azathioprine has been researched along with Acute Febrile Neutrophilic Dermatosis in 35 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is a commonly used immunosuppressive therapy that has been implicated in a number of cutaneous and systemic inflammatory reactions." | 5.91 | Azathioprine hypersensitivity syndrome manifesting as subcutaneous Sweet syndrome and acute pancreatitis. ( Harp, J; Magro, C; Tee, MW; Thomas, JL, 2023) |
| " We report the case of a 50-year-old patient with indeterminate colitis, presenting with a febrile diffuse papulopustular and necrotizing skin eruption that healed with significant scarring and appeared 14 days after onset of treatment with azathioprine." | 4.91 | Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature. ( Contassot, E; Frei, P; French, LE; Imhof, L; Kamarachev, J; Kolios, A; Meier, B; Navarini, AA; Rogler, G, 2015) |
| "A 52-year-old man presented with high-grade fever, headache and painful vesicular skin rash involving the upper trunk and upper extremities, 8 days after initiation of chemotherapy with azathioprine (50 mg/day), which had been prescribed for acral vitiligo." | 3.83 | Azathioprine-induced bullous Sweet's syndrome: a rare association. ( Bar, C; Biswas, SN; Chakraborty, PP; Gantait, K, 2016) |
| "An 81-year-old woman with Crohn disease presented with fever and an acute eruption of plaques on her extremities within 2 weeks of starting treatment with azathioprine." | 3.79 | Neutrophilic dermatosis after azathioprine exposure. ( Choi, JN; Cyrus, N; Ko, CJ; Mason, AR; Stavert, R, 2013) |
| "Established associations exist between Sweet's syndrome and some medications; however, to date links to azathioprine are tentative." | 2.55 | Azathioprine-induced Sweet's syndrome: A case series and review of the literature. ( Ibbetson, J; McNally, A; Sidhu, S, 2017) |
| "Azathioprine-induced Sweet's syndrome (SS) is rare and usually overlooked because it can mimic disease exacerbation and sepsis." | 2.49 | Azathioprine-induced Sweet's syndrome and published work review. ( Chaowattanapanit, S; Choonhakarn, C, 2013) |
| "Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain drugs." | 2.46 | EPONYM. Sweet syndrome. ( Choe, YH; Kim, MJ, 2010) |
| "Ulcerative colitis is an inflammatory bowel disease often associated with extra-intestinal manifestations, such as dermatological disorders." | 2.42 | Diffuse febrile dermatosis in a patient with active ulcerative colitis under treatment with steroids and azathioprine: a case of Sweet's syndrome. Case report and review of literature. ( Amantea, A; Consolazio, A; Crispino, P; Di Palma, V; Iacopini, F; Paoluzi, OA; Paoluzi, P; Pica, R; Rivera, M, 2004) |
| "Azathioprine (AZA) is a commonly used immunosuppressive therapy that has been implicated in a number of cutaneous and systemic inflammatory reactions." | 1.91 | Azathioprine hypersensitivity syndrome manifesting as subcutaneous Sweet syndrome and acute pancreatitis. ( Harp, J; Magro, C; Tee, MW; Thomas, JL, 2023) |
| "Sweet syndrome is a rare complication of azathioprine treatment with unelucidated clinical features." | 1.91 | Clinical characteristics, diagnosis and management of Sweet syndrome induced by azathioprine. ( Fan, Z; He, Y; Li, Z; Sun, W; Wang, C; Ye, C, 2023) |
| "Here, we report a rare case of Sweet's syndrome induced by azathioprine in a patient with Crohn's disease." | 1.42 | A Rare Case of Azathioprine-Induced Sweet's Syndrome in a Patient with Crohn's Disease. ( Aounallah, A; Ben Salem, C; Fathallah, N; Hmouda, H; Larif, S; Sakhri, J; Salem, CB; Slim, R, 2015) |
| "Histiocytoid Sweet syndrome (HSS) is a rare histologic variation of Sweet syndrome (SS) predominantly exhibiting mononuclear histiocytoid cells instead of neutrophils." | 1.42 | Histiocytoid Sweet syndrome treated with azathioprine: a case report. ( Lee, N; Miller, J; Sami, N, 2015) |
