azathioprine has been researched along with Abnormalities, Congenital in 11 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There are only few studies with conflicting results on pregnancy outcome after paternal exposure to azathioprine or 6-mercaptopurine." | 7.78 | Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine. ( Allignol, A; Borisch, C; Hoeltzenbein, M; Meister, R; Schaefer, C; Weber-Schoendorfer, C, 2012) |
| "Azathioprine (AZA) is used during pregnancy by women with inflammatory bowel disease (IBD), other autoimmune disorders, malignancy, and organ transplantation." | 7.75 | Early pregnancy azathioprine use and pregnancy outcomes. ( Cleary, BJ; Källén, B, 2009) |
| "There are only few studies with conflicting results on pregnancy outcome after paternal exposure to azathioprine or 6-mercaptopurine." | 3.78 | Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine. ( Allignol, A; Borisch, C; Hoeltzenbein, M; Meister, R; Schaefer, C; Weber-Schoendorfer, C, 2012) |
| " Before conception and in early pregnancy, azathioprine and prednisone were administered in 48." | 3.75 | Follow-up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomes. ( Abrantes-Lemos, CP; Cançado, EL; Carrilho, FJ; Terrabuio, DR, 2009) |
| "Azathioprine (AZA) is used during pregnancy by women with inflammatory bowel disease (IBD), other autoimmune disorders, malignancy, and organ transplantation." | 3.75 | Early pregnancy azathioprine use and pregnancy outcomes. ( Cleary, BJ; Källén, B, 2009) |
| "Our primary aim was to assess infection rate and our secondary aims were to assess adverse reactions to vaccinations, growth, autoimmune diseases and malignancies." | 1.62 | Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life. ( Beukers, R; Bodelier, A; de Boer, N; de Lima, A; Depla, ACTM; Dijkstra, G; Erler, N; Escher, JC; Gilissen, L; Hoentjen, F; Jansen, JM; Kanis, SL; Kuyvenhoven, J; Mahmmod, N; Mallant-Hent, RC; Modderman, S; Noruzi, A; Oldenburg, B; Oostenbrug, LE; Pierik, M; Romberg-Camps, M; Ter Borg, PCJ; Thijs, W; van der Meulen-de Jong, AE; van der Woude, CJ; van Dijk, ARM; West, R, 2021) |
| "The outcomes were congenital abnormalities (CAs), preterm birth and small for gestational age (SGA)." | 1.46 | Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception: a nationwide cohort study. ( Friedman, S; Larsen, MD; Magnussen, B; Nørgård, BM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Ban, L | 1 |
| Tata, LJ | 1 |
| Fiaschi, L | 1 |
| Card, T | 1 |
| Brännström, M | 1 |
| Johannesson, L | 1 |
| Bokström, H | 1 |
| Kvarnström, N | 1 |
| Mölne, J | 1 |
| Dahm-Kähler, P | 1 |
| Enskog, A | 1 |
| Milenkovic, M | 1 |
| Ekberg, J | 1 |
| Diaz-Garcia, C | 1 |
| Gäbel, M | 1 |
| Hanafy, A | 1 |
| Hagberg, H | 1 |
| Olausson, M | 1 |
| Nilsson, L | 1 |
| Nørgård, BM | 1 |
| Magnussen, B | 1 |
| Larsen, MD | 1 |
| Friedman, S | 1 |
| Terrabuio, DR | 1 |
| Abrantes-Lemos, CP | 1 |
| Carrilho, FJ | 1 |
| Cançado, EL | 1 |
| Cleary, BJ | 1 |
| Källén, B | 1 |
| Akbari, M | 1 |
| Shah, S | 1 |
| Velayos, FS | 1 |
| Mahadevan, U | 1 |
| Cheifetz, AS | 1 |
| Hoeltzenbein, M | 1 |
| Weber-Schoendorfer, C | 1 |
| Borisch, C | 1 |
| Allignol, A | 1 |
| Meister, R | 1 |
| Schaefer, C | 1 |
| Martínez-Rueda, JO | 1 |
| Arce-Salinas, CA | 1 |
| Kraus, A | 1 |
| Alcocer-Varela, J | 1 |
| Alarcón-Segovia, D | 1 |
| Tuchmann-Duplessis, H | 1 |
| Eiseman, B | 1 |
| Kanis, SL | 1 |
| Modderman, S | 1 |
| Escher, JC | 1 |
| Erler, N | 1 |
| Beukers, R | 1 |
| de Boer, N | 1 |
| Bodelier, A | 1 |
| Depla, ACTM | 1 |
