azathioprine has been researched along with Acute Hypercapnic Respiratory Failure in 22 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 7.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "Azathioprine is an established immunosuppressive agent in the treatment of myasthenia gravis." | 3.69 | [Myasthenic crisis caused by azathioprine-induced fever]. ( George, A; Nau, R; Tumani, H, 1997) |
| "Extended diagnostic measures revealed interstitial lung disease (ILD), polyserositis, polyarthritis and myopathy." | 1.51 | [Progressive respiratory failure and weakness in a 61-year-old woman]. ( Mahmud, M; Schnoor, U; Steinmetz, OM, 2019) |
| "We present 4 patients with CIDP who required respiratory assistance and mechanical ventilation." | 1.33 | Chronic inflammatory demyelinating polyneuropathy and respiratory failure. ( Henderson, RD; Sandroni, P; Wijdicks, EF, 2005) |
| "A patient developed respiratory failure after surgical removal of a recurrent thymoma, which necessitated removal of part of the diaphragm." | 1.28 | Unsuspected myasthenia gravis presenting as respiratory failure. ( Green, M; Laroche, C; Mier, A, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahmud, M | 1 |
| Schnoor, U | 1 |
| Steinmetz, OM | 1 |
| Cabral, DA | 1 |
| Canter, DL | 1 |
| Muscal, E | 1 |
| Nanda, K | 1 |
| Wahezi, DM | 1 |
| Spalding, SJ | 1 |
| Twilt, M | 1 |
| Benseler, SM | 1 |
| Campillo, S | 1 |
| Charuvanij, S | 1 |
| Dancey, P | 1 |
| Eberhard, BA | 1 |
| Elder, ME | 1 |
| Hersh, A | 1 |
| Higgins, GC | 1 |
| Huber, AM | 1 |
| Khubchandani, R | 1 |
| Kim, S | 1 |
| Klein-Gitelman, M | 1 |
| Kostik, MM | 1 |
| Lawson, EF | 1 |
| Lee, T | 1 |
| Lubieniecka, JM | 1 |
| McCurdy, D | 1 |
| Moorthy, LN | 1 |
| Morishita, KA | 1 |
| Nielsen, SM | 1 |
| O'Neil, KM | 1 |
| Reiff, A | 1 |
| Ristic, G | 1 |
| Robinson, AB | 1 |
| Sarmiento, A | 1 |
| Shenoi, S | 1 |
| Toth, MB | 1 |
| Van Mater, HA | 1 |
| Wagner-Weiner, L | 1 |
| Weiss, JE | 1 |
| White, AJ | 1 |
| Yeung, RS | 1 |
| Hernández Pérez, JM | 1 |
| Acosta Fernández, O | 1 |
| Patel, HC | 1 |
| Lauder, NN | 1 |
| Griese, M | 1 |
| Ripper, J | 1 |
| Sibbersen, A | 1 |
| Lohse, P | 2 |
| Brasch, F | 1 |
| Schams, A | 1 |
| Pamir, A | 1 |
| Schaub, B | 1 |
| Muensterer, OJ | 1 |
| Schön, C | 1 |
| Glöckner-Pagel, J | 1 |
| Nicolai, T | 1 |
| Reiter, K | 1 |
| Hector, A | 1 |
| Spoon, KC | 1 |
| Ramar, K | 1 |
| Ishida, T | 1 |
| Kotani, T | 1 |
| Takeuchi, T | 1 |
| Makino, S | 1 |
| Henderson, RD | 1 |
| Sandroni, P | 1 |
| Wijdicks, EF | 1 |
| Churg, A | 1 |
| Müller, NL | 1 |
| Silva, CI | 1 |
| Wright, JL | 1 |
| Theobald, I | 1 |
| Limberg, B | 1 |
| Magener, A | 1 |
| Kauffmann, GW | 1 |
| Tumani, H | 1 |
| George, A | 1 |
| Nau, R | 1 |
| Stamenkovic, SA | 1 |
| Alphonso, N | 1 |
| Rice, P | 1 |
| Madden, BP | 1 |
| Cohen, JM | 1 |
| Miller, A | 1 |
| Spiera, H | 1 |
| Vallet, B | 1 |
| Fourrier, F | 1 |
| Hurtevent, JF | 1 |
| Parent, M | 1 |
| Chopin, C | 1 |
| Mier, A | 1 |
| Laroche, C | 1 |
| Green, M | 1 |
| Kingston, WJ | 1 |
| Moxley, RT | 1 |
| Wildevuur, CR | 1 |
| Benfield, JR | 1 |
| Kreuzer, W | 1 |
| Keiler, A | 1 |
| Salem, G | 1 |
| Göber, I | 1 |
| Radaszkiewicz, T | 1 |
| Mathews, JD | 1 |
| Buckley, JD | 1 |
| Gledhill, VX | 1 |
| Kjellstrand, CM | 1 |
| Simmons, RL | 1 |
| Uranga, VM | 1 |
| Buselmeier, TJ | 1 |
| Najarian, JS | 1 |
| Fuller, T | 1 |
| Olsen, N | 1 |
| Block, A | 1 |
| Cade, J | 1 |
| Haas, W | 1 |
| Münzenmaier, R | 1 |
| Loewe, KR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Randomized Controlled Trial[NCT05674994] | Phase 3 | 110 participants (Anticipated) | Interventional | 2023-10-26 | Recruiting | ||
| Cyclophosphamide Added to Corticosteroid in the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: a Placebo-controlled Randomized Trial[NCT02460588] | Phase 3 | 120 participants (Actual) | Interventional | 2015-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for azathioprine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Treatment of muscular dystrophies and inflammatory myopathies.
