Page last updated: 2024-10-23

azathioprine and Achondroplasia

azathioprine has been researched along with Achondroplasia in 1 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Achondroplasia: An autosomal dominant disorder that is the most frequent form of short-limb dwarfism. Affected individuals exhibit short stature caused by rhizomelic shortening of the limbs, characteristic facies with frontal bossing and mid-face hypoplasia, exaggerated lumbar lordosis, limitation of elbow extension, GENU VARUM, and trident hand. (Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim, MIM#100800, April 20, 2001)

Research Excerpts

ExcerptRelevanceReference
"Achondroplasia is the commonest skeletal dysplasia of autosomal dominant inheritance caused by "gain of function" mutations in the fibroblast growth factor receptor 3 (FGFR3) gene."2.82Myasthenia gravis complicating the surgical management of achondroplasia: a case-based update. ( Afshari, FT; Debenham, P; Parida, A; Solanki, GA, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Afshari, FT1
Parida, A1
Debenham, P1
Solanki, GA1

Reviews

1 review available for azathioprine and Achondroplasia

ArticleYear
Myasthenia gravis complicating the surgical management of achondroplasia: a case-based update.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2022, Volume: 38, Issue:10

    Topics: Achondroplasia; Anesthetics; Azathioprine; Child; Constriction, Pathologic; COVID-19; Female; Humans

2022