorothiazide; Drug Hypersensitivity; Eosinophils; Female

1973
Renal failure, glomerulonephritis and glomerular epithelial cell hyperplasia.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Epithelial Cell

1973
Severe fibrin and crescent glomerulonephritis: clinical and morphological aspects of 33 patients.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anticoagulants; Australia; Azathioprine; Biopsy; Creat

1973
[Acute renal failure after massive myolysis in pseudomyopathic polymyositis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, May-17, Volume: 99, Issue:20

    Topics: Acute Kidney Injury; Adult; Azathioprine; Biopsy; Creatine Kinase; Electromyography; Female; Humans;

1974
The function of the drug-modified canine renal allograft.
    Scandinavian journal of urology and nephrology, 1968, Volume: 2, Issue:3

    Topics: Acute Kidney Injury; Animals; Azathioprine; Dogs; Glomerular Filtration Rate; Histocompatibility; Im

1968
Renal allotransplantation in humans. I. Systemic immunosuppressive therapy.
    Archives of surgery (Chicago, Ill. : 1960), 1970, Volume: 100, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Child; Dactinomycin; Female; Heparin; Histocom

1970
[Renal transplantation crisis].
    La Presse medicale, 1970, Apr-04, Volume: 78, Issue:17

    Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Azathioprine; Female; Histocompatibility; Humans; Immu

1970
Renal transplantation in infants and small children.
    Transplantation proceedings, 1971, Volume: 3, Issue:1

    Topics: Acute Kidney Injury; Age Factors; Antilymphocyte Serum; Azathioprine; Cadaver; Child; Child, Prescho

1971
The metabolism of azathioprine in renal failure.
    Transplantation, 1971, Volume: 12, Issue:4

    Topics: Acute Kidney Injury; Azathioprine; Bone Marrow Diseases; Hemagglutination Tests; Humans; Immunosuppr

1971
The C3 nephritic factor and membranoproliferative nephritis: correlation of serum levels of the nephritic factor with C3 levels, with therapy, and with progression of the disease.
    The Journal of pediatrics, 1972, Volume: 80, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Azathioprine; Child; Child, Preschool; Complement System Proteins;

1972
Acute renal insufficiency during treatment with azathioprine.
    Acta medica Scandinavica, 1971, Volume: 189, Issue:3

    Topics: Acute Kidney Injury; Administration, Oral; Azathioprine; Biopsy; Drug Hypersensitivity; Glomerular F

1971
Ocular changes in renal transplant patients.
    American journal of ophthalmology, 1967, Volume: 63, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Azathioprine; Cataract; Child; Epinephrine; Female; Glaucoma

1967
[Familial nephrotic syndrome].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adrenal Cortex Hormones; Age Factors; Azathioprine; Biopsy; Child;

1970