| "We describe a pediatric case of Sweet syndrome presenting 10 days after treatment with azathioprine." | 1.37 | Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis. ( Choe, YH; Jang, KT; Kim, MJ, 2011) |
| "Sweet syndrome is a reactive, sterile, pustular dermatosis that occurs in association with infection, malignancy, or connective tissue disease or in response to the use of certain medications." | 1.35 | Sweet syndrome as a manifestation of azathioprine hypersensitivity. ( Brunner, KL; El-Azhary, RA; Gibson, LE, 2008) |
| "The azathioprine was temporarily withheld and oral prednisolone was increased as it was thought that the neutrophilic dermatosis was associated with the underlying ulcerative colitis." | 1.35 | Azathioprine hypersensitivity presenting as a neutrophilic dermatosis in a man with ulcerative colitis. ( Thom, G; Yiasemides, E, 2009) |
| "A 47-year-old man with a history of ulcerative colitis on prednisone and azathioprine was admitted to the hospital with a four-day history of fever, skin rash, arthralgias and leukocytosis." | 1.35 | Ulcerative colitis and Sweet's syndrome: a case report and review of the literature. ( Ali, M; Duerksen, DR, 2008) |
| "Among the rare cases of Sweet syndrome associated to a systemic inflammatory response syndrome that have been described there have not been any fatal cases as occurred with our patient." | 1.34 | [Fatal Sweet syndrome associated to chronic idiopathic systemic inflammatory response syndrome]. ( Almagro, M; del Pozo, J; Fonseca, E; Malmierca, NM; Martín, CG; Martínez, W; Yebra-Pimentel, MT, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 10 (28.57) | 29.6817 |
| 2010's | 19 (54.29) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, JL | 1 |
| Tee, MW | 1 |
| Harp, J | 1 |
| Magro, C | 1 |
| Fan, Z | 1 |
| He, Y | 1 |
| Sun, W | 1 |
| Li, Z | 1 |
| Ye, C | 1 |
| Wang, C | 1 |
| Kearney, N | 1 |
| Harnett, C | 1 |
| Keohane, J | 1 |
| Thorne, J | 1 |
| Feighery, C | 1 |
| Collins, S | 1 |
| Miranda, E | 1 |
| Meza, R | 1 |
| Kolbach, M | 1 |
| Torres, J | 1 |
| Harris, PR | 1 |
| McKenzie, T | 1 |
| Dheda, S | 1 |
| Mantha, M | 1 |
| Larsen, C | 1 |
| Moreno Márquez, C | 1 |
| Maldonado Pérez, B | 1 |
| Castro Laria, L | 1 |
| Cyrus, N | 1 |
| Stavert, R | 1 |
| Mason, AR | 1 |
| Ko, CJ | 1 |
| Choi, JN | 1 |
| Grelle, JL | 1 |
| Halloush, RA | 1 |
| Khasawneh, FA | 1 |
| Schmutz, JL | 1 |
| Imhof, L | 1 |
| Meier, B | 1 |
| Frei, P | 1 |
| Kamarachev, J | 1 |
| Rogler, G | 1 |
| Kolios, A | 1 |
| Navarini, AA | 1 |
| Contassot, E | 1 |
| French, LE | 1 |
| Ben Salem, C | 1 |
| Salem, CB | 1 |
| Larif, S | 1 |
| Fathallah, N | 1 |
| Slim, R | 1 |
| Aounallah, A | 1 |
| Sakhri, J | 1 |
| Hmouda, H | 1 |
| McNally, A | 1 |
| Ibbetson, J | 1 |
| Sidhu, S | 1 |
| Miller, J | 1 |
| Lee, N | 1 |
| Sami, N | 1 |
| Biswas, SN | 1 |
| Chakraborty, PP | 1 |
| Gantait, K | 1 |
| Bar, C | 1 |
| Cheraghi, N | 1 |
| Yasuda, M | 1 |
| Deng, A | 1 |
| Mailhot, J | 1 |
| Willis, DF | 1 |
| Chacko, B | 1 |
| Tien, V | 1 |
| Jones, AD | 1 |
| Aronowitz, PB | 1 |
| Treton, X | 1 |
| Joly, F | 1 |
| Alves, A | 1 |
| Panis, Y | 1 |
| Bouhnik, Y | 1 |
| El-Azhary, RA | 1 |
| Brunner, KL | 1 |
| Gibson, LE | 1 |
| Décisier, M | 1 |
| Duhalde, V | 1 |
| Faure, P | 1 |
| Ammoury, A | 1 |
| Gony, M | 1 |
| Moreau, J | 1 |
| Montastruc, JL | 1 |
| Bagheri, H | 1 |
| Yiasemides, E | 1 |
| Thom, G | 1 |
| Kim, MJ | 2 |
| Choe, YH | 2 |
| Bidinger, JJ | 1 |
| Sky, K | 1 |
| Battafarano, DF | 1 |
| Henning, JS | 1 |
| Jang, KT | 1 |
| Flores Martín, IM | 1 |
| López-Sáez, MP | 1 |
| Brugaletta Matheus, DC | 1 |
| Acosta Ruiz, G | 1 |
| López, JD | 1 |
| Pagán Alemán, JA | 1 |