Topics: Azathioprine; Clinical Trials as Topic; Dermatomyositis; Humans; Muscular Dystrophies; Myositis; Myo | 1986 |
A review of 23 human lung transplantations by 20 surgeons.
Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Dactinomycin; Female; Histocompatibility Test | 1970 |
1 trial available for azathioprine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
Treatment of muscular dystrophies and inflammatory myopathies.
Topics: Azathioprine; Clinical Trials as Topic; Dermatomyositis; Humans; Muscular Dystrophies; Myositis; Myo | 1986 |
20 other studies available for azathioprine and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
[Progressive respiratory failure and weakness in a 61-year-old woman].
Topics: Amino Acyl-tRNA Synthetases; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Combined Modalit | 2019 |
Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study.
Topics: Adolescent; Adrenal Cortex Hormones; Age Distribution; Antibodies, Antineutrophil Cytoplasmic; Asia; | 2016 |
[Lung disease secondary to morphea en coup de sabre, a form of localized scleroderma].
Topics: Adrenal Cortex Hormones; Adult; Autoantibodies; Azathioprine; Drug Therapy, Combination; Facial Hemi | 2009 |
The antisynthetase syndrome.
Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Azathioprine; Cryptogenic Organizing Pneum | 2011 |
Long-term follow-up and treatment of congenital alveolar proteinosis.
Topics: Adrenal Cortex Hormones; Azathioprine; Bronchoalveolar Lavage; Child; Female; Granulocyte-Macrophage | 2011 |
Unexplained hypoxemia.
Topics: Ascorbic Acid; Azathioprine; Blood Gas Analysis; Dapsone; Female; Follow-Up Studies; Humans; Hyperca | 2011 |
Pulmonary toxicity after initiation of azathioprine for treatment of interstitial pneumonia in a patient with rheumatoid arthritis.
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Dyspnea; Humans; Lung Diseases, Int | 2012 |
Chronic inflammatory demyelinating polyneuropathy and respiratory failure.
Topics: Aged; Azathioprine; Biopsy; Coma; Cyclophosphamide; Electromyography; Female; Follow-Up Studies; Hum | 2005 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
Acute exacerbation (acute lung injury of unknown cause) in UIP and other forms of fibrotic interstitial pneumonias.
Topics: Adult; Aged; Alveolitis, Extrinsic Allergic; Azathioprine; Biopsy; Cyclophosphamide; Disease Progres | 2007 |
[Fulminant, fatal respiratory insufficiency in long-term immunosuppression after kidney transplantation].
Topics: Adult; Azathioprine; Fatal Outcome; Female; Humans; Immunologic Deficiency Syndromes; Kidney Transpl | 1995 |
[Myasthenic crisis caused by azathioprine-induced fever].
Topics: Aged; Azathioprine; Critical Care; Drug Hypersensitivity; Drug Therapy, Combination; Fever; Humans; | 1997 |
Recurrence of hepatitis B after single lung transplantation.
Topics: Adult; Azathioprine; Female; Hepatitis B Antibodies; Hepatitis B, Chronic; Humans; Immunosuppression | 1999 |
Interstitial pneumonitis complicating rheumatoid arthritis. Sustained remission with azathioprine therapy.
Topics: Arthritis, Rheumatoid; Azathioprine; Female; Humans; Middle Aged; Pneumonia; Pulmonary Fibrosis; Res | 1977 |
Myasthenia gravis and steroid-induced myopathy of the respiratory muscles.
Topics: Adrenal Cortex Hormones; Adult; Atrophy; Azathioprine; Electromyography; Female; Humans; Lung Volume | 1992 |
Unsuspected myasthenia gravis presenting as respiratory failure.
Topics: Azathioprine; Humans; Male; Middle Aged; Myasthenia Gravis; Prednisolone; Respiratory Insufficiency | 1990 |
[Results following canine pulmonary transplantation (author's transl)].
Topics: Animals; Azathioprine; Bronchospirometry; Dogs; Graft Rejection; Hemodynamics; Immunosuppression The | 1974 |
Pattern recognition in medicine--a place for the use of principal component analysis and factor analysis.
Topics: Azathioprine; Body Height; Body Weight; Child; Computers; Cyclophosphamide; Diagnosis, Differential; | 1974 |
Acute fulminant Wegener granulomatosis. Therapy with immunosuppression, hemodialysis, and renal transplantation.
Topics: Acute Disease; Adult; Antilymphocyte Serum; Azathioprine; Fluorescent Antibody Technique; Granulomat | 1974 |
Wegener's granulomatosis. Treatment with heparin in addition to azathioprine and corticosteroids.
Topics: Acute Kidney Injury; Azathioprine; Biopsy; Granulomatosis with Polyangiitis; Heparin; Humans; Kidney | 1972 |
[Nitrofurantoin-induced chronic pulmonary fibrosis (author's transl)].
Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Chronic Disease; Fever; Humans; Male; Nitrofurantoin; P | 1973 |