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azathioprine and Actinic Reticuloid Syndrome

azathioprine has been researched along with Actinic Reticuloid Syndrome in 23 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"Oral azathioprine therapy is an effective and usually well tolerated treatment in chronic actinic dermatitis."2.66Azathioprine treatment in chronic actinic dermatitis: a double-blind controlled trial with monitoring of exposure to ultraviolet radiation. ( Hawk, JL; Maurice, PD; Morris, RW; Murphy, GM; Norris, PG, 1989)
"A 36-year-old woman with systemic lupus erythematosus was admitted to our hospital with malaise, myalgia, dysphagia, fever, preserved muscle strength, leukocytosis (15,600 cells), and increased creatine kinase of 1,358 IU/L that reached 75,000 IU/L in few days."1.37Fatal rhabdomyolysis in systemic lupus erythematosus. ( Bonfa, E; da Mota, LM; de Carvalho, JF, 2011)
"Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors."1.31Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002)
"Fourteen patients with severe unremitting chronic actinic dermatitis were treated with oral azathioprine in a dosage of 100-200 mg daily for a mean 11."1.27Treatment of chronic actinic dermatitis with azathioprine. ( Hawk, JL; Leigh, IM, 1984)
"Treatment with azathioprine (150 mg daily) improved the eczema."1.27Lymphocyte subsets in patients with compositae oleoresin dermatitis and increased UVA sensitivity during treatment with azathioprine. ( Baadsgaard, O; Geisler, C; Plesner, T; Thestrup-Pedersen, K, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199012 (52.17)18.7374
1990's2 (8.70)18.2507
2000's3 (13.04)29.6817
2010's4 (17.39)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Bourgaux, M1
Marcaillou, M1
Matei, I1
Delaumenie, S1
Prud'homme, R1
Souyri, N1
Bedane, C1
Alrashidi, A1
Rhodes, LE1
Sharif, JCH1
Kreeshan, FC1
Farrar, MD1
Ahad, T1
Milanesi, N1
Gola, M1
Francalanci, S1
Bhari, N1
Gupta, S1
de Carvalho, JF1
da Mota, LM1
Bonfa, E1
Shu, E1
Ichiki, Y1
Moriya, C1
Iwata, H1
Kitajima, Y1
Seishima, M1
Prasad, R1
De Silva, M1
O'Donovan, P2
Perrett, CM2
Zhang, X1
Montaner, B1
Xu, YZ1
Harwood, CA2
McGregor, JM2
Walker, SL2
Hanaoka, F1
Karran, P2
Warwick, J1
Roed-Petersen, J1
Thomsen, K1
Leigh, IM1
Hawk, JL3
Haynes, HA1
Bernhard, JD1
Gange, RW1
Luy, H1
Frenk, E1
Applegate, LA1
Elling, SV1
Murphy, GM2
Maurice, PD1
Norris, PG2
Morris, RW1
Baadsgaard, O2
Geisler, C1
Plesner, T1
Thestrup-Pedersen, K1
Buchness, MR1
Ashinoff, R1
Kingston, TP1
Lowe, NJ1
Sofen, HL1
Weingarten, DP1
de Castro, JL1
Pereira, MA1
Nunes, FP1
dos Santos, AP1
Lennard, L1
Thomas, S1
Harrington, CI1
Maddocks, JL1
Levantine, A1
Almeyda, J1

Reviews

1 review available for azathioprine and Actinic Reticuloid Syndrome

ArticleYear
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
    The British journal of dermatology, 1974, Volume: 90, Issue:2

    Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlor

1974

Trials

1 trial available for azathioprine and Actinic Reticuloid Syndrome

ArticleYear
Azathioprine treatment in chronic actinic dermatitis: a double-blind controlled trial with monitoring of exposure to ultraviolet radiation.
    The British journal of dermatology, 1989, Volume: 121, Issue:5

    Topics: Aged; Azathioprine; Clinical Trials as Topic; Double-Blind Method; Environmental Exposure; Female; H

1989

Other Studies

21 other studies available for azathioprine and Actinic Reticuloid Syndrome

ArticleYear
Man of stone: A case of a chronic actinic dermatitis mimicking a cutis verticis gyrata.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:3

    Topics: Aged; Azathioprine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Male; Photosensitivit

2020
Systemic drug photosensitivity-Culprits, impact and investigation in 122 patients.
    Photodermatology, photoimmunology & photomedicine, 2020, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Bone Density Conservation Agents; Child; D

2020
Photosensitivity in drug induced pellagra.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2019, Volume: 154, Issue:3

    Topics: Adolescent; Azathioprine; Colitis, Ulcerative; Drug Eruptions; Female; Humans; Immunosuppressive Age