| Hurtado-Garcia, R | 2 |
| Escribano-Stablé, JC | 1 |
| Pascual, Jc | 1 |
| Devesa, P | 1 |
| Matarredona, J | 1 |
| Turow, A | 1 |
| Yong, TY | 1 |
| Fok, JS | 1 |
| Li, JY | 1 |
| Choonhakarn, C | 1 |
| Chaowattanapanit, S | 1 |
| Matzkies, FG | 1 |
| Manger, B | 1 |
| Schmitt-Haendle, M | 1 |
| Nagel, T | 1 |
| Kraetsch, HG | 1 |
| Kalden, JR | 1 |
| Schulze-Koops, H | 1 |
| Paoluzi, OA | 1 |
| Crispino, P | 1 |
| Amantea, A | 1 |
| Pica, R | 1 |
| Iacopini, F | 1 |
| Consolazio, A | 1 |
| Di Palma, V | 1 |
| Rivera, M | 1 |
| Paoluzi, P | 1 |
| del Pozo, J | 2 |
| Martínez, W | 2 |
| Carro, E | 1 |
| Arévalo, MP | 1 |
| Rodríguez-Lozano, J | 1 |
| Fonseca, E | 2 |
| Malmierca, NM | 1 |
| Yebra-Pimentel, MT | 1 |
| Almagro, M | 1 |
| Martín, CG | 1 |
| Castro-Fernández, M | 1 |
| Sánchez-Muñoz, D | 1 |
| Ruíz-Granados, E | 1 |
| Merchante, N | 1 |
| Corzo, J | 1 |
| Ali, M | 1 |
| Duerksen, DR | 1 |
| Burrows, NP | 1 |
6 reviews available for azathioprine and Acute Febrile Neutrophilic Dermatosis
| Article | Year |
|---|---|
Severe Sweet's Syndrome with Elevated Cutaneous Interleukin-1β after Azathioprine Exposure: Case Report and Review of the Literature.
Topics: Anti-Inflammatory Agents; Azathioprine; Colitis; Drug Eruptions; Humans; Immunosuppressive Agents; I | 2015 |
Azathioprine-induced Sweet's syndrome: A case series and review of the literature.
Topics: Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Sweet Syndrome | 2017 |
EPONYM. Sweet syndrome.
Topics: Adult; Azathioprine; Child; Connective Tissue Diseases; Erythema; Fever; Granulocyte Colony-Stimulat | 2010 |
The cutaneous and systemic manifestations of azathioprine hypersensitivity syndrome.
Topics: Adult; Aged; Azathioprine; Biopsy, Needle; Dose-Response Relationship, Drug; Drug Administration Sch | 2011 |
Azathioprine-induced Sweet's syndrome and published work review.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Azathioprine; Child; Female; Humans; Immun | 2013 |
Diffuse febrile dermatosis in a patient with active ulcerative colitis under treatment with steroids and azathioprine: a case of Sweet's syndrome. Case report and review of literature.
Topics: Azathioprine; Colitis, Ulcerative; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Middle A | 2004 |
29 other studies available for azathioprine and Acute Febrile Neutrophilic Dermatosis
| Article | Year |
|---|---|
Azathioprine hypersensitivity syndrome manifesting as subcutaneous Sweet syndrome and acute pancreatitis.
Topics: Acute Disease; Azathioprine; Drug Hypersensitivity Syndrome; Humans; Immunosuppressive Agents; Pancr | 2023 |
Clinical characteristics, diagnosis and management of Sweet syndrome induced by azathioprine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Humans; Male; Middle Aged; Prognosi | 2023 |
Acute penoscrotal and soft tissue swelling with cutaneous plaques.
Topics: Azathioprine; Colitis, Ulcerative; Humans; Immunosuppressive Agents; Male; Penis; Prednisolone; Scro | 2020 |
Sweet Syndrome in Pediatric Active Ulcerative Colitis.
Topics: Adalimumab; Antirheumatic Agents; Azathioprine; Child; Colitis, Ulcerative; Colonoscopy; Drug Substi | 2021 |
Azathioprine hypersensitivity syndrome: report of two cases.
Topics: Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Drug Hypersensitivity S | 2021 |
Infliximab as Rescue Treatment in Sweet's Syndrome Related to Corticodependent Ulcerative Colitis.
Topics: Adult; Azathioprine; Biopsy; Colitis, Ulcerative; Dermatologic Agents; Diagnosis, Differential; Drug | 2018 |
Neutrophilic dermatosis after azathioprine exposure.
Topics: Aged, 80 and over; Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Eruptions; Female; Hum | 2013 |
Azathioprine-induced acute febrile neutrophilic dermatosis (Sweet's syndrome).