| Dijkstra, G | 1 |
| van Dijk, ARM | 1 |
| Gilissen, L | 1 |
| Hoentjen, F | 1 |
| Jansen, JM | 1 |
| Kuyvenhoven, J | 1 |
| Mahmmod, N | 1 |
| Mallant-Hent, RC | 1 |
| van der Meulen-de Jong, AE | 1 |
| Noruzi, A | 1 |
| Oldenburg, B | 1 |
| Oostenbrug, LE | 1 |
| Ter Borg, PCJ | 1 |
| Pierik, M | 1 |
| Romberg-Camps, M | 1 |
| Thijs, W | 1 |
| West, R | 1 |
| de Lima, A | 1 |
| van der Woude, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| First Clinical Live-Donor Uterus Transplantation Trial In Egypt[NCT03284073] | 11 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | |||
| Feasibility Study of Uterine Transplantation From Living Donors in Terms of Efficacy and Safety in Patients With Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH)[NCT03689842] | 20 participants (Anticipated) | Interventional | 2017-12-14 | Recruiting | |||
| Prospective Case Series of Human Uterus Transplantation From Live Donor[NCT01844362] | 9 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| Uterine Transplantation and Pregnancy Induction in Women Affected by Absolute Uterine Factor Infertility[NCT02656550] | 20 participants (Anticipated) | Interventional | 2015-11-11 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Abnormalities, Congenital
| Article | Year |
|---|---|
Systematic review and meta-analysis on the effects of thiopurines on birth outcomes from female and male patients with inflammatory bowel disease.
Topics: Azathioprine; Congenital Abnormalities; Female; Humans; Immunosuppressive Agents; Infant, Low Birth | 2013 |
10 other studies available for azathioprine and Abnormalities, Congenital
| Article | Year |
|---|---|
Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aminosalicylic Acids; Azathioprine; Congenital Abnormali | 2014 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Livebirth after uterus transplantation.
Topics: 46, XX Disorders of Sex Development; Adrenal Cortex Hormones; Adult; Apgar Score; Azathioprine; Cesa | 2015 |
Reassuring results on birth outcomes in children fathered by men treated with azathioprine/6-mercaptopurine within 3 months before conception: a nationwide cohort study.
Topics: Adult; Azathioprine; Case-Control Studies; Cohort Studies; Congenital Abnormalities; Denmark; Female | 2017 |
Follow-up of pregnant women with autoimmune hepatitis: the disease behavior along with maternal and fetal outcomes.
Topics: Abortion, Spontaneous; Adolescent; Adult; Azathioprine; Congenital Abnormalities; Female; Hepatitis, | 2009 |
Early pregnancy azathioprine use and pregnancy outcomes.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Inflammatory Agents; Azathioprine; Congenital Abnormalities | 2009 |
Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine.
Topics: Adult; Azathioprine; Congenital Abnormalities; Fathers; Female; Humans; Immunosuppressive Agents; Ma | 2012 |
Factors associated with fetal losses in severe systemic lupus erythematosus.
Topics: Adult; Analysis of Variance; Azathioprine; Case-Control Studies; Chloroquine; Cohort Studies; Congen | 1996 |
[The teratogenic risk].
Topics: Abnormalities, Drug-Induced; Animals; Azathioprine; Busulfan; Carbutamide; Congenital Abnormalities; | 1968 |
Liver transplantation.
Topics: Antilymphocyte Serum; Atrophy; Azathioprine; Biliary Tract; Congenital Abnormalities; Histocompatibi | 1970 |
Health outcomes of 1000 children born to mothers with inflammatory bowel disease in their first 5 years of life.
Topics: Adalimumab; Adult; Anti-Bacterial Agents; Autoimmune Diseases; Cesarean Section; Child Development; | 2021 |