2019
Tacrolimus 0.1% ointment applied under occlusion using cling film clears chronic actinic dermatitis resistant to systemic treatment.
    International journal of dermatology, 2017, Volume: 56, Issue:6

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Azathioprine; Chronic Disease; Humans; Immunos

2017
Fatal rhabdomyolysis in systemic lupus erythematosus.
    Rheumatology international, 2011, Volume: 31, Issue:9

    Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Antibodies, Antinuclear; Arthritis; Azathioprine;

2011
Three siblings with systemic lupus erythematosus.
    The Journal of dermatology, 2012, Volume: 39, Issue:2

    Topics: Adult; Antibodies, Antinuclear; Azathioprine; Dermatologic Agents; Exanthema; Female; HLA Antigens;

2012
Osteoporosis with underlying connective tissue disease: an unusual case.
    Annals of the New York Academy of Sciences, 2002, Volume: 966

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant

2002
Azathioprine and UVA light generate mutagenic oxidative DNA damage.
    Science (New York, N.Y.), 2005, Sep-16, Volume: 309, Issue:5742

    Topics: Adenine Phosphoribosyltransferase; Azathioprine; Cell Line; Cell Line, Tumor; DNA; DNA Damage; DNA R

2005
Azathioprine treatment photosensitizes human skin to ultraviolet A radiation.
    The British journal of dermatology, 2008, Volume: 159, Issue:1

    Topics: Adult; Azathioprine; Case-Control Studies; DNA Damage; Dose-Response Relationship, Radiation; Epider

2008
Azathioprin in the treatment of airborne contact dermatitis from compositae oleoresins and sensitivity to UVA.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:3

    Topics: Azathioprine; Dermatitis, Contact; Humans; Male; Middle Aged; Photosensitivity Disorders; Prednisone

1980
Treatment of chronic actinic dermatitis with azathioprine.
    The British journal of dermatology, 1984, Volume: 110, Issue:6

    Topics: Aged; Azathioprine; Chronic Disease; Female; Humans; Male; Middle Aged; Photosensitivity Disorders;

1984
Actinic reticuloid. Response to combination treatment with azathioprine, hydroxychloroquine, and prednisone.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:6

    Topics: Azathioprine; Drug Therapy, Combination; Humans; Hydroxychloroquine; Male; Middle Aged; Photosensiti

1984
Ultraviolet A-induced cellular membrane damage in the photosensitivity dermatitis/actinic reticuloid syndrome.
    Photodermatology, photoimmunology & photomedicine, 1994, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Betamethasone; Cell Line; Cell Membrane; Cell Survival; Cells

1994
Chronic actinic dermatitis associated with primary biliary cirrhosis.
    Clinical and experimental dermatology, 1997, Volume: 22, Issue:1

    Topics: Aged; Azathioprine; Chronic Disease; Female; Humans; Immunosuppressive Agents; Liver Cirrhosis, Bili

1997
Successful treatment of severe polymorphous light eruption with azathioprine.
    Archives of dermatology, 1989, Volume: 125, Issue:10

    Topics: Azathioprine; Erythema; Female; Humans; Middle Aged; Photosensitivity Disorders; Pruritus; PUVA Ther

1989
Lymphocyte subsets in patients with compositae oleoresin dermatitis and increased UVA sensitivity during treatment with azathioprine.
    Archives of dermatological research, 1985, Volume: 277, Issue:4

    Topics: Aged; Antibodies, Monoclonal; Azathioprine; Dermatitis, Contact; Female; Humans; Male; Middle Aged;

1985
Actinic reticuloid.
    Journal of the American Academy of Dermatology, 1987, Volume: 17, Issue:6

    Topics: Aged; Aged, 80 and over; Azathioprine; Black People; Combined Modality Therapy; Humans; Male; Photos

1987
Circulating and in situ lymphocyte subsets and Langerhans cells in patients with compositae oleoresin dermatitis and increased ultraviolet A sensitivity during treatment with azathioprine.
    Journal of the American Academy of Dermatology, 1986, Volume: 14, Issue:4

    Topics: Adult; Aged; Azathioprine; Cell Count; Dermatitis, Contact; Female; Fluorescent Antibody Technique;

1986
Actinic reticuloid in a black man: successful therapy with azathioprine.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:5 Pt 2

    Topics: Azathioprine; Black People; Dermatitis, Contact; Humans; Male; Middle Aged; Photosensitivity Disorde

1987
Successful treatment of a musk ambrette-sensitive persistent light reactor with azathioprine.
    Photo-dermatology, 1986, Volume: 3, Issue:4

    Topics: Azathioprine; Dinitrobenzenes; Humans; Male; Nitrobenzenes; Photosensitivity Disorders; Skin; Sunlig

1986
Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells.
    The British journal of dermatology, 1985, Volume: 113, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Drug Administration Schedule; Erythrocytes; Female; G

1985