Topics: Aged; Azathioprine; Humans; Immunosuppressive Agents; Male; Sweet Syndrome | 2013 |
[Neutrophilic eccrine hidradenitis and azathioprine hypersensitivity syndrome].
Topics: Azathioprine; Crohn Disease; Diagnosis, Differential; Drug Hypersensitivity; Hidradenitis; Humans; I | 2014 |
A Rare Case of Azathioprine-Induced Sweet's Syndrome in a Patient with Crohn's Disease.
Topics: Anti-Inflammatory Agents; Azathioprine; Biopsy; Crohn Disease; Gastrointestinal Agents; Humans; Male | 2015 |
Histiocytoid Sweet syndrome treated with azathioprine: a case report.
Topics: Azathioprine; Biopsy, Needle; Female; Follow-Up Studies; Histiocytes; Histiocytosis; Humans; Immunoh | 2015 |
Azathioprine-induced bullous Sweet's syndrome: a rare association.
Topics: Azathioprine; Blister; Exanthema; Fever; Headache; Humans; Immunosuppressive Agents; Male; Middle Ag | 2016 |
Azathioprine hypersensitivity presenting as neutrophilic dermatosis and erythema nodosum.
Topics: Azathioprine; Crohn Disease; Drug Hypersensitivity; Erythema Nodosum; Humans; Immunosuppressive Agen | 2016 |
Rash and fever in a man with granulomatosis with polyangiitis (Wegener's).
Topics: Azathioprine; Biopsy; Drug Eruptions; Exanthema; Fever; Glucocorticoids; Granulomatosis with Polyang | 2016 |
Drug-Induced Sweet's Syndrome.
Topics: Aged; Azathioprine; Biopsy; Colitis, Ulcerative; Humans; Immunosuppressive Agents; Male; Sweet Syndr | 2017 |
Azathioprine-induced Sweet's syndrome in Crohn's disease.
Topics: Azathioprine; Crohn Disease; Humans; Immunosuppressive Agents; Male; Middle Aged; Sweet Syndrome | 2008 |
Sweet syndrome as a manifestation of azathioprine hypersensitivity.
Topics: Adult; Aged; Azathioprine; Colitis, Ulcerative; Crohn Disease; Drug Hypersensitivity; Humans; Immuno | 2008 |
Rapid-onset febrile dermatosis.
Topics: Azathioprine; Colitis, Ulcerative; Drug Eruptions; Humans; Immunosuppressive Agents; Male; Middle Ag | 2009 |
Azathioprine hypersensitivity presenting as a neutrophilic dermatosis in a man with ulcerative colitis.
Topics: Azathioprine; Colitis, Ulcerative; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppres | 2009 |
Azathioprine hypersensitivity presenting as sweet syndrome in a child with ulcerative colitis.
Topics: Azathioprine; Child; Colitis, Ulcerative; Drug Hypersensitivity; Female; Humans; Immunosuppressive A | 2011 |
Azathioprine-induced Sweet's syndrome.
Topics: Aged; Antirheumatic Agents; Azathioprine; Humans; Male; Sweet Syndrome | 2012 |
Neutrophilic dermatosis caused by azathioprine hypersensitivity.
Topics: Adult; Azathioprine; Drug Eruptions; Female; Hand Dermatoses; Humans; Immunosuppressive Agents; Myas | 2012 |
Azathioprine hypersensitivity presenting as cardiogenic shock and Sweet's syndrome in a patient with microscopic polyangiitis.
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Drug Hypersensitivity; Female; Humans; I | 2012 |
Severe septicaemia in a patient with polychondritis and Sweet's syndrome after initiation of treatment with infliximab.
Topics: Antibodies, Monoclonal; Azathioprine; Diabetes Mellitus, Type 1; Fatal Outcome; Humans; Immunosuppre | 2003 |
A case of Sweet's syndrome and pemphigus vulgaris.
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Diagnosis, Differential; Drug Therapy, Combination; Fe | 2004 |
[Fatal Sweet syndrome associated to chronic idiopathic systemic inflammatory response syndrome].
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Biopsy; Chronic Disease; Colchicine; Fatal Outcome; Fe | 2007 |
Coexistence of pyoderma gangrenosum and Sweet's syndrome in a patient with ulcerative colitis.
Topics: Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Dermatologic Agents; Glucocorticoids; Hum | 2007 |
Ulcerative colitis and Sweet's syndrome: a case report and review of the literature.
Topics: Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Comorbidity; Humans; Immunosuppressive | 2008 |
Sweet's syndrome in association with Crohn's disease.
Topics: Azathioprine; Crohn Disease; Female; Humans; Middle Aged; Sweet Syndrome | 1995 |