Page last updated: 2024-10-23

azathioprine and Acantholysis

azathioprine has been researched along with Acantholysis in 2 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Acantholysis: Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.

Research Excerpts

ExcerptRelevanceReference
"We describe three patients with pemphigus vulgaris, who during treatment with low doses of immunosuppressive drugs developed persistent keratotic or vegetating skin lesions."1.27Persistent vegetating and keratotic lesions in patients with pemphigus vulgaris during immunosuppressive therapy. ( Faber, WR; Flinterman, J; Neumann, HA, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faber, WR1
Neumann, HA1
Flinterman, J1
Newcomer, VD1
Landau, JW1

Reviews

1 review available for azathioprine and Acantholysis

ArticleYear
Recent advances in the diagnosis and treatment of pemphigus.
    California medicine, 1971, Volume: 114, Issue:2

    Topics: Acantholysis; Antigen-Antibody Reactions; Azathioprine; Biopsy; Complement Fixation Tests; Cyclophos

1971

Other Studies

1 other study available for azathioprine and Acantholysis

ArticleYear
Persistent vegetating and keratotic lesions in patients with pemphigus vulgaris during immunosuppressive therapy.
    The British journal of dermatology, 1983, Volume: 109, Issue:4

    Topics: Acantholysis; Aged; Azathioprine; Female; Humans; Immunosuppression Therapy; Keratosis; Male; Middle

1983